Compile Data Set for Download or QSAR

Found 79 hits Enz. Inhib. hit(s) with all data for entry = 10969   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride lipase (Homo sapiens (Human))	BDBM581474 ((2s,4s)-2-(2-(3-(tert-Butyl)phenyl)-7-azaspiro[3.5...) Show SMILES CC(C)(C)c1cccc(c1)C1CC2(C1)CCN(CC2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2 |r,wU:21.23,wD:23.26,(9.82,-.16,;8.48,-.93,;8.48,.61,;9.82,-1.7,;7.15,-1.7,;7.15,-3.24,;5.82,-4.01,;4.48,-3.24,;4.48,-1.7,;5.82,-.93,;3.15,-.93,;1.66,-1.33,;1.26,.16,;2.75,.56,;-.07,-.61,;-1.41,.16,;-1.41,1.7,;-.07,2.47,;1.26,1.7,;-2.74,2.47,;-2.74,4.01,;-4.07,1.7,;-4.47,.21,;-5.96,.61,;-5.56,2.1,;-5.96,-.93,;-7.42,-1.41,;-8.33,-.16,;-9.82,.24,;-7.42,1.09,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0140	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581599 ((2r,4s)-2-(2-(5-(tert-Butyl)-2-methylphenyl)-7-aza...) Show SMILES Cc1ccc(cc1C1CC2(C1)CCN(CC2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2)C(C)(C)C |r,wU:18.20,wD:20.23,(3.21,-4.01,;4.54,-3.24,;5.88,-4.01,;7.21,-3.24,;7.21,-1.7,;5.88,-.93,;4.54,-1.7,;3.21,-.93,;1.72,-1.33,;1.32,.16,;2.81,.56,;-.01,-.61,;-1.35,.16,;-1.35,1.7,;-.01,2.47,;1.32,1.7,;-2.68,2.47,;-2.68,4.01,;-4.01,1.7,;-4.41,.21,;-5.9,.61,;-5.5,2.1,;-6.06,-.92,;-7.57,-1.24,;-8.34,.09,;-9.88,.09,;-7.31,1.24,;8.54,-.93,;9.88,-.16,;8.54,.61,;9.88,-1.7,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0270	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581624 ((rac)-(2s,4s)-2-(2-(4-(Trifluoromethyl)phenyl)-8-a...) Show SMILES FC(F)(F)c1ccc(cc1)C1CCC2(C1)CCN(CC2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2 |r,wU:22.24,wD:24.27,(10.43,.68,;9.09,-.09,;9.49,1.39,;10.43,-.86,;7.6,-.49,;7.21,-1.98,;5.72,-2.38,;4.63,-1.29,;5.03,.2,;6.52,.6,;3.14,-1.69,;2.24,-2.93,;.77,-2.46,;.77,-.92,;2.24,-.44,;-.56,-1.69,;-1.9,-.92,;-1.9,.62,;-.56,1.39,;.77,.62,;-3.23,1.39,;-3.23,2.93,;-4.56,.62,;-4.96,-.86,;-6.45,-.47,;-6.05,1.02,;-6.61,-2,;-8.12,-2.32,;-8.89,-.98,;-10.43,-.98,;-7.86,.16,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0390	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581534 ((2s,4s)-2-[2-(3-Isopropylphenyl)-7-azaspiro[3.5]no...) Show SMILES CC(C)c1cccc(c1)C1CC2(C1)CCN(CC2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2 |r,wU:20.22,wD:22.25,(9.82,-1.7,;8.48,-.93,;8.48,.61,;7.15,-1.7,;7.15,-3.24,;5.82,-4.01,;4.48,-3.24,;4.48,-1.7,;5.82,-.93,;3.15,-.93,;1.66,-1.33,;1.26,.16,;2.75,.56,;-.07,-.61,;-1.41,.16,;-1.41,1.7,;-.07,2.47,;1.26,1.7,;-2.74,2.47,;-2.74,4.01,;-4.07,1.7,;-4.47,.21,;-5.96,.61,;-5.56,2.1,;-5.96,-.93,;-7.42,-1.41,;-8.33,-.16,;-9.82,.24,;-7.42,1.09,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0410	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581597 ((2s,4s)-2-[2-(2,4-Dimethylphenyl)-7-azaspiro[3.5]n...) Show SMILES Cc1ccc(C2CC3(C2)CCN(CC3)C(=O)[C@H]2C[C@@]3(C2)COC(=O)N3)c(C)c1 |r,wU:16.17,wD:18.20,(9.15,-4.01,;7.82,-3.24,;7.82,-1.7,;6.48,-.93,;5.15,-1.7,;3.81,-.93,;2.33,-1.33,;1.93,.16,;3.42,.56,;.59,-.61,;-.74,.16,;-.74,1.7,;.59,2.47,;1.93,1.7,;-2.07,2.47,;-2.07,4.01,;-3.41,1.7,;-3.8,.21,;-5.29,.61,;-4.89,2.1,;-5.29,-.93,;-6.76,-1.41,;-7.66,-.16,;-9.15,.24,;-6.76,1.09,;5.15,-3.24,;3.81,-4.01,;6.48,-4.01,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0480	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581596 ((2r,4s)-2-(2-(3-(tert-Butyl)phenyl)-7-azaspiro[3.5...) Show SMILES CC(C)(C)c1cccc(c1)C1CC2(C1)CCN(CC2)C(=O)[C@H]1C[C@@]2(C1)CCC(=O)N2 |r,wU:21.23,wD:23.26,(9.82,-1.7,;8.48,-.93,;8.48,.61,;9.82,-.16,;7.15,-1.7,;7.15,-3.24,;5.82,-4.01,;4.48,-3.24,;4.48,-1.7,;5.82,-.93,;3.15,-.93,;1.66,-1.33,;1.26,.16,;2.75,.56,;-.07,-.61,;-1.41,.16,;-1.41,1.7,;-.07,2.47,;1.26,1.7,;-2.74,2.47,;-2.74,4.01,;-4.07,1.7,;-4.47,.21,;-5.96,.61,;-5.56,2.1,;-5.96,-.93,;-7.42,-1.41,;-8.33,-.16,;-9.82,.24,;-7.42,1.09,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0820	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581635 ((rac)-(2s,4s)-2-(6-(3-(tert-Butyl)phenyl)-2-azaspi...) Show SMILES CC(C)(C)c1cccc(c1)C1CCC2(CN(C2)C(=O)[C@H]2C[C@@]3(C2)COC(=O)N3)C1 |r,wU:19.20,wD:21.23,(9.51,-2.32,;8,-2.58,;7.46,-4.03,;8.98,-3.77,;7.01,-1.4,;7.55,.05,;6.56,1.23,;5.04,.97,;4.51,-.47,;5.49,-1.66,;2.97,-.47,;2.07,-1.72,;.6,-1.24,;.6,.3,;.36,1.82,;-1.16,1.58,;-.92,.06,;-2.41,2.49,;-2.41,4.03,;-3.81,1.86,;-4.21,.37,;-5.7,.77,;-5.3,2.26,;-5.62,-.77,;-7.06,-1.32,;-8.03,-.12,;-9.51,.08,;-7.19,1.17,;2.07,.78,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0860	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581518 ((2s,4s)-2-[2-(3-Cyclopropylphenyl)-7-azaspiro[3.5]...) Show SMILES O=C([C@H]1C[C@@]2(C1)COC(=O)N2)N1CCC2(CC(C2)c2cccc(c2)C2CC2)CC1 |r,wU:2.1,wD:4.4,(-2.84,4.01,;-2.84,2.47,;-4.18,1.7,;-4.57,.21,;-6.06,.61,;-5.66,2.1,;-6.06,-.93,;-7.53,-1.41,;-8.43,-.16,;-9.92,.24,;-7.53,1.09,;-1.51,1.7,;-1.51,.16,;-.18,-.61,;1.16,.16,;1.56,-1.33,;3.04,-.93,;2.65,.56,;4.38,-1.7,;4.38,-3.24,;5.71,-4.01,;7.05,-3.24,;7.05,-1.7,;5.71,-.93,;8.38,-.93,;9.92,-.93,;9.15,.4,;1.16,1.7,;-.18,2.47,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0880	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581594 ((2s,4s)-2-[2-[3-(Trifluoromethoxy)phenyl]-7-azaspi...) Show SMILES FC(F)(F)Oc1cccc(c1)C1CC2(C1)CCN(CC2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2 |r,wU:22.24,wD:24.27,(8.53,2.18,;8.53,.64,;10.07,.64,;6.99,.64,;8.53,-.9,;7.2,-1.67,;7.15,-3.24,;5.82,-4.01,;4.48,-3.24,;4.48,-1.7,;5.82,-.93,;3.15,-.93,;1.66,-1.33,;1.26,.16,;2.75,.56,;-.07,-.61,;-1.41,.16,;-1.41,1.7,;-.07,2.47,;1.26,1.7,;-2.74,2.47,;-2.74,4.01,;-4.07,1.7,;-4.47,.21,;-5.96,.61,;-5.56,2.1,;-5.96,-.93,;-7.42,-1.41,;-8.33,-.16,;-9.82,.24,;-7.42,1.09,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0940	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581601 ((2r,4s)-2-(2-(6-(tert-Butyl)pyridin-2-yl)-7-azaspi...) Show SMILES CC(C)(C)c1cccc(n1)C1CC2(C1)CCN(CC2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2 |r,wU:21.23,wD:23.26,(9.88,-.16,;8.54,-.93,;8.54,.61,;9.88,-1.7,;7.21,-1.7,;7.21,-3.24,;5.88,-4.01,;4.54,-3.24,;4.54,-1.7,;5.88,-.93,;3.21,-.93,;1.72,-1.33,;1.32,.16,;2.81,.56,;-.01,-.61,;-1.35,.16,;-1.35,1.7,;-.01,2.47,;1.32,1.7,;-2.68,2.47,;-2.68,4.01,;-4.01,1.7,;-4.41,.21,;-5.9,.61,;-5.5,2.1,;-6.06,-.92,;-7.57,-1.24,;-8.34,.09,;-9.88,.09,;-7.31,1.24,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0950	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581650 ((2s,4s)-2-(6-(3-(tert-Butyl)phenyl)-2-azaspiro[3.3...) Show SMILES CC(C)(C)c1cccc(c1)C1CC2(C1)CN(C2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2 |r,wU:19.21,wD:21.24,(8.07,.84,;8.07,-.7,;9.4,-1.47,;9.4,.07,;6.74,-1.47,;6.74,-3.01,;5.4,-3.78,;4.07,-3.01,;4.07,-1.47,;5.4,-.7,;2.74,-.7,;1.25,-1.1,;.85,.38,;2.34,.78,;-.64,-.01,;-1.04,1.47,;.45,1.87,;-2.37,2.24,;-2.37,3.78,;-3.7,1.47,;-4.1,-.01,;-5.59,.39,;-5.19,1.87,;-5.51,-1.15,;-6.95,-1.7,;-7.92,-.51,;-9.4,-.43,;-7.08,.78,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0970	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581631 ((2s,4R*)-2-((S*)-6-(4-(Trifluoromethyl)phenyl)-2-a...) Show SMILES FC(F)(F)c1ccc(cc1)[C@H]1CCC2(CN(C2)C(=O)[C@H]2C[C@@]3(C2)COC(=O)N3)C1 |r,wU:10.10,19.20,wD:21.23,(9.12,.44,;8.54,-.99,;9.48,-2.2,;10.06,-.77,;7.01,-1.2,;6.43,-2.63,;4.91,-2.84,;3.96,-1.62,;4.54,-.2,;6.07,.02,;2.42,-1.62,;1.52,-2.87,;.05,-2.39,;.05,-.85,;-.19,.67,;-1.71,.43,;-1.47,-1.1,;-2.96,1.33,;-2.96,2.87,;-4.36,.7,;-4.76,-.78,;-6.25,-.38,;-5.85,1.1,;-6.17,-1.92,;-7.61,-2.47,;-8.57,-1.28,;-10.06,-1.08,;-7.74,.01,;1.52,-.38,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581642 ((rac)-(2s,4s)-2-(2-(3-(tert-Butyl)phenyl)-8-azaspi...) Show SMILES CC(C)(C)c1cccc(c1)C1CCC2(C1)CCN(CC2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2 |r,wU:22.24,wD:24.27,(7.66,-4.22,;8.36,-2.84,;9.9,-2.76,;9.2,-4.13,;7.52,-1.55,;8.1,-.13,;7.16,1.09,;5.63,.88,;5.05,-.54,;5.99,-1.76,;3.51,-.54,;2.6,-1.79,;1.14,-1.31,;1.14,.23,;2.6,.71,;-.19,-.54,;-1.53,.23,;-1.54,1.77,;-.19,2.54,;1.14,1.77,;-2.79,2.68,;-2.79,4.22,;-4.2,2.05,;-4.6,.56,;-6.08,.96,;-5.68,2.45,;-6,-.58,;-7.44,-1.13,;-8.41,.07,;-9.9,.21,;-7.57,1.36,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581648 ((rac)-(2s,4s)-2-(6-(4-Isopropylphenyl)-2-azaspiro[...) Show SMILES CC(C)c1ccc(cc1)C1CCC2(CN(C2)C(=O)[C@H]2C[C@@]3(C2)COC(=O)N3)C1 |r,wU:18.19,wD:20.22,(9.62,.42,;8.95,-.97,;9.82,-2.24,;7.41,-1.08,;6.74,-2.47,;5.21,-2.58,;4.34,-1.31,;5.01,.08,;6.55,.19,;2.81,-1.42,;1.9,-2.67,;.44,-2.19,;.44,-.65,;-1.05,-1.05,;-1.45,.43,;.04,.83,;-2.78,1.2,;-2.78,2.74,;-4.12,.43,;-4.52,-1.05,;-6,-.65,;-5.6,.83,;-5.92,-2.19,;-7.36,-2.74,;-8.33,-1.55,;-9.82,-1.41,;-7.49,-.26,;1.9,-.18,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581643 ((rac)-(2s,4s)-2-(2-(4-(tert-Butyl)phenyl)-8-azaspi...) Show SMILES CC(C)(C)c1ccc(cc1)C1CCC2(C1)CCN(CC2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2 |r,wU:22.24,wD:24.27,(9.63,-2.96,;8.76,-1.69,;9.41,-.3,;10.29,-1.57,;7.22,-1.81,;6.56,-3.21,;5.03,-3.33,;4.15,-2.06,;4.81,-.67,;6.34,-.55,;2.61,-2.06,;1.71,-3.31,;.24,-2.83,;.24,-1.29,;1.71,-.82,;-1.25,-1.69,;-2.34,-.6,;-1.94,.88,;-.45,1.28,;.64,.19,;-3.18,1.79,;-3.18,3.33,;-4.59,1.16,;-4.99,-.32,;-6.48,.07,;-6.08,1.56,;-6.4,-1.46,;-7.83,-2.01,;-8.8,-.82,;-10.29,-.69,;-7.96,.47,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581634 ((rac)-(2s,4s)-2-(6-(4-(tert-Butyl)phenyl)-2-azaspi...) Show SMILES CC(C)(C)c1ccc(cc1)C1CCC2(CN(C2)C(=O)[C@H]2C[C@@]3(C2)COC(=O)N3)C1 |r,wU:19.20,wD:21.23,(9.17,.26,;8.54,-1.14,;9.45,-2.39,;10.08,-.98,;7.01,-1.3,;6.39,-2.71,;4.85,-2.87,;3.95,-1.62,;4.58,-.22,;6.11,-.06,;2.41,-1.62,;1.5,-2.87,;.04,-2.39,;.04,-.85,;-.2,.67,;-1.72,.43,;-1.48,-1.1,;-2.97,1.33,;-2.97,2.87,;-4.38,.7,;-4.77,-.78,;-6.26,-.38,;-5.86,1.1,;-6.18,-1.92,;-7.62,-2.47,;-8.59,-1.28,;-10.08,-1.15,;-7.75,.01,;1.5,-.38,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581595 ((2s,4s)-2-[2-(2,3-Dimethylphenyl)-7-azaspiro[3.5]n...) Show SMILES Cc1cccc(C2CC3(C2)CCN(CC3)C(=O)[C@H]2C[C@@]3(C2)COC(=O)N3)c1C |r,wU:17.18,wD:19.21,(9.15,-.93,;7.82,-1.7,;7.82,-3.24,;6.48,-4.01,;5.15,-3.24,;5.15,-1.7,;3.81,-.93,;2.33,-1.33,;1.93,.16,;3.42,.56,;.59,-.61,;-.74,.16,;-.74,1.7,;.59,2.47,;1.93,1.7,;-2.07,2.47,;-2.07,4.01,;-3.41,1.7,;-3.8,.21,;-5.29,.61,;-4.89,2.1,;-5.29,-.93,;-6.76,-1.41,;-7.66,-.16,;-9.15,.24,;-6.76,1.09,;6.48,-.93,;6.48,.61,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581646 ((rac)-(2s,4s)-2-(6-(3-Isopropylphenyl)-2-azaspiro[...) Show SMILES CC(C)c1cccc(c1)C1CCC2(CN(C2)C(=O)[C@H]2C[C@@]3(C2)COC(=O)N3)C1 |r,wU:18.19,wD:20.22,(9.48,-2.44,;7.95,-2.55,;7.28,-3.94,;7.08,-1.28,;7.75,.11,;6.88,1.38,;5.35,1.27,;4.68,-.12,;5.54,-1.39,;3.14,-.23,;2.24,-1.48,;.77,-1,;.77,.54,;-.72,.14,;-1.11,1.63,;.37,2.03,;-2.45,2.4,;-2.45,3.94,;-3.78,1.63,;-4.18,.14,;-5.67,.54,;-5.27,2.03,;-5.59,-1,;-7.03,-1.55,;-7.99,-.35,;-9.48,-.22,;-7.16,.94,;2.24,1.01,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581658 ((2s,4s)-2-(6-(3-Cyclobutylphenyl)-2-azaspiro[3.3]h...) Show SMILES O=C([C@H]1C[C@@]2(C1)COC(=O)N2)N1CC2(CC(C2)c2cccc(c2)C2CCC2)C1 |r,wU:2.1,wD:4.4,(-2.62,3.78,;-2.62,2.24,;-3.95,1.47,;-4.35,-.01,;-5.84,.39,;-5.44,1.87,;-5.76,-1.15,;-7.2,-1.7,;-8.17,-.51,;-9.71,-.51,;-7.33,.78,;-1.29,1.47,;-.89,-.01,;.6,.38,;1,-1.1,;2.49,-.7,;2.09,.78,;3.82,-1.47,;3.82,-3.01,;5.15,-3.78,;6.49,-3.01,;6.49,-1.47,;5.15,-.7,;7.82,-.7,;9.31,-1.1,;9.71,.38,;8.22,.78,;.2,1.87,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581625 ((rac)-(2s,4s)-8-Methyl-2-(2-(4-(trifluoromethyl)ph...) Show SMILES CC1OC(=O)N[C@@]11C[C@@H](C1)C(=O)N1CCC2(CCC(C2)c2ccc(cc2)C(F)(F)F)CC1 |r,wU:8.11,wD:6.10,(-5.45,-3.04,;-6.61,-1.89,;-8.12,-2.21,;-8.89,-.87,;-10.43,-.87,;-7.86,.27,;-6.45,-.35,;-4.96,-.75,;-4.56,.73,;-6.05,1.13,;-3.23,1.5,;-3.23,3.04,;-1.9,.73,;-1.9,-.81,;-.56,-1.58,;.77,-.81,;.77,-2.35,;2.24,-2.82,;3.14,-1.58,;2.24,-.33,;4.63,-1.18,;5.72,-2.27,;7.21,-1.87,;7.6,-.38,;6.52,.71,;5.03,.31,;9.09,.02,;10.43,.79,;9.49,1.51,;10.43,-.75,;.77,.73,;-.56,1.5,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581630 ((2s,4s)-2-((R*)-6-(4-(Trifluoromethyl)phenyl)-2-az...) Show SMILES FC(F)(F)c1ccc(cc1)[C@@H]1CCC2(CN(C2)C(=O)[C@H]2C[C@@]3(C2)COC(=O)N3)C1 |r,wU:19.20,wD:10.10,21.23,(9.22,.19,;8.57,-1.21,;9.46,-2.47,;10.11,-1.08,;7.04,-1.35,;6.39,-2.74,;4.85,-2.88,;3.97,-1.62,;4.62,-.22,;6.15,-.09,;2.43,-1.62,;1.52,-2.86,;.06,-2.39,;.06,-.85,;-.18,.67,;-1.7,.43,;-1.46,-1.09,;-2.95,1.34,;-2.95,2.88,;-4.36,.71,;-4.75,-.78,;-6.24,-.38,;-5.84,1.11,;-6.16,-1.92,;-7.6,-2.47,;-8.57,-1.27,;-10.11,-1.15,;-7.73,.02,;1.52,-.37,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581645 ((2s,4s)-2-(2-(3-(tert-Butyl)phenyl)-6-azaspiro[3.4...) Show SMILES CC(C)(C)c1cccc(c1)C1CC2(C1)CCN(C2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2 |r,wU:20.22,wD:22.25,(9.63,-1.89,;8.09,-2.01,;7.42,-3.39,;8.86,-3.34,;7.23,-.73,;7.89,.65,;7.03,1.93,;5.49,1.81,;4.82,.43,;5.69,-.85,;3.29,.31,;2.2,-.78,;1.11,.31,;2.2,1.4,;.2,-.93,;-1.26,-.46,;-1.26,1.08,;.2,1.56,;-2.59,1.85,;-2.59,3.39,;-3.93,1.08,;-4.33,-.4,;-5.81,-.01,;-5.42,1.48,;-5.73,-1.54,;-7.17,-2.1,;-8.14,-.9,;-9.63,-.83,;-7.3,.39,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.280	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581652 ((2s,4s)-2-(6-(3-Isopropylphenyl)-2-azaspiro[3.3]he...) Show SMILES CC(C)c1cccc(c1)C1CC2(C1)CN(C2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2 |r,wU:18.20,wD:20.23,(9.4,-1.47,;8.07,-.7,;8.07,.84,;6.74,-1.47,;6.74,-3.01,;5.4,-3.78,;4.07,-3.01,;4.07,-1.47,;5.4,-.7,;2.74,-.7,;1.25,-1.1,;.85,.38,;2.34,.78,;-.64,-.01,;-1.04,1.47,;.45,1.87,;-2.37,2.24,;-2.37,3.78,;-3.7,1.47,;-4.1,-.01,;-5.59,.39,;-5.19,1.87,;-5.51,-1.15,;-6.95,-1.7,;-7.92,-.51,;-9.4,-.3,;-7.08,.78,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.280	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581657 ((2s,4s)-2-(6-(3-Cyclopropylphenyl)-2-azaspiro[3.3]...) Show SMILES O=C([C@H]1C[C@@]2(C1)COC(=O)N2)N1CC2(CC(C2)c2cccc(c2)C2CC2)C1 |r,wU:2.1,wD:4.4,(-2.45,3.78,;-2.45,2.24,;-3.78,1.47,;-4.18,-.01,;-5.67,.39,;-5.27,1.87,;-5.59,-1.15,;-7.02,-1.7,;-7.99,-.51,;-9.53,-.51,;-7.15,.78,;-1.11,1.47,;-.71,-.01,;.77,.38,;1.17,-1.1,;2.66,-.7,;2.26,.78,;3.99,-1.47,;3.99,-3.01,;5.33,-3.78,;6.66,-3.01,;6.66,-1.47,;5.33,-.7,;7.99,-.7,;9.53,-.7,;8.76,.63,;.37,1.87,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581629 ((rac)-(2s,4s)-2-(6-(4-(Trifluoromethyl)phenyl)-2-a...) Show SMILES FC(F)(F)c1ccc(cc1)C1CCC2(CN(C2)C(=O)[C@H]2C[C@@]3(C2)COC(=O)N3)C1 |r,wU:19.20,wD:21.23,(9.23,.19,;8.55,-1.19,;9.4,-2.47,;10.09,-1.09,;7.01,-1.29,;6.33,-2.67,;4.79,-2.77,;3.94,-1.49,;4.62,-.11,;6.16,-.01,;2.4,-1.62,;1.49,-2.87,;.03,-2.39,;.03,-.85,;-.21,.67,;-1.73,.43,;-1.49,-1.1,;-2.98,1.33,;-2.98,2.87,;-4.39,.7,;-4.78,-.78,;-6.27,-.38,;-5.87,1.1,;-6.19,-1.92,;-7.63,-2.47,;-8.6,-1.28,;-10.09,-.88,;-7.76,.01,;1.49,-.38,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.320	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581620 ((2s,4s)-2-(2-(2-(tert-Butyl)pyrimidin-4-yl)-7-azas...) Show SMILES CC(C)(C)c1nccc(n1)C1CC2(C1)CCN(CC2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2 |r,wU:21.23,wD:23.26,(9.88,-.16,;8.54,-.93,;8.54,.61,;9.88,-1.7,;7.21,-1.7,;7.21,-3.24,;5.88,-4.01,;4.54,-3.24,;4.54,-1.7,;5.88,-.93,;3.21,-.93,;1.72,-1.33,;1.32,.16,;2.81,.56,;-.01,-.61,;-1.35,.16,;-1.35,1.7,;-.01,2.47,;1.32,1.7,;-2.68,2.47,;-2.68,4.01,;-4.01,1.7,;-4.41,.21,;-5.9,.61,;-5.5,2.1,;-6.06,-.92,;-7.57,-1.24,;-8.34,.09,;-9.88,.09,;-7.31,1.24,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.350	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581601 ((2r,4s)-2-(2-(6-(tert-Butyl)pyridin-2-yl)-7-azaspi...) Show SMILES CC(C)(C)c1cccc(n1)C1CC2(C1)CCN(CC2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2 |r,wU:21.23,wD:23.26,(9.88,-.16,;8.54,-.93,;8.54,.61,;9.88,-1.7,;7.21,-1.7,;7.21,-3.24,;5.88,-4.01,;4.54,-3.24,;4.54,-1.7,;5.88,-.93,;3.21,-.93,;1.72,-1.33,;1.32,.16,;2.81,.56,;-.01,-.61,;-1.35,.16,;-1.35,1.7,;-.01,2.47,;1.32,1.7,;-2.68,2.47,;-2.68,4.01,;-4.01,1.7,;-4.41,.21,;-5.9,.61,;-5.5,2.1,;-6.06,-.92,;-7.57,-1.24,;-8.34,.09,;-9.88,.09,;-7.31,1.24,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.360	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581612 ((2r,4s)-2-(2-(5-(tert-Butyl)-2-methoxyphenyl)-7-az...) Show SMILES COc1ccc(cc1C1CC2(C1)CCN(CC2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2)C(C)(C)C |r,wU:19.21,wD:21.24,(1.87,-3.24,;3.21,-4.01,;4.54,-3.24,;5.88,-4.01,;7.21,-3.24,;7.21,-1.7,;5.88,-.93,;4.54,-1.7,;3.21,-.93,;1.72,-1.33,;1.32,.16,;2.81,.56,;-.01,-.61,;-1.35,.16,;-1.35,1.7,;-.01,2.47,;1.32,1.7,;-2.68,2.47,;-2.68,4.01,;-4.01,1.7,;-4.41,.21,;-5.9,.61,;-5.5,2.1,;-6.06,-.92,;-7.57,-1.24,;-8.34,.09,;-9.88,.09,;-7.31,1.24,;8.54,-.93,;9.88,-.16,;8.54,.61,;9.88,-1.7,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581608 ((2r,4s)-2-(2-(5-(tert-Butyl)-2-ethoxyphenyl)-7-aza...) Show SMILES CCOc1ccc(cc1C1CC2(C1)CCN(CC2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2)C(C)(C)C |r,wU:20.22,wD:22.25,$;;;;;;;;;;;;;;;;;;;;;;;;;;;;N;;;;$,(.54,-4.01,;1.87,-3.24,;3.21,-4.01,;4.54,-3.24,;5.88,-4.01,;7.21,-3.24,;7.21,-1.7,;5.88,-.93,;4.54,-1.7,;3.21,-.93,;1.72,-1.33,;1.32,.16,;2.81,.56,;-.01,-.61,;-1.35,.16,;-1.35,1.7,;-.01,2.47,;1.32,1.7,;-2.68,2.47,;-2.68,4.01,;-4.01,1.7,;-4.41,.21,;-5.9,.61,;-5.5,2.1,;-6.06,-.92,;-7.57,-1.24,;-8.34,.09,;-9.88,.09,;-7.31,1.24,;8.54,-.93,;9.88,-.16,;8.54,.61,;9.88,-1.7,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.490	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581598 ((2s,4s)-2-[2-(2-(Tert-butyl)pyridin-4-yl)-7-azaspi...) Show SMILES CC(C)(C)c1cc(ccn1)C1CC2(C1)CCN(CC2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2 |r,wU:21.23,wD:23.26,(9.82,-.16,;8.48,-.93,;8.48,.61,;9.82,-1.7,;7.15,-1.7,;5.82,-.93,;4.48,-1.7,;4.48,-3.24,;5.82,-4.01,;7.15,-3.24,;3.15,-.93,;1.66,-1.33,;1.26,.16,;2.75,.56,;-.07,-.61,;-1.41,.16,;-1.41,1.7,;-.07,2.47,;1.26,1.7,;-2.74,2.47,;-2.74,4.01,;-4.07,1.7,;-4.47,.21,;-5.96,.61,;-5.56,2.1,;-5.96,-.93,;-7.42,-1.41,;-8.33,-.16,;-9.82,.24,;-7.42,1.09,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.540	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581659 ((2s,4s)-2-(6-(2,3-Dihydro-1H-inden-5-yl)-2-azaspir...) Show SMILES O=C([C@H]1C[C@@]2(C1)COC(=O)N2)N1CC2(CC(C2)c2ccc3CCCc3c2)C1 |r,wU:2.1,wD:4.4,(-2.14,3.78,;-2.14,2.24,;-3.48,1.47,;-3.88,-.01,;-5.36,.39,;-4.97,1.87,;-5.52,-1.15,;-7.03,-1.47,;-7.8,-.13,;-9.33,.03,;-6.77,1.01,;-.81,1.47,;.68,1.87,;1.08,.39,;2.56,.78,;2.96,-.7,;1.47,-1.1,;4.3,-1.47,;4.3,-3.01,;5.63,-3.78,;6.96,-3.01,;8.43,-3.49,;9.33,-2.24,;8.43,-1,;6.96,-1.47,;5.63,-.7,;-.41,-.01,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.620	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581638 ((rac)-(2s,4s)-2-(6-Cyclohexyl-2-azaspiro[3.4]octan...) Show SMILES O=C([C@H]1C[C@@]2(C1)COC(=O)N2)N1CC2(C1)CCC(C2)C1CCCCC1 |r,wU:2.1,wD:4.4,(-1.44,2.88,;-1.44,1.34,;-2.85,.71,;-3.25,-.77,;-4.73,-.37,;-4.33,1.11,;-4.65,-1.91,;-6.09,-2.46,;-7.06,-1.27,;-8.55,-1.06,;-6.22,.02,;-.19,.44,;1.33,.68,;1.57,-.84,;.05,-1.09,;1.57,-2.38,;3.03,-2.86,;3.94,-1.61,;3.03,-.37,;5.48,-1.61,;6.35,-2.88,;7.89,-2.76,;8.55,-1.37,;7.67,-.1,;6.14,-.22,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.710	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581661 ((2s,4s)-2-(7-Phenyl-2-azaspiro[3.5]nonane-2-carbon...) Show SMILES O=C([C@H]1C[C@@]2(C1)COC(=O)N2)N1CC2(C1)CCC(CC2)c1ccccc1 |r,wU:2.1,wD:4.4,(-1.35,4.01,;-1.35,2.47,;-2.68,1.7,;-3.08,.21,;-4.57,.61,;-4.17,2.1,;-4.73,-.92,;-6.24,-1.24,;-7.01,.09,;-8.54,.25,;-5.98,1.24,;-.02,1.7,;1.47,2.1,;1.87,.61,;.38,.21,;1.87,-.93,;3.2,-1.7,;4.54,-.93,;4.54,.61,;3.2,1.38,;5.87,-1.7,;5.87,-3.24,;7.2,-4.01,;8.54,-3.24,;8.54,-1.7,;7.2,-.93,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.730	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581607 ((2r,4s)-2-(2-(5-(tert-Butyl)-2-fluorophenyl)-7-aza...) Show SMILES CC(C)(C)c1ccc(F)c(c1)C1CC2(C1)CCN(CC2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2 |r,wU:22.24,wD:24.27,(9.88,-.16,;8.54,-.93,;8.54,.61,;9.88,-1.7,;7.21,-1.7,;7.21,-3.24,;5.88,-4.01,;4.54,-3.24,;3.21,-4.01,;4.54,-1.7,;5.88,-.93,;3.21,-.93,;1.72,-1.33,;1.32,.16,;2.81,.56,;-.01,-.61,;-1.35,.16,;-1.35,1.7,;-.01,2.47,;1.32,1.7,;-2.68,2.47,;-2.68,4.01,;-4.01,1.7,;-4.41,.21,;-5.9,.61,;-5.5,2.1,;-6.06,-.92,;-7.57,-1.24,;-8.34,.09,;-9.88,.09,;-7.31,1.24,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.820	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581617 ((2s,4s)-2-(2-(3-Fluoro-6-(trifluoromethyl)pyridin-...) Show SMILES Fc1ccc(nc1C1CC2(C1)CCN(CC2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2)C(F)(F)F |r,wU:18.20,wD:20.23,(3.21,-4.01,;4.54,-3.24,;5.88,-4.01,;7.21,-3.24,;7.26,-1.67,;5.88,-.93,;4.54,-1.7,;3.21,-.93,;1.72,-1.33,;1.32,.16,;2.81,.56,;-.01,-.61,;-1.35,.16,;-1.35,1.7,;-.01,2.47,;1.32,1.7,;-2.68,2.47,;-2.68,4.01,;-4.01,1.7,;-4.41,.21,;-5.9,.61,;-5.5,2.1,;-6.06,-.92,;-7.57,-1.24,;-8.34,.09,;-9.88,.09,;-7.31,1.24,;8.59,-.9,;9.92,-.13,;9.36,-2.24,;7.82,.43,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.860	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581633 ((2r,4R*)-2-((S*)-6-(4-(Trifluoromethyl)phenyl)-2-a...) Show SMILES FC(F)(F)c1ccc(cc1)[C@H]1CCC2(CN(C2)C(=O)[C@H]2C[C@@]3(C2)COC(=O)N3)C1 |r,wU:10.10,19.20,wD:21.23,(9.18,.23,;8.54,-1.17,;9.44,-2.42,;10.08,-1.02,;7.01,-1.32,;6.38,-2.72,;4.84,-2.87,;3.95,-1.62,;4.58,-.22,;6.12,-.07,;2.41,-1.62,;1.5,-2.87,;.04,-2.39,;.04,-.85,;-.2,.67,;-1.72,.43,;-1.48,-1.09,;-2.97,1.33,;-2.97,2.87,;-4.38,.71,;-4.78,-.78,;-6.26,-.38,;-5.87,1.11,;-6.18,-1.92,;-7.62,-2.47,;-8.59,-1.27,;-10.08,-1.08,;-7.75,.02,;1.5,-.38,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.870	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581644 ((2s,4s)-2-(2-(3-Isopropylphenyl)-6-azaspiro[3.4]oc...) Show SMILES CC(C)c1cccc(c1)C1CC2(C1)CCN(C2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2 |r,wU:19.21,wD:21.24,(7.56,-3.25,;8.17,-1.84,;9.7,-1.66,;7.25,-.6,;7.86,.81,;6.94,2.05,;5.41,1.87,;4.8,.45,;5.72,-.78,;3.26,.38,;2.23,-.76,;1.09,.28,;2.12,1.42,;.24,-1.01,;-1.24,-.6,;-1.33,.94,;.12,1.48,;-2.67,1.71,;-2.67,3.25,;-4,.94,;-4.4,-.55,;-5.89,-.15,;-5.49,1.34,;-5.81,-1.69,;-7.24,-2.24,;-8.21,-1.04,;-9.7,-.99,;-7.37,.25,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.870	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581606 ((2s,4s)-2-(2-(4-(tert-Butyl)pyridin-2-yl)-7-azaspi...) Show SMILES CC(C)(C)c1ccnc(c1)C1CC2(C1)CCN(CC2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2 |r,wU:21.23,wD:23.26,(9.88,-.16,;8.54,-.93,;8.54,.61,;9.88,-1.7,;7.21,-1.7,;7.21,-3.24,;5.88,-4.01,;4.54,-3.24,;4.54,-1.7,;5.88,-.93,;3.21,-.93,;1.72,-1.33,;1.32,.16,;2.81,.56,;-.01,-.61,;-1.35,.16,;-1.35,1.7,;-.01,2.47,;1.32,1.7,;-2.68,2.47,;-2.68,4.01,;-4.01,1.7,;-4.41,.21,;-5.9,.61,;-5.5,2.1,;-6.06,-.92,;-7.57,-1.24,;-8.34,.09,;-9.88,.09,;-7.31,1.24,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581654 ((2s,4s)-2-(6-Cyclohexyl-2-azaspiro[3.3]heptane-2-c...) Show SMILES O=C([C@H]1C[C@@]2(C1)COC(=O)N2)N1CC2(CC(C2)C2CCCCC2)C1 |r,wU:2.1,wD:4.4,(-1.04,3.78,;-1.04,2.24,;-2.37,1.47,;-2.77,-.01,;-4.26,.39,;-3.86,1.87,;-4.18,-1.15,;-5.61,-1.7,;-6.58,-.51,;-8.07,-.3,;-5.74,.78,;.3,1.47,;.7,-.01,;2.18,.38,;2.58,-1.1,;4.07,-.7,;3.67,.78,;5.4,-1.47,;5.4,-3.01,;6.74,-3.78,;8.07,-3.01,;8.07,-1.47,;6.74,-.7,;1.78,1.87,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581636 ((rac)-(2s,4s)-2-(6-(3-(tert-Butyl)phenyl)-2-azaspi...) Show SMILES CC1OC(=O)N[C@@]11C[C@@H](C1)C(=O)N1CC2(C1)CCC(C2)c1cccc(c1)C(C)(C)C |r,wU:8.11,wD:6.10,(-4.3,-1.56,;-5.59,-.72,;-7.03,-1.27,;-8,-.08,;-9.48,.13,;-7.16,1.22,;-5.67,.82,;-4.18,.42,;-3.78,1.91,;-5.27,2.3,;-2.38,2.53,;-2.38,4.07,;-1.13,1.63,;.39,1.87,;.63,.35,;-.89,.11,;.63,-1.19,;2.1,-1.67,;3,-.42,;2.1,.82,;4.54,-.42,;5.12,1,;6.65,1.21,;7.59,-0,;7.01,-1.43,;5.49,-1.64,;7.96,-2.65,;9.48,-2.44,;7.38,-4.07,;8.9,-3.86,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581653 ((2s,4s)-2-(6-(3,4-Dimethylphenyl)-2-azaspiro[3.3]h...) Show SMILES Cc1ccc(cc1C)C1CC2(C1)CN(C2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2 |r,wU:17.19,wD:19.22,(8.74,-3.78,;7.4,-3.01,;6.07,-3.78,;4.74,-3.01,;4.74,-1.47,;6.07,-.7,;7.4,-1.47,;8.74,-.7,;3.4,-.7,;1.91,-1.1,;1.52,.38,;3,.78,;.03,-.01,;-.37,1.47,;1.12,1.87,;-1.7,2.24,;-1.7,3.78,;-3.04,1.47,;-3.44,-.01,;-4.92,.39,;-4.52,1.87,;-4.84,-1.15,;-6.28,-1.7,;-7.25,-.51,;-8.74,-.37,;-6.41,.78,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581613 ((2s,4s)-2-(2-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl...) Show SMILES FC1(F)Oc2ccc(cc2O1)C1CC2(C1)CCN(CC2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2 |r,wU:22.25,wD:24.28,(10.39,-1.7,;9.06,-2.47,;10.39,-3.24,;8.16,-3.72,;6.69,-3.24,;5.36,-4.01,;4.02,-3.24,;4.02,-1.7,;5.36,-.93,;6.69,-1.7,;8.16,-1.22,;2.69,-.93,;1.2,-1.33,;.8,.16,;2.29,.56,;-.53,-.61,;-1.86,.16,;-1.86,1.7,;-.53,2.47,;.8,1.7,;-3.2,2.47,;-3.2,4.01,;-4.53,1.7,;-4.93,.21,;-6.42,.61,;-6.02,2.1,;-6.58,-.92,;-8.08,-1.24,;-8.85,.09,;-10.39,.09,;-7.82,1.24,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581640 ((rac)-(2s,4s)-2-(6-Cyclopentyl-2-azaspiro[3.4]octa...) Show SMILES O=C([C@H]1C[C@@]2(C1)COC(=O)N2)N1CC2(C1)CCC(C2)C1CCCC1 |r,wU:2.1,wD:4.4,(-1.14,2.87,;-1.14,1.33,;-2.54,.7,;-2.94,-.78,;-4.43,-.38,;-4.03,1.1,;-4.35,-1.92,;-5.79,-2.47,;-6.76,-1.28,;-8.24,-1.07,;-5.92,.01,;.11,.43,;1.63,.67,;1.87,-.85,;.35,-1.1,;1.87,-2.39,;3.34,-2.87,;4.24,-1.62,;3.34,-.38,;5.78,-1.62,;6.87,-2.71,;8.24,-2.01,;8,-.49,;6.48,-.25,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581545 ((2s,4s)-2-[2-(m-Tolyl)-7-azaspiro[3.5]nonane-7-car...) Show SMILES Cc1cccc(c1)C1CC2(C1)CCN(CC2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2 |r,wU:18.20,wD:20.23,(9.15,-.93,;7.82,-1.7,;7.82,-3.24,;6.48,-4.01,;5.15,-3.24,;5.15,-1.7,;6.48,-.93,;3.81,-.93,;2.33,-1.33,;1.93,.16,;3.42,.56,;.59,-.61,;-.74,.16,;-.74,1.7,;.59,2.47,;1.93,1.7,;-2.07,2.47,;-2.07,4.01,;-3.41,1.7,;-3.8,.21,;-5.29,.61,;-4.89,2.1,;-5.29,-.93,;-6.76,-1.41,;-7.66,-.16,;-9.15,.24,;-6.76,1.09,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581655 ((2s,4s)-2-(6-(3,5-Dimethylphenyl)-2-azaspiro[3.3]h...) Show SMILES Cc1cc(C)cc(c1)C1CC2(C1)CN(C2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2 |r,wU:17.19,wD:19.22,(8.74,.07,;7.4,-.7,;7.4,-2.24,;6.07,-3.01,;6.07,-4.55,;4.74,-2.24,;4.74,-.7,;6.07,.07,;3.4,.07,;1.91,-.33,;1.52,1.15,;3,1.55,;.03,.76,;-.37,2.24,;1.12,2.64,;-1.7,3.01,;-1.7,4.55,;-3.04,2.24,;-3.44,.76,;-4.92,1.16,;-4.52,2.64,;-4.84,-.38,;-6.28,-.93,;-7.25,.26,;-8.74,.47,;-6.41,1.55,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581610 ((2r,4s)-2-[2-(3-Isopropylphenyl)-7-azaspiro[3.5]no...) Show SMILES CC(C)c1cccc(c1)C1CC2(C1)CCN(CC2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2 |r,wU:20.22,wD:22.25,(8.54,.61,;8.54,-.93,;9.88,-1.7,;7.21,-1.7,;7.21,-3.24,;5.88,-4.01,;4.54,-3.24,;4.54,-1.7,;5.88,-.93,;3.21,-.93,;1.72,-1.33,;1.32,.16,;2.81,.56,;-.01,-.61,;-1.35,.16,;-1.35,1.7,;-.01,2.47,;1.32,1.7,;-2.68,2.47,;-2.68,4.01,;-4.01,1.7,;-4.41,.21,;-5.9,.61,;-5.5,2.1,;-6.06,-.92,;-7.57,-1.24,;-8.34,.09,;-9.88,.09,;-7.31,1.24,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581622 ((2s,4s)-2-[2-(2-(tert-Butyl)oxazol-5-yl)-7-azaspir...) Show SMILES CC(C)(C)c1ncc(o1)C1CC2(C1)CCN(CC2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2 |r,wU:20.22,wD:22.25,(9.92,-1.65,;8.43,-2.05,;8.83,-.56,;9.52,-3.14,;6.94,-2.45,;6.17,-3.78,;4.66,-3.46,;4.5,-1.93,;5.91,-1.3,;3.17,-1.16,;1.68,-1.56,;1.28,-.07,;2.77,.33,;-.05,-.84,;-1.38,-.07,;-1.38,1.47,;-.05,2.24,;1.28,1.47,;-2.72,2.24,;-2.72,3.78,;-4.05,1.47,;-4.45,-.02,;-5.94,.38,;-5.54,1.87,;-6.1,-1.15,;-7.61,-1.47,;-8.38,-.14,;-9.92,-.14,;-7.34,1.01,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581632 ((2r,4S*)-2-((R*)-6-(4-(Trifluoromethyl)phenyl)-2-a...) Show SMILES FC(F)(F)c1ccc(cc1)[C@@H]1CCC2(CN(C2)C(=O)[C@H]2C[C@@]3(C2)COC(=O)N3)C1 |r,wU:19.20,wD:10.10,21.23,(9.2,.19,;8.55,-1.21,;9.43,-2.47,;10.08,-1.07,;7.01,-1.35,;6.36,-2.74,;4.83,-2.88,;3.94,-1.62,;4.59,-.22,;6.13,-.09,;2.4,-1.62,;1.5,-2.86,;.03,-2.39,;.03,-.85,;-.21,.67,;-1.73,.43,;-1.49,-1.09,;-2.97,1.34,;-2.97,2.88,;-4.38,.71,;-4.78,-.78,;-6.27,-.38,;-5.87,1.11,;-6.19,-1.92,;-7.62,-2.47,;-8.59,-1.27,;-10.08,-1.07,;-7.75,.02,;1.5,-.37,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581504 ((2s,4s)-2-(2-(o-Tolyl)-7-azaspiro[3.5]nonane-7-car...) Show SMILES Cc1ccccc1C1CC2(C1)CCN(CC2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2 |r,wU:18.20,wD:20.23,(7.15,.61,;7.15,-.93,;8.48,-1.7,;8.48,-3.24,;7.15,-4.01,;5.82,-3.24,;5.82,-1.7,;4.48,-.93,;2.99,-1.33,;2.6,.16,;4.08,.56,;1.26,-.61,;-.07,.16,;-.07,1.7,;1.26,2.47,;2.6,1.7,;-1.41,2.47,;-1.41,4.01,;-2.74,1.7,;-3.14,.21,;-4.63,.61,;-4.23,2.1,;-4.63,-.93,;-6.09,-1.41,;-7,-.16,;-8.48,.24,;-6.09,1.09,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM581603 ((2r,4s)-2-[2-[3-Chloro-4-(trifluoromethyl)phenyl]-...) Show SMILES FC(F)(F)c1ccc(cc1Cl)C1CC2(C1)CCN(CC2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2 |r,wU:22.24,wD:24.27,(9.92,-4.14,;8.59,-3.37,;7.82,-4.7,;9.36,-2.04,;7.26,-2.6,;5.88,-3.34,;4.54,-2.57,;4.54,-1.03,;5.88,-.26,;7.21,-1.03,;8.54,-.26,;3.21,-.26,;1.72,-.66,;1.32,.83,;2.81,1.22,;-.01,.06,;-1.35,.83,;-1.35,2.37,;-.01,3.14,;1.32,2.37,;-2.68,3.14,;-2.68,4.68,;-4.01,2.37,;-4.41,.88,;-5.9,1.28,;-5.5,2.76,;-6.06,-.25,;-7.57,-.57,;-8.34,.76,;-9.88,.76,;-7.31,1.9,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S186B3
					More data for this Ligand-Target Pair

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