Compile Data Set for Download or QSAR

Found 269 hits of ec50 for UniProtKB: P0C6X1   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Replicase polyprotein 1ab (HCoV-229E)	BDBM648427 (US20240033256, Compound 2) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	6.5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM50281169 (CHEMBL4173846 | US20240034730, Compound 1) Show SMILES Oc1nn2ccccc2c1C(=O)Nc1c(F)c(F)c(-c2ccccc2)c(F)c1F Show InChI InChI=1S/C20H11F4N3O2/c21-14-12(10-6-2-1-3-7-10)15(22)17(24)18(16(14)23)25-19(28)13-11-8-4-5-9-27(11)26-20(13)29/h1-9H,(H,25,28)(H,26,29)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	MCE PC cid PC sid PDB UniChem Similars		n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM15339 (6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methyl-qui...) Show SMILES Cc1c(nc2ccc(F)cc2c1C(O)=O)-c1ccc(cc1)-c1ccccc1F Show InChI InChI=1S/C23H15F2NO2/c1-13-21(23(27)28)18-12-16(24)10-11-20(18)26-22(13)15-8-6-14(7-9-15)17-4-2-3-5-19(17)25/h2-12H,1H3,(H,27,28)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars		n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM648428 (US20240033256, Compound 3) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	25.4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM429505 (Remdesivir | US20240034730, Compound Remdesivir | ...) Show SMILES CCC(CC)COC(=O)[C@H](C)N[P@](=O)(OC[C@H]1O[C@](C#N)([C@H](O)[C@@H]1O)c1ccc2c(N)ncnn12)Oc1ccccc1 Show InChI InChI=1S/C27H35N6O8P/c1-4-18(5-2)13-38-26(36)17(3)32-42(37,41-19-9-7-6-8-10-19)39-14-21-23(34)24(35)27(15-28,40-21)22-12-11-20-25(29)30-16-31-33(20)22/h6-12,16-18,21,23-24,34-35H,4-5,13-14H2,1-3H3,(H,32,37)(H2,29,30,31)/t17-,21+,23+,24+,27-,42-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem		n/a	n/a	n/a	n/a	35	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM648426 (US20240033256, Compound 1) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	71.4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM484195 (UAWJ9-36-3) Show SMILES CC1(C)[C@H]2CN([C@@H]([C@@H]12)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C=O)C(=O)OCc1ccccc1 Show InChI InChI=1S/C23H29N3O5/c1-23(2)17-11-26(22(30)31-13-14-6-4-3-5-7-14)19(18(17)23)21(29)25-16(12-27)10-15-8-9-24-20(15)28/h3-7,12,15-19H,8-11,13H2,1-2H3,(H,24,28)(H,25,29)/t15-,16-,17-,18-,19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
The University of Arizona					Assay Description Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...				ACS Pharmacol Transl Sci 4: 1408-1421 (2021) Article DOI: 10.1021/acsptsci.1c00099 BindingDB Entry DOI: 10.7270/Q20V8GWQ
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM484194 (UAWJ9-36-1) Show SMILES O=C[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@@H]1[C@H]2CCC[C@H]2CN1C(=O)OCc1ccccc1 Show InChI InChI=1S/C23H29N3O5/c27-13-18(11-16-9-10-24-21(16)28)25-22(29)20-19-8-4-7-17(19)12-26(20)23(30)31-14-15-5-2-1-3-6-15/h1-3,5-6,13,16-20H,4,7-12,14H2,(H,24,28)(H,25,29)/t16-,17-,18-,19-,20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	170	n/a	n/a	n/a	n/a
The University of Arizona					Assay Description Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...				ACS Pharmacol Transl Sci 4: 1408-1421 (2021) Article DOI: 10.1021/acsptsci.1c00099 BindingDB Entry DOI: 10.7270/Q20V8GWQ
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM448319 (GC-376 | GC376) Show SMILES CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC1CCNC1=O)C(O)S([O-])(=O)=O Show InChI InChI=1S/C21H31N3O8S/c1-13(2)10-16(24-21(28)32-12-14-6-4-3-5-7-14)19(26)23-17(20(27)33(29,30)31)11-15-8-9-22-18(15)25/h3-7,13,15-17,20,27H,8-12H2,1-2H3,(H,22,25)(H,23,26)(H,24,28)(H,29,30,31)/p-1/t15?,16-,17-,20?/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a
The University of Arizona					Assay Description Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...				ACS Pharmacol Transl Sci 4: 1408-1421 (2021) Article DOI: 10.1021/acsptsci.1c00099 BindingDB Entry DOI: 10.7270/Q20V8GWQ
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM476337 (US10874687, Compound 1A) Show SMILES CNc1nc(N)nc2n(cnc12)[C@@H]1O[C@H](CO[P@@](=O)(N[C@@H](C)C(=O)OC(C)C)Oc2ccccc2)[C@@H](O)[C@@]1(C)F |r| Show InChI InChI=1S/C24H33FN7O7P/c1-13(2)37-21(34)14(3)31-40(35,39-15-9-7-6-8-10-15)36-11-16-18(33)24(4,25)22(38-16)32-12-28-17-19(27-5)29-23(26)30-20(17)32/h6-10,12-14,16,18,22,33H,11H2,1-5H3,(H,31,35)(H3,26,27,29,30)/t14-,16+,18+,22+,24+,40-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
Atea Pharmaceuticals, Inc. US Patent					Assay Description Compound activity against coronavirus was based on inhibition of virus induced cytopathogenicity acutely infected with a multiplicity of infection (m...				US Patent US10874687 (2020) BindingDB Entry DOI: 10.7270/Q22B9238
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM476337 (US10874687, Compound 1A) Show SMILES CNc1nc(N)nc2n(cnc12)[C@@H]1O[C@H](CO[P@@](=O)(N[C@@H](C)C(=O)OC(C)C)Oc2ccccc2)[C@@H](O)[C@@]1(C)F |r| Show InChI InChI=1S/C24H33FN7O7P/c1-13(2)37-21(34)14(3)31-40(35,39-15-9-7-6-8-10-15)36-11-16-18(33)24(4,25)22(38-16)32-12-28-17-19(27-5)29-23(26)30-20(17)32/h6-10,12-14,16,18,22,33H,11H2,1-5H3,(H,31,35)(H3,26,27,29,30)/t14-,16+,18+,22+,24+,40-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
Atea Pharmaceuticals, Inc. US Patent					Assay Description Compound activity against coronavirus was based on inhibition of virus induced cytopathogenicity acutely infected with a multiplicity of infection (m...				US Patent US10874687 (2020) BindingDB Entry DOI: 10.7270/Q22B9238
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM496896 (US11312704, Compound 101 | US11351149, Example 49 ...) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N Show InChI InChI=1S/C23H29N5O4/c1-13(2)9-18(22(30)26-15(12-24)10-14-7-8-25-21(14)29)28-23(31)19-11-16-17(27-19)5-4-6-20(16)32-3/h4-6,11,13-15,18,27H,7-10H2,1-3H3,(H,25,29)(H,26,30)(H,28,31)/t14-,15-,18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509781 (US11124497, Compound 103 | US11312704, Compound 10...) Show SMILES CC(C)C[C@H](NC(=O)c1nc2ccccc2[nH]1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509782 (US11124497, Compound 127 | US11124497, Compound 13...) Show SMILES CC(C)C[C@H](NC(=O)c1nc2cccc(Cl)c2[nH]1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509786 (US11124497, Compound 134 | US11472793, Compound 13...) Show SMILES COc1cccc2[nH]c(cc12)C(=O)NC(CC(C)C)C(=O)NC(CC1CCNC1=O)C(O)C#N Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM576978 (US11472793, Compound 134 (Isomer 1)) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C[C@H]1CCNC1=O)C(O)C#N |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM576979 (US11472793, Compound 134 (Isomer 2) | US11472793, ...) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(O)C#N |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509789 (US11124497, Compound 135 | US11312704, Compound 13...) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(O)C#N |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM576979 (US11472793, Compound 134 (Isomer 2) | US11472793, ...) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(O)C#N |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509800 (US11124497, Compound 171 | US11312704, Compound 17...) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N1C[C@@H](C[C@H]1C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N)c1ccccc1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509802 (US11124497, Compound 185 | US11312704, Compound 18...) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N[C@@H](CC1CCCCC1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509803 (US11124497, Compound 197 | US11312704, Compound 19...) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N1C[C@H]2C([C@H]1C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N)C2(C)C |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509805 (US11124497, Compound 205 | US11312704, Compound 20...) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N[C@@H](CC1CC1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM577023 (US11472793, Compound 323 (Isomer 1)) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(NC(C)(C)C)C#N |r,w:30.33| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM577024 (US11472793, Compound 323 (Isomer 2)) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(NC(C)(C)C)C#N |r,w:30.33| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM550864 (US11312704, Compound 329 | US11472793, Compound 32...) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(N[C@@H](C)c1ccccc1)C#N |r,w:30.33| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509837 (US11124497, Compound 331 (Isomer 1) | US11312704, ...) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)[C@H](C#N)N1CCCC1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509838 (US11124497, Compound 331 (Isomer 2) | US11312704, ...) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)[C@@H](C#N)N1CCCC1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509839 (US11124497, Compound 344D | US11312704, Compound 3...) Show SMILES COc1cccc2[nH]c(cc12)C(=O)NC(CC(C)C)C(=O)NC(CC1CCNC1=O)C=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509840 (US11124497, Compound 344C | US11312704, Compound 3...) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1CCNC1=O)C(N)C#N |r,w:30.33| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509841 (US11124497, Compound 344A | US11312704, Compound 3...) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N1C[C@@H](CC1C(=O)N[C@@H](C[C@@H]1CCNC1=O)C=O)c1ccccc1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509842 (US11124497, Compound 345 | US11312704, Compound 34...) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N1C[C@@H](C[C@H]1C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(O)C#N)c1ccccc1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM577034 (US11472793, Compound 345 (Isomer 1)) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N1C[C@H](C[C@H]1C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(O)C#N)c1ccccc1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509842 (US11124497, Compound 345 | US11312704, Compound 34...) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N1C[C@@H](C[C@H]1C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(O)C#N)c1ccccc1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509848 (US11124497, Compound 361 | US11312704, Compound 36...) Show SMILES CC(C)C[C@H](NC(=O)c1cc2c(OC(F)(F)F)cccc2[nH]1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509849 (US11124497, Compound 363 | US11312704, Compound 36...) Show SMILES CC(C)C[C@H](NC(=O)c1nc2c(OC(F)(F)F)cccc2[nH]1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509854 (US11124497, Compound 375A | US11312704, Compound 3...) Show SMILES O=C(N[C@@H](C[C@@H]1CCNC1=O)C#N)[C@H](CC1CC1)NC(=O)c1cc2c(cccc2[nH]1)C1CC1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509855 (US11124497, Compound 377 | US11312704, Compound 37...) Show SMILES CCOc1cccc2[nH]c(cc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509856 (US11124497, Compound 379 | US11312704, Compound 37...) Show SMILES CCCOc1cccc2[nH]c(cc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509858 (US11124497, Compound 385 (Isomer 1) | US11312704, ...) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N1C[C@@H](C[C@H]1C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N)C12CC(C1)C2 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509859 (US11124497, Compound 385 (Isomer 2) | US11312704, ...) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N1C[C@H](C[C@H]1C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N)C12CC(C1)C2 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM577052 (US11472793, Compound 389A (Isomer 1) | US11524940,...) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N1CC2(CC1C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N)CCCCC2 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509863 (US11124497, Compound 393 | US11312704, Compound 39...) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N1C[C@@H]2CCC[C@@H]2[C@H]1C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509866 (US11124497, Compound 397 | US11312704, Compound 39...) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N1CC2(CC2)C[C@H]1C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM577058 (US11472793, Compound 399 (Isomer 1) | US11524940, ...) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N1CC2(CCC2)C[C@H]1C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509868 (US11124497, Compound 401 | US11312704, Compound 40...) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N1CC2(CCCC2)C[C@H]1C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509869 (US11124497, Compound 401 (Isomer 1) | US11124497, ...) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N1C[C@@]2(CCCC2)C[C@H]1C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509871 (US11124497, Compound 405 | US11312704, Compound 40...) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N[C@@H](CC(C)(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509872 (US11124497, Compound 407 | US11312704, Compound 40...) Show SMILES CO[C@@H]1C[C@H](N(C1)C(=O)c1cc2c(OC)cccc2[nH]1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM509908 (US11124497, Compound 491 | US11124497, Compound 49...) Show SMILES COc1cccc2[nH]c(cc12)C(=O)N[C@@H](CC1CC1)C(=O)N[C@@H](C[C@@H]1CCCNC1=O)C#N |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56P00
					More data for this Ligand-Target Pair

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