BindingDB PrimarySearch

Found 20 hits of kd for UniProtKB: Q93009
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50465231 (CHEMBL4288150 \| US10766903, Example 30) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to USP7 (208 to 560 residues) (unknown origin) assessed as dissociation constant by biolayer interferometry				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112279 BindingDB Entry DOI: 10.7270/Q2KK9GFS
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50465231 (CHEMBL4288150 \| US10766903, Example 30) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01444 BindingDB Entry DOI: 10.7270/Q2WW7NR1
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50552092 (CHEMBL4762640) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to USP7 (208 to 560 residues) (unknown origin) assessed as dissociation constant by biolayer interferometry				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112279 BindingDB Entry DOI: 10.7270/Q2KK9GFS
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50602280 (CHEMBL5180062) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01444 BindingDB Entry DOI: 10.7270/Q2WW7NR1
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50602285 (CHEMBL5182862) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01444 BindingDB Entry DOI: 10.7270/Q2WW7NR1
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50602291 (CHEMBL5200808) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01444 BindingDB Entry DOI: 10.7270/Q2WW7NR1
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50602268 (CHEMBL5169772) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	128	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01444 BindingDB Entry DOI: 10.7270/Q2WW7NR1
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50602284 (CHEMBL4803149) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	148	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01444 BindingDB Entry DOI: 10.7270/Q2WW7NR1
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50602301 (CHEMBL5186229) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	541	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01444 BindingDB Entry DOI: 10.7270/Q2WW7NR1
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50602293 (CHEMBL5171419) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	675	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01444 BindingDB Entry DOI: 10.7270/Q2WW7NR1
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50608416 (CHEMBL5269448) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50250953 (CHEMBL4097744) Show SMILES Oc1ccc(cc1)-c1nc(no1)C1CCNCC1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Binding affinity to human His-tagged and [15N-13C-2H], delta1[13CH3]-Ile, [13CH3]-Leu/Val and [13CH3]-Met-labeled USP7-catalytic domain (208 to 554 r...				J Med Chem 60: 10056-10070 (2017) Article DOI: 10.1021/acs.jmedchem.7b01293 BindingDB Entry DOI: 10.7270/Q2QV3PX8
Genentech Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50250965 (CHEMBL4069137) Show SMILES CN1CCC(CC1)c1noc(n1)-c1ccc(O)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Binding affinity to human His-tagged and [15N-13C-2H], delta1[13CH3]-Ile, [13CH3]-Leu/Val and [13CH3]-Met-labeled USP7-catalytic domain (208 to 554 r...				J Med Chem 60: 10056-10070 (2017) Article DOI: 10.1021/acs.jmedchem.7b01293 BindingDB Entry DOI: 10.7270/Q2QV3PX8
Genentech Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50567580 (CHEMBL4845880) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	7.70E+4	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to recombinant USP7 (208 to 560 residues) (unknown origin) assessed as dissociation constant by biolayer interferometry				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113291 BindingDB Entry DOI: 10.7270/Q2QZ2FRS
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50465214 (CHEMBL4286062) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	4.71E+5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50465215 (CHEMBL2432028) Show SMILES O=c1[nH]cnc2sccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	4.71E+5	n/a	n/a	n/a	n/a	n/a
Almac Discovery Ltd. Curated by ChEMBL					Assay Description Binding affinity to recombinant human N-terminal His6-tagged USP7 catalytic domain (213 to 548 residues) expressed in baculovirus infected Sf21 insec...				ACS Med Chem Lett 9: 238-243 (2018) Article DOI: 10.1021/acsmedchemlett.7b00512 BindingDB Entry DOI: 10.7270/Q2Q81GRX
Almac Discovery Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50465231 (CHEMBL4288150 \| US10766903, Example 30) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem		n/a	n/a	n/a	4.71E+5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50560581 (CHEMBL4792948) Show SMILES CC(=O)Nc1nc2ccccn2c1-c1ccc(O)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	5.40E+5	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to USP7 (unknown origin) by T2 relaxation experiment based analysis				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127471 BindingDB Entry DOI: 10.7270/Q20P13R0
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50560581 (CHEMBL4792948) Show SMILES CC(=O)Nc1nc2ccccn2c1-c1ccc(O)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	5.80E+5	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Allosteric binding affinity to USP7 catalytic domain (unknown origin) at Met328 residues by NMR-15N-1H TROSY spectral titration analysis				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127471 BindingDB Entry DOI: 10.7270/Q20P13R0
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50560581 (CHEMBL4792948) Show SMILES CC(=O)Nc1nc2ccccn2c1-c1ccc(O)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	6.80E+5	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Allosteric binding affinity to USP7 catalytic domain (unknown origin) at Met328, Trp285, Gly284, Gln405 and Gly313 residues by NMR-15N-1H TROSY spect...				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127471 BindingDB Entry DOI: 10.7270/Q20P13R0
TBA					More data for this Ligand-Target Pair