Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone deacetylase 4 [627-1085] (Homo sapiens (Human)) | BDBM50446481 (CHEMBL3110004 | US10011611, TMP269 | US10722597, C...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem | US Patent | n/a | n/a | 213 | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University | Assay Description I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ... | Bioorg Med Chem 17: 4894-9 (2009) BindingDB Entry DOI: 10.7270/Q2GT5QJ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 [627-1085] (Homo sapiens (Human)) | BDBM402284 ((N-hydroxy-4-((3-oxoisothiazolo[5,4-b]pyridin-2(3H...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University | Assay Description I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ... | Bioorg Med Chem 17: 4894-9 (2009) BindingDB Entry DOI: 10.7270/Q2GT5QJ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 [627-1085] (Homo sapiens (Human)) | BDBM50005711 (CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid PDB UniChem | US Patent | n/a | n/a | 5.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University | Assay Description I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ... | Bioorg Med Chem 17: 4894-9 (2009) BindingDB Entry DOI: 10.7270/Q2GT5QJ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 [627-1085] (Homo sapiens (Human)) | BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | 2.74E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Istanbul University | Assay Description I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ... | Bioorg Med Chem 17: 4894-9 (2009) BindingDB Entry DOI: 10.7270/Q2GT5QJ0 | |||||||||||
More data for this Ligand-Target Pair |