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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for UniProtKB: P48730   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Casein kinase I isoform delta


(Homo sapiens (Human))		BDBM50455466
PNG
(CHEMBL4204681)
Show SMILES COc1ccc(Cn2c(SCC(=O)Nc3nc4ccc(cc4s3)C(F)(F)F)nc3CCSc3c2=O)cc1
Show InChI InChI=1S/C24H19F3N4O3S3/c1-34-15-5-2-13(3-6-15)11-31-21(33)20-17(8-9-35-20)29-23(31)36-12-19(32)30-22-28-16-7-4-14(24(25,26)27)10-18(16)37-22/h2-7,10H,8-9,11-12H2,1H3,(H,28,30,32)
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.47E+3n/an/an/an/a



Ulm University Hospital

Curated by ChEMBL


Assay Description
Inhibition of CK1delta in HEK293T cells assessed as stimulation of Wnt/beta-catenin signaling after 22 hrs in presence of Wnt3A-conditioned medium by...

J Med Chem 61: 4087-4102 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00095
BindingDB Entry DOI: 10.7270/Q2GX4F5D
More data for this
Ligand-Target Pair