Compile Data Set for Download or QSAR

Found 24 hits Enz. Inhib. hit(s) with all data for entry = 5671   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM92524 (Aminopyrazole inhibitor, 3576) Show SMILES COc1cc(NC(=O)c2cccc(c2)-n2cc(NC(=O)Nc3cccc(C)c3)cn2)cc(OC)c1OC Show InChI InChI=1S/C27H27N5O5/c1-17-7-5-9-19(11-17)30-27(34)31-21-15-28-32(16-21)22-10-6-8-18(12-22)26(33)29-20-13-23(35-2)25(37-4)24(14-20)36-3/h5-16H,1-4H3,(H,29,33)(H2,30,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	7.0	22
The Scripps Research Institute					Assay Description Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...				J Biol Chem 284: 12853-61 (2009) Article DOI: 10.1074/jbc.M809430200 BindingDB Entry DOI: 10.7270/Q2NZ867T
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM92523 (Aminopyrazole inhibitor, 3528) Show SMILES COc1cc(NC(=O)c2cccc(c2)-n2cc(NC(=O)Nc3ccccc3Cl)cn2)cc(OC)c1OC Show InChI InChI=1S/C26H24ClN5O5/c1-35-22-12-17(13-23(36-2)24(22)37-3)29-25(33)16-7-6-8-19(11-16)32-15-18(14-28-32)30-26(34)31-21-10-5-4-9-20(21)27/h4-15H,1-3H3,(H,29,33)(H2,30,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	7.0	22
The Scripps Research Institute					Assay Description Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...				J Biol Chem 284: 12853-61 (2009) Article DOI: 10.1074/jbc.M809430200 BindingDB Entry DOI: 10.7270/Q2NZ867T
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM92522 (Aminopyrazole inhibitor, 3451) Show SMILES COc1cc(NC(=O)c2cccc(c2)-n2cc(NC(=O)Nc3ccccc3)cn2)cc(OC)c1OC Show InChI InChI=1S/C26H25N5O5/c1-34-22-13-19(14-23(35-2)24(22)36-3)28-25(32)17-8-7-11-21(12-17)31-16-20(15-27-31)30-26(33)29-18-9-5-4-6-10-18/h4-16H,1-3H3,(H,28,32)(H2,29,30,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	7.0	22
The Scripps Research Institute					Assay Description Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...				J Biol Chem 284: 12853-61 (2009) Article DOI: 10.1074/jbc.M809430200 BindingDB Entry DOI: 10.7270/Q2NZ867T
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM92526 (Aminopyrazole inhibitor, 4326) Show SMILES Cc1cncc(NC(=O)c2cccc(c2)-n2cc(NC(=O)Nc3ccccc3Cl)cn2)c1 Show InChI InChI=1S/C23H19ClN6O2/c1-15-9-17(12-25-11-15)27-22(31)16-5-4-6-19(10-16)30-14-18(13-26-30)28-23(32)29-21-8-3-2-7-20(21)24/h2-14H,1H3,(H,27,31)(H2,28,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	7.0	22
The Scripps Research Institute					Assay Description Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...				J Biol Chem 284: 12853-61 (2009) Article DOI: 10.1074/jbc.M809430200 BindingDB Entry DOI: 10.7270/Q2NZ867T
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM92524 (Aminopyrazole inhibitor, 3576) Show SMILES COc1cc(NC(=O)c2cccc(c2)-n2cc(NC(=O)Nc3cccc(C)c3)cn2)cc(OC)c1OC Show InChI InChI=1S/C27H27N5O5/c1-17-7-5-9-19(11-17)30-27(34)31-21-15-28-32(16-21)22-10-6-8-18(12-22)26(33)29-20-13-23(35-2)25(37-4)24(14-20)36-3/h5-16H,1-4H3,(H,29,33)(H2,30,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	7.0	22
The Scripps Research Institute					Assay Description Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...				J Biol Chem 284: 12853-61 (2009) Article DOI: 10.1074/jbc.M809430200 BindingDB Entry DOI: 10.7270/Q2NZ867T
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM92530 (Aminopyrazole inhibitor, 4276) Show SMILES Clc1ccccc1NC(=O)Nc1cnn(c1)-c1cccc(c1)C(=O)NCCCN1CCOCC1 Show InChI InChI=1S/C24H27ClN6O3/c25-21-7-1-2-8-22(21)29-24(33)28-19-16-27-31(17-19)20-6-3-5-18(15-20)23(32)26-9-4-10-30-11-13-34-14-12-30/h1-3,5-8,15-17H,4,9-14H2,(H,26,32)(H2,28,29,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	7.0	22
The Scripps Research Institute					Assay Description Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...				J Biol Chem 284: 12853-61 (2009) Article DOI: 10.1074/jbc.M809430200 BindingDB Entry DOI: 10.7270/Q2NZ867T
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM92522 (Aminopyrazole inhibitor, 3451) Show SMILES COc1cc(NC(=O)c2cccc(c2)-n2cc(NC(=O)Nc3ccccc3)cn2)cc(OC)c1OC Show InChI InChI=1S/C26H25N5O5/c1-34-22-13-19(14-23(35-2)24(22)36-3)28-25(32)17-8-7-11-21(12-17)31-16-20(15-27-31)30-26(33)29-18-9-5-4-6-10-18/h4-16H,1-3H3,(H,28,32)(H2,29,30,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	7.0	22
The Scripps Research Institute					Assay Description Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...				J Biol Chem 284: 12853-61 (2009) Article DOI: 10.1074/jbc.M809430200 BindingDB Entry DOI: 10.7270/Q2NZ867T
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM92525 (Aminopyrazole inhibitor, 3583) Show SMILES COc1cc(NC(=O)c2cccc(c2)-n2cc(NC(=O)Nc3ccc(Cl)cc3)cn2)cc(OC)c1OC Show InChI InChI=1S/C26H24ClN5O5/c1-35-22-12-19(13-23(36-2)24(22)37-3)29-25(33)16-5-4-6-21(11-16)32-15-20(14-28-32)31-26(34)30-18-9-7-17(27)8-10-18/h4-15H,1-3H3,(H,29,33)(H2,30,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	7.0	22
The Scripps Research Institute					Assay Description Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...				J Biol Chem 284: 12853-61 (2009) Article DOI: 10.1074/jbc.M809430200 BindingDB Entry DOI: 10.7270/Q2NZ867T
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM92523 (Aminopyrazole inhibitor, 3528) Show SMILES COc1cc(NC(=O)c2cccc(c2)-n2cc(NC(=O)Nc3ccccc3Cl)cn2)cc(OC)c1OC Show InChI InChI=1S/C26H24ClN5O5/c1-35-22-12-17(13-23(36-2)24(22)37-3)29-25(33)16-7-6-8-19(11-16)32-15-18(14-28-32)30-26(34)31-21-10-5-4-9-20(21)27/h4-15H,1-3H3,(H,29,33)(H2,30,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	7.0	22
The Scripps Research Institute					Assay Description Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...				J Biol Chem 284: 12853-61 (2009) Article DOI: 10.1074/jbc.M809430200 BindingDB Entry DOI: 10.7270/Q2NZ867T
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM92526 (Aminopyrazole inhibitor, 4326) Show SMILES Cc1cncc(NC(=O)c2cccc(c2)-n2cc(NC(=O)Nc3ccccc3Cl)cn2)c1 Show InChI InChI=1S/C23H19ClN6O2/c1-15-9-17(12-25-11-15)27-22(31)16-5-4-6-19(10-16)30-14-18(13-26-30)28-23(32)29-21-8-3-2-7-20(21)24/h2-14H,1H3,(H,27,31)(H2,28,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	7.0	22
The Scripps Research Institute					Assay Description Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...				J Biol Chem 284: 12853-61 (2009) Article DOI: 10.1074/jbc.M809430200 BindingDB Entry DOI: 10.7270/Q2NZ867T
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM92528 (Aminopyrazole inhibitor, 4643) Show SMILES Cc1cncc(NC(=O)c2cc(cc(c2)-n2cc(NC(=O)Nc3ccccc3Cl)cn2)N2CCOCC2)c1 Show InChI InChI=1S/C27H26ClN7O3/c1-18-10-20(15-29-14-18)31-26(36)19-11-22(34-6-8-38-9-7-34)13-23(12-19)35-17-21(16-30-35)32-27(37)33-25-5-3-2-4-24(25)28/h2-5,10-17H,6-9H2,1H3,(H,31,36)(H2,32,33,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	7.0	22
The Scripps Research Institute					Assay Description Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...				J Biol Chem 284: 12853-61 (2009) Article DOI: 10.1074/jbc.M809430200 BindingDB Entry DOI: 10.7270/Q2NZ867T
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM92529 (Aminopyrazole inhibitor, 4018) Show SMILES Cc1cccc(NC(=O)Nc2cnn(c2)-c2cccc(c2)C(=O)NCCN2CCOCC2)c1 Show InChI InChI=1S/C24H28N6O3/c1-18-4-2-6-20(14-18)27-24(32)28-21-16-26-30(17-21)22-7-3-5-19(15-22)23(31)25-8-9-29-10-12-33-13-11-29/h2-7,14-17H,8-13H2,1H3,(H,25,31)(H2,27,28,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	7.0	22
The Scripps Research Institute					Assay Description Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...				J Biol Chem 284: 12853-61 (2009) Article DOI: 10.1074/jbc.M809430200 BindingDB Entry DOI: 10.7270/Q2NZ867T
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM92527 (Aminopyrazole inhibitor, 4642) Show SMILES CN(C)c1cc(cc(c1)-n1cc(NC(=O)Nc2ccccc2Cl)cn1)C(=O)Nc1cncc(C)c1 Show InChI InChI=1S/C25H24ClN7O2/c1-16-8-18(13-27-12-16)29-24(34)17-9-20(32(2)3)11-21(10-17)33-15-19(14-28-33)30-25(35)31-23-7-5-4-6-22(23)26/h4-15H,1-3H3,(H,29,34)(H2,30,31,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	7.0	22
The Scripps Research Institute					Assay Description Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...				J Biol Chem 284: 12853-61 (2009) Article DOI: 10.1074/jbc.M809430200 BindingDB Entry DOI: 10.7270/Q2NZ867T
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 13 (Homo sapiens (Human))	BDBM92522 (Aminopyrazole inhibitor, 3451) Show SMILES COc1cc(NC(=O)c2cccc(c2)-n2cc(NC(=O)Nc3ccccc3)cn2)cc(OC)c1OC Show InChI InChI=1S/C26H25N5O5/c1-34-22-13-19(14-23(35-2)24(22)36-3)28-25(32)17-8-7-11-21(12-17)31-16-20(15-27-31)30-26(33)29-18-9-5-4-6-10-18/h4-16H,1-3H3,(H,28,32)(H2,29,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	7.0	22
The Scripps Research Institute					Assay Description Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...				J Biol Chem 284: 12853-61 (2009) Article DOI: 10.1074/jbc.M809430200 BindingDB Entry DOI: 10.7270/Q2NZ867T
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 13 (Homo sapiens (Human))	BDBM92529 (Aminopyrazole inhibitor, 4018) Show SMILES Cc1cccc(NC(=O)Nc2cnn(c2)-c2cccc(c2)C(=O)NCCN2CCOCC2)c1 Show InChI InChI=1S/C24H28N6O3/c1-18-4-2-6-20(14-18)27-24(32)28-21-16-26-30(17-21)22-7-3-5-19(15-22)23(31)25-8-9-29-10-12-33-13-11-29/h2-7,14-17H,8-13H2,1H3,(H,25,31)(H2,27,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	7.0	22
The Scripps Research Institute					Assay Description Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...				J Biol Chem 284: 12853-61 (2009) Article DOI: 10.1074/jbc.M809430200 BindingDB Entry DOI: 10.7270/Q2NZ867T
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 13 (Homo sapiens (Human))	BDBM92528 (Aminopyrazole inhibitor, 4643) Show SMILES Cc1cncc(NC(=O)c2cc(cc(c2)-n2cc(NC(=O)Nc3ccccc3Cl)cn2)N2CCOCC2)c1 Show InChI InChI=1S/C27H26ClN7O3/c1-18-10-20(15-29-14-18)31-26(36)19-11-22(34-6-8-38-9-7-34)13-23(12-19)35-17-21(16-30-35)32-27(37)33-25-5-3-2-4-24(25)28/h2-5,10-17H,6-9H2,1H3,(H,31,36)(H2,32,33,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	7.0	22
The Scripps Research Institute					Assay Description Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...				J Biol Chem 284: 12853-61 (2009) Article DOI: 10.1074/jbc.M809430200 BindingDB Entry DOI: 10.7270/Q2NZ867T
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 13 (Homo sapiens (Human))	BDBM92527 (Aminopyrazole inhibitor, 4642) Show SMILES CN(C)c1cc(cc(c1)-n1cc(NC(=O)Nc2ccccc2Cl)cn1)C(=O)Nc1cncc(C)c1 Show InChI InChI=1S/C25H24ClN7O2/c1-16-8-18(13-27-12-16)29-24(34)17-9-20(32(2)3)11-21(10-17)33-15-19(14-28-33)30-25(35)31-23-7-5-4-6-22(23)26/h4-15H,1-3H3,(H,29,34)(H2,30,31,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	7.0	22
The Scripps Research Institute					Assay Description Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...				J Biol Chem 284: 12853-61 (2009) Article DOI: 10.1074/jbc.M809430200 BindingDB Entry DOI: 10.7270/Q2NZ867T
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 13 (Homo sapiens (Human))	BDBM92526 (Aminopyrazole inhibitor, 4326) Show SMILES Cc1cncc(NC(=O)c2cccc(c2)-n2cc(NC(=O)Nc3ccccc3Cl)cn2)c1 Show InChI InChI=1S/C23H19ClN6O2/c1-15-9-17(12-25-11-15)27-22(31)16-5-4-6-19(10-16)30-14-18(13-26-30)28-23(32)29-21-8-3-2-7-20(21)24/h2-14H,1H3,(H,27,31)(H2,28,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	7.0	22
The Scripps Research Institute					Assay Description Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...				J Biol Chem 284: 12853-61 (2009) Article DOI: 10.1074/jbc.M809430200 BindingDB Entry DOI: 10.7270/Q2NZ867T
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 13 (Homo sapiens (Human))	BDBM92524 (Aminopyrazole inhibitor, 3576) Show SMILES COc1cc(NC(=O)c2cccc(c2)-n2cc(NC(=O)Nc3cccc(C)c3)cn2)cc(OC)c1OC Show InChI InChI=1S/C27H27N5O5/c1-17-7-5-9-19(11-17)30-27(34)31-21-15-28-32(16-21)22-10-6-8-18(12-22)26(33)29-20-13-23(35-2)25(37-4)24(14-20)36-3/h5-16H,1-4H3,(H,29,33)(H2,30,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	7.0	22
The Scripps Research Institute					Assay Description Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...				J Biol Chem 284: 12853-61 (2009) Article DOI: 10.1074/jbc.M809430200 BindingDB Entry DOI: 10.7270/Q2NZ867T
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 13 (Homo sapiens (Human))	BDBM92523 (Aminopyrazole inhibitor, 3528) Show SMILES COc1cc(NC(=O)c2cccc(c2)-n2cc(NC(=O)Nc3ccccc3Cl)cn2)cc(OC)c1OC Show InChI InChI=1S/C26H24ClN5O5/c1-35-22-12-17(13-23(36-2)24(22)37-3)29-25(33)16-7-6-8-19(11-16)32-15-18(14-28-32)30-26(34)31-21-10-5-4-9-20(21)27/h4-15H,1-3H3,(H,29,33)(H2,30,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	7.0	22
The Scripps Research Institute					Assay Description Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...				J Biol Chem 284: 12853-61 (2009) Article DOI: 10.1074/jbc.M809430200 BindingDB Entry DOI: 10.7270/Q2NZ867T
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM92529 (Aminopyrazole inhibitor, 4018) Show SMILES Cc1cccc(NC(=O)Nc2cnn(c2)-c2cccc(c2)C(=O)NCCN2CCOCC2)c1 Show InChI InChI=1S/C24H28N6O3/c1-18-4-2-6-20(14-18)27-24(32)28-21-16-26-30(17-21)22-7-3-5-19(15-22)23(31)25-8-9-29-10-12-33-13-11-29/h2-7,14-17H,8-13H2,1H3,(H,25,31)(H2,27,28,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	7.0	22
The Scripps Research Institute					Assay Description Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...				J Biol Chem 284: 12853-61 (2009) Article DOI: 10.1074/jbc.M809430200 BindingDB Entry DOI: 10.7270/Q2NZ867T
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM92527 (Aminopyrazole inhibitor, 4642) Show SMILES CN(C)c1cc(cc(c1)-n1cc(NC(=O)Nc2ccccc2Cl)cn1)C(=O)Nc1cncc(C)c1 Show InChI InChI=1S/C25H24ClN7O2/c1-16-8-18(13-27-12-16)29-24(34)17-9-20(32(2)3)11-21(10-17)33-15-19(14-28-33)30-25(35)31-23-7-5-4-6-22(23)26/h4-15H,1-3H3,(H,29,34)(H2,30,31,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	7.0	22
The Scripps Research Institute					Assay Description Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...				J Biol Chem 284: 12853-61 (2009) Article DOI: 10.1074/jbc.M809430200 BindingDB Entry DOI: 10.7270/Q2NZ867T
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 13 (Homo sapiens (Human))	BDBM92530 (Aminopyrazole inhibitor, 4276) Show SMILES Clc1ccccc1NC(=O)Nc1cnn(c1)-c1cccc(c1)C(=O)NCCCN1CCOCC1 Show InChI InChI=1S/C24H27ClN6O3/c25-21-7-1-2-8-22(21)29-24(33)28-19-16-27-31(17-19)20-6-3-5-18(15-20)23(32)26-9-4-10-30-11-13-34-14-12-30/h1-3,5-8,15-17H,4,9-14H2,(H,26,32)(H2,28,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	7.0	22
The Scripps Research Institute					Assay Description Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...				J Biol Chem 284: 12853-61 (2009) Article DOI: 10.1074/jbc.M809430200 BindingDB Entry DOI: 10.7270/Q2NZ867T
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM92528 (Aminopyrazole inhibitor, 4643) Show SMILES Cc1cncc(NC(=O)c2cc(cc(c2)-n2cc(NC(=O)Nc3ccccc3Cl)cn2)N2CCOCC2)c1 Show InChI InChI=1S/C27H26ClN7O3/c1-18-10-20(15-29-14-18)31-26(36)19-11-22(34-6-8-38-9-7-34)13-23(12-19)35-17-21(16-30-35)32-27(37)33-25-5-3-2-4-24(25)28/h2-5,10-17H,6-9H2,1H3,(H,31,36)(H2,32,33,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	7.0	22
The Scripps Research Institute					Assay Description Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...				J Biol Chem 284: 12853-61 (2009) Article DOI: 10.1074/jbc.M809430200 BindingDB Entry DOI: 10.7270/Q2NZ867T
					More data for this Ligand-Target Pair