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Compile Data Set for Download or QSAR

Found 3 hits of kd for UniProtKB: P48067   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium- and chloride-dependent glycine transporter 1


(Homo sapiens (Human))
BDBM50126022
PNG
(CHEMBL26512 | {[3-(Biphenyl-4-yloxy)-3-(4-fluoro-p...)
Show SMILES CN(CCC(Oc1ccc(cc1)-c1ccccc1)c1ccc(F)cc1)CC(O)=O
Show InChI InChI=1S/C24H24FNO3/c1-26(17-24(27)28)16-15-23(20-7-11-21(25)12-8-20)29-22-13-9-19(10-14-22)18-5-3-2-4-6-18/h2-14,23H,15-17H2,1H3,(H,27,28)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
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CHEMBL
MCE
PC cid
PC sid
PDB
UniChem

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Similars

PubMed
n/an/an/a 0.800n/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards rat hippocampus GlyT1 transporter expressed in HEK 293 cells


Bioorg Med Chem Lett 13: 1291-2 (2003)


BindingDB Entry DOI: 10.7270/Q2JM291Q
More data for this
Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1


(Homo sapiens (Human))
BDBM50126022
PNG
(CHEMBL26512 | {[3-(Biphenyl-4-yloxy)-3-(4-fluoro-p...)
Show SMILES CN(CCC(Oc1ccc(cc1)-c1ccccc1)c1ccc(F)cc1)CC(O)=O
Show InChI InChI=1S/C24H24FNO3/c1-26(17-24(27)28)16-15-23(20-7-11-21(25)12-8-20)29-22-13-9-19(10-14-22)18-5-3-2-4-6-18/h2-14,23H,15-17H2,1H3,(H,27,28)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
PDB
UniChem

Patents


Similars

PubMed
n/an/an/a 1n/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human GlyT1 transporter expressed in HEK 293 cells


Bioorg Med Chem Lett 13: 1291-2 (2003)


BindingDB Entry DOI: 10.7270/Q2JM291Q
More data for this
Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1


(Homo sapiens (Human))
BDBM50126023
PNG
((Methyl-{3-[4-(4-methyl-benzoyl)-phenoxy]-3-phenyl...)
Show SMILES CN(CCC(Oc1ccc(cc1)C(=O)c1ccc(C)cc1)c1ccccc1)CC(O)=O
Show InChI InChI=1S/C26H27NO4/c1-19-8-10-21(11-9-19)26(30)22-12-14-23(15-13-22)31-24(20-6-4-3-5-7-20)16-17-27(2)18-25(28)29/h3-15,24H,16-18H2,1-2H3,(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/an/a 1.60n/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards rat hippocampus GlyT1 transporter expressed in HEK 293 cells


Bioorg Med Chem Lett 13: 1291-2 (2003)


BindingDB Entry DOI: 10.7270/Q2JM291Q
More data for this
Ligand-Target Pair