Compile Data Set for Download or QSAR

Found 169 hits Enz. Inhib. hit(s) with all data for entry = 50006993   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056569 (2-((4-(2-(bis(4-fluorophenyl)methoxy)ethyl)piperaz...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(Cc2cc3ccccc3[nH]2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C28H29F2N3O/c29-24-9-5-21(6-10-24)28(22-7-11-25(30)12-8-22)34-18-17-32-13-15-33(16-14-32)20-26-19-23-3-1-2-4-27(23)31-26/h1-12,19,28,31H,13-18,20H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity at the dopamine transporter using [125I]-RTI-55 in rat caudate membranes.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22199 (1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-[(2E)-3-...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(C\C=C\c2ccccc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C28H30F2N2O/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23/h1-15,28H,16-22H2/b7-4+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity was determined at the dopamine transporter labeled with radioligand [125 I] RTI-55				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056560 (2-[4-(2-Benzhydryloxy-ethyl)-piperazin-1-ylmethyl]...) Show SMILES C(CN1CCN(Cc2cc3ccccc3[nH]2)CC1)OC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H31N3O/c1-3-9-23(10-4-1)28(24-11-5-2-6-12-24)32-20-19-30-15-17-31(18-16-30)22-26-21-25-13-7-8-14-27(25)29-26/h1-14,21,28-29H,15-20,22H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity at the dopamine transporter using [125I]-RTI-55 in rat caudate membranes.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22199 (1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-[(2E)-3-...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(C\C=C\c2ccccc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C28H30F2N2O/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23/h1-15,28H,16-22H2/b7-4+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Reuptake inhibition was determined at the dopamine transporter labeled with radioligand [3H]-dopamine in nonstandard conditions on brain membranes ob...				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22165 (1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(CCCc2ccccc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C28H32F2N2O/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23/h1-3,5-6,8-15,28H,4,7,16-22H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Reuptake inhibition was determined at the dopamine transporter labeled with radioligand [3H]-dopamine in nonstandard conditions on brain membranes ob...				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056556 (1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-((E)...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(C\C=C\c2ccco2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C26H28F2N2O2/c27-23-9-5-21(6-10-23)26(22-7-11-24(28)12-8-22)32-20-18-30-16-14-29(15-17-30)13-1-3-25-4-2-19-31-25/h1-12,19,26H,13-18,20H2/b3-1+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity was determined at the dopamine transporter labeled with radioligand [125 I] RTI-55				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056569 (2-((4-(2-(bis(4-fluorophenyl)methoxy)ethyl)piperaz...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(Cc2cc3ccccc3[nH]2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C28H29F2N3O/c29-24-9-5-21(6-10-24)28(22-7-11-25(30)12-8-22)34-18-17-32-13-15-33(16-14-32)20-26-19-23-3-1-2-4-27(23)31-26/h1-12,19,28,31H,13-18,20H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Reuptake inhibition was determined at the dopamine transporter labeled with radioligand [3H]-dopamine in nonstandard conditions on brain membranes ob...				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22199 (1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-[(2E)-3-...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(C\C=C\c2ccccc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C28H30F2N2O/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23/h1-15,28H,16-22H2/b7-4+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity was determined at the dopamine transporter labeled with radioligand [125 I] RTI-55 in nonstandard conditions				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056560 (2-[4-(2-Benzhydryloxy-ethyl)-piperazin-1-ylmethyl]...) Show SMILES C(CN1CCN(Cc2cc3ccccc3[nH]2)CC1)OC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H31N3O/c1-3-9-23(10-4-1)28(24-11-5-2-6-12-24)32-20-19-30-15-17-31(18-16-30)22-26-21-25-13-7-8-14-27(25)29-26/h1-14,21,28-29H,15-20,22H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity was determined at the dopamine transporter labeled with radioligand [125 I] RTI-55 in nonstandard conditions				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056566 (1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-((E)...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(C\C=C\c2cccs2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C26H28F2N2OS/c27-23-9-5-21(6-10-23)26(22-7-11-24(28)12-8-22)31-19-18-30-16-14-29(15-17-30)13-1-3-25-4-2-20-32-25/h1-12,20,26H,13-19H2/b3-1+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity was determined at the dopamine transporter labeled with radioligand [125 I] RTI-55				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056576 (2-[3-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(CCCc2nc3ccccc3[nH]2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C29H32F2N4O/c30-24-11-7-22(8-12-24)29(23-9-13-25(31)14-10-23)36-21-20-35-18-16-34(17-19-35)15-3-6-28-32-26-4-1-2-5-27(26)33-28/h1-2,4-5,7-14,29H,3,6,15-21H2,(H,32,33)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity at the dopamine transporter using [125I]-RTI-55 in rat caudate membranes.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22165 (1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(CCCc2ccccc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C28H32F2N2O/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23/h1-3,5-6,8-15,28H,4,7,16-22H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity was determined at the dopamine transporter labeled with radioligand [125 I] RTI-55 in nonstandard conditions				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056560 (2-[4-(2-Benzhydryloxy-ethyl)-piperazin-1-ylmethyl]...) Show SMILES C(CN1CCN(Cc2cc3ccccc3[nH]2)CC1)OC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H31N3O/c1-3-9-23(10-4-1)28(24-11-5-2-6-12-24)32-20-19-30-15-17-31(18-16-30)22-26-21-25-13-7-8-14-27(25)29-26/h1-14,21,28-29H,15-20,22H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Reuptake inhibition was determined at the dopamine transporter labeled with radioligand [3H]-dopamine in nonstandard conditions on brain membranes ob...				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056569 (2-((4-(2-(bis(4-fluorophenyl)methoxy)ethyl)piperaz...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(Cc2cc3ccccc3[nH]2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C28H29F2N3O/c29-24-9-5-21(6-10-24)28(22-7-11-25(30)12-8-22)34-18-17-32-13-15-33(16-14-32)20-26-19-23-3-1-2-4-27(23)31-26/h1-12,19,28,31H,13-18,20H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity was determined at the dopamine transporter labeled with radioligand [125 I] RTI-55 in nonstandard conditions				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056567 (1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-(3-t...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(CCCc2cccs2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C26H30F2N2OS/c27-23-9-5-21(6-10-23)26(22-7-11-24(28)12-8-22)31-19-18-30-16-14-29(15-17-30)13-1-3-25-4-2-20-32-25/h2,4-12,20,26H,1,3,13-19H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity was determined at the dopamine transporter labeled with radioligand [125 I] RTI-55				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22167 (1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)pip...) Show SMILES C(CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)Cc1ccccc1 Show InChI InChI=1S/C28H34N2O/c1-4-11-25(12-5-1)13-10-18-29-19-21-30(22-20-29)23-24-31-28(26-14-6-2-7-15-26)27-16-8-3-9-17-27/h1-9,11-12,14-17,28H,10,13,18-24H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Reuptake inhibition at the dopamine transporter labeled with radioligand [3H]-dopamine on synaptosomes obtained from rat caudate.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22165 (1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(CCCc2ccccc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C28H32F2N2O/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23/h1-3,5-6,8-15,28H,4,7,16-22H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity was determined at the dopamine transporter labeled with radioligand [125 I] RTI-55				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22167 (1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)pip...) Show SMILES C(CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)Cc1ccccc1 Show InChI InChI=1S/C28H34N2O/c1-4-11-25(12-5-1)13-10-18-29-19-21-30(22-20-29)23-24-31-28(26-14-6-2-7-15-26)27-16-8-3-9-17-27/h1-9,11-12,14-17,28H,10,13,18-24H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity at the dopamine transporter using [125I]-RTI-55 in rat caudate membranes.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056568 (1-(benzo[b]thiophen-2-ylmethyl)-4-(2-(bis(4-fluoro...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(Cc2cc3ccccc3s2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C28H28F2N2OS/c29-24-9-5-21(6-10-24)28(22-7-11-25(30)12-8-22)33-18-17-31-13-15-32(16-14-31)20-26-19-23-3-1-2-4-27(23)34-26/h1-12,19,28H,13-18,20H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity at the dopamine transporter using [125I]-RTI-55 in rat caudate membranes.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056557 (1-(2-Benzhydryloxy-ethyl)-4-((E)-3-furan-2-yl-ally...) Show SMILES C(CN1CCN(C\C=C\c2ccco2)CC1)OC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H30N2O2/c1-3-9-23(10-4-1)26(24-11-5-2-6-12-24)30-22-20-28-18-16-27(17-19-28)15-7-13-25-14-8-21-29-25/h1-14,21,26H,15-20,22H2/b13-7+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity at the dopamine transporter using [125I]-RTI-55 in rat caudate membranes.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056554 (1-(2-Benzhydryloxy-ethyl)-4-(3-thiophen-2-yl-propy...) Show SMILES C(CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)Cc1cccs1 Show InChI InChI=1S/C26H32N2OS/c1-3-9-23(10-4-1)26(24-11-5-2-6-12-24)29-21-20-28-18-16-27(17-19-28)15-7-13-25-14-8-22-30-25/h1-6,8-12,14,22,26H,7,13,15-21H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity at the dopamine transporter using [125I]-RTI-55 in rat caudate membranes.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056553 (1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-(3-f...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(CCCc2ccco2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C26H30F2N2O2/c27-23-9-5-21(6-10-23)26(22-7-11-24(28)12-8-22)32-20-18-30-16-14-29(15-17-30)13-1-3-25-4-2-19-31-25/h2,4-12,19,26H,1,3,13-18,20H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity was determined at the dopamine transporter labeled with radioligand [125 I] RTI-55				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056567 (1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-(3-t...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(CCCc2cccs2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C26H30F2N2OS/c27-23-9-5-21(6-10-23)26(22-7-11-24(28)12-8-22)31-19-18-30-16-14-29(15-17-30)13-1-3-25-4-2-20-32-25/h2,4-12,20,26H,1,3,13-19H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Reuptake inhibition at the dopamine transporter labeled with radioligand [3H]-dopamine on synaptosomes obtained from rat caudate.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056573 (1-(2-Benzhydryloxy-ethyl)-4-((E)-3-thiophen-2-yl-a...) Show SMILES C(CN1CCN(C\C=C\c2cccs2)CC1)OC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H30N2OS/c1-3-9-23(10-4-1)26(24-11-5-2-6-12-24)29-21-20-28-18-16-27(17-19-28)15-7-13-25-14-8-22-30-25/h1-14,22,26H,15-21H2/b13-7+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity at the dopamine transporter using [125I]-RTI-55 in rat caudate membranes.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056551 (1-(benzofuran-2-ylmethyl)-4-(2-(bis(4-fluorophenyl...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(Cc2cc3ccccc3o2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C28H28F2N2O2/c29-24-9-5-21(6-10-24)28(22-7-11-25(30)12-8-22)33-18-17-31-13-15-32(16-14-31)20-26-19-23-3-1-2-4-27(23)34-26/h1-12,19,28H,13-18,20H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity at the dopamine transporter using [125I]-RTI-55 in rat caudate membranes.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056562 (1-(2-Benzhydryloxy-ethyl)-4-(3-furan-2-yl-propyl)-...) Show SMILES C(CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)Cc1ccco1 Show InChI InChI=1S/C26H32N2O2/c1-3-9-23(10-4-1)26(24-11-5-2-6-12-24)30-22-20-28-18-16-27(17-19-28)15-7-13-25-14-8-21-29-25/h1-6,8-12,14,21,26H,7,13,15-20,22H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity at the dopamine transporter using [125I]-RTI-55 in rat caudate membranes.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056556 (1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-((E)...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(C\C=C\c2ccco2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C26H28F2N2O2/c27-23-9-5-21(6-10-23)26(22-7-11-24(28)12-8-22)32-20-18-30-16-14-29(15-17-30)13-1-3-25-4-2-19-31-25/h1-12,19,26H,13-18,20H2/b3-1+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Reuptake inhibition at the dopamine transporter labeled with radioligand [3H]-dopamine on synaptosomes obtained from rat caudate.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22165 (1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(CCCc2ccccc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C28H32F2N2O/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23/h1-3,5-6,8-15,28H,4,7,16-22H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Reuptake inhibition at the dopamine transporter labeled with radioligand [3H]-dopamine on synaptosomes obtained from rat caudate.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056570 (1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-(2-n...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(CCc2cccc3ccccc23)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C31H32F2N2O/c32-28-12-8-26(9-13-28)31(27-10-14-29(33)15-11-27)36-23-22-35-20-18-34(19-21-35)17-16-25-6-3-5-24-4-1-2-7-30(24)25/h1-15,31H,16-23H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity at the dopamine transporter using [125I]-RTI-55 in rat caudate membranes.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056553 (1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-(3-f...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(CCCc2ccco2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C26H30F2N2O2/c27-23-9-5-21(6-10-23)26(22-7-11-24(28)12-8-22)32-20-18-30-16-14-29(15-17-30)13-1-3-25-4-2-19-31-25/h2,4-12,19,26H,1,3,13-18,20H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Reuptake inhibition at the dopamine transporter labeled with radioligand [3H]-dopamine on synaptosomes obtained from rat caudate.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056571 (1-(2-(bis(4-fluorophenyl)methoxy)ethyl)-4-(naphtha...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(Cc2ccc3ccccc3c2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C30H30F2N2O/c31-28-11-7-25(8-12-28)30(26-9-13-29(32)14-10-26)35-20-19-33-15-17-34(18-16-33)22-23-5-6-24-3-1-2-4-27(24)21-23/h1-14,21,30H,15-20,22H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity at the dopamine transporter using [125I]-RTI-55 in rat caudate membranes.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056576 (2-[3-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(CCCc2nc3ccccc3[nH]2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C29H32F2N4O/c30-24-11-7-22(8-12-24)29(23-9-13-25(31)14-10-23)36-21-20-35-18-16-34(17-19-35)15-3-6-28-32-26-4-1-2-5-27(26)33-28/h1-2,4-5,7-14,29H,3,6,15-21H2,(H,32,33)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Reuptake inhibition at the dopamine transporter labeled with radioligand [3H]-dopamine on synaptosomes obtained from rat caudate.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056562 (1-(2-Benzhydryloxy-ethyl)-4-(3-furan-2-yl-propyl)-...) Show SMILES C(CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)Cc1ccco1 Show InChI InChI=1S/C26H32N2O2/c1-3-9-23(10-4-1)26(24-11-5-2-6-12-24)30-22-20-28-18-16-27(17-19-28)15-7-13-25-14-8-21-29-25/h1-6,8-12,14,21,26H,7,13,15-20,22H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Reuptake inhibition at the dopamine transporter labeled with radioligand [3H]-dopamine on synaptosomes obtained from rat caudate.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056560 (2-[4-(2-Benzhydryloxy-ethyl)-piperazin-1-ylmethyl]...) Show SMILES C(CN1CCN(Cc2cc3ccccc3[nH]2)CC1)OC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H31N3O/c1-3-9-23(10-4-1)28(24-11-5-2-6-12-24)32-20-19-30-15-17-31(18-16-30)22-26-21-25-13-7-8-14-27(25)29-26/h1-14,21,28-29H,15-20,22H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.80	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Reuptake inhibition at the dopamine transporter labeled with radioligand [3H]-dopamine on synaptosomes obtained from rat caudate.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056557 (1-(2-Benzhydryloxy-ethyl)-4-((E)-3-furan-2-yl-ally...) Show SMILES C(CN1CCN(C\C=C\c2ccco2)CC1)OC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H30N2O2/c1-3-9-23(10-4-1)26(24-11-5-2-6-12-24)30-22-20-28-18-16-27(17-19-28)15-7-13-25-14-8-21-29-25/h1-14,21,26H,15-20,22H2/b13-7+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.60	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Reuptake inhibition at the dopamine transporter labeled with radioligand [3H]-dopamine on synaptosomes obtained from rat caudate.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056554 (1-(2-Benzhydryloxy-ethyl)-4-(3-thiophen-2-yl-propy...) Show SMILES C(CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)Cc1cccs1 Show InChI InChI=1S/C26H32N2OS/c1-3-9-23(10-4-1)26(24-11-5-2-6-12-24)29-21-20-28-18-16-27(17-19-28)15-7-13-25-14-8-22-30-25/h1-6,8-12,14,22,26H,7,13,15-21H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Reuptake inhibition at the dopamine transporter labeled with radioligand [3H]-dopamine on synaptosomes obtained from rat caudate.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056573 (1-(2-Benzhydryloxy-ethyl)-4-((E)-3-thiophen-2-yl-a...) Show SMILES C(CN1CCN(C\C=C\c2cccs2)CC1)OC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H30N2OS/c1-3-9-23(10-4-1)26(24-11-5-2-6-12-24)29-21-20-28-18-16-27(17-19-28)15-7-13-25-14-8-22-30-25/h1-14,22,26H,15-21H2/b13-7+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Reuptake inhibition at the dopamine transporter labeled with radioligand [3H]-dopamine on synaptosomes obtained from rat caudate.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22199 (1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-[(2E)-3-...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(C\C=C\c2ccccc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C28H30F2N2O/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23/h1-15,28H,16-22H2/b7-4+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Reuptake inhibition at the dopamine transporter labeled with radioligand [3H]-dopamine on synaptosomes obtained from rat caudate.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056551 (1-(benzofuran-2-ylmethyl)-4-(2-(bis(4-fluorophenyl...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(Cc2cc3ccccc3o2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C28H28F2N2O2/c29-24-9-5-21(6-10-24)28(22-7-11-25(30)12-8-22)33-18-17-31-13-15-32(16-14-31)20-26-19-23-3-1-2-4-27(23)34-26/h1-12,19,28H,13-18,20H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Reuptake inhibition was determined at the dopamine transporter labeled with radioligand [3H]-dopamine in nonstandard conditions on brain membranes ob...				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056566 (1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-((E)...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(C\C=C\c2cccs2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C26H28F2N2OS/c27-23-9-5-21(6-10-23)26(22-7-11-24(28)12-8-22)31-19-18-30-16-14-29(15-17-30)13-1-3-25-4-2-20-32-25/h1-12,20,26H,13-19H2/b3-1+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Reuptake inhibition at the dopamine transporter labeled with radioligand [3H]-dopamine on synaptosomes obtained from rat caudate.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056569 (2-((4-(2-(bis(4-fluorophenyl)methoxy)ethyl)piperaz...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(Cc2cc3ccccc3[nH]2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C28H29F2N3O/c29-24-9-5-21(6-10-24)28(22-7-11-25(30)12-8-22)34-18-17-32-13-15-33(16-14-32)20-26-19-23-3-1-2-4-27(23)31-26/h1-12,19,28,31H,13-18,20H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Reuptake inhibition at the dopamine transporter labeled with radioligand [3H]-dopamine on synaptosomes obtained from rat caudate.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056579 (1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-((E)...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(C\C=C\c2cccnc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C27H29F2N3O/c28-25-9-5-23(6-10-25)27(24-7-11-26(29)12-8-24)33-20-19-32-17-15-31(16-18-32)14-2-4-22-3-1-13-30-21-22/h1-13,21,27H,14-20H2/b4-2+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity was determined at the dopamine transporter labeled with radioligand [125 I] RTI-55				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056565 (2-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-pip...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(Cc2nc3ccccc3[nH]2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C27H28F2N4O/c28-22-9-5-20(6-10-22)27(21-7-11-23(29)12-8-21)34-18-17-32-13-15-33(16-14-32)19-26-30-24-3-1-2-4-25(24)31-26/h1-12,27H,13-19H2,(H,30,31)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity at the dopamine transporter using [125I]-RTI-55 in rat caudate membranes.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056579 (1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-((E)...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(C\C=C\c2cccnc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C27H29F2N3O/c28-25-9-5-23(6-10-25)27(24-7-11-26(29)12-8-24)33-20-19-32-17-15-31(16-18-32)14-2-4-22-3-1-13-30-21-22/h1-13,21,27H,14-20H2/b4-2+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Reuptake inhibition at the dopamine transporter labeled with radioligand [3H]-dopamine on synaptosomes obtained from rat caudate.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056577 (3-((4-(2-(bis(4-fluorophenyl)methoxy)ethyl)piperaz...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(Cc2cnc3ccccc3c2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C29H29F2N3O/c30-26-9-5-23(6-10-26)29(24-7-11-27(31)12-8-24)35-18-17-33-13-15-34(16-14-33)21-22-19-25-3-1-2-4-28(25)32-20-22/h1-12,19-20,29H,13-18,21H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity at the dopamine transporter using [125I]-RTI-55 in rat caudate membranes.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056575 (1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-(3-p...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(CCCc2cccnc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C27H31F2N3O/c28-25-9-5-23(6-10-25)27(24-7-11-26(29)12-8-24)33-20-19-32-17-15-31(16-18-32)14-2-4-22-3-1-13-30-21-22/h1,3,5-13,21,27H,2,4,14-20H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity was determined at the dopamine transporter labeled with radioligand [125 I] RTI-55				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056572 (1-(2-Benzhydryloxy-ethyl)-4-benzofuran-2-ylmethyl-...) Show SMILES C(CN1CCN(Cc2cc3ccccc3o2)CC1)OC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H30N2O2/c1-3-9-23(10-4-1)28(24-11-5-2-6-12-24)31-20-19-29-15-17-30(18-16-29)22-26-21-25-13-7-8-14-27(25)32-26/h1-14,21,28H,15-20,22H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity at the dopamine transporter using [125I]-RTI-55 in rat caudate membranes.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM22167 (1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)pip...) Show SMILES C(CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)Cc1ccccc1 Show InChI InChI=1S/C28H34N2O/c1-4-11-25(12-5-1)13-10-18-29-19-21-30(22-20-29)23-24-31-28(26-14-6-2-7-15-26)27-16-8-3-9-17-27/h1-9,11-12,14-17,28H,10,13,18-24H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Sigma receptor binding was determined by labeling with radioligand [3H]-(+)-pentazocine on frozen membranes obtained from frozen guinea pig brain				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056550 (2-{3-[4-(2-Benzhydryloxy-ethyl)-piperazin-1-yl]-pr...) Show SMILES C(CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)Cc1nc2ccccc2[nH]1 Show InChI InChI=1S/C29H34N4O/c1-3-10-24(11-4-1)29(25-12-5-2-6-13-25)34-23-22-33-20-18-32(19-21-33)17-9-16-28-30-26-14-7-8-15-27(26)31-28/h1-8,10-15,29H,9,16-23H2,(H,30,31)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Reuptake inhibition at the dopamine transporter labeled with radioligand [3H]-dopamine on synaptosomes obtained from rat caudate.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056561 (1-(2-Benzhydryloxy-ethyl)-4-benzo[b]thiophen-2-ylm...) Show SMILES C(CN1CCN(Cc2cc3ccccc3s2)CC1)OC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H30N2OS/c1-3-9-23(10-4-1)28(24-11-5-2-6-12-24)31-20-19-29-15-17-30(18-16-29)22-26-21-25-13-7-8-14-27(25)32-26/h1-14,21,28H,15-20,22H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity at the dopamine transporter using [125I]-RTI-55 in rat caudate membranes.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair

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