Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Complement factor B [470-764] (Homo sapiens (Human)) | BDBM203865 (Methyl (S)-2-((2-((3-(trifluoromethoxy)phenyl)carb...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 7.4 | 4 |
Novartis Pharma AG | Assay Description Human CVF-Bb complex (3 nM concentration) was incubated with compound at various concentrations for 1 h at room temperature in PBS at pH 7.4, conta... | Nat Chem Biol 12: 1105-1110 (2016) Article DOI: 10.1038/nchembio.2208 BindingDB Entry DOI: 10.7270/Q2KD1WR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Complement factor B [470-764] (Homo sapiens (Human)) | BDBM171272 (1-(2-((1R,3S,5R)-3-(((R)-1-(3-Chloro-2-fluoropheny...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 7.4 | 4 |
Novartis Pharma AG | Assay Description Human CVF-Bb complex (3 nM concentration) was incubated with compound at various concentrations for 1 h at room temperature in PBS at pH 7.4, conta... | Nat Chem Biol 12: 1105-1110 (2016) Article DOI: 10.1038/nchembio.2208 BindingDB Entry DOI: 10.7270/Q2KD1WR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Complement factor B [470-764] (Homo sapiens (Human)) | BDBM203868 ((S)-N2-benzhydryl-N1-(1-methyl-1H-indol-3-yl)pyrro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 7.4 | 4 |
Novartis Pharma AG | Assay Description Human CVF-Bb complex (3 nM concentration) was incubated with compound at various concentrations for 1 h at room temperature in PBS at pH 7.4, conta... | Nat Chem Biol 12: 1105-1110 (2016) Article DOI: 10.1038/nchembio.2208 BindingDB Entry DOI: 10.7270/Q2KD1WR1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Complement factor B [470-764] (Homo sapiens (Human)) | BDBM203867 (3-(((2-Carbamoyl-1H-indol-5-yl)oxy)methyl)benzoic ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 7.4 | 4 |
Novartis Pharma AG | Assay Description Human CVF-Bb complex (3 nM concentration) was incubated with compound at various concentrations for 1 h at room temperature in PBS at pH 7.4, conta... | Nat Chem Biol 12: 1105-1110 (2016) Article DOI: 10.1038/nchembio.2208 BindingDB Entry DOI: 10.7270/Q2KD1WR1 | |||||||||||
More data for this Ligand-Target Pair |