Compile Data Set for Download or QSAR

Found 93 hits Enz. Inhib. hit(s) with all data for entry = 7099   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174187 (US9102637, 222) Show SMILES NC1CCN(Cc2ccc(cc2)C(=O)Nc2sc(Nc3ccc4ccccc4c3)nc2C(N)=O)CC1 Show InChI InChI=1S/C27H28N6O2S/c28-21-11-13-33(14-12-21)16-17-5-7-19(8-6-17)25(35)32-26-23(24(29)34)31-27(36-26)30-22-10-9-18-3-1-2-4-20(18)15-22/h1-10,15,21H,11-14,16,28H2,(H2,29,34)(H,30,31)(H,32,35)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174104 (US9102637, 139) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6](=O)-[#7]-c1sc(-[#7]-c2ccc3cc(-[#6]-[#8])ccc3c2)nc1-[#6](-[#7])=O Show InChI InChI=1S/C20H20N4O3S/c1-11(2)7-16(26)23-19-17(18(21)27)24-20(28-19)22-15-6-5-13-8-12(10-25)3-4-14(13)9-15/h3-9,25H,10H2,1-2H3,(H2,21,27)(H,22,24)(H,23,26)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174202 (US9102637, 237) Show SMILES Cc1nccn1Cc1ccc(cc1)C(=O)Nc1sc(Nc2ccc3ccccc3c2)nc1C(N)=O Show InChI InChI=1S/C26H22N6O2S/c1-16-28-12-13-32(16)15-17-6-8-19(9-7-17)24(34)31-25-22(23(27)33)30-26(35-25)29-21-11-10-18-4-2-3-5-20(18)14-21/h2-14H,15H2,1H3,(H2,27,33)(H,29,30)(H,31,34)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174160 (US9102637, 195) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(Cn2cncn2)cc1 Show InChI InChI=1S/C24H19N7O2S/c25-21(32)20-23(30-22(33)17-7-5-15(6-8-17)12-31-14-26-13-27-31)34-24(29-20)28-19-10-9-16-3-1-2-4-18(16)11-19/h1-11,13-14H,12H2,(H2,25,32)(H,28,29)(H,30,33)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174186 (US9102637, 221) Show SMILES CN(C)[C@H]1CCN(Cc2ccc(cc2)C(=O)Nc2sc(Nc3ccc4ccccc4c3)nc2C(N)=O)C1 |r| Show InChI InChI=1S/C28H30N6O2S/c1-33(2)23-13-14-34(17-23)16-18-7-9-20(10-8-18)26(36)32-27-24(25(29)35)31-28(37-27)30-22-12-11-19-5-3-4-6-21(19)15-22/h3-12,15,23H,13-14,16-17H2,1-2H3,(H2,29,35)(H,30,31)(H,32,36)/t23-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174150 (US9102637, 185) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(CN2CCN(CCO)CC2)cc1 Show InChI InChI=1S/C28H30N6O3S/c29-25(36)24-27(38-28(31-24)30-23-10-9-20-3-1-2-4-22(20)17-23)32-26(37)21-7-5-19(6-8-21)18-34-13-11-33(12-14-34)15-16-35/h1-10,17,35H,11-16,18H2,(H2,29,36)(H,30,31)(H,32,37)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174196 (US9102637, 231) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(Cc2nn[nH]n2)cc1 Show InChI InChI=1S/C23H18N8O2S/c24-20(32)19-22(27-21(33)15-7-5-13(6-8-15)11-18-28-30-31-29-18)34-23(26-19)25-17-10-9-14-3-1-2-4-16(14)12-17/h1-10,12H,11H2,(H2,24,32)(H,25,26)(H,27,33)(H,28,29,30,31)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174185 (US9102637, 220) Show SMILES N[C@H]1CCN(Cc2ccc(cc2)C(=O)Nc2sc(Nc3ccc4ccccc4c3)nc2C(N)=O)C1 |r| Show InChI InChI=1S/C26H26N6O2S/c27-20-11-12-32(15-20)14-16-5-7-18(8-6-16)24(34)31-25-22(23(28)33)30-26(35-25)29-21-10-9-17-3-1-2-4-19(17)13-21/h1-10,13,20H,11-12,14-15,27H2,(H2,28,33)(H,29,30)(H,31,34)/t20-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174215 (US9102637, 250) Show SMILES NC(=O)c1nc(Nc2ccc3ncccc3c2)sc1NC(=O)c1ccc(Cn2ccnc2)cc1 Show InChI InChI=1S/C24H19N7O2S/c25-21(32)20-23(30-22(33)16-5-3-15(4-6-16)13-31-11-10-26-14-31)34-24(29-20)28-18-7-8-19-17(12-18)2-1-9-27-19/h1-12,14H,13H2,(H2,25,32)(H,28,29)(H,30,33)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174173 (US9102637, 208) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(Cn2ccnc2)cc1 Show InChI InChI=1S/C25H20N6O2S/c26-22(32)21-24(30-23(33)18-7-5-16(6-8-18)14-31-12-11-27-15-31)34-25(29-21)28-20-10-9-17-3-1-2-4-19(17)13-20/h1-13,15H,14H2,(H2,26,32)(H,28,29)(H,30,33)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174203 (US9102637, 238) Show SMILES Cc1cn(Cc2ccc(cc2)C(=O)Nc2sc(Nc3ccc4ccccc4c3)nc2C(N)=O)cn1 Show InChI InChI=1S/C26H22N6O2S/c1-16-13-32(15-28-16)14-17-6-8-19(9-7-17)24(34)31-25-22(23(27)33)30-26(35-25)29-21-11-10-18-4-2-3-5-20(18)12-21/h2-13,15H,14H2,1H3,(H2,27,33)(H,29,30)(H,31,34)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.10	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174155 (US9102637, 190) Show SMILES CN1CCCN(Cc2ccc(cc2)C(=O)Nc2sc(Nc3ccc4ccccc4c3)nc2C(N)=O)CC1 Show InChI InChI=1S/C28H30N6O2S/c1-33-13-4-14-34(16-15-33)18-19-7-9-21(10-8-19)26(36)32-27-24(25(29)35)31-28(37-27)30-23-12-11-20-5-2-3-6-22(20)17-23/h2-3,5-12,17H,4,13-16,18H2,1H3,(H2,29,35)(H,30,31)(H,32,36)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.20	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174138 (US9102637, 173) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(CN2CCC(O)CC2)cc1 Show InChI InChI=1S/C27H27N5O3S/c28-24(34)23-26(36-27(30-23)29-21-10-9-18-3-1-2-4-20(18)15-21)31-25(35)19-7-5-17(6-8-19)16-32-13-11-22(33)12-14-32/h1-10,15,22,33H,11-14,16H2,(H2,28,34)(H,29,30)(H,31,35)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.40	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174211 (US9102637, 246) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(Cn2cnc(CO)c2)cc1 Show InChI InChI=1S/C26H22N6O3S/c27-23(34)22-25(36-26(30-22)29-20-10-9-17-3-1-2-4-19(17)11-20)31-24(35)18-7-5-16(6-8-18)12-32-13-21(14-33)28-15-32/h1-11,13,15,33H,12,14H2,(H2,27,34)(H,29,30)(H,31,35)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174128 (US9102637, 163) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(CNCCO)cc1 Show InChI InChI=1S/C24H23N5O3S/c25-21(31)20-23(29-22(32)17-7-5-15(6-8-17)14-26-11-12-30)33-24(28-20)27-19-10-9-16-3-1-2-4-18(16)13-19/h1-10,13,26,30H,11-12,14H2,(H2,25,31)(H,27,28)(H,29,32)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.70	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174190 (US9102637, 225) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)C#CCCO Show InChI InChI=1S/C19H16N4O3S/c20-17(26)16-18(22-15(25)7-3-4-10-24)27-19(23-16)21-14-9-8-12-5-1-2-6-13(12)11-14/h1-2,5-6,8-9,11,24H,4,10H2,(H2,20,26)(H,21,23)(H,22,25)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM173989 (US9102637, 24) Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1sc(Nc2ccc3ncccc3c2)nc1C(N)=O Show InChI InChI=1S/C25H25N7O2S/c1-31-11-13-32(14-12-31)19-7-4-16(5-8-19)23(34)30-24-21(22(26)33)29-25(35-24)28-18-6-9-20-17(15-18)3-2-10-27-20/h2-10,15H,11-14H2,1H3,(H2,26,33)(H,28,29)(H,30,34)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.10	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174145 (US9102637, 180) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(CN2CCNC(=O)C2)cc1 Show InChI InChI=1S/C26H24N6O3S/c27-23(34)22-25(36-26(30-22)29-20-10-9-17-3-1-2-4-19(17)13-20)31-24(35)18-7-5-16(6-8-18)14-32-12-11-28-21(33)15-32/h1-10,13H,11-12,14-15H2,(H2,27,34)(H,28,33)(H,29,30)(H,31,35)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.20	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174130 (US9102637, 165) Show SMILES CC#CC(=O)Nc1sc(Nc2ccc3ccccc3c2)nc1C(N)=O Show InChI InChI=1S/C18H14N4O2S/c1-2-5-14(23)21-17-15(16(19)24)22-18(25-17)20-13-9-8-11-6-3-4-7-12(11)10-13/h3-4,6-10H,1H3,(H2,19,24)(H,20,22)(H,21,23)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.40	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174183 (US9102637, 218) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)C#CCO Show InChI InChI=1S/C18H14N4O3S/c19-16(25)15-17(21-14(24)6-3-9-23)26-18(22-15)20-13-8-7-11-4-1-2-5-12(11)10-13/h1-2,4-5,7-8,10,23H,9H2,(H2,19,25)(H,20,22)(H,21,24)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.5	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174219 (US9102637, 254) Show SMILES NC(=O)c1nc(Nc2cccc3ncccc23)sc1NC(=O)c1ccc(Cn2ccnc2)cc1 Show InChI InChI=1S/C24H19N7O2S/c25-21(32)20-23(30-22(33)16-8-6-15(7-9-16)13-31-12-11-26-14-31)34-24(29-20)28-19-5-1-4-18-17(19)3-2-10-27-18/h1-12,14H,13H2,(H2,25,32)(H,28,29)(H,30,33)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.80	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174168 (US9102637, 203) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(CN2CC[C@H](O)C2)cc1 |r| Show InChI InChI=1S/C26H25N5O3S/c27-23(33)22-25(35-26(29-22)28-20-10-9-17-3-1-2-4-19(17)13-20)30-24(34)18-7-5-16(6-8-18)14-31-12-11-21(32)15-31/h1-10,13,21,32H,11-12,14-15H2,(H2,27,33)(H,28,29)(H,30,34)/t21-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM173982 (US9102637, 17) Show SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2sc(Nc3ccc4ccccc4c3)nc2C(N)=O)CC1 Show InChI InChI=1S/C27H28N6O2S/c1-32-12-14-33(15-13-32)17-18-6-8-20(9-7-18)25(35)31-26-23(24(28)34)30-27(36-26)29-22-11-10-19-4-2-3-5-21(19)16-22/h2-11,16H,12-15,17H2,1H3,(H2,28,34)(H,29,30)(H,31,35)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.10	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174225 (US9102637, 260) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(Cn2cc(CO)nn2)cc1 Show InChI InChI=1S/C25H21N7O3S/c26-22(34)21-24(36-25(28-21)27-19-10-9-16-3-1-2-4-18(16)11-19)29-23(35)17-7-5-15(6-8-17)12-32-13-20(14-33)30-31-32/h1-11,13,33H,12,14H2,(H2,26,34)(H,27,28)(H,29,35)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.30	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM173988 (US9102637, 23) Show SMILES NCc1ccc(cc1)C(=O)Nc1sc(Nc2ccc3ccccc3c2)nc1C(N)=O Show InChI InChI=1S/C22H19N5O2S/c23-12-13-5-7-15(8-6-13)20(29)27-21-18(19(24)28)26-22(30-21)25-17-10-9-14-3-1-2-4-16(14)11-17/h1-11H,12,23H2,(H2,24,28)(H,25,26)(H,27,29)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.30	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174167 (US9102637, 202) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(CN2CC[C@@H](O)C2)cc1 |r| Show InChI InChI=1S/C26H25N5O3S/c27-23(33)22-25(35-26(29-22)28-20-10-9-17-3-1-2-4-19(17)13-20)30-24(34)18-7-5-16(6-8-18)14-31-12-11-21(32)15-31/h1-10,13,21,32H,11-12,14-15H2,(H2,27,33)(H,28,29)(H,30,34)/t21-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174035 (US9102637, 70) Show SMILES NC(=O)c1nc(Nc2ccc3cc(CO)ccc3c2)sc1NC(=O)c1ccsc1 Show InChI InChI=1S/C20H16N4O3S2/c21-17(26)16-19(24-18(27)14-5-6-28-10-14)29-20(23-16)22-15-4-3-12-7-11(9-25)1-2-13(12)8-15/h1-8,10,25H,9H2,(H2,21,26)(H,22,23)(H,24,27)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174224 (US9102637, 259) Show SMILES NC(=O)c1nc(Nc2cccc3cccnc23)sc1NC(=O)c1ccc(Cn2ccnc2)cc1 Show InChI InChI=1S/C24H19N7O2S/c25-21(32)20-23(30-22(33)17-8-6-15(7-9-17)13-31-12-11-26-14-31)34-24(29-20)28-18-5-1-3-16-4-2-10-27-19(16)18/h1-12,14H,13H2,(H2,25,32)(H,28,29)(H,30,33)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174166 (US9102637, 201) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(CN2CC(O)C2)cc1 Show InChI InChI=1S/C25H23N5O3S/c26-22(32)21-24(29-23(33)17-7-5-15(6-8-17)12-30-13-20(31)14-30)34-25(28-21)27-19-10-9-16-3-1-2-4-18(16)11-19/h1-11,20,31H,12-14H2,(H2,26,32)(H,27,28)(H,29,33)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.60	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174016 (US9102637, 51) Show SMILES CN(c1nc(C(N)=O)c(NC(=O)c2csc(CN3CCOCC3)c2)s1)c1ccc2ncccc2c1 Show InChI InChI=1S/C24H24N6O3S2/c1-29(17-4-5-19-15(11-17)3-2-6-26-19)24-27-20(21(25)31)23(35-24)28-22(32)16-12-18(34-14-16)13-30-7-9-33-10-8-30/h2-6,11-12,14H,7-10,13H2,1H3,(H2,25,31)(H,28,32)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.70	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174081 (US9102637, 116) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(CCO)cc1 Show InChI InChI=1S/C23H20N4O3S/c24-20(29)19-22(27-21(30)16-7-5-14(6-8-16)11-12-28)31-23(26-19)25-18-10-9-15-3-1-2-4-17(15)13-18/h1-10,13,28H,11-12H2,(H2,24,29)(H,25,26)(H,27,30)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.80	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174103 (US9102637, 138) Show SMILES NC(=O)c1nc(Nc2ccc3cc(CO)ccc3c2)sc1NC(=O)C1CC1 Show InChI InChI=1S/C19H18N4O3S/c20-16(25)15-18(23-17(26)11-3-4-11)27-19(22-15)21-14-6-5-12-7-10(9-24)1-2-13(12)8-14/h1-2,5-8,11,24H,3-4,9H2,(H2,20,25)(H,21,22)(H,23,26)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.80	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174170 (US9102637, 205) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(Cn2cnnn2)cc1 Show InChI InChI=1S/C23H18N8O2S/c24-20(32)19-22(28-21(33)16-7-5-14(6-8-16)12-31-13-25-29-30-31)34-23(27-19)26-18-10-9-15-3-1-2-4-17(15)11-18/h1-11,13H,12H2,(H2,24,32)(H,26,27)(H,28,33)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.90	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174204 (US9102637, 239) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(Cn2cnc(c2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C25H19N7O4S/c26-22(33)21-24(37-25(29-21)28-19-10-9-16-3-1-2-4-18(16)11-19)30-23(34)17-7-5-15(6-8-17)12-31-13-20(27-14-31)32(35)36/h1-11,13-14H,12H2,(H2,26,33)(H,28,29)(H,30,34)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.90	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174169 (US9102637, 204) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)C#C Show InChI InChI=1S/C17H12N4O2S/c1-2-13(22)20-16-14(15(18)23)21-17(24-16)19-12-8-7-10-5-3-4-6-11(10)9-12/h1,3-9H,(H2,18,23)(H,19,21)(H,20,22)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174213 (US9102637, 248) Show SMILES COc1ccc2cc(Nc3nc(C(N)=O)c(NC(=O)c4ccc(Cn5ccnc5)cc4)s3)ccc2c1 Show InChI InChI=1S/C26H22N6O3S/c1-35-21-9-7-18-12-20(8-6-19(18)13-21)29-26-30-22(23(27)33)25(36-26)31-24(34)17-4-2-16(3-5-17)14-32-11-10-28-15-32/h2-13,15H,14H2,1H3,(H2,27,33)(H,29,30)(H,31,34)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.10	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174222 (US9102637, 257) Show SMILES Cc1nnc(Cc2ccc(cc2)C(=O)Nc2sc(Nc3ccc4ccccc4c3)nc2C(N)=O)o1 Show InChI InChI=1S/C25H20N6O3S/c1-14-30-31-20(34-14)12-15-6-8-17(9-7-15)23(33)29-24-21(22(26)32)28-25(35-24)27-19-11-10-16-4-2-3-5-18(16)13-19/h2-11,13H,12H2,1H3,(H2,26,32)(H,27,28)(H,29,33)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.20	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174154 (US9102637, 189) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(CN2CCCCC2CO)cc1 Show InChI InChI=1S/C28H29N5O3S/c29-25(35)24-27(37-28(31-24)30-22-13-12-19-5-1-2-6-21(19)15-22)32-26(36)20-10-8-18(9-11-20)16-33-14-4-3-7-23(33)17-34/h1-2,5-6,8-13,15,23,34H,3-4,7,14,16-17H2,(H2,29,35)(H,30,31)(H,32,36)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.80	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174209 (US9102637, 244) Show SMILES Cc1nnnn1Cc1ccc(cc1)C(=O)Nc1sc(Nc2ccc3ccccc3c2)nc1C(N)=O Show InChI InChI=1S/C24H20N8O2S/c1-14-29-30-31-32(14)13-15-6-8-17(9-7-15)22(34)28-23-20(21(25)33)27-24(35-23)26-19-11-10-16-4-2-3-5-18(16)12-19/h2-12H,13H2,1H3,(H2,25,33)(H,26,27)(H,28,34)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.10	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174152 (US9102637, 187) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(cc1)N1CCN(CCO)CC1 Show InChI InChI=1S/C27H28N6O3S/c28-24(35)23-26(37-27(30-23)29-21-8-5-18-3-1-2-4-20(18)17-21)31-25(36)19-6-9-22(10-7-19)33-13-11-32(12-14-33)15-16-34/h1-10,17,34H,11-16H2,(H2,28,35)(H,29,30)(H,31,36)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.20	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174093 (US9102637, 128) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6](=O)-[#7]-c1sc(-[#7]-c2ccc3ccc(F)cc3c2)nc1-[#6](-[#7])=O Show InChI InChI=1S/C19H17FN4O2S/c1-10(2)7-15(25)23-18-16(17(21)26)24-19(27-18)22-14-6-4-11-3-5-13(20)8-12(11)9-14/h3-9H,1-2H3,(H2,21,26)(H,22,24)(H,23,25)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.20	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM173998 (US9102637, 33) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc[nH]1 Show InChI InChI=1S/C19H15N5O2S/c20-16(25)15-18(24-17(26)14-6-3-9-21-14)27-19(23-15)22-13-8-7-11-4-1-2-5-12(11)10-13/h1-10,21H,(H2,20,25)(H,22,23)(H,24,26)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.5	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174216 (US9102637, 251) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(Cn2ccnc2)s1 Show InChI InChI=1S/C23H18N6O2S2/c24-20(30)19-22(28-21(31)18-8-7-17(32-18)12-29-10-9-25-13-29)33-23(27-19)26-16-6-5-14-3-1-2-4-15(14)11-16/h1-11,13H,12H2,(H2,24,30)(H,26,27)(H,28,31)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.70	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM173978 (US9102637, 13) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(NCCN2CCCCC2)cc1 Show InChI InChI=1S/C28H30N6O2S/c29-25(35)24-27(37-28(32-24)31-23-13-8-19-6-2-3-7-21(19)18-23)33-26(36)20-9-11-22(12-10-20)30-14-17-34-15-4-1-5-16-34/h2-3,6-13,18,30H,1,4-5,14-17H2,(H2,29,35)(H,31,32)(H,33,36)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174021 (US9102637, 56) Show SMILES CN1CCN(Cc2cc(cs2)C(=O)Nc2sc(Nc3cccc4ncccc34)nc2C(N)=O)CC1 Show InChI InChI=1S/C24H25N7O2S2/c1-30-8-10-31(11-9-30)13-16-12-15(14-34-16)22(33)29-23-20(21(25)32)28-24(35-23)27-19-6-2-5-18-17(19)4-3-7-26-18/h2-7,12,14H,8-11,13H2,1H3,(H2,25,32)(H,27,28)(H,29,33)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.20	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174227 (US9102637, 262) Show SMILES NC(=O)c1nc(Nc2ccc3ccc(F)cc3c2)sc1NC(=O)c1ccc(Cn2ccnc2)cc1 Show InChI InChI=1S/C25H19FN6O2S/c26-19-7-5-16-6-8-20(12-18(16)11-19)29-25-30-21(22(27)33)24(35-25)31-23(34)17-3-1-15(2-4-17)13-32-10-9-28-14-32/h1-12,14H,13H2,(H2,27,33)(H,29,30)(H,31,34)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.40	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174153 (US9102637, 188) Show SMILES NCCNc1ccc(cc1)C(=O)Nc1sc(Nc2ccc3ccccc3c2)nc1C(N)=O Show InChI InChI=1S/C23H22N6O2S/c24-11-12-26-17-8-6-15(7-9-17)21(31)29-22-19(20(25)30)28-23(32-22)27-18-10-5-14-3-1-2-4-16(14)13-18/h1-10,13,26H,11-12,24H2,(H2,25,30)(H,27,28)(H,29,31)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.40	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM173976 (US9102637, 11) Show SMILES CN(C)CCNc1ccc(cc1)C(=O)Nc1sc(Nc2ccc3ccccc3c2)nc1C(N)=O Show InChI InChI=1S/C25H26N6O2S/c1-31(2)14-13-27-19-10-8-17(9-11-19)23(33)30-24-21(22(26)32)29-25(34-24)28-20-12-7-16-5-3-4-6-18(16)15-20/h3-12,15,27H,13-14H2,1-2H3,(H2,26,32)(H,28,29)(H,30,33)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.60	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM173983 (US9102637, 18) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1ccc(CN2CCOCC2)cc1 Show InChI InChI=1S/C26H25N5O3S/c27-23(32)22-25(35-26(29-22)28-21-10-9-18-3-1-2-4-20(18)15-21)30-24(33)19-7-5-17(6-8-19)16-31-11-13-34-14-12-31/h1-10,15H,11-14,16H2,(H2,27,32)(H,28,29)(H,30,33)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.60	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM174223 (US9102637, 258) Show SMILES NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)c1csc(Cn2ccnc2)c1 Show InChI InChI=1S/C23H18N6O2S2/c24-20(30)19-22(28-21(31)16-10-18(32-12-16)11-29-8-7-25-13-29)33-23(27-19)26-17-6-5-14-3-1-2-4-15(14)9-17/h1-10,12-13H,11H2,(H2,24,30)(H,26,27)(H,28,31)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.70	n/a	n/a	n/a	n/a	7.5	25
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER US Patent					Assay Description The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...				US Patent US9102637 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q9T
					More data for this Ligand-Target Pair

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