BindingDB PrimarySearch

Found 10 hits Enz. Inhib. hit(s) with all data for entry = 50002089
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50020192 (8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phen...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	1.45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Binding affinity of the compound against Dopamine receptor D2 of rat was determined using 2 nM of [3H]-sulpiride in binding assay				J Med Chem 31: 1965-8 (1988) BindingDB Entry DOI: 10.7270/Q2NV9H7W
University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50020192 (8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phen...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D2 of rat was determined using 2 nM of [3H]sulpiride in binding assay				J Med Chem 31: 1965-8 (1988) BindingDB Entry DOI: 10.7270/Q2NV9H7W
University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50020192 (8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phen...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1A receptor of rat was determined using [3H]-8-OH-DPAT in binding assay				J Med Chem 31: 1965-8 (1988) BindingDB Entry DOI: 10.7270/Q2NV9H7W
University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50020192 (8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phen...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Binding affinity of the compound against Dopamine receptor D2 of rat was determined using 2 nM of [3H]-sulpiride in binding assay				J Med Chem 31: 1965-8 (1988) BindingDB Entry DOI: 10.7270/Q2NV9H7W
University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50020192 (8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phen...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	858	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1A receptor of rat was determined using [3H]-8-OH-DPAT in binding assay				J Med Chem 31: 1965-8 (1988) BindingDB Entry DOI: 10.7270/Q2NV9H7W
University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...)	BDBM50020192 (8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phen...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	858	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Binding affinity towards serotonin 5-hydroxytryptamine 2 receptor of rat determined using 0.5 nM of [3H]ketanserin in binding assay				J Med Chem 31: 1965-8 (1988) BindingDB Entry DOI: 10.7270/Q2NV9H7W
University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50020192 (8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phen...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Binding affinity against alpha-1 adrenergic receptor of rat was determined using 0.5 nM of [3H]WB-4101 in binding assay				J Med Chem 31: 1965-8 (1988) BindingDB Entry DOI: 10.7270/Q2NV9H7W
University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50020192 (8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phen...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Binding affinity against alpha-1 adrenergic receptor of rat was determined using 0.5 nM of [3H]WB-4101 in binding assay				J Med Chem 31: 1965-8 (1988) BindingDB Entry DOI: 10.7270/Q2NV9H7W
University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM50020192 (8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phen...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1B receptor in rat was determined using 50 uL of [125I]-ICYP in binding assay				J Med Chem 31: 1965-8 (1988) BindingDB Entry DOI: 10.7270/Q2NV9H7W
University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM50020192 (8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phen...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1B receptor in rat was determined using 50 uL of [125I]-ICYP in binding assay				J Med Chem 31: 1965-8 (1988) BindingDB Entry DOI: 10.7270/Q2NV9H7W
University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair