Compile Data Set for Download or QSAR

Found 4 hits of ic50 for UniProtKB: P00533   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor [1-745,747-749,751-1210] (Homo sapiens (Human))	BDBM373725 (US10246444, Example 98) Show SMILES OC[C@H](O)COc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)C1CSSC1 |r| Show InChI InChI=1S/C30H26ClFN4O5S2/c31-24-7-21(4-5-27(24)40-13-17-2-1-3-20(32)6-17)35-29-18(10-33)11-34-25-9-28(41-14-22(38)12-37)26(8-23(25)29)36-30(39)19-15-42-43-16-19/h1-9,11,19,22,37-38H,12-16H2,(H,34,35)(H,36,39)/t22-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Research Hospital					Assay Description KINOMEscan is based on a competition binding assay that quantitatively measures the ability of a compound to compete with an immobilized, active-site...				J Med Chem 50: 1876-85 (2007) BindingDB Entry DOI: 10.7270/Q2NC63HJ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [1-745,747-749,751-1210] (Homo sapiens (Human))	BDBM373724 (US10246444, Example 95) Show SMILES OC[C@@H](O)COc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)C1CSSC1 |r| Show InChI InChI=1S/C30H26ClFN4O5S2/c31-24-7-21(4-5-27(24)40-13-17-2-1-3-20(32)6-17)35-29-18(10-33)11-34-25-9-28(41-14-22(38)12-37)26(8-23(25)29)36-30(39)19-15-42-43-16-19/h1-9,11,19,22,37-38H,12-16H2,(H,34,35)(H,36,39)/t22-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Research Hospital					Assay Description KINOMEscan is based on a competition binding assay that quantitatively measures the ability of a compound to compete with an immobilized, active-site...				J Med Chem 50: 1876-85 (2007) BindingDB Entry DOI: 10.7270/Q2NC63HJ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [1-745,747-749,751-1210] (Homo sapiens (Human))	BDBM373723 (US10246444, Example 90) Show SMILES OC[C@@H](O)COc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)CC1CSSC1 |r| Show InChI InChI=1S/C31H28ClFN4O5S2/c32-25-8-22(4-5-28(25)41-14-18-2-1-3-21(33)6-18)36-31-20(11-34)12-35-26-10-29(42-15-23(39)13-38)27(9-24(26)31)37-30(40)7-19-16-43-44-17-19/h1-6,8-10,12,19,23,38-39H,7,13-17H2,(H,35,36)(H,37,40)/t23-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Research Hospital					Assay Description KINOMEscan is based on a competition binding assay that quantitatively measures the ability of a compound to compete with an immobilized, active-site...				J Med Chem 50: 1876-85 (2007) BindingDB Entry DOI: 10.7270/Q2NC63HJ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [1-745,747-749,751-1210] (Homo sapiens (Human))	BDBM373712 (US10246444, Example 92) Show SMILES OC[C@H](O)COc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)CC1CSSC1 |r| Show InChI InChI=1S/C31H28ClFN4O5S2/c32-25-8-22(4-5-28(25)41-14-18-2-1-3-21(33)6-18)36-31-20(11-34)12-35-26-10-29(42-15-23(39)13-38)27(9-24(26)31)37-30(40)7-19-16-43-44-17-19/h1-6,8-10,12,19,23,38-39H,7,13-17H2,(H,35,36)(H,37,40)/t23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Research Hospital					Assay Description KINOMEscan is based on a competition binding assay that quantitatively measures the ability of a compound to compete with an immobilized, active-site...				J Med Chem 50: 1876-85 (2007) BindingDB Entry DOI: 10.7270/Q2NC63HJ
					More data for this Ligand-Target Pair