Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein phosphatase non-receptor type 1 [1-301] (Homo sapiens (Human)) | BDBM50327036 ((1R,3S,4S,5S)-3-[(E)-3-(3,4-Dihydroxy-phenyl)-acry...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.50E+6 | n/a | n/a | n/a | n/a | n/a |
Washington College | Assay Description NMR chemical shift perturbations of PTP1B resonances due to binding of CHA and CGA were monitored by acquiring a series of 1H−15N TROSY spectra... | Biochemistry 56: 96-106 (2017) Article DOI: 10.1021/acs.biochem.6b01025 BindingDB Entry DOI: 10.7270/Q2JW8CQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 1 [1-301] (Homo sapiens (Human)) | BDBM50076273 ((2R,3R)-2,3-Bis-[(E)-3-(3,4-dihydroxy-phenyl)-acry...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.60E+6 | n/a | n/a | n/a | n/a | n/a |
Washington College | Assay Description NMR chemical shift perturbations of PTP1B resonances due to binding of CHA and CGA were monitored by acquiring a series of 1H−15N TROSY spectra... | Biochemistry 56: 96-106 (2017) Article DOI: 10.1021/acs.biochem.6b01025 BindingDB Entry DOI: 10.7270/Q2JW8CQJ | |||||||||||
More data for this Ligand-Target Pair |