Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Amyloid-beta precursor protein [1-42] (Homo sapiens (Human)) | BDBM50492518 (Florbetapir | US10906900, AV45) | MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent | Assay Description Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese... | US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amyloid-beta precursor protein [1-42] (Homo sapiens (Human)) | BDBM50185987 (2-(1-(6-((2-fluoroethyl)(methyl)amino)naphthalen-2...) | MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | US Patent | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent | Assay Description Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese... | US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amyloid-beta precursor protein [1-42] (Homo sapiens (Human)) | BDBM481151 (US10906900, Reference 22c) | MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 21.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent | Assay Description Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese... | US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amyloid-beta precursor protein [1-42] (Homo sapiens (Human)) | BDBM481149 (US10906900, Reference 22a) | MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 24.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent | Assay Description Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese... | US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amyloid-beta precursor protein [1-42] (Homo sapiens (Human)) | BDBM481150 (US10906900, Reference 22b) | MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 91.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent | Assay Description Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese... | US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amyloid-beta precursor protein [1-42] (Homo sapiens (Human)) | BDBM481155 (US10906900, Reference 22h) | MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 244 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent | Assay Description Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese... | US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amyloid-beta precursor protein [1-42] (Homo sapiens (Human)) | BDBM481154 (US10906900, Reference 22g) | MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 318 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent | Assay Description Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese... | US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amyloid-beta precursor protein [1-42] (Homo sapiens (Human)) | BDBM481153 (US10906900, Reference 22f) | MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 349 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent | Assay Description Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese... | US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amyloid-beta precursor protein [1-42] (Homo sapiens (Human)) | BDBM481152 (US10906900, Reference 22e) | MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 909 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent | Assay Description Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese... | US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC | |||||||||||
More data for this Ligand-Target Pair |