Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM50515036 (CHEMBL4584267) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a |
Sun Yat-sen University Curated by ChEMBL | Assay Description Binding affinity to recombinant human LXRbeta-LBD expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant incubated for 30 mins by... | Eur J Med Chem 178: 458-467 (2019) Article DOI: 10.1016/j.ejmech.2019.06.011 BindingDB Entry DOI: 10.7270/Q2BC42WH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM50515025 (CHEMBL4464514) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 92 | n/a | n/a | n/a | n/a | n/a |
Sun Yat-sen University Curated by ChEMBL | Assay Description Binding affinity to recombinant human LXRbeta-LBD expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant incubated for 30 mins by... | Eur J Med Chem 178: 458-467 (2019) Article DOI: 10.1016/j.ejmech.2019.06.011 BindingDB Entry DOI: 10.7270/Q2BC42WH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM19993 (CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 103 | n/a | n/a | n/a | n/a | n/a |
Korea University Curated by ChEMBL | Assay Description Binding affinity to human LXRbeta-LBD by surface plasmon resonance | Bioorg Med Chem Lett 23: 4185-90 (2013) Article DOI: 10.1016/j.bmcl.2013.05.030 BindingDB Entry DOI: 10.7270/Q2NK3GF4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM50461063 (CHEMBL4226803 | US10457637, Compound 8) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
Nestle Skin Health Curated by ChEMBL | Assay Description Activity at LXRbeta (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused to the LXRbeta li... | Bioorg Med Chem Lett 28: 1269-1273 (2018) Article DOI: 10.1016/j.bmcl.2018.03.041 BindingDB Entry DOI: 10.7270/Q2WD437Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM50203462 (CHEMBL3931161) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
Galderma R&D Curated by ChEMBL | Assay Description Activity at GAL4 DBD-fused LXRbeta LBD (unknown origin) expressed in human HG5LN cells after 18 hrs by luciferase reporter gene assay | Bioorg Med Chem Lett 26: 5802-5808 (2016) Article DOI: 10.1016/j.bmcl.2016.10.023 BindingDB Entry DOI: 10.7270/Q2D79DDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM50241503 (2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-1-Benzopy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 7.32E+4 | n/a | n/a | n/a | n/a | n/a |
Korea University Curated by ChEMBL | Assay Description Binding affinity to human LXRbeta-LBD by surface plasmon resonance | Bioorg Med Chem Lett 23: 4185-90 (2013) Article DOI: 10.1016/j.bmcl.2013.05.030 BindingDB Entry DOI: 10.7270/Q2NK3GF4 | |||||||||||
More data for this Ligand-Target Pair |