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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for UniProtKB: P19174   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1


(Homo sapiens (Human))		BDBM50535744
PNG
(CHEMBL4536333)
Show SMILES [H][C@]12CS[C@@H](CCCCC(=O)N[C@@H]([C@@H](C)O)C(=O)NCCN([C@@H](CCCNC(N)=N)C(=O)NCCN([C@@H](Cc3c[nH]cn3)C(=O)NCCN([C@@H](CCCCN)C(N)=O)C(=O)CCCCNC(N)=N)C(=O)CCCCCN)C(=O)CCS)[C@@]1([H])NC(=O)N2 |r|
Show InChI InChI=1S/C53H96N20O10S2/c1-34(74)45(69-41(75)15-5-4-14-40-46-36(32-85-40)68-53(83)70-46)50(82)64-25-27-72(44(78)18-29-84)38(13-11-22-66-52(59)60)48(80)62-24-28-73(43(77)16-3-2-8-19-54)39(30-35-31-61-33-67-35)49(81)63-23-26-71(37(47(56)79)12-6-9-20-55)42(76)17-7-10-21-65-51(57)58/h31,33-34,36-40,45-46,74,84H,2-30,32,54-55H2,1H3,(H2,56,79)(H,61,67)(H,62,80)(H,63,81)(H,64,82)(H,69,75)(H4,57,58,65)(H4,59,60,66)(H2,68,70,83)/t34-,36+,37+,38+,39+,40+,45+,46+/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 2.50E+4n/an/an/an/a



CLCC Eug�ne Marquis, INSERM, Univ Rennes 1, UMR1242, rue Bataille Flandres Dunkerque, 35042 Rennes, France; Equipe Ligue Contre Le Cancer, rue Bataille Flandres Dunkerque, 35042 Rennes, France.

Curated by ChEMBL


Assay Description
Binding affinity to human full length Myc-tagged PLCgamma1 transfected in HEK293T cells by pull down assay

Bioorg Med Chem Lett 29: 2094-2099 (2019)


Article DOI: 10.1016/j.bmcl.2019.07.006
BindingDB Entry DOI: 10.7270/Q24171KW
More data for this
Ligand-Target Pair