Found 171 hits Enz. Inhib. hit(s) with all data for entry = 50020217 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Melanocortin receptor 5
(Homo sapiens (Human)) | BDBM50211392
(Ac-Nle4-cyclo(Asp5-Pro6-D-4,4'-Bip7-Pro8-Trp9-Lys1...)Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC(=O)[C@]1([H])CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C54H68N10O9/c1-3-4-17-41(58-33(2)65)49(68)61-44-31-47(66)56-26-11-10-19-40(48(55)67)59-50(69)42(30-37-32-57-39-18-9-8-16-38(37)39)60-51(70)45-20-12-27-63(45)53(72)43(62-52(71)46-21-13-28-64(46)54(44)73)29-34-22-24-36(25-23-34)35-14-6-5-7-15-35/h5-9,14-16,18,22-25,32,40-46,57H,3-4,10-13,17,19-21,26-31H2,1-2H3,(H2,55,67)(H,56,66)(H,58,65)(H,59,69)(H,60,70)(H,61,68)(H,62,71)/t40?,41-,42-,43-,44-,45-,46-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50211392
(Ac-Nle4-cyclo(Asp5-Pro6-D-4,4'-Bip7-Pro8-Trp9-Lys1...)Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC(=O)[C@]1([H])CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C54H68N10O9/c1-3-4-17-41(58-33(2)65)49(68)61-44-31-47(66)56-26-11-10-19-40(48(55)67)59-50(69)42(30-37-32-57-39-18-9-8-16-38(37)39)60-51(70)45-20-12-27-63(45)53(72)43(62-52(71)46-21-13-28-64(46)54(44)73)29-34-22-24-36(25-23-34)35-14-6-5-7-15-35/h5-9,14-16,18,22-25,32,40-46,57H,3-4,10-13,17,19-21,26-31H2,1-2H3,(H2,55,67)(H,56,66)(H,58,65)(H,59,69)(H,60,70)(H,61,68)(H,62,71)/t40?,41-,42-,43-,44-,45-,46-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
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| CHEMBL
PC cid
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| Article
PubMed
| n/a | n/a | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Homo sapiens (Human)) | BDBM50211392
(Ac-Nle4-cyclo(Asp5-Pro6-D-4,4'-Bip7-Pro8-Trp9-Lys1...)Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC(=O)[C@]1([H])CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C54H68N10O9/c1-3-4-17-41(58-33(2)65)49(68)61-44-31-47(66)56-26-11-10-19-40(48(55)67)59-50(69)42(30-37-32-57-39-18-9-8-16-38(37)39)60-51(70)45-20-12-27-63(45)53(72)43(62-52(71)46-21-13-28-64(46)54(44)73)29-34-22-24-36(25-23-34)35-14-6-5-7-15-35/h5-9,14-16,18,22-25,32,40-46,57H,3-4,10-13,17,19-21,26-31H2,1-2H3,(H2,55,67)(H,56,66)(H,58,65)(H,59,69)(H,60,70)(H,61,68)(H,62,71)/t40?,41-,42-,43-,44-,45-,46-/m0/s1 | PDB
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| n/a | n/a | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC4R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Homo sapiens (Human)) | BDBM50211397
(Ac-Nle4-cyclo(Asp5-Oic6-D-4,4'-Bip7-Pro8-Trp9-Lys1...)Show SMILES [H][C@@]12CC3CCCCC3N1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC(=O)[C@]1([H])CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C58H74N10O9/c1-3-4-19-44(62-35(2)69)53(72)65-47-33-51(70)60-28-13-12-21-43(52(59)71)63-54(73)45(31-40-34-61-42-20-10-9-18-41(40)42)64-55(74)49-23-14-29-67(49)57(76)46(30-36-24-26-38(27-25-36)37-15-6-5-7-16-37)66-56(75)50-32-39-17-8-11-22-48(39)68(50)58(47)77/h5-7,9-10,15-16,18,20,24-27,34,39,43-50,61H,3-4,8,11-14,17,19,21-23,28-33H2,1-2H3,(H2,59,71)(H,60,70)(H,62,69)(H,63,73)(H,64,74)(H,65,72)(H,66,75)/t39?,43?,44-,45-,46-,47-,48?,49-,50-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
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| CHEMBL
PC cid
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| Article
PubMed
| n/a | n/a | 0.950 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Homo sapiens (Human)) | BDBM50211374
(CHEMBL2371967 | c-Nle4-cyclo(Asp5-Tic6-D-4,4'-Bip7...)Show SMILES [H][C@@]12CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@]1([H])Cc3ccccc3CN1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C60H72N10O9/c1-3-4-21-47(64-37(2)71)55(74)67-50-34-53(72)62-29-14-12-23-46(54(61)73)65-56(75)48(32-43-35-63-45-22-11-10-20-44(43)45)66-57(76)51-24-13-15-30-69(51)59(78)49(31-38-25-27-40(28-26-38)39-16-6-5-7-17-39)68-58(77)52-33-41-18-8-9-19-42(41)36-70(52)60(50)79/h5-11,16-20,22,25-28,35,46-52,63H,3-4,12-15,21,23-24,29-34,36H2,1-2H3,(H2,61,73)(H,62,72)(H,64,71)(H,65,75)(H,66,76)(H,67,74)(H,68,77)/t46?,47-,48-,49-,50-,51-,52-/m0/s1 | PDB
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| CHEMBL
PC cid
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| n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Homo sapiens (Human)) | BDBM50211377
(Ac-Nle4-cyclo(Asp5-His6-D-4,4'-Bip-Pro8-Trp9-Lys10...)Show SMILES CCCC[C@H](NC(C)=O)C(=O)C[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccc(cc2)-c2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C56H69N11O9/c1-3-4-16-43(61-34(2)68)49(69)28-39-29-50(70)59-24-11-10-18-44(51(57)71)63-53(73)45(30-40-27-38-15-8-9-17-42(38)62-40)65-55(75)48-19-12-25-67(48)56(76)47(26-35-20-22-37(23-21-35)36-13-6-5-7-14-36)66-54(74)46(64-52(39)72)31-41-32-58-33-60-41/h5-9,13-15,17,20-23,27,32-33,39,43-48,62H,3-4,10-12,16,18-19,24-26,28-31H2,1-2H3,(H2,57,71)(H,58,60)(H,59,70)(H,61,68)(H,63,73)(H,64,72)(H,65,75)(H,66,74)/t39-,43-,44-,45-,46-,47+,48-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Homo sapiens (Human)) | BDBM50211375
(Ac-Nle4-cyclo(Asp5-His6-D-4,4'-Bip7-Pip8-Trp9-Lys1...)Show SMILES [H][C@@]12CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C56H70N12O9/c1-3-4-17-43(62-34(2)69)51(72)65-46-30-49(70)59-25-12-10-19-42(50(57)71)63-52(73)44(28-38-31-60-41-18-9-8-16-40(38)41)66-55(76)48-20-11-13-26-68(48)56(77)47(27-35-21-23-37(24-22-35)36-14-6-5-7-15-36)67-53(74)45(64-54(46)75)29-39-32-58-33-61-39/h5-9,14-16,18,21-24,31-33,42-48,60H,3-4,10-13,17,19-20,25-30H2,1-2H3,(H2,57,71)(H,58,61)(H,59,70)(H,62,69)(H,63,73)(H,64,75)(H,65,72)(H,66,76)(H,67,74)/t42?,43-,44-,45-,46-,47-,48-/m0/s1 | PDB
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| CHEMBL
PC cid
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| Article
PubMed
| n/a | n/a | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC4R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Homo sapiens (Human)) | BDBM50211375
(Ac-Nle4-cyclo(Asp5-His6-D-4,4'-Bip7-Pip8-Trp9-Lys1...)Show SMILES [H][C@@]12CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C56H70N12O9/c1-3-4-17-43(62-34(2)69)51(72)65-46-30-49(70)59-25-12-10-19-42(50(57)71)63-52(73)44(28-38-31-60-41-18-9-8-16-40(38)41)66-55(76)48-20-11-13-26-68(48)56(77)47(27-35-21-23-37(24-22-35)36-14-6-5-7-15-36)67-53(74)45(64-54(46)75)29-39-32-58-33-61-39/h5-9,14-16,18,21-24,31-33,42-48,60H,3-4,10-13,17,19-20,25-30H2,1-2H3,(H2,57,71)(H,58,61)(H,59,70)(H,62,69)(H,63,73)(H,64,75)(H,65,72)(H,66,76)(H,67,74)/t42?,43-,44-,45-,46-,47-,48-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50211375
(Ac-Nle4-cyclo(Asp5-His6-D-4,4'-Bip7-Pip8-Trp9-Lys1...)Show SMILES [H][C@@]12CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C56H70N12O9/c1-3-4-17-43(62-34(2)69)51(72)65-46-30-49(70)59-25-12-10-19-42(50(57)71)63-52(73)44(28-38-31-60-41-18-9-8-16-40(38)41)66-55(76)48-20-11-13-26-68(48)56(77)47(27-35-21-23-37(24-22-35)36-14-6-5-7-15-36)67-53(74)45(64-54(46)75)29-39-32-58-33-61-39/h5-9,14-16,18,21-24,31-33,42-48,60H,3-4,10-13,17,19-20,25-30H2,1-2H3,(H2,57,71)(H,58,61)(H,59,70)(H,62,69)(H,63,73)(H,64,75)(H,65,72)(H,66,76)(H,67,74)/t42?,43-,44-,45-,46-,47-,48-/m0/s1 | PDB
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| CHEMBL
PC cid
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| Article
PubMed
| n/a | n/a | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Homo sapiens (Human)) | BDBM50211369
(Ac-Nle4-cyclo(Asp5-Val6-D-4,4'-Bip7-Pip8-Trp9-Lys1...)Show SMILES [H][C@@]12CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O)C(C)C Show InChI InChI=1S/C55H72N10O9/c1-5-6-19-42(59-34(4)66)50(69)61-44-31-47(67)57-27-14-12-21-41(49(56)68)60-51(70)43(30-38-32-58-40-20-11-10-18-39(38)40)62-53(72)46-22-13-15-28-65(46)55(74)45(63-54(73)48(33(2)3)64-52(44)71)29-35-23-25-37(26-24-35)36-16-8-7-9-17-36/h7-11,16-18,20,23-26,32-33,41-46,48,58H,5-6,12-15,19,21-22,27-31H2,1-4H3,(H2,56,68)(H,57,67)(H,59,66)(H,60,70)(H,61,69)(H,62,72)(H,63,73)(H,64,71)/t41?,42-,43-,44-,45-,46-,48-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Homo sapiens (Human)) | BDBM50211370
(Ac-Nle4-cyclo(Asp5-Oic6-D-D-pBzlPhe7-Pip8-Trp9-Lys...)Show SMILES [H][C@@]12CC3CCCCC3N1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC(=O)[C@]1([H])CCCCN1C(=O)[C@H](Cc1ccc(Cc3ccccc3)cc1)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C60H78N10O9/c1-3-4-20-46(64-37(2)71)55(74)67-49-35-53(72)62-29-14-12-22-45(54(61)73)65-56(75)47(33-42-36-63-44-21-10-9-19-43(42)44)66-57(76)51-24-13-15-30-69(51)59(78)48(32-40-27-25-39(26-28-40)31-38-16-6-5-7-17-38)68-58(77)52-34-41-18-8-11-23-50(41)70(52)60(49)79/h5-7,9-10,16-17,19,21,25-28,36,41,45-52,63H,3-4,8,11-15,18,20,22-24,29-35H2,1-2H3,(H2,61,73)(H,62,72)(H,64,71)(H,65,75)(H,66,76)(H,67,74)(H,68,77)/t41?,45?,46-,47-,48-,49-,50?,51-,52-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50211377
(Ac-Nle4-cyclo(Asp5-His6-D-4,4'-Bip-Pro8-Trp9-Lys10...)Show SMILES CCCC[C@H](NC(C)=O)C(=O)C[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccc(cc2)-c2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C56H69N11O9/c1-3-4-16-43(61-34(2)68)49(69)28-39-29-50(70)59-24-11-10-18-44(51(57)71)63-53(73)45(30-40-27-38-15-8-9-17-42(38)62-40)65-55(75)48-19-12-25-67(48)56(76)47(26-35-20-22-37(23-21-35)36-13-6-5-7-14-36)66-54(74)46(64-52(39)72)31-41-32-58-33-60-41/h5-9,13-15,17,20-23,27,32-33,39,43-48,62H,3-4,10-12,16,18-19,24-26,28-31H2,1-2H3,(H2,57,71)(H,58,60)(H,59,70)(H,61,68)(H,63,73)(H,64,72)(H,65,75)(H,66,74)/t39-,43-,44-,45-,46-,47+,48-/m0/s1 | PDB
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Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Homo sapiens (Human)) | BDBM50211379
(Ac-Nle4-cyclo(Asp5-Chg6-D-4,4'-Bip7-Pip8-Trp9-Lys1...)Show SMILES [H][C@@]12CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O)C1CCCCC1 Show InChI InChI=1S/C58H76N10O9/c1-3-4-22-45(62-36(2)69)53(72)64-47-34-50(70)60-30-15-13-24-44(52(59)71)63-54(73)46(33-41-35-61-43-23-12-11-21-42(41)43)65-56(75)49-25-14-16-31-68(49)58(77)48(32-37-26-28-39(29-27-37)38-17-7-5-8-18-38)66-57(76)51(67-55(47)74)40-19-9-6-10-20-40/h5,7-8,11-12,17-18,21,23,26-29,35,40,44-49,51,61H,3-4,6,9-10,13-16,19-20,22,24-25,30-34H2,1-2H3,(H2,59,71)(H,60,70)(H,62,69)(H,63,73)(H,64,72)(H,65,75)(H,66,76)(H,67,74)/t44?,45-,46-,47-,48-,49-,51-/m0/s1 | PDB
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| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Homo sapiens (Human)) | BDBM50211380
(Ac-Nle4-cyclo(Asp5-His6-D-Nal(2)-Pro8-Trp9-Lys10)-...)Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C53H66N12O9/c1-3-4-15-40(58-31(2)66)48(69)62-43-28-46(67)56-21-10-9-17-39(47(54)68)60-49(70)41(26-36-25-35-14-7-8-16-38(35)59-36)63-52(73)45-18-11-22-65(45)53(74)44(24-32-19-20-33-12-5-6-13-34(33)23-32)64-50(71)42(61-51(43)72)27-37-29-55-30-57-37/h5-8,12-14,16,19-20,23,25,29-30,39-45,59H,3-4,9-11,15,17-18,21-22,24,26-28H2,1-2H3,(H2,54,68)(H,55,57)(H,56,67)(H,58,66)(H,60,70)(H,61,72)(H,62,69)(H,63,73)(H,64,71)/t39-,40-,41-,42-,43-,44+,45-/m0/s1 | PDB
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| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Homo sapiens (Human)) | BDBM50211368
(Ac-Nle4-cyclo(Asp5-His6-D-4-Dip-Pro8-Trp9-Lys10)-N...)Show SMILES [H][C@@]12CCCN1C(=O)[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1cc3ccccc3[nH]1)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C55H68N12O9/c1-3-4-21-41(60-33(2)68)50(71)64-44-30-46(69)58-25-14-13-23-40(49(56)70)62-51(72)42(28-37-27-36-20-11-12-22-39(36)61-37)65-54(75)45-24-15-26-67(45)55(76)48(47(34-16-7-5-8-17-34)35-18-9-6-10-19-35)66-53(74)43(63-52(44)73)29-38-31-57-32-59-38/h5-12,16-20,22,27,31-32,40-45,47-48,61H,3-4,13-15,21,23-26,28-30H2,1-2H3,(H2,56,70)(H,57,59)(H,58,69)(H,60,68)(H,62,72)(H,63,73)(H,64,71)(H,65,75)(H,66,74)/t40-,41-,42-,43-,44?,45-,48+/m0/s1 | PDB
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| n/a | n/a | 74 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC4R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Homo sapiens (Human)) | BDBM50211368
(Ac-Nle4-cyclo(Asp5-His6-D-4-Dip-Pro8-Trp9-Lys10)-N...)Show SMILES [H][C@@]12CCCN1C(=O)[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1cc3ccccc3[nH]1)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C55H68N12O9/c1-3-4-21-41(60-33(2)68)50(71)64-44-30-46(69)58-25-14-13-23-40(49(56)70)62-51(72)42(28-37-27-36-20-11-12-22-39(36)61-37)65-54(75)45-24-15-26-67(45)55(76)48(47(34-16-7-5-8-17-34)35-18-9-6-10-19-35)66-53(74)43(63-52(44)73)29-38-31-57-32-59-38/h5-12,16-20,22,27,31-32,40-45,47-48,61H,3-4,13-15,21,23-26,28-30H2,1-2H3,(H2,56,70)(H,57,59)(H,58,69)(H,60,68)(H,62,72)(H,63,73)(H,64,71)(H,65,75)(H,66,74)/t40-,41-,42-,43-,44?,45-,48+/m0/s1 | PDB
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| n/a | n/a | 74 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50211368
(Ac-Nle4-cyclo(Asp5-His6-D-4-Dip-Pro8-Trp9-Lys10)-N...)Show SMILES [H][C@@]12CCCN1C(=O)[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1cc3ccccc3[nH]1)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C55H68N12O9/c1-3-4-21-41(60-33(2)68)50(71)64-44-30-46(69)58-25-14-13-23-40(49(56)70)62-51(72)42(28-37-27-36-20-11-12-22-39(36)61-37)65-54(75)45-24-15-26-67(45)55(76)48(47(34-16-7-5-8-17-34)35-18-9-6-10-19-35)66-53(74)43(63-52(44)73)29-38-31-57-32-59-38/h5-12,16-20,22,27,31-32,40-45,47-48,61H,3-4,13-15,21,23-26,28-30H2,1-2H3,(H2,56,70)(H,57,59)(H,58,69)(H,60,68)(H,62,72)(H,63,73)(H,64,71)(H,65,75)(H,66,74)/t40-,41-,42-,43-,44?,45-,48+/m0/s1 | PDB
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| n/a | n/a | 74 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Homo sapiens (Human)) | BDBM50211391
(Ac-Nle4-cyclo(Asp5-His6-D-Phe-Pro8-Trp9-Lys10)-NH2...)Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C49H64N12O9/c1-3-4-16-36(54-29(2)62)44(65)58-39-26-42(63)52-20-11-10-18-35(43(50)64)56-45(66)37(24-32-23-31-15-8-9-17-34(31)55-32)59-48(69)41-19-12-21-61(41)49(70)40(22-30-13-6-5-7-14-30)60-46(67)38(57-47(39)68)25-33-27-51-28-53-33/h5-9,13-15,17,23,27-28,35-41,55H,3-4,10-12,16,18-22,24-26H2,1-2H3,(H2,50,64)(H,51,53)(H,52,63)(H,54,62)(H,56,66)(H,57,68)(H,58,65)(H,59,69)(H,60,67)/t35-,36-,37-,38-,39-,40+,41-/m0/s1 | PDB
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| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Homo sapiens (Human)) | BDBM50211392
(Ac-Nle4-cyclo(Asp5-Pro6-D-4,4'-Bip7-Pro8-Trp9-Lys1...)Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC(=O)[C@]1([H])CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C54H68N10O9/c1-3-4-17-41(58-33(2)65)49(68)61-44-31-47(66)56-26-11-10-19-40(48(55)67)59-50(69)42(30-37-32-57-39-18-9-8-16-38(37)39)60-51(70)45-20-12-27-63(45)53(72)43(62-52(71)46-21-13-28-64(46)54(44)73)29-34-22-24-36(25-23-34)35-14-6-5-7-15-35/h5-9,14-16,18,22-25,32,40-46,57H,3-4,10-13,17,19-21,26-31H2,1-2H3,(H2,55,67)(H,56,66)(H,58,65)(H,59,69)(H,60,70)(H,61,68)(H,62,71)/t40?,41-,42-,43-,44-,45-,46-/m0/s1 | PDB
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| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC3R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Homo sapiens (Human)) | BDBM50211389
(Ac-Nle4-cyclo(Asp5-His6-D-Tyr(Et)-Pro8-Trp9-Lys10)...)Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccc(O)cc2)N(CC)C(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C51H68N12O10/c1-4-6-13-38(56-30(3)64)46(68)59-40-27-44(66)54-21-10-9-15-37(45(52)67)58-47(69)39(25-33-24-32-12-7-8-14-36(32)57-33)60-49(71)42-16-11-22-63(42)51(73)43(23-31-17-19-35(65)20-18-31)62(5-2)50(72)41(61-48(40)70)26-34-28-53-29-55-34/h7-8,12,14,17-20,24,28-29,37-43,57,65H,4-6,9-11,13,15-16,21-23,25-27H2,1-3H3,(H2,52,67)(H,53,55)(H,54,66)(H,56,64)(H,58,69)(H,59,68)(H,60,71)(H,61,70)/t37-,38-,39-,40-,41-,42-,43+/m0/s1 | PDB
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| n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Homo sapiens (Human)) | BDBM50211366
(Ac-Nle4-cyclo(Asp5-His6-D-Bth-Pro8-Trp9-Lys10)-NH2...)Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2cc3ccccc3s2)N(CC)C(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C53H68N12O9S/c1-4-6-16-39(58-31(3)66)48(69)61-41-28-46(67)56-21-12-11-18-38(47(54)68)60-49(70)40(25-34-23-32-14-7-9-17-37(32)59-34)62-51(72)43-19-13-22-65(43)53(74)44(27-36-24-33-15-8-10-20-45(33)75-36)64(5-2)52(73)42(63-50(41)71)26-35-29-55-30-57-35/h7-10,14-15,17,20,23-24,29-30,38-44,59H,4-6,11-13,16,18-19,21-22,25-28H2,1-3H3,(H2,54,68)(H,55,57)(H,56,67)(H,58,66)(H,60,70)(H,61,69)(H,62,72)(H,63,71)/t38-,39-,40-,41-,42-,43-,44+/m0/s1 | PDB
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| n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Homo sapiens (Human)) | BDBM50211394
(Ac-Nle4-cyclo(Asp5-His6-L-Phe-Pro8-Trp9-Lys10)-NH2...)Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C49H64N12O9/c1-3-4-16-36(54-29(2)62)44(65)58-39-26-42(63)52-20-11-10-18-35(43(50)64)56-45(66)37(24-32-23-31-15-8-9-17-34(31)55-32)59-48(69)41-19-12-21-61(41)49(70)40(22-30-13-6-5-7-14-30)60-46(67)38(57-47(39)68)25-33-27-51-28-53-33/h5-9,13-15,17,23,27-28,35-41,55H,3-4,10-12,16,18-22,24-26H2,1-2H3,(H2,50,64)(H,51,53)(H,52,63)(H,54,62)(H,56,66)(H,57,68)(H,58,65)(H,59,69)(H,60,67)/t35-,36-,37-,38-,39-,40-,41-/m0/s1 | PDB
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| n/a | n/a | 390 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50211389
(Ac-Nle4-cyclo(Asp5-His6-D-Tyr(Et)-Pro8-Trp9-Lys10)...)Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccc(O)cc2)N(CC)C(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C51H68N12O10/c1-4-6-13-38(56-30(3)64)46(68)59-40-27-44(66)54-21-10-9-15-37(45(52)67)58-47(69)39(25-33-24-32-12-7-8-14-36(32)57-33)60-49(71)42-16-11-22-63(42)51(73)43(23-31-17-19-35(65)20-18-31)62(5-2)50(72)41(61-48(40)70)26-34-28-53-29-55-34/h7-8,12,14,17-20,24,28-29,37-43,57,65H,4-6,9-11,13,15-16,21-23,25-27H2,1-3H3,(H2,52,67)(H,53,55)(H,54,66)(H,56,64)(H,58,69)(H,59,68)(H,60,71)(H,61,70)/t37-,38-,39-,40-,41-,42-,43+/m0/s1 | PDB
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Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50211376
(Ac-Nle4-cyclo(Asp5-His6-D-Tyr(Me)-Pro8-Trp9-Lys10)...)Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccc(O)cc2)N(C)C(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C50H66N12O10/c1-4-5-12-37(55-29(2)63)45(67)58-39-26-43(65)53-20-9-8-14-36(44(51)66)57-46(68)38(24-32-23-31-11-6-7-13-35(31)56-32)59-48(70)41-15-10-21-62(41)50(72)42(22-30-16-18-34(64)19-17-30)61(3)49(71)40(60-47(39)69)25-33-27-52-28-54-33/h6-7,11,13,16-19,23,27-28,36-42,56,64H,4-5,8-10,12,14-15,20-22,24-26H2,1-3H3,(H2,51,66)(H,52,54)(H,53,65)(H,55,63)(H,57,68)(H,58,67)(H,59,70)(H,60,69)/t36-,37-,38-,39-,40-,41-,42+/m0/s1 | PDB
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Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50211367
(Ac-Nle4-cyclo(Asp5-His6-D-Phe(4-Cl)-Pro8-Trp9-Lys1...)Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C49H63ClN12O9/c1-3-4-11-36(55-28(2)63)44(66)59-39-25-42(64)53-19-8-7-13-35(43(51)65)57-45(67)37(23-32-22-30-10-5-6-12-34(30)56-32)60-48(70)41-14-9-20-62(41)49(71)40(21-29-15-17-31(50)18-16-29)61-46(68)38(58-47(39)69)24-33-26-52-27-54-33/h5-6,10,12,15-18,22,26-27,35-41,56H,3-4,7-9,11,13-14,19-21,23-25H2,1-2H3,(H2,51,65)(H,52,54)(H,53,64)(H,55,63)(H,57,67)(H,58,69)(H,59,66)(H,60,70)(H,61,68)/t35-,36-,37-,38-,39-,40+,41-/m0/s1 | PDB
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Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Homo sapiens (Human)) | BDBM50211391
(Ac-Nle4-cyclo(Asp5-His6-D-Phe-Pro8-Trp9-Lys10)-NH2...)Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C49H64N12O9/c1-3-4-16-36(54-29(2)62)44(65)58-39-26-42(63)52-20-11-10-18-35(43(50)64)56-45(66)37(24-32-23-31-15-8-9-17-34(31)55-32)59-48(69)41-19-12-21-61(41)49(70)40(22-30-13-6-5-7-14-30)60-46(67)38(57-47(39)68)25-33-27-51-28-53-33/h5-9,13-15,17,23,27-28,35-41,55H,3-4,10-12,16,18-22,24-26H2,1-2H3,(H2,50,64)(H,51,53)(H,52,63)(H,54,62)(H,56,66)(H,57,68)(H,58,65)(H,59,69)(H,60,67)/t35-,36-,37-,38-,39-,40+,41-/m0/s1 | PDB
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| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC4R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Homo sapiens (Human)) | BDBM50211383
(Ac-Nle4-cyclo(Asp5-Pro6-D-4,4'-Bip7-Pip8-Trp9-Lys1...)Show SMILES [H][C@@]12CCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@]1([H])CCCN1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C55H70N10O9/c1-3-4-18-42(59-34(2)66)50(69)62-45-32-48(67)57-27-12-10-20-41(49(56)68)60-51(70)43(31-38-33-58-40-19-9-8-17-39(38)40)61-52(71)46-21-11-13-28-64(46)54(73)44(63-53(72)47-22-14-29-65(47)55(45)74)30-35-23-25-37(26-24-35)36-15-6-5-7-16-36/h5-9,15-17,19,23-26,33,41-47,58H,3-4,10-14,18,20-22,27-32H2,1-2H3,(H2,56,68)(H,57,67)(H,59,66)(H,60,70)(H,61,71)(H,62,69)(H,63,72)/t41?,42-,43-,44-,45-,46-,47-/m0/s1 | PDB
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Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC3R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Homo sapiens (Human)) | BDBM50211393
(Ac-Nle4-cyclo(Asp5-Oic6-D-4,4'-Bic7-Pip8-Trp9-Lys1...)Show SMILES [H][C@]12CC3CCCCC3N1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC(=O)[C@]1([H])CCCCN1C(=O)[C@H](CC1CCC(CC1)C1CCCCC1)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O |wU:48.53,25.27,1.0,wD:12.75,71.79,21.72,39.43,(24.36,-.05,;23.9,-1.86,;23.14,-.52,;21.63,-.82,;20.39,.09,;18.98,-.52,;18.8,-2.05,;20.04,-2.97,;21.45,-2.35,;22.86,-2.99,;22.16,-4.37,;20.7,-3.86,;21.86,-5.88,;21.98,-7.41,;22.51,-8.86,;21.14,-9.58,;23.4,-10.11,;24.61,-11.07,;26.02,-11.67,;27.55,-11.87,;29.08,-11.64,;30.48,-11.02,;31.67,-10.04,;32.55,-8.77,;33.92,-9.47,;33.05,-7.32,;34.56,-7.62,;35.06,-9.07,;34.17,-10.33,;35.09,-11.57,;36.55,-11.07,;37.89,-11.82,;39.21,-11.04,;39.19,-9.5,;37.85,-8.74,;36.53,-9.53,;33.14,-5.78,;32.82,-4.27,;34.26,-3.74,;32.09,-2.91,;33.8,-3.68,;33.59,-2.55,;34.03,-1.07,;32.97,.04,;31.47,-.32,;31.03,-1.8,;29.71,-1.01,;30.31,.41,;28.22,-.6,;28.42,.92,;27.2,1.86,;25.78,1.26,;24.55,2.2,;24.75,3.72,;26.17,4.32,;27.39,3.38,;23.52,4.66,;22.1,4.07,;20.88,5,;21.07,6.53,;22.5,7.12,;23.72,6.19,;26.68,-.62,;25.21,-1.05,;24.58,.36,;31.29,-12.33,;32.83,-12.28,;30.57,-13.69,;20.32,-5.78,;19.47,-7.07,;20.16,-8.45,;17.94,-6.98,;17.09,-8.26,;17.78,-9.64,;16.93,-10.93,;17.62,-12.3,;17.25,-5.6,;15.71,-5.51,;15.02,-4.13,;14.86,-6.79,)| Show InChI InChI=1S/C59H88N10O9/c1-3-4-20-45(63-36(2)70)54(73)66-48-34-52(71)61-29-14-12-22-44(53(60)72)64-55(74)46(32-41-35-62-43-21-10-9-19-42(41)43)65-56(75)50-24-13-15-30-68(50)58(77)47(31-37-25-27-39(28-26-37)38-16-6-5-7-17-38)67-57(76)51-33-40-18-8-11-23-49(40)69(51)59(48)78/h9-10,19,21,35,37-40,44-51,62H,3-8,11-18,20,22-34H2,1-2H3,(H2,60,72)(H,61,71)(H,63,70)(H,64,74)(H,65,75)(H,66,73)(H,67,76)/t37?,39?,40?,44?,45-,46-,47-,48-,49?,50-,51+/m0/s1 | PDB
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| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50211374
(CHEMBL2371967 | c-Nle4-cyclo(Asp5-Tic6-D-4,4'-Bip7...)Show SMILES [H][C@@]12CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@]1([H])Cc3ccccc3CN1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C60H72N10O9/c1-3-4-21-47(64-37(2)71)55(74)67-50-34-53(72)62-29-14-12-23-46(54(61)73)65-56(75)48(32-43-35-63-45-22-11-10-20-44(43)45)66-57(76)51-24-13-15-30-69(51)59(78)49(31-38-25-27-40(28-26-38)39-16-6-5-7-17-39)68-58(77)52-33-41-18-8-9-19-42(41)36-70(52)60(50)79/h5-11,16-20,22,25-28,35,46-52,63H,3-4,12-15,21,23-24,29-34,36H2,1-2H3,(H2,61,73)(H,62,72)(H,64,71)(H,65,75)(H,66,76)(H,67,74)(H,68,77)/t46?,47-,48-,49-,50-,51-,52-/m0/s1 | PDB
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| n/a | n/a | 710 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Homo sapiens (Human)) | BDBM50211374
(CHEMBL2371967 | c-Nle4-cyclo(Asp5-Tic6-D-4,4'-Bip7...)Show SMILES [H][C@@]12CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@]1([H])Cc3ccccc3CN1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C60H72N10O9/c1-3-4-21-47(64-37(2)71)55(74)67-50-34-53(72)62-29-14-12-23-46(54(61)73)65-56(75)48(32-43-35-63-45-22-11-10-20-44(43)45)66-57(76)51-24-13-15-30-69(51)59(78)49(31-38-25-27-40(28-26-38)39-16-6-5-7-17-39)68-58(77)52-33-41-18-8-9-19-42(41)36-70(52)60(50)79/h5-11,16-20,22,25-28,35,46-52,63H,3-4,12-15,21,23-24,29-34,36H2,1-2H3,(H2,61,73)(H,62,72)(H,64,71)(H,65,75)(H,66,76)(H,67,74)(H,68,77)/t46?,47-,48-,49-,50-,51-,52-/m0/s1 | PDB
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Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC4R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Homo sapiens (Human)) | BDBM50211388
(Ac-Nle4-cyclo(Asp5-His6-D-Phe(No2)-Pro8-Trp9-Lys10...)Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccc(cc2)[N+]([O-])=O)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C49H63N13O11/c1-3-4-11-36(54-28(2)63)44(66)58-39-25-42(64)52-19-8-7-13-35(43(50)65)56-45(67)37(23-31-22-30-10-5-6-12-34(30)55-31)59-48(70)41-14-9-20-61(41)49(71)40(21-29-15-17-33(18-16-29)62(72)73)60-46(68)38(57-47(39)69)24-32-26-51-27-53-32/h5-6,10,12,15-18,22,26-27,35-41,55H,3-4,7-9,11,13-14,19-21,23-25H2,1-2H3,(H2,50,65)(H,51,53)(H,52,64)(H,54,63)(H,56,67)(H,57,69)(H,58,66)(H,59,70)(H,60,68)/t35-,36-,37-,38-,39-,40+,41-/m0/s1 | PDB
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| n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Homo sapiens (Human)) | BDBM50211394
(Ac-Nle4-cyclo(Asp5-His6-L-Phe-Pro8-Trp9-Lys10)-NH2...)Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C49H64N12O9/c1-3-4-16-36(54-29(2)62)44(65)58-39-26-42(63)52-20-11-10-18-35(43(50)64)56-45(66)37(24-32-23-31-15-8-9-17-34(31)55-32)59-48(69)41-19-12-21-61(41)49(70)40(22-30-13-6-5-7-14-30)60-46(67)38(57-47(39)68)25-33-27-51-28-53-33/h5-9,13-15,17,23,27-28,35-41,55H,3-4,10-12,16,18-22,24-26H2,1-2H3,(H2,50,64)(H,51,53)(H,52,63)(H,54,62)(H,56,66)(H,57,68)(H,58,65)(H,59,69)(H,60,67)/t35-,36-,37-,38-,39-,40-,41-/m0/s1 | PDB
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| n/a | n/a | 860 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC3R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50211380
(Ac-Nle4-cyclo(Asp5-His6-D-Nal(2)-Pro8-Trp9-Lys10)-...)Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C53H66N12O9/c1-3-4-15-40(58-31(2)66)48(69)62-43-28-46(67)56-21-10-9-17-39(47(54)68)60-49(70)41(26-36-25-35-14-7-8-16-38(35)59-36)63-52(73)45-18-11-22-65(45)53(74)44(24-32-19-20-33-12-5-6-13-34(33)23-32)64-50(71)42(61-51(43)72)27-37-29-55-30-57-37/h5-8,12-14,16,19-20,23,25,29-30,39-45,59H,3-4,9-11,15,17-18,21-22,24,26-28H2,1-2H3,(H2,54,68)(H,55,57)(H,56,67)(H,58,66)(H,60,70)(H,61,72)(H,62,69)(H,63,73)(H,64,71)/t39-,40-,41-,42-,43-,44+,45-/m0/s1 | PDB
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Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50211394
(Ac-Nle4-cyclo(Asp5-His6-L-Phe-Pro8-Trp9-Lys10)-NH2...)Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C49H64N12O9/c1-3-4-16-36(54-29(2)62)44(65)58-39-26-42(63)52-20-11-10-18-35(43(50)64)56-45(66)37(24-32-23-31-15-8-9-17-34(31)55-32)59-48(69)41-19-12-21-61(41)49(70)40(22-30-13-6-5-7-14-30)60-46(67)38(57-47(39)68)25-33-27-51-28-53-33/h5-9,13-15,17,23,27-28,35-41,55H,3-4,10-12,16,18-22,24-26H2,1-2H3,(H2,50,64)(H,51,53)(H,52,63)(H,54,62)(H,56,66)(H,57,68)(H,58,65)(H,59,69)(H,60,67)/t35-,36-,37-,38-,39-,40-,41-/m0/s1 | PDB
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Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Homo sapiens (Human)) | BDBM50211395
(Ac-Nle4-cyclo(Asp5-Phg6-D-4,4'-Bip7-Pip8-Trp9-Lys1...)Show SMILES [H][C@@]12CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O)c1ccccc1 Show InChI InChI=1S/C58H70N10O9/c1-3-4-22-45(62-36(2)69)53(72)64-47-34-50(70)60-30-15-13-24-44(52(59)71)63-54(73)46(33-41-35-61-43-23-12-11-21-42(41)43)65-56(75)49-25-14-16-31-68(49)58(77)48(32-37-26-28-39(29-27-37)38-17-7-5-8-18-38)66-57(76)51(67-55(47)74)40-19-9-6-10-20-40/h5-12,17-21,23,26-29,35,44-49,51,61H,3-4,13-16,22,24-25,30-34H2,1-2H3,(H2,59,71)(H,60,70)(H,62,69)(H,63,73)(H,64,72)(H,65,75)(H,66,76)(H,67,74)/t44?,45-,46-,47-,48-,49-,51-/m0/s1 | PDB
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| n/a | n/a | 990 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Homo sapiens (Human)) | BDBM50211395
(Ac-Nle4-cyclo(Asp5-Phg6-D-4,4'-Bip7-Pip8-Trp9-Lys1...)Show SMILES [H][C@@]12CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O)c1ccccc1 Show InChI InChI=1S/C58H70N10O9/c1-3-4-22-45(62-36(2)69)53(72)64-47-34-50(70)60-30-15-13-24-44(52(59)71)63-54(73)46(33-41-35-61-43-23-12-11-21-42(41)43)65-56(75)49-25-14-16-31-68(49)58(77)48(32-37-26-28-39(29-27-37)38-17-7-5-8-18-38)66-57(76)51(67-55(47)74)40-19-9-6-10-20-40/h5-12,17-21,23,26-29,35,44-49,51,61H,3-4,13-16,22,24-25,30-34H2,1-2H3,(H2,59,71)(H,60,70)(H,62,69)(H,63,73)(H,64,72)(H,65,75)(H,66,76)(H,67,74)/t44?,45-,46-,47-,48-,49-,51-/m0/s1 | PDB
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| n/a | n/a | 990 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC4R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Homo sapiens (Human)) | BDBM50211391
(Ac-Nle4-cyclo(Asp5-His6-D-Phe-Pro8-Trp9-Lys10)-NH2...)Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C49H64N12O9/c1-3-4-16-36(54-29(2)62)44(65)58-39-26-42(63)52-20-11-10-18-35(43(50)64)56-45(66)37(24-32-23-31-15-8-9-17-34(31)55-32)59-48(69)41-19-12-21-61(41)49(70)40(22-30-13-6-5-7-14-30)60-46(67)38(57-47(39)68)25-33-27-51-28-53-33/h5-9,13-15,17,23,27-28,35-41,55H,3-4,10-12,16,18-22,24-26H2,1-2H3,(H2,50,64)(H,51,53)(H,52,63)(H,54,62)(H,56,66)(H,57,68)(H,58,65)(H,59,69)(H,60,67)/t35-,36-,37-,38-,39-,40+,41-/m0/s1 | PDB
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| n/a | n/a | 990 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC3R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Homo sapiens (Human)) | BDBM50211370
(Ac-Nle4-cyclo(Asp5-Oic6-D-D-pBzlPhe7-Pip8-Trp9-Lys...)Show SMILES [H][C@@]12CC3CCCCC3N1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC(=O)[C@]1([H])CCCCN1C(=O)[C@H](Cc1ccc(Cc3ccccc3)cc1)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C60H78N10O9/c1-3-4-20-46(64-37(2)71)55(74)67-49-35-53(72)62-29-14-12-22-45(54(61)73)65-56(75)47(33-42-36-63-44-21-10-9-19-43(42)44)66-57(76)51-24-13-15-30-69(51)59(78)48(32-40-27-25-39(26-28-40)31-38-16-6-5-7-17-38)68-58(77)52-34-41-18-8-11-23-50(41)70(52)60(49)79/h5-7,9-10,16-17,19,21,25-28,36,41,45-52,63H,3-4,8,11-15,18,20,22-24,29-35H2,1-2H3,(H2,61,73)(H,62,72)(H,64,71)(H,65,75)(H,66,76)(H,67,74)(H,68,77)/t41?,45?,46-,47-,48-,49-,50?,51-,52-/m0/s1 | PDB
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| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC3R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Homo sapiens (Human)) | BDBM50211393
(Ac-Nle4-cyclo(Asp5-Oic6-D-4,4'-Bic7-Pip8-Trp9-Lys1...)Show SMILES [H][C@]12CC3CCCCC3N1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC(=O)[C@]1([H])CCCCN1C(=O)[C@H](CC1CCC(CC1)C1CCCCC1)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O |wU:48.53,25.27,1.0,wD:12.75,71.79,21.72,39.43,(24.36,-.05,;23.9,-1.86,;23.14,-.52,;21.63,-.82,;20.39,.09,;18.98,-.52,;18.8,-2.05,;20.04,-2.97,;21.45,-2.35,;22.86,-2.99,;22.16,-4.37,;20.7,-3.86,;21.86,-5.88,;21.98,-7.41,;22.51,-8.86,;21.14,-9.58,;23.4,-10.11,;24.61,-11.07,;26.02,-11.67,;27.55,-11.87,;29.08,-11.64,;30.48,-11.02,;31.67,-10.04,;32.55,-8.77,;33.92,-9.47,;33.05,-7.32,;34.56,-7.62,;35.06,-9.07,;34.17,-10.33,;35.09,-11.57,;36.55,-11.07,;37.89,-11.82,;39.21,-11.04,;39.19,-9.5,;37.85,-8.74,;36.53,-9.53,;33.14,-5.78,;32.82,-4.27,;34.26,-3.74,;32.09,-2.91,;33.8,-3.68,;33.59,-2.55,;34.03,-1.07,;32.97,.04,;31.47,-.32,;31.03,-1.8,;29.71,-1.01,;30.31,.41,;28.22,-.6,;28.42,.92,;27.2,1.86,;25.78,1.26,;24.55,2.2,;24.75,3.72,;26.17,4.32,;27.39,3.38,;23.52,4.66,;22.1,4.07,;20.88,5,;21.07,6.53,;22.5,7.12,;23.72,6.19,;26.68,-.62,;25.21,-1.05,;24.58,.36,;31.29,-12.33,;32.83,-12.28,;30.57,-13.69,;20.32,-5.78,;19.47,-7.07,;20.16,-8.45,;17.94,-6.98,;17.09,-8.26,;17.78,-9.64,;16.93,-10.93,;17.62,-12.3,;17.25,-5.6,;15.71,-5.51,;15.02,-4.13,;14.86,-6.79,)| Show InChI InChI=1S/C59H88N10O9/c1-3-4-20-45(63-36(2)70)54(73)66-48-34-52(71)61-29-14-12-22-44(53(60)72)64-55(74)46(32-41-35-62-43-21-10-9-19-42(41)43)65-56(75)50-24-13-15-30-68(50)58(77)47(31-37-25-27-39(28-26-37)38-16-6-5-7-17-38)67-57(76)51-33-40-18-8-11-23-49(40)69(51)59(48)78/h9-10,19,21,35,37-40,44-51,62H,3-8,11-18,20,22-34H2,1-2H3,(H2,60,72)(H,61,71)(H,63,70)(H,64,74)(H,65,75)(H,66,73)(H,67,76)/t37?,39?,40?,44?,45-,46-,47-,48-,49?,50-,51+/m0/s1 | PDB
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| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC3R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Homo sapiens (Human)) | BDBM50211395
(Ac-Nle4-cyclo(Asp5-Phg6-D-4,4'-Bip7-Pip8-Trp9-Lys1...)Show SMILES [H][C@@]12CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O)c1ccccc1 Show InChI InChI=1S/C58H70N10O9/c1-3-4-22-45(62-36(2)69)53(72)64-47-34-50(70)60-30-15-13-24-44(52(59)71)63-54(73)46(33-41-35-61-43-23-12-11-21-42(41)43)65-56(75)49-25-14-16-31-68(49)58(77)48(32-37-26-28-39(29-27-37)38-17-7-5-8-18-38)66-57(76)51(67-55(47)74)40-19-9-6-10-20-40/h5-12,17-21,23,26-29,35,44-49,51,61H,3-4,13-16,22,24-25,30-34H2,1-2H3,(H2,59,71)(H,60,70)(H,62,69)(H,63,73)(H,64,72)(H,65,75)(H,66,76)(H,67,74)/t44?,45-,46-,47-,48-,49-,51-/m0/s1 | PDB
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| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC3R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Homo sapiens (Human)) | BDBM50211383
(Ac-Nle4-cyclo(Asp5-Pro6-D-4,4'-Bip7-Pip8-Trp9-Lys1...)Show SMILES [H][C@@]12CCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@]1([H])CCCN1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C55H70N10O9/c1-3-4-18-42(59-34(2)66)50(69)62-45-32-48(67)57-27-12-10-20-41(49(56)68)60-51(70)43(31-38-33-58-40-19-9-8-17-39(38)40)61-52(71)46-21-11-13-28-64(46)54(73)44(63-53(72)47-22-14-29-65(47)55(45)74)30-35-23-25-37(26-24-35)36-15-6-5-7-16-36/h5-9,15-17,19,23-26,33,41-47,58H,3-4,10-14,18,20-22,27-32H2,1-2H3,(H2,56,68)(H,57,67)(H,59,66)(H,60,70)(H,61,71)(H,62,69)(H,63,72)/t41?,42-,43-,44-,45-,46-,47-/m0/s1 | PDB
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| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50211395
(Ac-Nle4-cyclo(Asp5-Phg6-D-4,4'-Bip7-Pip8-Trp9-Lys1...)Show SMILES [H][C@@]12CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O)c1ccccc1 Show InChI InChI=1S/C58H70N10O9/c1-3-4-22-45(62-36(2)69)53(72)64-47-34-50(70)60-30-15-13-24-44(52(59)71)63-54(73)46(33-41-35-61-43-23-12-11-21-42(41)43)65-56(75)49-25-14-16-31-68(49)58(77)48(32-37-26-28-39(29-27-37)38-17-7-5-8-18-38)66-57(76)51(67-55(47)74)40-19-9-6-10-20-40/h5-12,17-21,23,26-29,35,44-49,51,61H,3-4,13-16,22,24-25,30-34H2,1-2H3,(H2,59,71)(H,60,70)(H,62,69)(H,63,73)(H,64,72)(H,65,75)(H,66,76)(H,67,74)/t44?,45-,46-,47-,48-,49-,51-/m0/s1 | PDB
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PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50211383
(Ac-Nle4-cyclo(Asp5-Pro6-D-4,4'-Bip7-Pip8-Trp9-Lys1...)Show SMILES [H][C@@]12CCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@]1([H])CCCN1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C55H70N10O9/c1-3-4-18-42(59-34(2)66)50(69)62-45-32-48(67)57-27-12-10-20-41(49(56)68)60-51(70)43(31-38-33-58-40-19-9-8-17-39(38)40)61-52(71)46-21-11-13-28-64(46)54(73)44(63-53(72)47-22-14-29-65(47)55(45)74)30-35-23-25-37(26-24-35)36-15-6-5-7-16-36/h5-9,15-17,19,23-26,33,41-47,58H,3-4,10-14,18,20-22,27-32H2,1-2H3,(H2,56,68)(H,57,67)(H,59,66)(H,60,70)(H,61,71)(H,62,69)(H,63,72)/t41?,42-,43-,44-,45-,46-,47-/m0/s1 | PDB
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| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50211370
(Ac-Nle4-cyclo(Asp5-Oic6-D-D-pBzlPhe7-Pip8-Trp9-Lys...)Show SMILES [H][C@@]12CC3CCCCC3N1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC(=O)[C@]1([H])CCCCN1C(=O)[C@H](Cc1ccc(Cc3ccccc3)cc1)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C60H78N10O9/c1-3-4-20-46(64-37(2)71)55(74)67-49-35-53(72)62-29-14-12-22-45(54(61)73)65-56(75)47(33-42-36-63-44-21-10-9-19-43(42)44)66-57(76)51-24-13-15-30-69(51)59(78)48(32-40-27-25-39(26-28-40)31-38-16-6-5-7-17-38)68-58(77)52-34-41-18-8-11-23-50(41)70(52)60(49)79/h5-7,9-10,16-17,19,21,25-28,36,41,45-52,63H,3-4,8,11-15,18,20,22-24,29-35H2,1-2H3,(H2,61,73)(H,62,72)(H,64,71)(H,65,75)(H,66,76)(H,67,74)(H,68,77)/t41?,45?,46-,47-,48-,49-,50?,51-,52-/m0/s1 | PDB
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Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Homo sapiens (Human)) | BDBM50211383
(Ac-Nle4-cyclo(Asp5-Pro6-D-4,4'-Bip7-Pip8-Trp9-Lys1...)Show SMILES [H][C@@]12CCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@]1([H])CCCN1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C55H70N10O9/c1-3-4-18-42(59-34(2)66)50(69)62-45-32-48(67)57-27-12-10-20-41(49(56)68)60-51(70)43(31-38-33-58-40-19-9-8-17-39(38)40)61-52(71)46-21-11-13-28-64(46)54(73)44(63-53(72)47-22-14-29-65(47)55(45)74)30-35-23-25-37(26-24-35)36-15-6-5-7-16-36/h5-9,15-17,19,23-26,33,41-47,58H,3-4,10-14,18,20-22,27-32H2,1-2H3,(H2,56,68)(H,57,67)(H,59,66)(H,60,70)(H,61,71)(H,62,69)(H,63,72)/t41?,42-,43-,44-,45-,46-,47-/m0/s1 | PDB
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| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC4R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Homo sapiens (Human)) | BDBM50211377
(Ac-Nle4-cyclo(Asp5-His6-D-4,4'-Bip-Pro8-Trp9-Lys10...)Show SMILES CCCC[C@H](NC(C)=O)C(=O)C[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccc(cc2)-c2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C56H69N11O9/c1-3-4-16-43(61-34(2)68)49(69)28-39-29-50(70)59-24-11-10-18-44(51(57)71)63-53(73)45(30-40-27-38-15-8-9-17-42(38)62-40)65-55(75)48-19-12-25-67(48)56(76)47(26-35-20-22-37(23-21-35)36-13-6-5-7-14-36)66-54(74)46(64-52(39)72)31-41-32-58-33-60-41/h5-9,13-15,17,20-23,27,32-33,39,43-48,62H,3-4,10-12,16,18-19,24-26,28-31H2,1-2H3,(H2,57,71)(H,58,60)(H,59,70)(H,61,68)(H,63,73)(H,64,72)(H,65,75)(H,66,74)/t39-,43-,44-,45-,46-,47+,48-/m0/s1 | PDB
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| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC4R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50211393
(Ac-Nle4-cyclo(Asp5-Oic6-D-4,4'-Bic7-Pip8-Trp9-Lys1...)Show SMILES [H][C@]12CC3CCCCC3N1C(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC(=O)[C@]1([H])CCCCN1C(=O)[C@H](CC1CCC(CC1)C1CCCCC1)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O |wU:48.53,25.27,1.0,wD:12.75,71.79,21.72,39.43,(24.36,-.05,;23.9,-1.86,;23.14,-.52,;21.63,-.82,;20.39,.09,;18.98,-.52,;18.8,-2.05,;20.04,-2.97,;21.45,-2.35,;22.86,-2.99,;22.16,-4.37,;20.7,-3.86,;21.86,-5.88,;21.98,-7.41,;22.51,-8.86,;21.14,-9.58,;23.4,-10.11,;24.61,-11.07,;26.02,-11.67,;27.55,-11.87,;29.08,-11.64,;30.48,-11.02,;31.67,-10.04,;32.55,-8.77,;33.92,-9.47,;33.05,-7.32,;34.56,-7.62,;35.06,-9.07,;34.17,-10.33,;35.09,-11.57,;36.55,-11.07,;37.89,-11.82,;39.21,-11.04,;39.19,-9.5,;37.85,-8.74,;36.53,-9.53,;33.14,-5.78,;32.82,-4.27,;34.26,-3.74,;32.09,-2.91,;33.8,-3.68,;33.59,-2.55,;34.03,-1.07,;32.97,.04,;31.47,-.32,;31.03,-1.8,;29.71,-1.01,;30.31,.41,;28.22,-.6,;28.42,.92,;27.2,1.86,;25.78,1.26,;24.55,2.2,;24.75,3.72,;26.17,4.32,;27.39,3.38,;23.52,4.66,;22.1,4.07,;20.88,5,;21.07,6.53,;22.5,7.12,;23.72,6.19,;26.68,-.62,;25.21,-1.05,;24.58,.36,;31.29,-12.33,;32.83,-12.28,;30.57,-13.69,;20.32,-5.78,;19.47,-7.07,;20.16,-8.45,;17.94,-6.98,;17.09,-8.26,;17.78,-9.64,;16.93,-10.93,;17.62,-12.3,;17.25,-5.6,;15.71,-5.51,;15.02,-4.13,;14.86,-6.79,)| Show InChI InChI=1S/C59H88N10O9/c1-3-4-20-45(63-36(2)70)54(73)66-48-34-52(71)61-29-14-12-22-44(53(60)72)64-55(74)46(32-41-35-62-43-21-10-9-19-42(41)43)65-56(75)50-24-13-15-30-68(50)58(77)47(31-37-25-27-39(28-26-37)38-16-6-5-7-17-38)67-57(76)51-33-40-18-8-11-23-49(40)69(51)59(48)78/h9-10,19,21,35,37-40,44-51,62H,3-8,11-18,20,22-34H2,1-2H3,(H2,60,72)(H,61,71)(H,63,70)(H,64,74)(H,65,75)(H,66,73)(H,67,76)/t37?,39?,40?,44?,45-,46-,47-,48-,49?,50-,51+/m0/s1 | PDB
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| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Homo sapiens (Human)) | BDBM50211367
(Ac-Nle4-cyclo(Asp5-His6-D-Phe(4-Cl)-Pro8-Trp9-Lys1...)Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C49H63ClN12O9/c1-3-4-11-36(55-28(2)63)44(66)59-39-25-42(64)53-19-8-7-13-35(43(51)65)57-45(67)37(23-32-22-30-10-5-6-12-34(30)56-32)60-48(70)41-14-9-20-62(41)49(71)40(21-29-15-17-31(50)18-16-29)61-46(68)38(58-47(39)69)24-33-26-52-27-54-33/h5-6,10,12,15-18,22,26-27,35-41,56H,3-4,7-9,11,13-14,19-21,23-25H2,1-2H3,(H2,51,65)(H,52,54)(H,53,64)(H,55,63)(H,57,67)(H,58,69)(H,59,66)(H,60,70)(H,61,68)/t35-,36-,37-,38-,39-,40+,41-/m0/s1 | PDB
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| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Homo sapiens (Human)) | BDBM50211375
(Ac-Nle4-cyclo(Asp5-His6-D-4,4'-Bip7-Pip8-Trp9-Lys1...)Show SMILES [H][C@@]12CCCCN1C(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC2=O)C(N)=O)NC(=O)[C@H](CCCC)NC(C)=O Show InChI InChI=1S/C56H70N12O9/c1-3-4-17-43(62-34(2)69)51(72)65-46-30-49(70)59-25-12-10-19-42(50(57)71)63-52(73)44(28-38-31-60-41-18-9-8-16-40(38)41)66-55(76)48-20-11-13-26-68(48)56(77)47(27-35-21-23-37(24-22-35)36-14-6-5-7-15-36)67-53(74)45(64-54(46)75)29-39-32-58-33-61-39/h5-9,14-16,18,21-24,31-33,42-48,60H,3-4,10-13,17,19-20,25-30H2,1-2H3,(H2,57,71)(H,58,61)(H,59,70)(H,62,69)(H,63,73)(H,64,75)(H,65,72)(H,66,76)(H,67,74)/t42?,43-,44-,45-,46-,47-,48-/m0/s1 | PDB
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| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC3R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Homo sapiens (Human)) | BDBM50211377
(Ac-Nle4-cyclo(Asp5-His6-D-4,4'-Bip-Pro8-Trp9-Lys10...)Show SMILES CCCC[C@H](NC(C)=O)C(=O)C[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccc(cc2)-c2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C56H69N11O9/c1-3-4-16-43(61-34(2)68)49(69)28-39-29-50(70)59-24-11-10-18-44(51(57)71)63-53(73)45(30-40-27-38-15-8-9-17-42(38)62-40)65-55(75)48-19-12-25-67(48)56(76)47(26-35-20-22-37(23-21-35)36-13-6-5-7-14-36)66-54(74)46(64-52(39)72)31-41-32-58-33-60-41/h5-9,13-15,17,20-23,27,32-33,39,43-48,62H,3-4,10-12,16,18-19,24-26,28-31H2,1-2H3,(H2,57,71)(H,58,60)(H,59,70)(H,61,68)(H,63,73)(H,64,72)(H,65,75)(H,66,74)/t39-,43-,44-,45-,46-,47+,48-/m0/s1 | PDB
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| n/a | n/a | >1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]NDPalphaMSH from human cloned MC3R expressed in CHO cells |
J Med Chem 50: 2520-6 (2007)
Article DOI: 10.1021/jm0614275
BindingDB Entry DOI: 10.7270/Q2JQ10QM |
More data for this
Ligand-Target Pair | |
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