Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank MMDB PDB Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | 7.4 | 25 |
GITAM University | Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes as repo... | J Enzyme Inhib Med Chem 27: 97-100 (2012) Article DOI: 10.3109/14756366.2011.578393 BindingDB Entry DOI: 10.7270/Q2HH6HZG | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | 350 | n/a | n/a | n/a | n/a | 7.4 | 25 |
GITAM University | Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes as repo... | J Enzyme Inhib Med Chem 27: 97-100 (2012) Article DOI: 10.3109/14756366.2011.578393 BindingDB Entry DOI: 10.7270/Q2HH6HZG | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM10849 (1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-d...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.00E+6 | n/a | n/a | n/a | n/a | 7.4 | 25 |
GITAM University | Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes as repo... | J Enzyme Inhib Med Chem 27: 97-100 (2012) Article DOI: 10.3109/14756366.2011.578393 BindingDB Entry DOI: 10.7270/Q2HH6HZG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50148573 ((E,E)-1-piperoylpiperidine | 1-[(2E,4E)-5-(1,3-ben...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.00E+6 | n/a | n/a | n/a | n/a | 7.4 | 25 |
GITAM University | Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes as repo... | J Enzyme Inhib Med Chem 27: 97-100 (2012) Article DOI: 10.3109/14756366.2011.578393 BindingDB Entry DOI: 10.7270/Q2HH6HZG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM10849 (1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-d...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 5.50E+7 | n/a | n/a | n/a | n/a | 7.4 | 25 |
GITAM University | Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes as repo... | J Enzyme Inhib Med Chem 27: 97-100 (2012) Article DOI: 10.3109/14756366.2011.578393 BindingDB Entry DOI: 10.7270/Q2HH6HZG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50148573 ((E,E)-1-piperoylpiperidine | 1-[(2E,4E)-5-(1,3-ben...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 6.00E+7 | n/a | n/a | n/a | n/a | 7.4 | 25 |
GITAM University | Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes as repo... | J Enzyme Inhib Med Chem 27: 97-100 (2012) Article DOI: 10.3109/14756366.2011.578393 BindingDB Entry DOI: 10.7270/Q2HH6HZG | |||||||||||
More data for this Ligand-Target Pair |