Compile Data Set for Download or QSAR

Found 347 hits Enz. Inhib. hit(s) with all data for entry = 10904   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825] (Homo sapiens (Human))	BDBM577094 ((7S)-10-(4-Chlorophenyl)-8-cyclopropyl-7-methyl-7,...) Show SMILES C[C@H]1Cn2c(c(-c3ccc(Cl)cc3)c3ncccc23)C(=O)N1C1CC1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825] (Homo sapiens (Human))	BDBM577172 (10-(4-Chloro-3-fluorophenyl)-8-cyclopropyl-3,4,7,8...) Show SMILES Fc1cc(ccc1Cl)-c1c2OCCCc2n2CCN(C3CC3)C(=O)c12 Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.310	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825] (Homo sapiens (Human))	BDBM577135 (8-Cyclopropyl-10-(3,4,5-trifluorophenyl)-7,8-dihyd...) Show SMILES Fc1cc(cc(F)c1F)-c1c2C(=O)N(CCn2c2cccnc12)C1CC1 Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.410	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736] (Homo sapiens (Human))	BDBM577077 (10-(4-Chlorophenyl)-8-cyclopropyl-7,8-dihydropyrid...) Show SMILES Clc1ccc(cc1)-c1c2C(=O)N(CCn2c2cccnc12)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.420	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825] (Homo sapiens (Human))	BDBM577126 (10-(4-Chloro-3-fluorophenyl)-8-cyclopropyl-7,8-dih...) Show SMILES Fc1cc(ccc1Cl)-c1c2C(=O)N(CCn2c2cccnc12)C1CC1 Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.450	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736] (Homo sapiens (Human))	BDBM577094 ((7S)-10-(4-Chlorophenyl)-8-cyclopropyl-7-methyl-7,...) Show SMILES C[C@H]1Cn2c(c(-c3ccc(Cl)cc3)c3ncccc23)C(=O)N1C1CC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.520	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736] (Homo sapiens (Human))	BDBM577172 (10-(4-Chloro-3-fluorophenyl)-8-cyclopropyl-3,4,7,8...) Show SMILES Fc1cc(ccc1Cl)-c1c2OCCCc2n2CCN(C3CC3)C(=O)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.550	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4C [2-712] ()	BDBM577094 ((7S)-10-(4-Chlorophenyl)-8-cyclopropyl-7-methyl-7,...) Show SMILES C[C@H]1Cn2c(c(-c3ccc(Cl)cc3)c3ncccc23)C(=O)N1C1CC1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.570	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736] (Homo sapiens (Human))	BDBM577128 (2-Chloro-5-(8-cyclopropyl-9-oxo-6,7,8,9-tetrahydro...) Show SMILES Clc1ccc(cc1C#N)-c1c2C(=O)N(CCn2c2cccnc12)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.640	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825] (Homo sapiens (Human))	BDBM577130 (10-(3-Chloro-4-fluorophenyl)-8-cyclopropyl-7,8-dih...) Show SMILES Fc1ccc(cc1Cl)-c1c2C(=O)N(CCn2c2cccnc12)C1CC1 Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.670	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736] (Homo sapiens (Human))	BDBM577135 (8-Cyclopropyl-10-(3,4,5-trifluorophenyl)-7,8-dihyd...) Show SMILES Fc1cc(cc(F)c1F)-c1c2C(=O)N(CCn2c2cccnc12)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.670	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736] (Homo sapiens (Human))	BDBM577126 (10-(4-Chloro-3-fluorophenyl)-8-cyclopropyl-7,8-dih...) Show SMILES Fc1cc(ccc1Cl)-c1c2C(=O)N(CCn2c2cccnc12)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736] (Homo sapiens (Human))	BDBM577143 (10-(3-Chlorophenyl)-8-cyclopropyl-7,8-dihydropyrid...) Show SMILES Clc1cccc(c1)-c1c2C(=O)N(CCn2c2cccnc12)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.720	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736] (Homo sapiens (Human))	BDBM577079 (4-(8-Cyclopropyl-9-oxo-6,7,8,9-tetrahydropyrido[2&...) Show SMILES Fc1cc(ccc1C#N)-c1c2C(=O)N(CCn2c2cccnc12)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	<0.810	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736] (Homo sapiens (Human))	BDBM577173 (10-(4-Chloro-2,5-difluorophenyl)-8-cyclopropyl-3,4...) Show SMILES Fc1cc(-c2c3OCCCc3n3CCN(C4CC4)C(=O)c23)c(F)cc1Cl |(3.02,2.67,;1.51,2.35,;1.04,.89,;-.47,.57,;-.94,-.9,;-2.41,-1.38,;-3.74,-.61,;-5.08,-1.38,;-5.08,-2.92,;-3.74,-3.69,;-2.41,-2.92,;-.94,-3.39,;-.32,-4.8,;1.21,-4.96,;2.12,-3.71,;3.65,-3.87,;4.87,-4.82,;5.08,-3.29,;1.49,-2.31,;2.4,-1.06,;-.04,-2.15,;-1.5,1.71,;-3,1.39,;-1.02,3.17,;.48,3.49,;.96,4.96,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.840	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825] (Homo sapiens (Human))	BDBM577128 (2-Chloro-5-(8-cyclopropyl-9-oxo-6,7,8,9-tetrahydro...) Show SMILES Clc1ccc(cc1C#N)-c1c2C(=O)N(CCn2c2cccnc12)C1CC1 Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.980	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825] (Homo sapiens (Human))	BDBM577077 (10-(4-Chlorophenyl)-8-cyclopropyl-7,8-dihydropyrid...) Show SMILES Clc1ccc(cc1)-c1c2C(=O)N(CCn2c2cccnc12)C1CC1 Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.990	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825] (Homo sapiens (Human))	BDBM577173 (10-(4-Chloro-2,5-difluorophenyl)-8-cyclopropyl-3,4...) Show SMILES Fc1cc(-c2c3OCCCc3n3CCN(C4CC4)C(=O)c23)c(F)cc1Cl |(3.02,2.67,;1.51,2.35,;1.04,.89,;-.47,.57,;-.94,-.9,;-2.41,-1.38,;-3.74,-.61,;-5.08,-1.38,;-5.08,-2.92,;-3.74,-3.69,;-2.41,-2.92,;-.94,-3.39,;-.32,-4.8,;1.21,-4.96,;2.12,-3.71,;3.65,-3.87,;4.87,-4.82,;5.08,-3.29,;1.49,-2.31,;2.4,-1.06,;-.04,-2.15,;-1.5,1.71,;-3,1.39,;-1.02,3.17,;.48,3.49,;.96,4.96,)| Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825] (Homo sapiens (Human))	BDBM577123 (10-(4-Chloro-5-fluoro-2-methylphenyl)-8-cyclopropy...) Show SMILES Cc1cc(Cl)c(F)cc1-c1c2OCCCc2n2CCN(C3CC3)C(=O)c12 |(-3.15,.66,;-1.65,.98,;-1.17,2.44,;.35,2.81,;.83,4.28,;1.37,1.62,;2.87,1.94,;.89,.15,;-.62,-.17,;-1.09,-1.63,;-2.56,-2.11,;-3.89,-1.34,;-5.22,-2.11,;-5.22,-3.65,;-3.89,-4.42,;-2.56,-3.65,;-1.09,-4.12,;-.47,-5.53,;1.07,-5.69,;1.97,-4.45,;3.5,-4.61,;4.72,-5.55,;4.93,-4.02,;1.34,-3.04,;2.25,-1.79,;-.19,-2.88,)| Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736] (Homo sapiens (Human))	BDBM577123 (10-(4-Chloro-5-fluoro-2-methylphenyl)-8-cyclopropy...) Show SMILES Cc1cc(Cl)c(F)cc1-c1c2OCCCc2n2CCN(C3CC3)C(=O)c12 |(-3.15,.66,;-1.65,.98,;-1.17,2.44,;.35,2.81,;.83,4.28,;1.37,1.62,;2.87,1.94,;.89,.15,;-.62,-.17,;-1.09,-1.63,;-2.56,-2.11,;-3.89,-1.34,;-5.22,-2.11,;-5.22,-3.65,;-3.89,-4.42,;-2.56,-3.65,;-1.09,-4.12,;-.47,-5.53,;1.07,-5.69,;1.97,-4.45,;3.5,-4.61,;4.72,-5.55,;4.93,-4.02,;1.34,-3.04,;2.25,-1.79,;-.19,-2.88,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736] (Homo sapiens (Human))	BDBM577102 (10-(4-Chlorophenyl)-8-propyl-7,8-dihydropyrido[2',...) Show SMILES CCCN1CCn2c(c(-c3ccc(Cl)cc3)c3ncccc23)C1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825] (Homo sapiens (Human))	BDBM577143 (10-(3-Chlorophenyl)-8-cyclopropyl-7,8-dihydropyrid...) Show SMILES Clc1cccc(c1)-c1c2C(=O)N(CCn2c2cccnc12)C1CC1 Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736] (Homo sapiens (Human))	BDBM577130 (10-(3-Chloro-4-fluorophenyl)-8-cyclopropyl-7,8-dih...) Show SMILES Fc1ccc(cc1Cl)-c1c2C(=O)N(CCn2c2cccnc12)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736] (Homo sapiens (Human))	BDBM577142 (10-(4-Chloro-2-fluorophenyl)-8-cyclopropyl-7,8-dih...) Show SMILES Fc1cc(Cl)ccc1-c1c2C(=O)N(CCn2c2cccnc12)C1CC1 |(-3,1.39,;-1.5,1.71,;-1.02,3.17,;.48,3.49,;.96,4.96,;1.51,2.35,;1.04,.89,;-.47,.57,;-.94,-.9,;-.04,-2.15,;1.49,-2.31,;2.4,-1.06,;2.12,-3.71,;1.21,-4.96,;-.32,-4.8,;-.94,-3.39,;-2.41,-2.92,;-3.74,-3.69,;-5.08,-2.92,;-5.08,-1.38,;-3.74,-.61,;-2.41,-1.38,;3.65,-3.87,;4.87,-4.82,;5.08,-3.29,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825] (Homo sapiens (Human))	BDBM577091 (10-(4-Chloro-3-fluorophenyl)-8-cyclopropyl-7,8-dih...) Show SMILES Fc1cc(ccc1Cl)-c1c2C(=O)N(CCn2c2nccnc12)C1CC1 Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.19	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825] (Homo sapiens (Human))	BDBM577171 (10-(4-Chlorophenyl)-8-cyclopropyl-3,4,7,8-tetrahyd...) Show SMILES Clc1ccc(cc1)-c1c2OCCCc2n2CCN(C3CC3)C(=O)c12 Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.26	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825] (Homo sapiens (Human))	BDBM577136 (8-Cyclopropyl-10-(3-fluorophenyl)-7,8-dihydropyrid...) Show SMILES Fc1cccc(c1)-c1c2C(=O)N(CCn2c2cccnc12)C1CC1 Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.26	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736] (Homo sapiens (Human))	BDBM577091 (10-(4-Chloro-3-fluorophenyl)-8-cyclopropyl-7,8-dih...) Show SMILES Fc1cc(ccc1Cl)-c1c2C(=O)N(CCn2c2nccnc12)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.27	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736] (Homo sapiens (Human))	BDBM577078 ((6aR)-12-(4-Chlorophenyl)-6a, 7,8,9-tetrahydro-6H,...) Show SMILES Clc1ccc(cc1)-c1c2C(=O)N3CCC[C@@H]3Cn2c2cccnc12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.38	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4C [2-712] ()	BDBM577126 (10-(4-Chloro-3-fluorophenyl)-8-cyclopropyl-7,8-dih...) Show SMILES Fc1cc(ccc1Cl)-c1c2C(=O)N(CCn2c2cccnc12)C1CC1 Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.44	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825] (Homo sapiens (Human))	BDBM577101 (4-(8-Cyclopropyl-9-oxo-3,4,6,7,8,9-hexahydro-2H-py...) Show SMILES Cc1cc(C#N)c(F)cc1-c1c2OCCCc2n2CCN(C3CC3)C(=O)c12 |(16.64,-5.82,;18.13,-5.42,;18.53,-3.94,;20.03,-3.48,;20.43,-2,;20.83,-.51,;21.1,-4.63,;22.59,-4.23,;20.7,-6.11,;19.22,-6.51,;18.82,-8,;17.35,-8.48,;16.02,-7.71,;14.69,-8.48,;14.69,-10.02,;16.02,-10.79,;17.35,-10.02,;18.82,-10.49,;19.45,-11.9,;20.98,-12.06,;21.88,-10.81,;23.37,-11.21,;24.46,-12.3,;24.86,-10.81,;21.26,-9.41,;22.03,-8.07,;19.72,-9.25,)| Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.57	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825] (Homo sapiens (Human))	BDBM577140 (8-Cyclopropyl-10-(3-fluoro-4-methoxyphenyl)-7,8-di...) Show SMILES COc1ccc(cc1F)-c1c2C(=O)N(CCn2c2cccnc12)C1CC1 Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.59	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736] (Homo sapiens (Human))	BDBM577101 (4-(8-Cyclopropyl-9-oxo-3,4,6,7,8,9-hexahydro-2H-py...) Show SMILES Cc1cc(C#N)c(F)cc1-c1c2OCCCc2n2CCN(C3CC3)C(=O)c12 |(16.64,-5.82,;18.13,-5.42,;18.53,-3.94,;20.03,-3.48,;20.43,-2,;20.83,-.51,;21.1,-4.63,;22.59,-4.23,;20.7,-6.11,;19.22,-6.51,;18.82,-8,;17.35,-8.48,;16.02,-7.71,;14.69,-8.48,;14.69,-10.02,;16.02,-10.79,;17.35,-10.02,;18.82,-10.49,;19.45,-11.9,;20.98,-12.06,;21.88,-10.81,;23.37,-11.21,;24.46,-12.3,;24.86,-10.81,;21.26,-9.41,;22.03,-8.07,;19.72,-9.25,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.78	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825] (Homo sapiens (Human))	BDBM577096 (8-Cyclopropyl-10-(4-methylphenyl)pyrido[2′,3...) Show SMILES Cc1ccc(cc1)-c1c2ncccc2n2ccn(C3CC3)c(=O)c12 Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.86	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825] (Homo sapiens (Human))	BDBM577142 (10-(4-Chloro-2-fluorophenyl)-8-cyclopropyl-7,8-dih...) Show SMILES Fc1cc(Cl)ccc1-c1c2C(=O)N(CCn2c2cccnc12)C1CC1 |(-3,1.39,;-1.5,1.71,;-1.02,3.17,;.48,3.49,;.96,4.96,;1.51,2.35,;1.04,.89,;-.47,.57,;-.94,-.9,;-.04,-2.15,;1.49,-2.31,;2.4,-1.06,;2.12,-3.71,;1.21,-4.96,;-.32,-4.8,;-.94,-3.39,;-2.41,-2.92,;-3.74,-3.69,;-5.08,-2.92,;-5.08,-1.38,;-3.74,-.61,;-2.41,-1.38,;3.65,-3.87,;4.87,-4.82,;5.08,-3.29,)| Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4C [2-712] ()	BDBM577172 (10-(4-Chloro-3-fluorophenyl)-8-cyclopropyl-3,4,7,8...) Show SMILES Fc1cc(ccc1Cl)-c1c2OCCCc2n2CCN(C3CC3)C(=O)c12 Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825] (Homo sapiens (Human))	BDBM577129 (8-Cyclopropyl-10-(2,3-dihydro-1-benzofuran-5-yl)-7...) Show SMILES O=C1N(CCn2c1c(-c1ccc3OCCc3c1)c1ncccc21)C1CC1 Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.08	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736] (Homo sapiens (Human))	BDBM577122 (4-(7-Cyclopropyl-8-oxo-5,6,7,8-tetrahydro[1,3]thia...) Show SMILES Cc1cc(C#N)c(F)cc1-c1c2C(=O)N(CCn2c2scnc12)C1CC1 |(-3.15,.66,;-1.65,.98,;-1.17,2.44,;.35,2.81,;.83,4.28,;1.3,5.74,;1.37,1.62,;2.87,1.94,;.89,.15,;-.62,-.17,;-1.09,-1.63,;-.19,-2.88,;1.34,-3.04,;2.25,-1.79,;1.97,-4.45,;1.07,-5.69,;-.47,-5.53,;-1.09,-4.12,;-2.56,-3.65,;-4.02,-4.12,;-4.93,-2.88,;-4.02,-1.63,;-2.56,-2.11,;3.5,-4.61,;4.72,-5.55,;4.93,-4.02,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825] (Homo sapiens (Human))	BDBM577121 (9-(4-Chlorophenyl)-7-cyclopropyl-6,7-dihydro[1,3]t...) Show SMILES Clc1ccc(cc1)-c1c2C(=O)N(CCn2c2scnc12)C1CC1 Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.28	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825] (Homo sapiens (Human))	BDBM577141 (8-Cyclopropyl-10-(2,5-difluorophenyl)-7,8-dihydrop...) Show SMILES Fc1ccc(F)c(c1)-c1c2C(=O)N(CCn2c2cccnc12)C1CC1 |(3.02,3.4,;1.51,3.08,;.48,4.23,;-1.02,3.91,;-1.5,2.44,;-3,2.12,;-.47,1.3,;1.04,1.62,;-.94,-.17,;-.04,-1.41,;1.49,-1.57,;2.4,-.33,;2.12,-2.98,;1.21,-4.23,;-.32,-4.07,;-.94,-2.66,;-2.41,-2.18,;-3.74,-2.95,;-5.08,-2.18,;-5.08,-.64,;-3.74,.13,;-2.41,-.64,;3.65,-3.14,;4.87,-4.08,;5.08,-2.56,)| Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.29	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736] (Homo sapiens (Human))	BDBM577136 (8-Cyclopropyl-10-(3-fluorophenyl)-7,8-dihydropyrid...) Show SMILES Fc1cccc(c1)-c1c2C(=O)N(CCn2c2cccnc12)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.38	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736] (Homo sapiens (Human))	BDBM577125 (10-(4-Chlorophenyl)-8-ethyl-7,8-dihydropyrido[2',3...) Show SMILES CCN1CCn2c(c(-c3ccc(Cl)cc3)c3ncccc23)C1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.43	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4C [2-712] ()	BDBM577123 (10-(4-Chloro-5-fluoro-2-methylphenyl)-8-cyclopropy...) Show SMILES Cc1cc(Cl)c(F)cc1-c1c2OCCCc2n2CCN(C3CC3)C(=O)c12 |(-3.15,.66,;-1.65,.98,;-1.17,2.44,;.35,2.81,;.83,4.28,;1.37,1.62,;2.87,1.94,;.89,.15,;-.62,-.17,;-1.09,-1.63,;-2.56,-2.11,;-3.89,-1.34,;-5.22,-2.11,;-5.22,-3.65,;-3.89,-4.42,;-2.56,-3.65,;-1.09,-4.12,;-.47,-5.53,;1.07,-5.69,;1.97,-4.45,;3.5,-4.61,;4.72,-5.55,;4.93,-4.02,;1.34,-3.04,;2.25,-1.79,;-.19,-2.88,)| Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.45	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825] (Homo sapiens (Human))	BDBM577182 (10-Cyclopentyl-8-cyclopropyl-7,8-dihydropyrido[2',...) Show SMILES O=C1N(CCn2c1c(C1CCCC1)c1ncccc21)C1CC1 Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.52	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825] (Homo sapiens (Human))	BDBM577131 (8-Cyclopropyl-10-(4-fluoro-3-methylphenyl)-7,8-dih...) Show SMILES Cc1cc(ccc1F)-c1c2C(=O)N(CCn2c2cccnc12)C1CC1 Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.52	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825] (Homo sapiens (Human))	BDBM577107 (8-Cyclopropyl-10-(4-methylphenyl)-7,8-dihydropyrid...) Show SMILES Cc1ccc(cc1)-c1c2C(=O)N(CCn2c2cccnc12)C1CC1 Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.52	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736] (Homo sapiens (Human))	BDBM577090 (10-(4-Chloro-3-fluorophenyl)-8-cyclopropyl-7,8-dih...) Show SMILES Fc1cc(ccc1Cl)-c1c2C(=O)N(CCn2c2cncnc12)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.53	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736] (Homo sapiens (Human))	BDBM577182 (10-Cyclopentyl-8-cyclopropyl-7,8-dihydropyrido[2',...) Show SMILES O=C1N(CCn2c1c(C1CCCC1)c1ncccc21)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.63	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736] (Homo sapiens (Human))	BDBM577166 (4-(8-Cyclopropyl-9-oxo-8,9-dihydropyrido[2',3':4,5...) Show SMILES O=c1n(ccn2c3cccnc3c(-c3ccc(cc3)C#N)c12)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.67	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736] (Homo sapiens (Human))	BDBM577096 (8-Cyclopropyl-10-(4-methylphenyl)pyrido[2′,3...) Show SMILES Cc1ccc(cc1)-c1c2ncccc2n2ccn(C3CC3)c(=O)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4P16
					More data for this Ligand-Target Pair

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