Compile Data Set for Download or QSAR

Found 26 hits Enz. Inhib. hit(s) with all data for entry = 50001696   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50000788 ((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...) Show SMILES Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O |r| Show InChI InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BOC Technical Center Curated by ChEMBL					Assay Description Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.				J Med Chem 32: 663-71 (1989) BindingDB Entry DOI: 10.7270/Q2N58KC7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50017412 (CHEMBL345120 | Furan-2-carboxylic acid (1-phenethy...) Show SMILES O=C(N(C1CCN(CCc2ccccc2)CC1)c1ccccn1)c1ccco1 Show InChI InChI=1S/C23H25N3O2/c27-23(21-9-6-18-28-21)26(22-10-4-5-14-24-22)20-12-16-25(17-13-20)15-11-19-7-2-1-3-8-19/h1-10,14,18,20H,11-13,15-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BOC Technical Center Curated by ChEMBL					Assay Description Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.				J Med Chem 32: 663-71 (1989) BindingDB Entry DOI: 10.7270/Q2N58KC7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50008984 (4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...) Show SMILES CCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 Show InChI InChI=1S/C22H28N2O/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19/h3-12,21H,2,13-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BOC Technical Center Curated by ChEMBL					Assay Description Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.				J Med Chem 32: 663-71 (1989) BindingDB Entry DOI: 10.7270/Q2N58KC7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50017406 (CHEMBL162700 | Furan-3-carboxylic acid benzo[1,2,5...) Show SMILES O=C(N(C1CCN(CCc2ccccc2)CC1)c1cccc2nsnc12)c1ccoc1 Show InChI InChI=1S/C24H24N4O2S/c29-24(19-12-16-30-17-19)28(22-8-4-7-21-23(22)26-31-25-21)20-10-14-27(15-11-20)13-9-18-5-2-1-3-6-18/h1-8,12,16-17,20H,9-11,13-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BOC Technical Center Curated by ChEMBL					Assay Description Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.				J Med Chem 32: 663-71 (1989) BindingDB Entry DOI: 10.7270/Q2N58KC7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50017416 (CHEMBL347188 | Furan-2-carboxylic acid (4-methyl-p...) Show SMILES Cc1ccnc(c1)N(C1CCN(CCc2ccccc2)CC1)C(=O)c1ccco1 Show InChI InChI=1S/C24H27N3O2/c1-19-9-13-25-23(18-19)27(24(28)22-8-5-17-29-22)21-11-15-26(16-12-21)14-10-20-6-3-2-4-7-20/h2-9,13,17-18,21H,10-12,14-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BOC Technical Center Curated by ChEMBL					Assay Description Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.				J Med Chem 32: 663-71 (1989) BindingDB Entry DOI: 10.7270/Q2N58KC7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50017404 (CHEMBL161084 | Furan-2-carboxylic acid (1-phenethy...) Show SMILES O=C(N(C1CCN(CCc2ccccc2)CC1)c1cnccn1)c1ccco1 Show InChI InChI=1S/C22H24N4O2/c27-22(20-7-4-16-28-20)26(21-17-23-11-12-24-21)19-9-14-25(15-10-19)13-8-18-5-2-1-3-6-18/h1-7,11-12,16-17,19H,8-10,13-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid UniChem Patents	PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BOC Technical Center Curated by ChEMBL					Assay Description Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.				J Med Chem 32: 663-71 (1989) BindingDB Entry DOI: 10.7270/Q2N58KC7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50017420 (CHEMBL157922 | Furan-2-carboxylic acid (1-phenethy...) Show SMILES O=C(N(C1CCN(CCc2ccccc2)CC1)N1CCCCC1)c1ccco1 Show InChI InChI=1S/C23H31N3O2/c27-23(22-10-7-19-28-22)26(25-14-5-2-6-15-25)21-12-17-24(18-13-21)16-11-20-8-3-1-4-9-20/h1,3-4,7-10,19,21H,2,5-6,11-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BOC Technical Center Curated by ChEMBL					Assay Description Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.				J Med Chem 32: 663-71 (1989) BindingDB Entry DOI: 10.7270/Q2N58KC7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50017403 (CHEMBL161442 | Furan-2-carboxylic acid (1-phenethy...) Show SMILES O=C(N(C1CCN(CCc2ccccc2)CC1)c1cccnc1)c1ccco1 Show InChI InChI=1S/C23H25N3O2/c27-23(22-9-5-17-28-22)26(21-8-4-13-24-18-21)20-11-15-25(16-12-20)14-10-19-6-2-1-3-7-19/h1-9,13,17-18,20H,10-12,14-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	8.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BOC Technical Center Curated by ChEMBL					Assay Description The ability of the compound to displace [3H]-naloxone from the opioid receptor mu isolated from rat brain membrane.				J Med Chem 32: 663-71 (1989) BindingDB Entry DOI: 10.7270/Q2N58KC7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50017405 (2-Methoxy-N-(1-phenethyl-piperidin-4-yl)-N-pyridin...) Show SMILES COCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccn1 Show InChI InChI=1S/C21H27N3O2/c1-26-17-21(25)24(20-9-5-6-13-22-20)19-11-15-23(16-12-19)14-10-18-7-3-2-4-8-18/h2-9,13,19H,10-12,14-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BOC Technical Center Curated by ChEMBL					Assay Description The ability of the compound to displace [3H]-naloxone from the Opioid receptor mu isolated from rat brain membrane.				J Med Chem 32: 663-71 (1989) BindingDB Entry DOI: 10.7270/Q2N58KC7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50017411 (CHEMBL158857 | Furan-2-carboxylic acid (1-phenethy...) Show SMILES O=C(N(C1CCN(CCc2ccccc2)CC1)c1ncccn1)c1ccco1 Show InChI InChI=1S/C22H24N4O2/c27-21(20-8-4-17-28-20)26(22-23-12-5-13-24-22)19-10-15-25(16-11-19)14-9-18-6-2-1-3-7-18/h1-8,12-13,17,19H,9-11,14-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BOC Technical Center Curated by ChEMBL					Assay Description Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.				J Med Chem 32: 663-71 (1989) BindingDB Entry DOI: 10.7270/Q2N58KC7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50017410 (2-Methoxy-N-(1-phenethyl-piperidin-4-yl)-N-pyrimid...) Show SMILES COCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ncccn1 Show InChI InChI=1S/C20H26N4O2/c1-26-16-19(25)24(20-21-11-5-12-22-20)18-9-14-23(15-10-18)13-8-17-6-3-2-4-7-17/h2-7,11-12,18H,8-10,13-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BOC Technical Center Curated by ChEMBL					Assay Description Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.				J Med Chem 32: 663-71 (1989) BindingDB Entry DOI: 10.7270/Q2N58KC7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50017409 (CHEMBL161023 | Furan-2-carboxylic acid (6-chloro-p...) Show SMILES Clc1cc(ncn1)N(C1CCN(CCc2ccccc2)CC1)C(=O)c1ccco1 Show InChI InChI=1S/C22H23ClN4O2/c23-20-15-21(25-16-24-20)27(22(28)19-7-4-14-29-19)18-9-12-26(13-10-18)11-8-17-5-2-1-3-6-17/h1-7,14-16,18H,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BOC Technical Center Curated by ChEMBL					Assay Description Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.				J Med Chem 32: 663-71 (1989) BindingDB Entry DOI: 10.7270/Q2N58KC7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50017414 (CHEMBL161147 | Furan-3-carboxylic acid (2-chloro-p...) Show SMILES Clc1ncccc1N(C1CCN(CCc2ccccc2)CC1)C(=O)c1ccoc1 Show InChI InChI=1S/C23H24ClN3O2/c24-22-21(7-4-12-25-22)27(23(28)19-11-16-29-17-19)20-9-14-26(15-10-20)13-8-18-5-2-1-3-6-18/h1-7,11-12,16-17,20H,8-10,13-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BOC Technical Center Curated by ChEMBL					Assay Description Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.				J Med Chem 32: 663-71 (1989) BindingDB Entry DOI: 10.7270/Q2N58KC7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50017413 (CHEMBL161082 | Furan-2-carboxylic acid (2-chloro-p...) Show SMILES Clc1nccc(n1)N(C1CCN(CCc2ccccc2)CC1)C(=O)c1ccco1 Show InChI InChI=1S/C22H23ClN4O2/c23-22-24-12-8-20(25-22)27(21(28)19-7-4-16-29-19)18-10-14-26(15-11-18)13-9-17-5-2-1-3-6-17/h1-8,12,16,18H,9-11,13-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BOC Technical Center Curated by ChEMBL					Assay Description Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.				J Med Chem 32: 663-71 (1989) BindingDB Entry DOI: 10.7270/Q2N58KC7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50017402 (CHEMBL158856 | Furan-3-carboxylic acid (1-phenethy...) Show SMILES O=C(N(C1CCN(CCc2ccccc2)CC1)c1ncccn1)c1ccoc1 Show InChI InChI=1S/C22H24N4O2/c27-21(19-10-16-28-17-19)26(22-23-11-4-12-24-22)20-8-14-25(15-9-20)13-7-18-5-2-1-3-6-18/h1-6,10-12,16-17,20H,7-9,13-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BOC Technical Center Curated by ChEMBL					Assay Description Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.				J Med Chem 32: 663-71 (1989) BindingDB Entry DOI: 10.7270/Q2N58KC7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50017415 (CHEMBL161487 | Furan-2-carboxylic acid morpholin-4...) Show SMILES O=C(N(C1CCN(CCc2ccccc2)CC1)N1CCOCC1)c1ccco1 Show InChI InChI=1S/C22H29N3O3/c26-22(21-7-4-16-28-21)25(24-14-17-27-18-15-24)20-9-12-23(13-10-20)11-8-19-5-2-1-3-6-19/h1-7,16,20H,8-15,17-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BOC Technical Center Curated by ChEMBL					Assay Description The ability of the compound to displace [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane; >= no displacement				J Med Chem 32: 663-71 (1989) BindingDB Entry DOI: 10.7270/Q2N58KC7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50017408 (CHEMBL351672 | Furan-3-carboxylic acid (1-phenethy...) Show SMILES O=C(NC1CCN(CCc2ccccc2)CC1)c1ccoc1 Show InChI InChI=1S/C18H22N2O2/c21-18(16-9-13-22-14-16)19-17-7-11-20(12-8-17)10-6-15-4-2-1-3-5-15/h1-5,9,13-14,17H,6-8,10-12H2,(H,19,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	>100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BOC Technical Center Curated by ChEMBL					Assay Description The ability of the compound to displace [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane; >= no displacement				J Med Chem 32: 663-71 (1989) BindingDB Entry DOI: 10.7270/Q2N58KC7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50017407 (CHEMBL161057 | Furan-3-carboxylic acid (6-chloro-p...) Show SMILES Clc1cc(ncn1)N(C1CCN(CCc2ccccc2)CC1)C(=O)c1ccoc1 Show InChI InChI=1S/C22H23ClN4O2/c23-20-14-21(25-16-24-20)27(22(28)18-9-13-29-15-18)19-7-11-26(12-8-19)10-6-17-4-2-1-3-5-17/h1-5,9,13-16,19H,6-8,10-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BOC Technical Center Curated by ChEMBL					Assay Description The ability of the compound to displace [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane; >= absolutely no % change				J Med Chem 32: 663-71 (1989) BindingDB Entry DOI: 10.7270/Q2N58KC7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50017401 (CHEMBL422180 | Furan-3-carboxylic acid (1-phenethy...) Show SMILES O=C(N(C1CCN(CCc2ccccc2)CC1)c1ccncc1)c1ccoc1 Show InChI InChI=1S/C23H25N3O2/c27-23(20-11-17-28-18-20)26(21-6-12-24-13-7-21)22-9-15-25(16-10-22)14-8-19-4-2-1-3-5-19/h1-7,11-13,17-18,22H,8-10,14-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	>100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BOC Technical Center Curated by ChEMBL					Assay Description The ability of the compound to displace [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane; >= no displacement				J Med Chem 32: 663-71 (1989) BindingDB Entry DOI: 10.7270/Q2N58KC7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50017400 (CHEMBL352442 | Furan-3-carboxylic acid (2-chloro-p...) Show SMILES Clc1nccc(n1)N(C1CCN(CCc2ccccc2)CC1)C(=O)c1ccoc1 Show InChI InChI=1S/C22H23ClN4O2/c23-22-24-11-6-20(25-22)27(21(28)18-10-15-29-16-18)19-8-13-26(14-9-19)12-7-17-4-2-1-3-5-17/h1-6,10-11,15-16,19H,7-9,12-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BOC Technical Center Curated by ChEMBL					Assay Description The ability of the compound to displace [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane; >= no displacement				J Med Chem 32: 663-71 (1989) BindingDB Entry DOI: 10.7270/Q2N58KC7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50017397 (1-Phenethyl-piperidin-4-ylamine | CHEMBL423430) Show SMILES NC1CCN(CCc2ccccc2)CC1 Show InChI InChI=1S/C13H20N2/c14-13-7-10-15(11-8-13)9-6-12-4-2-1-3-5-12/h1-5,13H,6-11,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	>100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BOC Technical Center Curated by ChEMBL					Assay Description The ability of the compound to displace [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane; >= no displacement				J Med Chem 32: 663-71 (1989) BindingDB Entry DOI: 10.7270/Q2N58KC7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50017398 (2-Methoxy-N-morpholin-4-yl-N-(1-phenethyl-piperidi...) Show SMILES COCC(=O)N(C1CCN(CCc2ccccc2)CC1)N1CCOCC1 Show InChI InChI=1S/C20H31N3O3/c1-25-17-20(24)23(22-13-15-26-16-14-22)19-8-11-21(12-9-19)10-7-18-5-3-2-4-6-18/h2-6,19H,7-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BOC Technical Center Curated by ChEMBL					Assay Description The ability of the compound to displace [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane; >= no displacement				J Med Chem 32: 663-71 (1989) BindingDB Entry DOI: 10.7270/Q2N58KC7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50017418 (CHEMBL161512 | Furan-2-carboxylic acid (1-phenethy...) Show SMILES O=C(NC1CCN(CCc2ccccc2)CC1)c1ccco1 Show InChI InChI=1S/C18H22N2O2/c21-18(17-7-4-14-22-17)19-16-9-12-20(13-10-16)11-8-15-5-2-1-3-6-15/h1-7,14,16H,8-13H2,(H,19,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	>100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BOC Technical Center Curated by ChEMBL					Assay Description The ability of the compound to displace [3H]-naloxone from the opioid receptor mu isolated from rat brain membrane; >= no displacement				J Med Chem 32: 663-71 (1989) BindingDB Entry DOI: 10.7270/Q2N58KC7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50017417 (CHEMBL347810 | Furan-3-carboxylic acid (6-chloro-p...) Show SMILES Clc1ccc(cn1)N(C1CCN(CCc2ccccc2)CC1)C(=O)c1ccoc1 Show InChI InChI=1S/C23H24ClN3O2/c24-22-7-6-21(16-25-22)27(23(28)19-11-15-29-17-19)20-9-13-26(14-10-20)12-8-18-4-2-1-3-5-18/h1-7,11,15-17,20H,8-10,12-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BOC Technical Center Curated by ChEMBL					Assay Description The ability of the compound to displace [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane; >= no displacement				J Med Chem 32: 663-71 (1989) BindingDB Entry DOI: 10.7270/Q2N58KC7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50017419 (2-Methoxy-N-(1-phenethyl-piperidin-4-yl)-N-piperid...) Show SMILES COCC(=O)N(C1CCN(CCc2ccccc2)CC1)N1CCCCC1 Show InChI InChI=1S/C21H33N3O2/c1-26-18-21(25)24(23-13-6-3-7-14-23)20-11-16-22(17-12-20)15-10-19-8-4-2-5-9-19/h2,4-5,8-9,20H,3,6-7,10-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BOC Technical Center Curated by ChEMBL					Assay Description The ability of the compound to displace [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane; >= no displacement				J Med Chem 32: 663-71 (1989) BindingDB Entry DOI: 10.7270/Q2N58KC7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50017399 (CHEMBL161280 | N-(6-Chloro-pyrimidin-4-yl)-2-metho...) Show SMILES COCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1cc(Cl)ncn1 Show InChI InChI=1S/C20H25ClN4O2/c1-27-14-20(26)25(19-13-18(21)22-15-23-19)17-8-11-24(12-9-17)10-7-16-5-3-2-4-6-16/h2-6,13,15,17H,7-12,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	214	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BOC Technical Center Curated by ChEMBL					Assay Description Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.				J Med Chem 32: 663-71 (1989) BindingDB Entry DOI: 10.7270/Q2N58KC7
					More data for this Ligand-Target Pair