Compile Data Set for Download or QSAR

Found 31 hits Enz. Inhib. hit(s) with all data for entry = 6249   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119458 (US8680120, 9-32) Show SMILES COc1ccc2n(Cc3cccc(c3)C(O)=O)c(cc2c1)-c1ccoc1 Show InChI InChI=1S/C21H17NO4/c1-25-18-5-6-19-17(10-18)11-20(16-7-8-26-13-16)22(19)12-14-3-2-4-15(9-14)21(23)24/h2-11,13H,12H2,1H3,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Fluo-4 NW Calcium Assay Kit ...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119460 (US8680120, 9-43) Show SMILES COc1cc2cc(-c3ccccc3)n(Cc3cccc(c3)C(O)=O)c2cc1F Show InChI InChI=1S/C23H18FNO3/c1-28-22-12-18-11-20(16-7-3-2-4-8-16)25(21(18)13-19(22)24)14-15-6-5-9-17(10-15)23(26)27/h2-13H,14H2,1H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Fluo-4 NW Calcium Assay Kit ...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119456 (US8680120, 9-21) Show SMILES COc1ccc2n(Cc3cccc(n3)C(O)=O)c(cc2c1)-c1ccccc1 Show InChI InChI=1S/C22H18N2O3/c1-27-18-10-11-20-16(12-18)13-21(15-6-3-2-4-7-15)24(20)14-17-8-5-9-19(23-17)22(25)26/h2-13H,14H2,1H3,(H,25,26)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Fluo-4 NW Calcium Assay Kit ...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119471 (US8680120, 25-26) Show SMILES COc1cc2cc(-c3ccccc3)n(Cc3ccc(o3)C(O)=O)c2cc1Cl Show InChI InChI=1S/C21H16ClNO4/c1-26-20-10-14-9-17(13-5-3-2-4-6-13)23(18(14)11-16(20)22)12-15-7-8-19(27-15)21(24)25/h2-11H,12H2,1H3,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119468 (US8680120, 25-18) Show SMILES COc1ccc2n(Cc3cccc(c3)C(O)=O)c(cc2c1)-c1cccc(F)c1 Show InChI InChI=1S/C23H18FNO3/c1-28-20-8-9-21-18(12-20)13-22(16-5-3-7-19(24)11-16)25(21)14-15-4-2-6-17(10-15)23(26)27/h2-13H,14H2,1H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119461 (US8680120, 9-44) Show SMILES COc1ccc2n(Cc3cccc(C(O)=O)c3F)c(cc2c1)-c1ccccc1 Show InChI InChI=1S/C23H18FNO3/c1-28-18-10-11-20-17(12-18)13-21(15-6-3-2-4-7-15)25(20)14-16-8-5-9-19(22(16)24)23(26)27/h2-13H,14H2,1H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Fluo-4 NW Calcium Assay Kit ...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119453 (US8680120, 9-1) Show SMILES COc1ccc2n(Cc3cccc(c3)C(O)=O)c(cc2c1)-c1ccccc1 Show InChI InChI=1S/C23H19NO3/c1-27-20-10-11-21-19(13-20)14-22(17-7-3-2-4-8-17)24(21)15-16-6-5-9-18(12-16)23(25)26/h2-14H,15H2,1H3,(H,25,26)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Fluo-4 NW Calcium Assay Kit ...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119455 (US8680120, 9-15) Show SMILES COc1ccc2n(Cc3cccc(c3)C(O)=O)c(cc2c1)C(C)C Show InChI InChI=1S/C20H21NO3/c1-13(2)19-11-16-10-17(24-3)7-8-18(16)21(19)12-14-5-4-6-15(9-14)20(22)23/h4-11,13H,12H2,1-3H3,(H,22,23)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Fluo-4 NW Calcium Assay Kit ...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119479 (US8680120, 25-38) Show SMILES COc1cc2cc(-c3ccoc3)n(Cc3ccc(o3)C(O)=O)c2cc1Cl Show InChI InChI=1S/C19H14ClNO5/c1-24-18-7-12-6-15(11-4-5-25-10-11)21(16(12)8-14(18)20)9-13-2-3-17(26-13)19(22)23/h2-8,10H,9H2,1H3,(H,22,23)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119459 (US8680120, 9-35) Show SMILES COc1ccc2n(Cc3cccc(n3)C(O)=O)c(cc2c1)-c1ccsc1 Show InChI InChI=1S/C20H16N2O3S/c1-25-16-5-6-18-14(9-16)10-19(13-7-8-26-12-13)22(18)11-15-3-2-4-17(21-15)20(23)24/h2-10,12H,11H2,1H3,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Fluo-4 NW Calcium Assay Kit ...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119481 (US8680120, 25-41) Show SMILES COc1ccc2n(Cc3cccc(n3)C(O)=O)c(cc2c1)-c1cc(F)ccc1F Show InChI InChI=1S/C22H16F2N2O3/c1-29-16-6-8-20-13(9-16)10-21(17-11-14(23)5-7-18(17)24)26(20)12-15-3-2-4-19(25-15)22(27)28/h2-11H,12H2,1H3,(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119473 (US8680120, 25-29) Show SMILES COc1cc2cc(-c3cccc(F)c3)n(Cc3cccc(n3)C(O)=O)c2cc1F Show InChI InChI=1S/C22H16F2N2O3/c1-29-21-10-14-9-19(13-4-2-5-15(23)8-13)26(20(14)11-17(21)24)12-16-6-3-7-18(25-16)22(27)28/h2-11H,12H2,1H3,(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119478 (US8680120, 25-37) Show SMILES COc1cc2cc(-c3ccoc3)n(Cc3cccc(n3)C(O)=O)c2cc1Cl Show InChI InChI=1S/C20H15ClN2O4/c1-26-19-8-13-7-17(12-5-6-27-11-12)23(18(13)9-15(19)21)10-14-3-2-4-16(22-14)20(24)25/h2-9,11H,10H2,1H3,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119482 (US8680120, 25-42) Show SMILES COc1cc2cc(-c3cccnc3)n(Cc3cccc(n3)C(O)=O)c2cc1Cl Show InChI InChI=1S/C21H16ClN3O3/c1-28-20-9-14-8-18(13-4-3-7-23-11-13)25(19(14)10-16(20)22)12-15-5-2-6-17(24-15)21(26)27/h2-11H,12H2,1H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119472 (US8680120, 25-28) Show SMILES COc1cc2cc(-c3ccccc3F)n(Cc3cccc(n3)C(O)=O)c2cc1F Show InChI InChI=1S/C22H16F2N2O3/c1-29-21-10-13-9-20(15-6-2-3-7-16(15)23)26(19(13)11-17(21)24)12-14-5-4-8-18(25-14)22(27)28/h2-11H,12H2,1H3,(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119467 (US8680120, 25-17) Show SMILES COc1ccc2n(Cc3cccc(c3)C(O)=O)c(cc2c1)-c1ccccc1F Show InChI InChI=1S/C23H18FNO3/c1-28-18-9-10-21-17(12-18)13-22(19-7-2-3-8-20(19)24)25(21)14-15-5-4-6-16(11-15)23(26)27/h2-13H,14H2,1H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119470 (US8680120, 25-23) Show SMILES COc1cc2cc(-c3cccc(F)c3)n(Cc3cccc(n3)C(O)=O)c2cc1Cl Show InChI InChI=1S/C22H16ClFN2O3/c1-29-21-10-14-9-19(13-4-2-5-15(24)8-13)26(20(14)11-17(21)23)12-16-6-3-7-18(25-16)22(27)28/h2-11H,12H2,1H3,(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119474 (US8680120, 25-31) Show SMILES COc1cc2cc(-c3ccc(F)cc3)n(Cc3cccc(n3)C(O)=O)c2cc1F Show InChI InChI=1S/C22H16F2N2O3/c1-29-21-10-14-9-19(13-5-7-15(23)8-6-13)26(20(14)11-17(21)24)12-16-3-2-4-18(25-16)22(27)28/h2-11H,12H2,1H3,(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119463 (US8680120, 25-11) Show SMILES COc1ccc2n(Cc3ccc(o3)C(O)=O)c(cc2c1)-c1cccc(F)c1 Show InChI InChI=1S/C21H16FNO4/c1-26-16-5-7-18-14(10-16)11-19(13-3-2-4-15(22)9-13)23(18)12-17-6-8-20(27-17)21(24)25/h2-11H,12H2,1H3,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119457 (US8680120, 9-25) Show SMILES COc1ccc2n(Cc3cccc(c3)C(O)=O)c(cc2c1)-c1ccsc1 Show InChI InChI=1S/C21H17NO3S/c1-25-18-5-6-19-17(10-18)11-20(16-7-8-26-13-16)22(19)12-14-3-2-4-15(9-14)21(23)24/h2-11,13H,12H2,1H3,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Fluo-4 NW Calcium Assay Kit ...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119477 (US8680120, 25-36) Show SMILES COc1cc2cc(-c3ccccc3)n(Cc3ccc(o3)C(O)=O)c2cc1C Show InChI InChI=1S/C22H19NO4/c1-14-10-18-16(12-21(14)26-2)11-19(15-6-4-3-5-7-15)23(18)13-17-8-9-20(27-17)22(24)25/h3-12H,13H2,1-2H3,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119469 (US8680120, 25-19) Show SMILES COc1ccc2n(Cc3cccc(c3)C(O)=O)c(cc2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C23H18FNO3/c1-28-20-9-10-21-18(12-20)13-22(16-5-7-19(24)8-6-16)25(21)14-15-3-2-4-17(11-15)23(26)27/h2-13H,14H2,1H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119480 (US8680120, 25-39) Show SMILES COc1cc2cc(-c3ccsc3)n(Cc3cccc(n3)C(O)=O)c2cc1C Show InChI InChI=1S/C21H18N2O3S/c1-13-8-18-15(10-20(13)26-2)9-19(14-6-7-27-12-14)23(18)11-16-4-3-5-17(22-16)21(24)25/h3-10,12H,11H2,1-2H3,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119465 (US8680120, 25-13) Show SMILES COc1ccc2n(Cc3cccc(c3)C(O)=O)c(cc2c1)-c1cccnc1 Show InChI InChI=1S/C22H18N2O3/c1-27-19-7-8-20-18(11-19)12-21(17-6-3-9-23-13-17)24(20)14-15-4-2-5-16(10-15)22(25)26/h2-13H,14H2,1H3,(H,25,26)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119466 (US8680120, 25-16) Show SMILES COc1cc2cc(-c3ccccc3)n(Cc3cccc(n3)C(O)=O)c2cc1C Show InChI InChI=1S/C23H20N2O3/c1-15-11-20-17(13-22(15)28-2)12-21(16-7-4-3-5-8-16)25(20)14-18-9-6-10-19(24-18)23(26)27/h3-13H,14H2,1-2H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119483 (US8680120, 25-44) Show SMILES CCC(C)c1cc2cc(OC)c(Cl)cc2n1Cc1cccc(n1)C(O)=O Show InChI InChI=1S/C20H21ClN2O3/c1-4-12(2)17-8-13-9-19(26-3)15(21)10-18(13)23(17)11-14-6-5-7-16(22-14)20(24)25/h5-10,12H,4,11H2,1-3H3,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119476 (US8680120, 25-34) Show SMILES COc1cc2cc(-c3ccsc3)n(Cc3cccc(n3)C(O)=O)c2cc1Cl Show InChI InChI=1S/C20H15ClN2O3S/c1-26-19-8-13-7-17(12-5-6-27-11-12)23(18(13)9-15(19)21)10-14-3-2-4-16(22-14)20(24)25/h2-9,11H,10H2,1H3,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119464 (US8680120, 25-12) Show SMILES COc1ccc2n(Cc3csc(n3)C(O)=O)c(cc2c1)-c1ccccc1 Show InChI InChI=1S/C20H16N2O3S/c1-25-16-7-8-17-14(9-16)10-18(13-5-3-2-4-6-13)22(17)11-15-12-26-19(21-15)20(23)24/h2-10,12H,11H2,1H3,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119475 (US8680120, 25-33) Show SMILES COc1cc2cc(-c3cccnc3)n(Cc3cccc(n3)C(O)=O)c2cc1F Show InChI InChI=1S/C21H16FN3O3/c1-28-20-9-14-8-18(13-4-3-7-23-11-13)25(19(14)10-16(20)22)12-15-5-2-6-17(24-15)21(26)27/h2-11H,12H2,1H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119462 (US8680120, 25-9) Show SMILES COc1cc2cc(-c3ccccc3)n(Cc3cccc(n3)C(O)=O)c2cc1Cl Show InChI InChI=1S/C22H17ClN2O3/c1-28-21-11-15-10-19(14-6-3-2-4-7-14)25(20(15)12-17(21)23)13-16-8-5-9-18(24-16)22(26)27/h2-12H,13H2,1H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Calcium kit II, Fluo 4 (Doji...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Rattus norvegicus (Rat))	BDBM119454 (US8680120, 9-13) Show SMILES Cc1ccc2n(Cc3cccc(c3)C(O)=O)c(cc2c1)-c1ccccc1 Show InChI InChI=1S/C23H19NO2/c1-16-10-11-21-20(12-16)14-22(18-7-3-2-4-8-18)24(21)15-17-6-5-9-19(13-17)23(25)26/h2-14H,15H2,1H3,(H,25,26)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. US Patent					Assay Description The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Fluo-4 NW Calcium Assay Kit ...				US Patent US8680120 (2014) BindingDB Entry DOI: 10.7270/Q2183554
					More data for this Ligand-Target Pair