Found 422 hits Enz. Inhib. hit(s) with all data for entry = 11742 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643616
(US20240002391, Compound 776)Show SMILES COc1nc(N[C@H]2CCN(C[C@H]2F)C(=O)C2(CC2)C#N)nn2ccc(-c3ccc(N=N)c(NCC(F)F)c3)c12 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643617
(US20240002391, Compound 777)Show SMILES COc1nc(N[C@@H]2CCN(C)CC2(F)F)nn2ccc(-c3ccc(N=N)c(NCC(F)F)c3)c12 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643618
(US20240002391, Compound 780)Show SMILES CCN1CC[C@@H](Nc2nc(OC)c3c(ccn3n2)-c2ccc3nnn(CC(F)F)c3c2)C(F)(F)C1 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643619
(US20240002391, Compound 785)Show SMILES COc1nc(N[C@@H]2CCN(CC2(F)F)C2COC2)nn2ccc(-c3ccc4nnn(CC(F)F)c4c3)c12 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643620
(US20240002391, Compound 788)Show SMILES COc1nc(N[C@@H]2CCN(CC2(F)F)C(C)=O)nn2ccc(-c3ccc4nnn(CC(F)F)c4c3)c12 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643621
(US20240002391, Compound 791)Show SMILES COc1nc(N[C@@H]2CCN(CC2(F)F)C(=O)C2(CC2)C#N)nn2ccc(-c3ccc4nnn(CC(F)F)c4c3)c12 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643622
(US20240002391, Compound 793)Show SMILES COc1nc(NC2CCC(=O)N(C)C2)nn2ccc(-c3ccc4nnn(CC(F)F)c4c3)c12 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643623
(US20240002391, Compound 798)Show SMILES COc1nc(NC23CCC(O)(CC2)C3)nn2ccc(-c3ccc4nnn(CC(F)F)c4c3)c12 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643624
(US20240002391, Compound 799)Show SMILES COc1nc(NC2CCC3(CN(C3)C(C)=O)CC2)nn2ccc(-c3ccc4nnn(CC(F)F)c4c3)c12 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643625
(US20240002391, Compound 801)Show SMILES COc1nc(NC2CCC3(COC3)CC2)nn2ccc(-c3ccc4nnn(CC(F)F)c4c3)c12 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643626
(US20240002391, Compound 805)Show SMILES COc1nc(N[C@H]2C[C@](C)(C2)NC(C)=O)nn2ccc(-c3cc(F)c4nnn(CC(F)F)c4c3)c12 |r,wU:8.8,wD:6.5,8.11,(-2.9,-.11,;-1.56,-.88,;-1.56,-2.42,;-.23,-3.19,;-.23,-4.73,;1.1,-5.5,;2.44,-4.73,;3.93,-5.13,;4.32,-3.64,;4.32,-2.1,;2.84,-3.25,;5.66,-2.87,;6.99,-3.64,;8.33,-2.87,;6.99,-5.18,;-1.56,-5.5,;-2.9,-4.73,;-4.36,-5.21,;-5.27,-3.96,;-4.36,-2.72,;-4.84,-1.25,;-6.34,-.93,;-6.82,.53,;-8.33,.85,;-5.79,1.68,;-5.95,3.21,;-4.54,3.83,;-3.51,2.69,;-1.98,2.85,;-1.35,4.26,;-2.26,5.5,;.18,4.42,;-4.28,1.36,;-3.81,-.11,;-2.9,-3.19,)| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643627
(US20240002391, Compound 806)Show SMILES COc1nc(N[C@H]2C[C@@](C)(C2)NC(C)=O)nn2ccc(-c3cc(F)c4nnn(CC(F)F)c4c3)c12 |r,wU:8.11,wD:6.5,8.8,(-2.9,-.11,;-1.56,-.88,;-1.56,-2.42,;-.23,-3.19,;-.23,-4.73,;1.1,-5.5,;2.44,-4.73,;3.93,-5.13,;4.32,-3.64,;4.32,-2.1,;2.84,-3.25,;5.66,-2.87,;6.99,-3.64,;8.33,-2.87,;6.99,-5.18,;-1.56,-5.5,;-2.9,-4.73,;-4.36,-5.21,;-5.27,-3.96,;-4.36,-2.72,;-4.84,-1.25,;-6.34,-.93,;-6.82,.53,;-8.33,.85,;-5.79,1.68,;-5.95,3.21,;-4.54,3.83,;-3.51,2.69,;-1.98,2.85,;-1.35,4.26,;-2.26,5.5,;.18,4.42,;-4.28,1.36,;-3.81,-.11,;-2.9,-3.19,)| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643628
(US20240002391, Compound 810)Show SMILES COc1nc(N[C@H]2CC[C@@](C)(O)CC2)nn2ccc(-c3cc(F)c4nnn(CC(F)F)c4c3)c12 |r,wU:9.9,wD:6.5,9.10,(-1.95,-.11,;-.62,-.88,;-.62,-2.42,;.71,-3.19,;.71,-4.73,;2.05,-5.5,;3.38,-4.73,;4.72,-5.5,;6.05,-4.73,;6.05,-3.19,;6.05,-1.65,;7.38,-2.42,;4.72,-2.42,;3.38,-3.19,;-.62,-5.5,;-1.95,-4.73,;-3.42,-5.21,;-4.32,-3.96,;-3.42,-2.72,;-3.89,-1.25,;-5.4,-.93,;-5.88,.53,;-7.38,.85,;-4.85,1.68,;-5.01,3.21,;-3.6,3.83,;-2.57,2.69,;-1.04,2.85,;-.41,4.26,;-1.32,5.5,;1.12,4.42,;-3.34,1.36,;-2.86,-.11,;-1.95,-3.19,)| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 10.9 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643629
(US20240002391, Compound 811)Show SMILES COc1nc(N[C@H]2CC[C@](C)(O)CC2)nn2ccc(-c3cc(F)c4nnn(CC(F)F)c4c3)c12 |r,wU:9.10,wD:6.5,9.9,(-1.95,-.11,;-.62,-.88,;-.62,-2.42,;.71,-3.19,;.71,-4.73,;2.05,-5.5,;3.38,-4.73,;4.72,-5.5,;6.05,-4.73,;6.05,-3.19,;6.05,-1.65,;7.38,-2.42,;4.72,-2.42,;3.38,-3.19,;-.62,-5.5,;-1.95,-4.73,;-3.42,-5.21,;-4.32,-3.96,;-3.42,-2.72,;-3.89,-1.25,;-5.4,-.93,;-5.88,.53,;-7.38,.85,;-4.85,1.68,;-5.01,3.21,;-3.6,3.83,;-2.57,2.69,;-1.04,2.85,;-.41,4.26,;-1.32,5.5,;1.12,4.42,;-3.34,1.36,;-2.86,-.11,;-1.95,-3.19,)| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643630
(US20240002391, Compound 812)Show SMILES COc1nc(N[C@@H]2CC(C[C@@H]2F)C(C)=O)nn2ccc(-c3cc(F)c4nnn(CC(F)F)c4c3)c12 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643631
(US20240002391, Compound 816)Show SMILES COc1nc(N[C@H]2CCN(C[C@H]2F)C(C)=O)nn2ccc(-c3cc(F)c4nnn(CC(F)F)c4c3)c12 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643632
(US20240002391, Compound 818)Show SMILES COc1nc(N[C@H]2CCN(C[C@H]2F)C2COC2)nn2ccc(-c3cc(F)c4nnn(CC(F)F)c4c3)c12 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643633
(US20240002391, Compound 821)Show SMILES COc1nc(N[C@@H]2CCN(CC2(F)F)C(C)=O)nn2ccc(-c3cc(F)c4nnn(CC(F)F)c4c3)c12 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643634
(US20240002391, Compound 822)Show SMILES COc1nc(N[C@@H]2CCN(CC2(F)F)C2COC2)nn2ccc(-c3cc(F)c4nnn(CC(F)F)c4c3)c12 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643635
(US20240002391, Compound 856)Show SMILES COc1nc(N[C@H]2CCN(C[C@H]2F)C(C)=O)nn2cc(F)c(-c3ccc4nnn(CC(F)F)c4c3)c12 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643636
(US20240002391, Compound 904)Show SMILES COc1nc(N[C@H]2C[C@H](C2)OCCO)nn2ccc(-c3ccc4nnn(CC(F)(F)F)c4c3)c12 |r,wD:6.5,8.10,(-4.28,-.19,;-2.95,-.96,;-2.95,-2.5,;-1.62,-3.27,;-1.62,-4.81,;-.28,-5.56,;1.05,-4.78,;2.54,-5.16,;2.92,-3.66,;1.43,-3.28,;4.24,-2.88,;5.59,-3.63,;6.91,-2.84,;8.25,-3.59,;-2.95,-5.58,;-4.28,-4.81,;-5.75,-5.28,;-6.65,-4.04,;-5.75,-2.79,;-6.25,-1.33,;-7.76,-1.03,;-8.25,.42,;-7.24,1.58,;-7.42,3.11,;-6.02,3.76,;-4.98,2.63,;-3.45,2.81,;-2.84,4.23,;-2.24,5.64,;-1.43,3.62,;-4.26,4.83,;-5.73,1.28,;-5.23,-.17,;-4.28,-3.27,)| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643637
(US20240002391, Compound 905)Show SMILES COc1nc(N[C@H]2C[C@](C)(C2)NC(C)=O)nn2ccc(-c3ccc4nnn(CC(F)(F)F)c4c3)c12 |r,wU:8.8,wD:6.5,8.11,(-3.61,-.19,;-2.28,-.96,;-2.28,-2.5,;-.95,-3.27,;-.95,-4.81,;.4,-5.56,;1.72,-4.78,;3.21,-5.16,;3.59,-3.66,;3.59,-2.12,;2.1,-3.28,;4.92,-2.88,;6.26,-3.63,;7.58,-2.84,;6.26,-5.17,;-2.28,-5.58,;-3.61,-4.81,;-5.08,-5.28,;-5.98,-4.04,;-5.08,-2.79,;-5.57,-1.33,;-7.09,-1.03,;-7.58,.42,;-6.57,1.58,;-6.75,3.11,;-5.35,3.76,;-4.31,2.63,;-2.78,2.81,;-2.17,4.23,;-1.56,5.64,;-.76,3.62,;-3.59,4.83,;-5.06,1.28,;-4.56,-.17,;-3.61,-3.27,)| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643638
(US20240002391, Compound 910)Show SMILES COc1nc(N[C@H]2CC[C@@](C)(O)CC2)nn2ccc(-c3ccc4nnn(CC(F)(F)F)c4c3)c12 |r,wU:9.9,wD:6.5,9.10,(-2.68,-.19,;-1.35,-.96,;-1.35,-2.5,;-.01,-3.27,;-.01,-4.81,;1.33,-5.56,;2.65,-4.78,;4.01,-5.51,;5.32,-4.78,;5.32,-3.24,;5.32,-1.7,;6.65,-2.46,;4.01,-2.5,;2.65,-3.24,;-1.35,-5.58,;-2.68,-4.81,;-4.14,-5.28,;-5.05,-4.04,;-4.14,-2.79,;-4.64,-1.33,;-6.15,-1.03,;-6.65,.42,;-5.63,1.58,;-5.82,3.11,;-4.42,3.76,;-3.37,2.63,;-1.84,2.81,;-1.24,4.23,;-.63,5.64,;.18,3.62,;-2.65,4.83,;-4.12,1.28,;-3.63,-.17,;-2.68,-3.27,)| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 7.70 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643639
(US20240002391, Compound 911)Show SMILES COc1nc(N[C@H]2CC[C@](C)(O)CC2)nn2ccc(-c3ccc4nnn(CC(F)(F)F)c4c3)c12 |r,wU:9.10,wD:6.5,9.9,(-2.68,-.19,;-1.35,-.96,;-1.35,-2.5,;-.01,-3.27,;-.01,-4.81,;1.33,-5.56,;2.65,-4.78,;4.01,-5.51,;5.32,-4.78,;5.32,-3.24,;5.32,-1.7,;6.65,-2.46,;4.01,-2.5,;2.65,-3.24,;-1.35,-5.58,;-2.68,-4.81,;-4.14,-5.28,;-5.05,-4.04,;-4.14,-2.79,;-4.64,-1.33,;-6.15,-1.03,;-6.65,.42,;-5.63,1.58,;-5.82,3.11,;-4.42,3.76,;-3.37,2.63,;-1.84,2.81,;-1.24,4.23,;-.63,5.64,;.18,3.62,;-2.65,4.83,;-4.12,1.28,;-3.63,-.17,;-2.68,-3.27,)| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643640
(US20240002391, Compound 912)Show SMILES COc1nc(N[C@@H]2CN(C[C@@H]2F)C(C)=O)nn2ccc(-c3ccc4nnn(CC(F)(F)F)c4c3)c12 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643641
(US20240002391, Compound 916)Show SMILES COc1nc(N[C@H]2CCN(C[C@H]2F)C(C)=O)nn2ccc(-c3ccc4nnn(CC(F)(F)F)c4c3)c12 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643642
(US20240002391, Compound 918)Show SMILES COc1nc(N[C@H]2CCN(C[C@H]2F)C2COC2)nn2ccc(-c3ccc4nnn(CC(F)(F)F)c4c3)c12 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643643
(US20240002391, Compound 921)Show SMILES COc1nc(N[C@@H]2CCN(CC2(F)F)C(C)=O)nn2ccc(-c3ccc4nnn(CC(F)(F)F)c4c3)c12 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643644
(US20240002391, Compound 922)Show SMILES COc1nc(N[C@@H]2CCN(CC2(F)F)C2COC2)nn2ccc(-c3ccc4nnn(CC(F)(F)F)c4c3)c12 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643645
(US20240002391, Compound 924)Show SMILES COc1nc(NCC(C)(C)F)nn2ccc(-c3cnc4nccn4c3)c12 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643646
(US20240002391, Compound 926)Show SMILES COCC[C@@H](C)Nc1nc(OC)c2c(ccn2n1)-c1cnc2nccn2c1 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 5.60 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643647
(US20240002391, Compound 927)Show SMILES COc1nc(N[C@H](C)C2COC2)nn2ccc(-c3cnc4nccn4c3)c12 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643648
(US20240002391, Compound 928)Show SMILES COc1nc(N[C@@H](C)C2COC2)nn2ccc(-c3cnc4nccn4c3)c12 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643649
(US20240002391, Compound 929)Show SMILES CO[C@H]1CC[C@H]1Nc1nc(OC)c2c(ccn2n1)-c1cnc2nccn2c1 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 19.8 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643650
(US20240002391, Compound 930)Show SMILES CO[C@@H]1CC[C@H]1Nc1nc(OC)c2c(ccn2n1)-c1cnc2nccn2c1 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 6.90 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643651
(US20240002391, Compound 931)Show SMILES CCO[C@@H]1C[C@@H](C1)Nc1nc(OC)c2c(ccn2n1)-c1cnc2nccn2c1 |r,wD:5.7,3.2,(8.12,-2.01,;6.79,-2.78,;5.45,-2.01,;4.12,-2.78,;3.7,-4.28,;2.21,-3.88,;2.61,-2.39,;.88,-4.65,;-.45,-3.88,;-.45,-2.34,;-1.79,-1.57,;-1.79,-.03,;-.45,.74,;-3.12,-2.34,;-4.58,-1.87,;-5.49,-3.11,;-4.58,-4.36,;-3.12,-3.88,;-1.79,-4.65,;-4.98,-.38,;-6.45,.1,;-6.77,1.6,;-5.62,2.64,;-5.62,4.18,;-4.16,4.65,;-3.25,3.41,;-4.16,2.16,;-3.84,.65,)| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643652
(US20240002391, Compound 934)Show SMILES COc1nc(N[C@H]2C[C@](C)(C2)NC(C)=O)nn2ccc(-c3cnc4nccn4c3)c12 |r,wU:8.8,wD:6.5,8.11,(-1.12,.74,;-2.45,-.03,;-2.45,-1.57,;-1.12,-2.34,;-1.12,-3.88,;.21,-4.65,;1.55,-3.88,;3.04,-4.28,;3.43,-2.79,;3.43,-1.25,;1.95,-2.39,;4.77,-2.02,;6.1,-2.79,;7.43,-2.02,;6.1,-4.33,;-2.45,-4.65,;-3.79,-3.88,;-5.25,-4.36,;-6.16,-3.11,;-5.25,-1.87,;-5.65,-.38,;-7.11,.1,;-7.43,1.6,;-6.29,2.64,;-6.29,4.18,;-4.83,4.65,;-3.92,3.41,;-4.83,2.16,;-4.51,.65,;-3.79,-2.34,)| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643653
(US20240002391, Compound 935)Show SMILES COc1nc(N[C@H]2C[C@@](C)(C2)NC(C)=O)nn2ccc(-c3cnc4nccn4c3)c12 |r,wU:8.11,wD:6.5,8.8,(-1.12,.74,;-2.45,-.03,;-2.45,-1.57,;-1.12,-2.34,;-1.12,-3.88,;.21,-4.65,;1.55,-3.88,;3.04,-4.28,;3.43,-2.79,;3.43,-1.25,;1.95,-2.39,;4.77,-2.02,;6.1,-2.79,;7.43,-2.02,;6.1,-4.33,;-2.45,-4.65,;-3.79,-3.88,;-5.25,-4.36,;-6.16,-3.11,;-5.25,-1.87,;-5.65,-.38,;-7.11,.1,;-7.43,1.6,;-6.29,2.64,;-6.29,4.18,;-4.83,4.65,;-3.92,3.41,;-4.83,2.16,;-4.51,.65,;-3.79,-2.34,)| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643654
(US20240002391, Compound 942)Show SMILES COc1nc(N[C@@H]2CCC[C@@H]2O)nn2ccc(-c3cnc4nccn4c3)c12 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 18.9 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643655
(US20240002391, Compound 943)Show SMILES COc1nc(N[C@@H]2CCC(F)(F)C2)nn2ccc(-c3cnc4nccn4c3)c12 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643656
(US20240002391, Compound 944) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643657
(US20240002391, Compound 947)Show SMILES COc1nc(NC2CCC(C)(C)CC2)nn2ccc(-c3cnc4nccn4c3)c12 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643658
(US20240002391, Compound 948)Show SMILES COc1nc(NC2CCC(C)(CC2)C#N)nn2ccc(-c3cnc4nccn4c3)c12 |(-1.95,-5.27,;-.62,-4.5,;-.62,-2.96,;.71,-2.19,;.71,-.65,;2.05,.12,;2.05,1.66,;.71,2.43,;.71,3.97,;2.05,4.74,;2.77,6.1,;3.38,3.97,;3.38,2.43,;1.32,6.1,;.6,7.46,;-.62,.12,;-1.95,-.65,;-3.42,-.17,;-4.32,-1.42,;-3.42,-2.67,;-3.9,-4.13,;-2.87,-5.28,;-3.34,-6.74,;-4.85,-7.06,;-5.62,-8.39,;-7.12,-8.07,;-7.28,-6.54,;-5.88,-5.92,;-5.4,-4.45,;-1.95,-2.19,)| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643659
(US20240002391, Compound 954)Show SMILES COc1nc(N[C@H]2CC[C@@](C)(CC2)OC)nn2ccc(-c3cnc4nccn4c3)c12 |r,wU:6.5,9.9,wD:9.13,(-2.38,-3.26,;-1.05,-2.49,;-1.05,-.95,;.28,-.18,;.28,1.36,;1.62,2.13,;2.95,1.36,;4.29,2.13,;5.62,1.36,;5.62,-.18,;7.16,-.23,;4.29,-.95,;2.95,-.18,;6.44,-1.48,;7.97,-1.43,;-1.05,2.13,;-2.38,1.36,;-3.85,1.84,;-4.75,.59,;-3.85,-.65,;-4.32,-2.12,;-3.29,-3.26,;-3.77,-4.73,;-5.27,-5.05,;-6.04,-6.38,;-7.55,-6.06,;-7.71,-4.53,;-6.31,-3.9,;-5.83,-2.44,;-2.38,-.18,)| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643660
(US20240002391, Compound 964)Show SMILES COc1nc(N[C@@H]2CCNCC2(F)F)nn2ccc(-c3cnc4nccn4c3)c12 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643661
(US20240002391, Compound 968)Show SMILES COc1nc(N[C@@H]2CCN(CC2(F)F)C2COC2)nn2ccc(-c3cnc4nccn4c3)c12 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643662
(US20240002391, Compound 975)Show SMILES COc1nc(N[C@@H]2CCCOC2)nn2ccc(-c3cnc4nccn4c3)c12 |r| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 7.60 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643663
(US20240002391, Compound 976)Show SMILES COc1nc(NC2CC3CC3C2)nn2ccc(-c3cnc4nccn4c3)c12 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643664
(US20240002391, Compound 977)Show SMILES COc1nc(NC2CCC3(CC3)CC2)nn2ccc(-c3cnc4nccn4c3)c12 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM643665
(US20240002391, Compound 978)Show SMILES COc1nc(NC23CCC(O)(CC2)C3)nn2ccc(-c3cnc4nccn4c3)c12 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |