Compile Data Set for Download or QSAR

Found 75 hits Enz. Inhib. hit(s) with all data for entry = 50034391   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase 3 (Homo sapiens (Human))	BDBM50361618 (CHEMBL1939876 | US8785489, 4-{[({5-[2-(ethoxycarbo...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H22N4O5/c1-3-33-24(32)20-11-17-10-16(8-9-18(17)26-20)21-12-19(27-28(21)2)22(29)25-13-14-4-6-15(7-5-14)23(30)31/h4-12,26H,3,13H2,1-2H3,(H,25,29)(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human MMP13 expressed in Escherichia coli after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair				3D Structure (crystal)
Collagenase 3 (Homo sapiens (Human))	BDBM50361634 (CHEMBL1939877 | US8785489, (4-{[({5-[2-(ethoxycarb...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccc(CC(O)=O)cc1 Show InChI InChI=1S/C25H24N4O5/c1-3-34-25(33)21-12-18-11-17(8-9-19(18)27-21)22-13-20(28-29(22)2)24(32)26-14-16-6-4-15(5-7-16)10-23(30)31/h4-9,11-13,27H,3,10,14H2,1-2H3,(H,26,32)(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human MMP13 expressed in Escherichia coli after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50361618 (CHEMBL1939876 | US8785489, 4-{[({5-[2-(ethoxycarbo...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H22N4O5/c1-3-33-24(32)20-11-17-10-16(8-9-18(17)26-20)21-12-19(27-28(21)2)22(29)25-13-14-4-6-15(7-5-14)23(30)31/h4-12,26H,3,13H2,1-2H3,(H,25,29)(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of MMP13 after 30 mins by fluorimetry in the presence of 1.25% human serum albumin				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair				3D Structure (crystal)
Collagenase 3 (Homo sapiens (Human))	BDBM50361618 (CHEMBL1939876 | US8785489, 4-{[({5-[2-(ethoxycarbo...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H22N4O5/c1-3-33-24(32)20-11-17-10-16(8-9-18(17)26-20)21-12-19(27-28(21)2)22(29)25-13-14-4-6-15(7-5-14)23(30)31/h4-12,26H,3,13H2,1-2H3,(H,25,29)(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of AMPA-activated MMP13-mediated degradation of FITC-labeled type2 collagen after 1.5 hrs by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair				3D Structure (crystal)
Collagenase 3 (Homo sapiens (Human))	BDBM50361634 (CHEMBL1939877 | US8785489, (4-{[({5-[2-(ethoxycarb...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccc(CC(O)=O)cc1 Show InChI InChI=1S/C25H24N4O5/c1-3-34-25(33)21-12-18-11-17(8-9-19(18)27-21)22-13-20(28-29(22)2)24(32)26-14-16-6-4-15(5-7-16)10-23(30)31/h4-9,11-13,27H,3,10,14H2,1-2H3,(H,26,32)(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of MMP13 after 30 mins by fluorimetry in the presence of 1.25% human serum albumin				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50361618 (CHEMBL1939876 | US8785489, 4-{[({5-[2-(ethoxycarbo...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H22N4O5/c1-3-33-24(32)20-11-17-10-16(8-9-18(17)26-20)21-12-19(27-28(21)2)22(29)25-13-14-4-6-15(7-5-14)23(30)31/h4-12,26H,3,13H2,1-2H3,(H,25,29)(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human MMP13-mediated degradation of bovine nasal cartilage after 2 hrs by ELISA in the presence of 10% human serum				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair				3D Structure (crystal)
Collagenase 3 (Homo sapiens (Human))	BDBM50361632 (CHEMBL1939874 | US8785489, ethyl 5-{1-methyl-3-[(p...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccncc1 Show InChI InChI=1S/C22H21N5O3/c1-3-30-22(29)19-11-16-10-15(4-5-17(16)25-19)20-12-18(26-27(20)2)21(28)24-13-14-6-8-23-9-7-14/h4-12,25H,3,13H2,1-2H3,(H,24,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human MMP13 expressed in Escherichia coli after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50361633 (CHEMBL1939875 | US8785489, ethyl 5-(1-methyl-3-{[(...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccc(=O)[nH]c1 Show InChI InChI=1S/C22H21N5O4/c1-3-31-22(30)18-9-15-8-14(5-6-16(15)25-18)19-10-17(26-27(19)2)21(29)24-12-13-4-7-20(28)23-11-13/h4-11,25H,3,12H2,1-2H3,(H,23,28)(H,24,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human MMP13 expressed in Escherichia coli after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50361635 (CHEMBL1939878 | US8785489, ethyl 5-{5-methyl-2-[(p...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(ncc1C)C(=O)NCc1ccncc1 Show InChI InChI=1S/C24H22N4O3/c1-3-31-24(30)22-11-18-10-17(4-5-20(18)28-22)19-12-21(26-13-15(19)2)23(29)27-14-16-6-8-25-9-7-16/h4-13,28H,3,14H2,1-2H3,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human MMP13 expressed in Escherichia coli after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50361638 (CHEMBL1939881) Show SMILES CCOCc1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H24N4O4/c1-3-32-14-19-11-18-10-17(8-9-20(18)26-19)22-12-21(27-28(22)2)23(29)25-13-15-4-6-16(7-5-15)24(30)31/h4-12,26H,3,13-14H2,1-2H3,(H,25,29)(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human MMP13 expressed in Escherichia coli after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50361633 (CHEMBL1939875 | US8785489, ethyl 5-(1-methyl-3-{[(...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccc(=O)[nH]c1 Show InChI InChI=1S/C22H21N5O4/c1-3-31-22(30)18-9-15-8-14(5-6-16(15)25-18)19-10-17(26-27(19)2)21(29)24-12-13-4-7-20(28)23-11-13/h4-11,25H,3,12H2,1-2H3,(H,23,28)(H,24,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of MMP13 after 30 mins by fluorimetry in the presence of 1.25% human serum albumin				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50361632 (CHEMBL1939874 | US8785489, ethyl 5-{1-methyl-3-[(p...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccncc1 Show InChI InChI=1S/C22H21N5O3/c1-3-30-22(29)19-11-16-10-15(4-5-17(16)25-19)20-12-18(26-27(20)2)21(28)24-13-14-6-8-23-9-7-14/h4-12,25H,3,13H2,1-2H3,(H,24,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of MMP13 after 30 mins by fluorimetry in the presence of 1.25% human serum albumin				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50361635 (CHEMBL1939878 | US8785489, ethyl 5-{5-methyl-2-[(p...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(ncc1C)C(=O)NCc1ccncc1 Show InChI InChI=1S/C24H22N4O3/c1-3-31-24(30)22-11-18-10-17(4-5-20(18)28-22)19-12-21(26-13-15(19)2)23(29)27-14-16-6-8-25-9-7-16/h4-13,28H,3,14H2,1-2H3,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of MMP13 after 30 mins by fluorimetry in the presence of 1.25% human serum albumin				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50361638 (CHEMBL1939881) Show SMILES CCOCc1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H24N4O4/c1-3-32-14-19-11-18-10-17(8-9-20(18)26-19)22-12-21(27-28(22)2)23(29)25-13-15-4-6-16(7-5-15)24(30)31/h4-12,26H,3,13-14H2,1-2H3,(H,25,29)(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of MMP13 after 30 mins by fluorimetry in the presence of 1.25% human serum albumin				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50361631 (CHEMBL1939873) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)OC Show InChI InChI=1S/C17H17N3O4/c1-4-24-17(22)13-8-11-7-10(5-6-12(11)18-13)15-9-14(16(21)23-3)19-20(15)2/h5-9,18H,4H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human MMP13 expressed in Escherichia coli after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50361630 (CHEMBL1939872) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cncn1C Show InChI InChI=1S/C15H15N3O2/c1-3-20-15(19)13-7-11-6-10(4-5-12(11)17-13)14-8-16-9-18(14)2/h4-9,17H,3H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human MMP13 expressed in Escherichia coli after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair				3D Structure (crystal)
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50361618 (CHEMBL1939876 | US8785489, 4-{[({5-[2-(ethoxycarbo...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H22N4O5/c1-3-33-24(32)20-11-17-10-16(8-9-18(17)26-20)21-12-19(27-28(21)2)22(29)25-13-14-4-6-15(7-5-14)23(30)31/h4-12,26H,3,13H2,1-2H3,(H,25,29)(H,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP14 after 60 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50361618 (CHEMBL1939876 | US8785489, 4-{[({5-[2-(ethoxycarbo...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H22N4O5/c1-3-33-24(32)20-11-17-10-16(8-9-18(17)26-20)21-12-19(27-28(21)2)22(29)25-13-14-4-6-15(7-5-14)23(30)31/h4-12,26H,3,13H2,1-2H3,(H,25,29)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP9 after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50361629 (CHEMBL1939871) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1ccncc1C Show InChI InChI=1S/C17H16N2O2/c1-3-21-17(20)16-9-13-8-12(4-5-15(13)19-16)14-6-7-18-10-11(14)2/h4-10,19H,3H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human MMP13 expressed in Escherichia coli after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50361633 (CHEMBL1939875 | US8785489, ethyl 5-(1-methyl-3-{[(...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccc(=O)[nH]c1 Show InChI InChI=1S/C22H21N5O4/c1-3-31-22(30)18-9-15-8-14(5-6-16(15)25-18)19-10-17(26-27(19)2)21(29)24-12-13-4-7-20(28)23-11-13/h4-11,25H,3,12H2,1-2H3,(H,23,28)(H,24,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP14 after 60 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50361630 (CHEMBL1939872) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cncn1C Show InChI InChI=1S/C15H15N3O2/c1-3-20-15(19)13-7-11-6-10(4-5-12(11)17-13)14-8-16-9-18(14)2/h4-9,17H,3H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP14 after 60 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50361627 (CHEMBL1939869) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cccnc1 Show InChI InChI=1S/C16H14N2O2/c1-2-20-16(19)15-9-13-8-11(5-6-14(13)18-15)12-4-3-7-17-10-12/h3-10,18H,2H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human MMP13 expressed in Escherichia coli after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50361618 (CHEMBL1939876 | US8785489, 4-{[({5-[2-(ethoxycarbo...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H22N4O5/c1-3-33-24(32)20-11-17-10-16(8-9-18(17)26-20)21-12-19(27-28(21)2)22(29)25-13-14-4-6-15(7-5-14)23(30)31/h4-12,26H,3,13H2,1-2H3,(H,25,29)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP10 after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50361618 (CHEMBL1939876 | US8785489, 4-{[({5-[2-(ethoxycarbo...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H22N4O5/c1-3-33-24(32)20-11-17-10-16(8-9-18(17)26-20)21-12-19(27-28(21)2)22(29)25-13-14-4-6-15(7-5-14)23(30)31/h4-12,26H,3,13H2,1-2H3,(H,25,29)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50361635 (CHEMBL1939878 | US8785489, ethyl 5-{5-methyl-2-[(p...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(ncc1C)C(=O)NCc1ccncc1 Show InChI InChI=1S/C24H22N4O3/c1-3-31-24(30)22-11-18-10-17(4-5-20(18)28-22)19-12-21(26-13-15(19)2)23(29)27-14-16-6-8-25-9-7-16/h4-13,28H,3,14H2,1-2H3,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50361634 (CHEMBL1939877 | US8785489, (4-{[({5-[2-(ethoxycarb...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccc(CC(O)=O)cc1 Show InChI InChI=1S/C25H24N4O5/c1-3-34-25(33)21-12-18-11-17(8-9-19(18)27-21)22-13-20(28-29(22)2)24(32)26-14-16-6-4-15(5-7-16)10-23(30)31/h4-9,11-13,27H,3,10,14H2,1-2H3,(H,26,32)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50361618 (CHEMBL1939876 | US8785489, 4-{[({5-[2-(ethoxycarbo...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H22N4O5/c1-3-33-24(32)20-11-17-10-16(8-9-18(17)26-20)21-12-19(27-28(21)2)22(29)25-13-14-4-6-15(7-5-14)23(30)31/h4-12,26H,3,13H2,1-2H3,(H,25,29)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP3 after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50361618 (CHEMBL1939876 | US8785489, 4-{[({5-[2-(ethoxycarbo...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H22N4O5/c1-3-33-24(32)20-11-17-10-16(8-9-18(17)26-20)21-12-19(27-28(21)2)22(29)25-13-14-4-6-15(7-5-14)23(30)31/h4-12,26H,3,13H2,1-2H3,(H,25,29)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP8 after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Matrilysin (Homo sapiens (Human))	BDBM50361618 (CHEMBL1939876 | US8785489, 4-{[({5-[2-(ethoxycarbo...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H22N4O5/c1-3-33-24(32)20-11-17-10-16(8-9-18(17)26-20)21-12-19(27-28(21)2)22(29)25-13-14-4-6-15(7-5-14)23(30)31/h4-12,26H,3,13H2,1-2H3,(H,25,29)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP7 after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50361635 (CHEMBL1939878 | US8785489, ethyl 5-{5-methyl-2-[(p...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(ncc1C)C(=O)NCc1ccncc1 Show InChI InChI=1S/C24H22N4O3/c1-3-31-24(30)22-11-18-10-17(4-5-20(18)28-22)19-12-21(26-13-15(19)2)23(29)27-14-16-6-8-25-9-7-16/h4-13,28H,3,14H2,1-2H3,(H,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP14 after 60 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50361634 (CHEMBL1939877 | US8785489, (4-{[({5-[2-(ethoxycarb...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccc(CC(O)=O)cc1 Show InChI InChI=1S/C25H24N4O5/c1-3-34-25(33)21-12-18-11-17(8-9-19(18)27-21)22-13-20(28-29(22)2)24(32)26-14-16-6-4-15(5-7-16)10-23(30)31/h4-9,11-13,27H,3,10,14H2,1-2H3,(H,26,32)(H,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP14 after 60 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50361618 (CHEMBL1939876 | US8785489, 4-{[({5-[2-(ethoxycarbo...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H22N4O5/c1-3-33-24(32)20-11-17-10-16(8-9-18(17)26-20)21-12-19(27-28(21)2)22(29)25-13-14-4-6-15(7-5-14)23(30)31/h4-12,26H,3,13H2,1-2H3,(H,25,29)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP1 after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Macrophage metalloelastase (Homo sapiens (Human))	BDBM50361618 (CHEMBL1939876 | US8785489, 4-{[({5-[2-(ethoxycarbo...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H22N4O5/c1-3-33-24(32)20-11-17-10-16(8-9-18(17)26-20)21-12-19(27-28(21)2)22(29)25-13-14-4-6-15(7-5-14)23(30)31/h4-12,26H,3,13H2,1-2H3,(H,25,29)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP12 after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50361633 (CHEMBL1939875 | US8785489, ethyl 5-(1-methyl-3-{[(...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccc(=O)[nH]c1 Show InChI InChI=1S/C22H21N5O4/c1-3-31-22(30)18-9-15-8-14(5-6-16(15)25-18)19-10-17(26-27(19)2)21(29)24-12-13-4-7-20(28)23-11-13/h4-11,25H,3,12H2,1-2H3,(H,23,28)(H,24,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50361630 (CHEMBL1939872) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cncn1C Show InChI InChI=1S/C15H15N3O2/c1-3-20-15(19)13-7-11-6-10(4-5-12(11)17-13)14-8-16-9-18(14)2/h4-9,17H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50361636 (CHEMBL1939879) Show SMILES Cn1nc(cc1-c1ccc2[nH]c(cc2c1)C(O)=O)C(=O)NCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C22H18N4O5/c1-26-19(14-6-7-16-15(8-14)9-18(24-16)22(30)31)10-17(25-26)20(27)23-11-12-2-4-13(5-3-12)21(28)29/h2-10,24H,11H2,1H3,(H,23,27)(H,28,29)(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human MMP13 expressed in Escherichia coli after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50361637 (CHEMBL1939880) Show SMILES Cn1nc(cc1-c1ccc2[nH]ccc2c1)C(=O)NCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C21H18N4O3/c1-25-19(16-6-7-17-15(10-16)8-9-22-17)11-18(24-25)20(26)23-12-13-2-4-14(5-3-13)21(27)28/h2-11,22H,12H2,1H3,(H,23,26)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human MMP13 expressed in Escherichia coli after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50361618 (CHEMBL1939876 | US8785489, 4-{[({5-[2-(ethoxycarbo...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H22N4O5/c1-3-33-24(32)20-11-17-10-16(8-9-18(17)26-20)21-12-19(27-28(21)2)22(29)25-13-14-4-6-15(7-5-14)23(30)31/h4-12,26H,3,13H2,1-2H3,(H,25,29)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant CYP3A4 using 7-benzyloxy-4-trifluoromethylcoumarin as substrate after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50361618 (CHEMBL1939876 | US8785489, 4-{[({5-[2-(ethoxycarbo...) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)NCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H22N4O5/c1-3-33-24(32)20-11-17-10-16(8-9-18(17)26-20)21-12-19(27-28(21)2)22(29)25-13-14-4-6-15(7-5-14)23(30)31/h4-12,26H,3,13H2,1-2H3,(H,25,29)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant CYP2C9 using 7-methoxy-4-trifluoromethylcoumarin as substrate after 45 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50361627 (CHEMBL1939869) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cccnc1 Show InChI InChI=1S/C16H14N2O2/c1-2-20-16(19)15-9-13-8-11(5-6-14(13)18-15)12-4-3-7-17-10-12/h3-10,18H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50361623 (CHEMBL1939865) Show SMILES CCOC(=O)c1cc2cc(NC(C)=O)ccc2[nH]1 Show InChI InChI=1S/C13H14N2O3/c1-3-18-13(17)12-7-9-6-10(14-8(2)16)4-5-11(9)15-12/h4-7,15H,3H2,1-2H3,(H,14,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human MMP13 expressed in Escherichia coli after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50361620 (CHEMBL1939862) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)C(N)=O Show InChI InChI=1S/C12H12N2O3/c1-2-17-12(16)10-6-8-5-7(11(13)15)3-4-9(8)14-10/h3-6,14H,2H2,1H3,(H2,13,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human MMP13 expressed in Escherichia coli after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair				3D Structure (crystal)
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50361631 (CHEMBL1939873) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)OC Show InChI InChI=1S/C17H17N3O4/c1-4-24-17(22)13-8-11-7-10(5-6-12(11)18-13)15-9-14(16(21)23-3)19-20(15)2/h5-9,18H,4H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP14 after 60 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50361627 (CHEMBL1939869) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cccnc1 Show InChI InChI=1S/C16H14N2O2/c1-2-20-16(19)15-9-13-8-11(5-6-14(13)18-15)12-4-3-7-17-10-12/h3-10,18H,2H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP14 after 60 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50361636 (CHEMBL1939879) Show SMILES Cn1nc(cc1-c1ccc2[nH]c(cc2c1)C(O)=O)C(=O)NCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C22H18N4O5/c1-26-19(14-6-7-16-15(8-14)9-18(24-16)22(30)31)10-17(25-26)20(27)23-11-12-2-4-13(5-3-12)21(28)29/h2-10,24H,11H2,1H3,(H,23,27)(H,28,29)(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of MMP13 after 30 mins by fluorimetry in the presence of 1.25% human serum albumin				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50361620 (CHEMBL1939862) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)C(N)=O Show InChI InChI=1S/C12H12N2O3/c1-2-17-12(16)10-6-8-5-7(11(13)15)3-4-9(8)14-10/h3-6,14H,2H2,1H3,(H2,13,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50361628 (CHEMBL1939870) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1ccncc1 Show InChI InChI=1S/C16H14N2O2/c1-2-20-16(19)15-10-13-9-12(3-4-14(13)18-15)11-5-7-17-8-6-11/h3-10,18H,2H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	8.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human MMP13 expressed in Escherichia coli after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50361631 (CHEMBL1939873) Show SMILES CCOC(=O)c1cc2cc(ccc2[nH]1)-c1cc(nn1C)C(=O)OC Show InChI InChI=1S/C17H17N3O4/c1-4-24-17(22)13-8-11-7-10(5-6-12(11)18-13)15-9-14(16(21)23-3)19-20(15)2/h5-9,18H,4H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50361619 (CHEMBL1939861) Show SMILES CCOC(=O)c1cc2cc(NS(C)(=O)=O)ccc2[nH]1 Show InChI InChI=1S/C12H14N2O4S/c1-3-18-12(15)11-7-8-6-9(14-19(2,16)17)4-5-10(8)13-11/h4-7,13-14H,3H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	9.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human MMP13 expressed in Escherichia coli after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50361619 (CHEMBL1939861) Show SMILES CCOC(=O)c1cc2cc(NS(C)(=O)=O)ccc2[nH]1 Show InChI InChI=1S/C12H14N2O4S/c1-3-18-12(15)11-7-8-6-9(14-19(2,16)17)4-5-10(8)13-11/h4-7,13-14H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 after 30 mins by fluorimetry				J Med Chem 54: 8174-87 (2011) Article DOI: 10.1021/jm201129m BindingDB Entry DOI: 10.7270/Q2C53M9C
					More data for this Ligand-Target Pair

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