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Compile Data Set for Download or QSAR

Found 6 hits of kd for UniProtKB: P23219   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin G/H synthase 1


(Homo sapiens (Human))
BDBM50486822
PNG
(CHEBI:76249 | Miroprofen)
Show SMILES CC(C(O)=O)c1ccc(cc1)-c1cn2ccccc2n1
Show InChI InChI=1S/C16H14N2O2/c1-11(16(19)20)12-5-7-13(8-6-12)14-10-18-9-3-2-4-15(18)17-14/h2-11H,1H3,(H,19,20)
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Article
n/an/an/a 185n/an/an/an/an/a


TBA

Assay Description
Binding affinity to COX1 (unknown origin)


Citation and Details

Article DOI: 10.1007/s00044-011-9870-3
BindingDB Entry DOI: 10.7270/Q2GM8B61
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Homo sapiens (Human))
BDBM50486823
PNG
(CHEMBL2235866)
Show SMILES Nc1c(nc2ccccn12)C(O)=O
Show InChI InChI=1S/C8H7N3O2/c9-7-6(8(12)13)10-5-3-1-2-4-11(5)7/h1-4H,9H2,(H,12,13)
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PC sid
UniChem
Article
n/an/an/a 262n/an/an/an/an/a


TBA

Assay Description
Binding affinity to COX1 (unknown origin)


Citation and Details

Article DOI: 10.1007/s00044-011-9870-3
BindingDB Entry DOI: 10.7270/Q2GM8B61
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Homo sapiens (Human))
BDBM50486825
PNG
(CHEMBL2235865)
Show SMILES OC(=O)c1nc2ccccn2c1[N+]([O-])=O
Show InChI InChI=1S/C8H5N3O4/c12-8(13)6-7(11(14)15)10-4-2-1-3-5(10)9-6/h1-4H,(H,12,13)
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antibodypedia
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PC cid
PC sid
UniChem
Article
n/an/an/a 16n/an/an/an/an/a


TBA

Assay Description
Binding affinity to COX1 (unknown origin)


Citation and Details

Article DOI: 10.1007/s00044-011-9870-3
BindingDB Entry DOI: 10.7270/Q2GM8B61
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Homo sapiens (Human))
BDBM17638
PNG
(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1
Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)
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MCE
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MMDB
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Similars

Article
n/an/an/a 253n/an/an/an/an/a


TBA

Assay Description
Binding affinity to COX1 (unknown origin)


Citation and Details

Article DOI: 10.1007/s00044-011-9870-3
BindingDB Entry DOI: 10.7270/Q2GM8B61
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Homo sapiens (Human))
BDBM50427217
PNG
(CHEMBL2324850)
Show SMILES OC(=O)c1cn2ccccc2n1
Show InChI InChI=1S/C8H6N2O2/c11-8(12)6-5-10-4-2-1-3-7(10)9-6/h1-5H,(H,11,12)
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CHEMBL
MCE
PC cid
PC sid
UniChem
Article
n/an/an/a 1.54E+3n/an/an/an/an/a


TBA

Assay Description
Binding affinity to COX1 (unknown origin)


Citation and Details

Article DOI: 10.1007/s00044-011-9870-3
BindingDB Entry DOI: 10.7270/Q2GM8B61
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase 1


(Homo sapiens (Human))
BDBM50486824
PNG
(CHEMBL2235864)
Show SMILES CCOC(=O)c1nc2ccccn2c1[N+]([O-])=O
Show InChI InChI=1S/C10H9N3O4/c1-2-17-10(14)8-9(13(15)16)12-6-4-3-5-7(12)11-8/h3-6H,2H2,1H3
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PC cid
PC sid
UniChem
Article
n/an/an/a 1.04E+3n/an/an/an/an/a


TBA

Assay Description
Binding affinity to COX1 (unknown origin)


Citation and Details

Article DOI: 10.1007/s00044-011-9870-3
BindingDB Entry DOI: 10.7270/Q2GM8B61
More data for this
Ligand-Target Pair