Compile Data Set for Download or QSAR

Found 13 hits of ic50 for UniProtKB: P36025   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Uncharacterized protein YOR062C (Agaricus bisporus (Mushroom))	BDBM166702 (5-(4-chlorophenyl)-3-[5-hydroxy-4-pyrone-2-yl-meth...) Show SMILES Nn1c(SCc2cc(=O)c(O)co2)nnc1-c1ccc(Cl)cc1 Show InChI InChI=1S/C14H13ClN4O3S/c1-23(12-6-10(20)11(21)7-22-12)14-18-17-13(19(14)16)8-2-4-9(15)5-3-8/h2-7,21,23H,16H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	6.8	n/a
Hunan University of Science and Technology					Assay Description The synthesized compounds were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substrate. Mushroom ...				Chem Biol Drug Des 86: 1087-92 (2015) Article DOI: 10.1111/cbdd.12577 BindingDB Entry DOI: 10.7270/Q2P26WW6
					More data for this Ligand-Target Pair
Uncharacterized protein YOR062C (Agaricus bisporus (Mushroom))	BDBM166703 (5-(2-chlorophenyl)-3-[5-hydroxy-4-pyrone-2-yl-meth...) Show SMILES Nn1c(SCc2cc(=O)c(O)co2)nnc1-c1ccccc1Cl Show InChI InChI=1S/C14H13ClN4O3S/c1-23(12-6-10(20)11(21)7-22-12)14-18-17-13(19(14)16)8-4-2-3-5-9(8)15/h2-7,21,23H,16H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.35E+3	n/a	n/a	n/a	n/a	6.8	n/a
Hunan University of Science and Technology					Assay Description The synthesized compounds were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substrate. Mushroom ...				Chem Biol Drug Des 86: 1087-92 (2015) Article DOI: 10.1111/cbdd.12577 BindingDB Entry DOI: 10.7270/Q2P26WW6
					More data for this Ligand-Target Pair
Uncharacterized protein YOR062C (Agaricus bisporus (Mushroom))	BDBM166704 (5-(2-bromophenyl)-3-[5-hydroxy-4-pyrone-2-yl-methy...) Show SMILES Nn1c(SCc2cc(=O)c(O)co2)nnc1-c1ccccc1Br Show InChI InChI=1S/C14H13BrN4O3S/c1-23(12-6-10(20)11(21)7-22-12)14-18-17-13(19(14)16)8-4-2-3-5-9(8)15/h2-7,21,23H,16H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.98E+3	n/a	n/a	n/a	n/a	6.8	n/a
Hunan University of Science and Technology					Assay Description The synthesized compounds were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substrate. Mushroom ...				Chem Biol Drug Des 86: 1087-92 (2015) Article DOI: 10.1111/cbdd.12577 BindingDB Entry DOI: 10.7270/Q2P26WW6
					More data for this Ligand-Target Pair
Uncharacterized protein YOR062C (Agaricus bisporus (Mushroom))	BDBM166697 (5-(4-methylphenyl)-3-[5-hydroxy-4-pyrone-2-yl-meth...) Show SMILES Cc1ccc(cc1)-c1nnc(SCc2cc(=O)c(O)co2)n1N Show InChI InChI=1S/C15H16N4O3S/c1-9-3-5-10(6-4-9)14-17-18-15(19(14)16)23(2)13-7-11(20)12(21)8-22-13/h3-8,21,23H,16H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.25E+3	n/a	n/a	n/a	n/a	6.8	n/a
Hunan University of Science and Technology					Assay Description The synthesized compounds were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substrate. Mushroom ...				Chem Biol Drug Des 86: 1087-92 (2015) Article DOI: 10.1111/cbdd.12577 BindingDB Entry DOI: 10.7270/Q2P26WW6
					More data for this Ligand-Target Pair
Uncharacterized protein YOR062C (Agaricus bisporus (Mushroom))	BDBM166698 (5-(3-methylphenyl)-3-[5-hydroxy-4-pyrone-2-yl-meth...) Show SMILES Cc1cccc(c1)-c1nnc(SCc2cc(=O)c(O)co2)n1N Show InChI InChI=1S/C15H16N4O3S/c1-9-4-3-5-10(6-9)14-17-18-15(19(14)16)23(2)13-7-11(20)12(21)8-22-13/h3-8,21,23H,16H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.82E+3	n/a	n/a	n/a	n/a	6.8	n/a
Hunan University of Science and Technology					Assay Description The synthesized compounds were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substrate. Mushroom ...				Chem Biol Drug Des 86: 1087-92 (2015) Article DOI: 10.1111/cbdd.12577 BindingDB Entry DOI: 10.7270/Q2P26WW6
					More data for this Ligand-Target Pair
Uncharacterized protein YOR062C (Agaricus bisporus (Mushroom))	BDBM166699 (5-(2-methylphenyl)-3-[5-hydroxy-4-pyrone-2-yl-meth...) Show SMILES Cc1ccccc1-c1nnc(SCc2cc(=O)c(O)co2)n1N Show InChI InChI=1S/C15H16N4O3S/c1-9-5-3-4-6-10(9)14-17-18-15(19(14)16)23(2)13-7-11(20)12(21)8-22-13/h3-8,21,23H,16H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.12E+3	n/a	n/a	n/a	n/a	6.8	n/a
Hunan University of Science and Technology					Assay Description The synthesized compounds were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substrate. Mushroom ...				Chem Biol Drug Des 86: 1087-92 (2015) Article DOI: 10.1111/cbdd.12577 BindingDB Entry DOI: 10.7270/Q2P26WW6
					More data for this Ligand-Target Pair
Uncharacterized protein YOR062C (Agaricus bisporus (Mushroom))	BDBM166696 (5-phenyl-3-[5-hydroxy-4-pyrone-2-yl-methylmercapto...) Show SMILES Nn1c(SCc2cc(=O)c(O)co2)nnc1-c1ccccc1 Show InChI InChI=1S/C14H14N4O3S/c1-22(12-7-10(19)11(20)8-21-12)14-17-16-13(18(14)15)9-5-3-2-4-6-9/h2-8,20,22H,15H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.45E+3	n/a	n/a	n/a	n/a	6.8	n/a
Hunan University of Science and Technology					Assay Description The synthesized compounds were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substrate. Mushroom ...				Chem Biol Drug Des 86: 1087-92 (2015) Article DOI: 10.1111/cbdd.12577 BindingDB Entry DOI: 10.7270/Q2P26WW6
					More data for this Ligand-Target Pair
Uncharacterized protein YOR062C (Agaricus bisporus (Mushroom))	BDBM166700 (5-(4-methoxylphenyl)-3-[5-hydroxy-4-pyrone-2-yl-me...) Show SMILES COc1ccc(cc1)-c1nnc(SCc2cc(=O)c(O)co2)n1N Show InChI InChI=1S/C15H16N4O4S/c1-22-10-5-3-9(4-6-10)14-17-18-15(19(14)16)24(2)13-7-11(20)12(21)8-23-13/h3-8,21,24H,16H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a	6.8	n/a
Hunan University of Science and Technology					Assay Description The synthesized compounds were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substrate. Mushroom ...				Chem Biol Drug Des 86: 1087-92 (2015) Article DOI: 10.1111/cbdd.12577 BindingDB Entry DOI: 10.7270/Q2P26WW6
					More data for this Ligand-Target Pair
Uncharacterized protein YOR062C (Agaricus bisporus (Mushroom))	BDBM166701 (5-(2-methoxylphenyl)-3-[5-hydroxy-4-pyrone-2-yl-me...) Show SMILES COc1ccccc1-c1nnc(SCc2cc(=O)c(O)co2)n1N Show InChI InChI=1S/C15H16N4O4S/c1-22-12-6-4-3-5-9(12)14-17-18-15(19(14)16)24(2)13-7-10(20)11(21)8-23-13/h3-8,21,24H,16H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.32E+4	n/a	n/a	n/a	n/a	6.8	n/a
Hunan University of Science and Technology					Assay Description The synthesized compounds were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substrate. Mushroom ...				Chem Biol Drug Des 86: 1087-92 (2015) Article DOI: 10.1111/cbdd.12577 BindingDB Entry DOI: 10.7270/Q2P26WW6
					More data for this Ligand-Target Pair
Uncharacterized protein YOR062C (Agaricus bisporus (Mushroom))	BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...) Show SMILES OCc1cc(=O)c(O)co1 Show InChI InChI=1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	6.8	n/a
Hunan University of Science and Technology					Assay Description The synthesized compounds were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substrate. Mushroom ...				Chem Biol Drug Des 86: 1087-92 (2015) Article DOI: 10.1111/cbdd.12577 BindingDB Entry DOI: 10.7270/Q2P26WW6
					More data for this Ligand-Target Pair
Uncharacterized protein YOR062C (Agaricus bisporus (Mushroom))	BDBM166694 (5-ethyl-3-[5-hydroxy-4-pyrone-2-yl-methylmercapto]...) Show SMILES CCc1nnc(SCc2cc(=O)c(O)co2)n1N Show InChI InChI=1S/C10H14N4O3S/c1-3-8-12-13-10(14(8)11)18(2)9-4-6(15)7(16)5-17-9/h4-5,16,18H,3,11H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.57E+4	n/a	n/a	n/a	n/a	6.8	n/a
Hunan University of Science and Technology					Assay Description The synthesized compounds were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substrate. Mushroom ...				Chem Biol Drug Des 86: 1087-92 (2015) Article DOI: 10.1111/cbdd.12577 BindingDB Entry DOI: 10.7270/Q2P26WW6
					More data for this Ligand-Target Pair
Uncharacterized protein YOR062C (Agaricus bisporus (Mushroom))	BDBM166695 (5-propyl-3-[5-hydroxy-4-pyrone-2-yl-methylmercapto...) Show SMILES CCCc1nnc(SCc2cc(=O)c(O)co2)n1N Show InChI InChI=1S/C11H16N4O3S/c1-3-4-9-13-14-11(15(9)12)19(2)10-5-7(16)8(17)6-18-10/h5-6,17,19H,3-4,12H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.82E+4	n/a	n/a	n/a	n/a	6.8	n/a
Hunan University of Science and Technology					Assay Description The synthesized compounds were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substrate. Mushroom ...				Chem Biol Drug Des 86: 1087-92 (2015) Article DOI: 10.1111/cbdd.12577 BindingDB Entry DOI: 10.7270/Q2P26WW6
					More data for this Ligand-Target Pair
Uncharacterized protein YOR062C (Agaricus bisporus (Mushroom))	BDBM166693 (5-methyl-3-[5-hydroxy-4-pyrone-2-yl-methylmercapto...) Show SMILES Cc1nnc(SCc2cc(=O)c(O)co2)n1N Show InChI InChI=1S/C9H12N4O3S/c1-5-11-12-9(13(5)10)17(2)8-3-6(14)7(15)4-16-8/h3-4,15,17H,10H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.10E+4	n/a	n/a	n/a	n/a	6.8	n/a
Hunan University of Science and Technology					Assay Description The synthesized compounds were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substrate. Mushroom ...				Chem Biol Drug Des 86: 1087-92 (2015) Article DOI: 10.1111/cbdd.12577 BindingDB Entry DOI: 10.7270/Q2P26WW6
					More data for this Ligand-Target Pair