Found 8 hits of kd for UniProtKB: P0A031 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cell division protein FtsZ
(Staphylococcus aureus) | BDBM50589185
(CHEMBL5199894)Show SMILES COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\N1CCCCC1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1039/d1md00249j
BindingDB Entry DOI: 10.7270/Q20P140J |
More data for this
Ligand-Target Pair | |
Cell division protein FtsZ
(Staphylococcus aureus) | BDBM50402381
(CHEMBL2207296)Show SMILES COc1cc2cc(-c3cccc(c3)-c3ccc(cc3)-c3ccccc3)[n+](C)c(C)c2cc1OC Show InChI InChI=1S/C31H28NO2/c1-21-28-20-31(34-4)30(33-3)19-27(28)18-29(32(21)2)26-12-8-11-25(17-26)24-15-13-23(14-16-24)22-9-6-5-7-10-22/h5-20H,1-4H3/q+1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a |
The State University of New Jersey
Curated by ChEMBL
| Assay Description
Binding affinity to Staphylococcus aureus FtsZ expressed in Escherichia coli cells assessed as dissociation constant by fluorescence spectroscopy |
Bioorg Med Chem 20: 7012-29 (2012)
Article DOI: 10.1016/j.bmc.2012.10.009
BindingDB Entry DOI: 10.7270/Q23779VJ |
More data for this
Ligand-Target Pair | |
Cell division protein FtsZ
(Staphylococcus aureus) | BDBM50605151
(CHEMBL5188114)Show SMILES [I-].CCCCCNc1cc(\C=C\c2ccc(cc2)N(C)C)[n+](C)c2ccccc12 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 2.38E+3 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114360
BindingDB Entry DOI: 10.7270/Q2QF8Z07 |
More data for this
Ligand-Target Pair | |
Cell division protein FtsZ
(Staphylococcus aureus) | BDBM50605149
(CHEMBL5200927)Show SMILES [I-].CN(C)c1ccc(\C=C\c2cc(N3CCCCC3)c3ccccc3[n+]2C)cc1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 2.49E+3 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114360
BindingDB Entry DOI: 10.7270/Q2QF8Z07 |
More data for this
Ligand-Target Pair | |
Cell division protein FtsZ
(Staphylococcus aureus) | BDBM50399003
(CHEMBL2180486)Show SMILES [#6]C([#6])([#6])c1ccc(cc1)-c1cccc(-[#6]\[#7]=[#6](\[#7])-[#7])c1 Show InChI InChI=1S/C18H23N3/c1-18(2,3)16-9-7-14(8-10-16)15-6-4-5-13(11-15)12-21-17(19)20/h4-11H,12H2,1-3H3,(H4,19,20,21) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a |
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
| Assay Description
Binding affinity to Staphylococcus aureus FtsZ expressed in Escherichia coli BL21 (DE3) at 25 degC by fluorescence anisotropy assay |
J Med Chem 55: 10160-76 (2012)
Article DOI: 10.1021/jm3012728
BindingDB Entry DOI: 10.7270/Q2ZG6TC8 |
More data for this
Ligand-Target Pair | |
Cell division protein FtsZ
(Staphylococcus aureus) | BDBM50605150
(CHEMBL5174791)Show SMILES [I-].CC1CCN(CC1)c1cc(\C=C\c2ccc(cc2)N(C)C)[n+](C)c2ccccc12 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 3.84E+3 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114360
BindingDB Entry DOI: 10.7270/Q2QF8Z07 |
More data for this
Ligand-Target Pair | |
Cell division protein FtsZ
(Staphylococcus aureus) | BDBM50605152
(CHEMBL5186593)Show SMILES [I-].CC1CCN(CC1)c1cc(\C=C\c2ccc(cc2)N(C)C)c2ccccc2[n+]1C | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 3.86E+3 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114360
BindingDB Entry DOI: 10.7270/Q2QF8Z07 |
More data for this
Ligand-Target Pair | |
Cell division protein FtsZ
(Staphylococcus aureus) | BDBM50402380
(CHEMBL2207300)Show SMILES COc1cc2cc(-c3cccc(c3)-c3ccc(cc3)C(C)(C)C)[n+](C)c(C)c2cc1OC Show InChI InChI=1S/C29H32NO2/c1-19-25-18-28(32-7)27(31-6)17-23(25)16-26(30(19)5)22-10-8-9-21(15-22)20-11-13-24(14-12-20)29(2,3)4/h8-18H,1-7H3/q+1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a | n/a |
The State University of New Jersey
Curated by ChEMBL
| Assay Description
Binding affinity to Staphylococcus aureus FtsZ expressed in Escherichia coli cells assessed as dissociation constant by fluorescence spectroscopy |
Bioorg Med Chem 20: 7012-29 (2012)
Article DOI: 10.1016/j.bmc.2012.10.009
BindingDB Entry DOI: 10.7270/Q23779VJ |
More data for this
Ligand-Target Pair | |
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