Compile Data Set for Download or QSAR

Found 4 hits of ic50 data for polymerid = 7874   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 16 (Homo sapiens (Human))	BDBM126500 (US11591322, Compound NVP-2 | US8778951, 310) Show SMILES COC[C@@H](C)N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NCC2(CCOCC2)C#N)n1 |r,wU:9.12,wD:6.5,3.3,(7.56,1.68,;6.23,2.45,;4.9,1.68,;3.56,2.45,;3.56,3.99,;2.23,1.68,;.89,2.45,;.89,3.99,;-.44,4.76,;-1.77,3.99,;-1.77,2.45,;-.44,1.68,;-3.11,4.76,;-4.44,3.99,;-4.44,2.45,;-5.77,1.68,;-7.11,2.45,;-8.44,1.68,;-7.11,3.99,;-5.77,4.76,;-5.77,.14,;-7.11,-.63,;-7.11,-2.17,;-5.77,-2.94,;-4.44,-2.17,;-3.11,-2.94,;-1.77,-2.17,;-.44,-2.94,;-.44,-4.48,;.89,-5.25,;2.23,-4.48,;2.23,-2.94,;.89,-2.17,;-.44,-1.4,;-.44,.14,;-4.44,-.63,)| Show InChI InChI=1S/C27H37ClN6O2/c1-19(16-35-2)32-20-6-8-21(9-7-20)33-26-14-22(23(28)15-30-26)24-4-3-5-25(34-24)31-18-27(17-29)10-12-36-13-11-27/h3-5,14-15,19-21,32H,6-13,16,18H2,1-2H3,(H,30,33)(H,31,34)/t19-,20-,21-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars		n/a	n/a	605	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Effective concentration required for inhibitory activity towards human beta-1 adrenergic receptor				Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 16 (Homo sapiens (Human))	BDBM50404389 (CHEMBL5285499) Show SMILES COCCN(CC(O)=O)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2cc3OCCOc3cc2c1 Show InChI InChI=1S/C23H31N5O8S/c1-34-8-7-28(14-21(29)30)22(31)18(3-2-6-26-23(24)25)27-37(32,33)17-5-4-15-12-19-20(13-16(15)11-17)36-10-9-35-19/h4-5,11-13,18,27H,2-3,6-10,14H2,1H3,(H,29,30)(H4,24,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	>1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of specifically bound [3H]naloxone from rat brain homogenate, in the absence of NaCl				Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 16 (Homo sapiens (Human))	BDBM50593922 (CHEMBL5199065) Show SMILES CCC(CC)c1cc(N[C@H]2CC[C@H](N)C2)n2nccc2n1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem		n/a	n/a	>1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of specifically bound [3H]naloxone from rat brain homogenate, in the absence of NaCl				Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 16 (Homo sapiens (Human))	BDBM186184 (US9163013, 1) Show SMILES COc1ccc2[nH]nc(C(=O)NCC3CCN(CCc4ccc(O)cc4)CC3)c2c1 Show InChI InChI=1S/C23H28N4O3/c1-30-19-6-7-21-20(14-19)22(26-25-21)23(29)24-15-17-9-12-27(13-10-17)11-8-16-2-4-18(28)5-3-16/h2-7,14,17,28H,8-13,15H2,1H3,(H,24,29)(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	22
AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. US Patent					Assay Description Compound 1 was also assayed to determine the IC50 values for three different kinases (PCTAIRE1, DYRK1a, and CDK2) in comparison to Gsk3beta. The ass...				US Patent US9163013 (2015) BindingDB Entry DOI: 10.7270/Q2PN94DT
					More data for this Ligand-Target Pair