Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Mus musculus (Mouse)) | BDBM198031 (US9221795, 27) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.17E+3 | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of PI3K p110alpha in mouse embryonic fibroblast cells assessed as reduction in PDGF-induced AKT phosphorylation at S473 residue preincubat... | Citation and Details Article DOI: 10.1021/acs.jmedchem.6b01169 BindingDB Entry DOI: 10.7270/Q20G3PV2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Mus musculus (Mouse)) | BDBM50449964 (CHEMBL4174988) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of PI3Kalpha in mouse NIH-3T3 cells assessed as reduction in PDGF-BB-induced phosphorylation of AKT at Thr308 residues preincubated for 1 ... | Eur J Med Chem 156: 831-846 (2018) Article DOI: 10.1016/j.ejmech.2018.07.036 BindingDB Entry DOI: 10.7270/Q2BR8VRJ | |||||||||||
More data for this Ligand-Target Pair |