BindingDB PrimarySearch

Found 20 hits Enz. Inhib. hit(s) with all data for entry = 50015461
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50156244 (Acetic acid 4-{1-[1-(4-methanesulfonyl-phenyl)-1-p...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description In vitro inhibition of ovine prostaglandin G/H synthase 2				J Med Chem 47: 6108-11 (2004) Article DOI: 10.1021/jm049523y BindingDB Entry DOI: 10.7270/Q2MG7P0Z
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description In vitro inhibition of ovine prostaglandin G/H synthase 2				J Med Chem 47: 6108-11 (2004) Article DOI: 10.1021/jm049523y BindingDB Entry DOI: 10.7270/Q2MG7P0Z
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50156244 (Acetic acid 4-{1-[1-(4-methanesulfonyl-phenyl)-1-p...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description In vitro inhibition of ovine prostaglandin G/H synthase 1				J Med Chem 47: 6108-11 (2004) Article DOI: 10.1021/jm049523y BindingDB Entry DOI: 10.7270/Q2MG7P0Z
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM22360 (2-(acetyloxy)benzoate \| 2-(acetyloxy)benzoic acid ...) Show SMILES CC(=O)Oc1ccccc1C(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description In vitro inhibition of ovine prostaglandin G/H synthase 1				J Med Chem 47: 6108-11 (2004) Article DOI: 10.1021/jm049523y BindingDB Entry DOI: 10.7270/Q2MG7P0Z
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50156242 (1-((Z)-1,2-Diphenyl-oct-1-enyl)-4-methanesulfonyl-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description In vitro inhibition of ovine prostaglandin G/H synthase 2				J Med Chem 47: 6108-11 (2004) Article DOI: 10.1021/jm049523y BindingDB Entry DOI: 10.7270/Q2MG7P0Z
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM22369 (4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description In vitro inhibition of ovine prostaglandin G/H synthase 2				J Med Chem 47: 6108-11 (2004) Article DOI: 10.1021/jm049523y BindingDB Entry DOI: 10.7270/Q2MG7P0Z
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50156239 (Acetic acid 4-{1-[1-(4-methanesulfonyl-phenyl)-1-p...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description In vitro inhibition of ovine prostaglandin G/H synthase 2				J Med Chem 47: 6108-11 (2004) Article DOI: 10.1021/jm049523y BindingDB Entry DOI: 10.7270/Q2MG7P0Z
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM22360 (2-(acetyloxy)benzoate \| 2-(acetyloxy)benzoic acid ...) Show SMILES CC(=O)Oc1ccccc1C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description In vitro inhibition of ovine prostaglandin G/H synthase 2				J Med Chem 47: 6108-11 (2004) Article DOI: 10.1021/jm049523y BindingDB Entry DOI: 10.7270/Q2MG7P0Z
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50156241 (1-((Z)-1,2-Diphenyl-pent-1-enyl)-4-methanesulfonyl...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description In vitro inhibition of ovine prostaglandin G/H synthase 2				J Med Chem 47: 6108-11 (2004) Article DOI: 10.1021/jm049523y BindingDB Entry DOI: 10.7270/Q2MG7P0Z
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50156243 (1-((Z)-1,2-Diphenyl-dec-1-enyl)-4-methanesulfonyl-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description In vitro inhibition of ovine prostaglandin G/H synthase 2				J Med Chem 47: 6108-11 (2004) Article DOI: 10.1021/jm049523y BindingDB Entry DOI: 10.7270/Q2MG7P0Z
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50156240 (1-((Z)-1,2-Diphenyl-but-1-enyl)-4-methanesulfonyl-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description In vitro inhibition of ovine prostaglandin G/H synthase 2				J Med Chem 47: 6108-11 (2004) Article DOI: 10.1021/jm049523y BindingDB Entry DOI: 10.7270/Q2MG7P0Z
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50156245 (1-((Z)-1,2-Diphenyl-hex-1-enyl)-4-methanesulfonyl-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description In vitro inhibition of ovine prostaglandin G/H synthase 2				J Med Chem 47: 6108-11 (2004) Article DOI: 10.1021/jm049523y BindingDB Entry DOI: 10.7270/Q2MG7P0Z
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50156245 (1-((Z)-1,2-Diphenyl-hex-1-enyl)-4-methanesulfonyl-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description In vitro inhibition of ovine prostaglandin G/H synthase 1				J Med Chem 47: 6108-11 (2004) Article DOI: 10.1021/jm049523y BindingDB Entry DOI: 10.7270/Q2MG7P0Z
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description In vitro inhibition of ovine prostaglandin G/H synthase 1				J Med Chem 47: 6108-11 (2004) Article DOI: 10.1021/jm049523y BindingDB Entry DOI: 10.7270/Q2MG7P0Z
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50156240 (1-((Z)-1,2-Diphenyl-but-1-enyl)-4-methanesulfonyl-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description In vitro inhibition of ovine prostaglandin G/H synthase 1				J Med Chem 47: 6108-11 (2004) Article DOI: 10.1021/jm049523y BindingDB Entry DOI: 10.7270/Q2MG7P0Z
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50156239 (Acetic acid 4-{1-[1-(4-methanesulfonyl-phenyl)-1-p...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description In vitro inhibition of ovine prostaglandin G/H synthase 1				J Med Chem 47: 6108-11 (2004) Article DOI: 10.1021/jm049523y BindingDB Entry DOI: 10.7270/Q2MG7P0Z
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50156241 (1-((Z)-1,2-Diphenyl-pent-1-enyl)-4-methanesulfonyl...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description In vitro inhibition of ovine prostaglandin G/H synthase 1				J Med Chem 47: 6108-11 (2004) Article DOI: 10.1021/jm049523y BindingDB Entry DOI: 10.7270/Q2MG7P0Z
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50156242 (1-((Z)-1,2-Diphenyl-oct-1-enyl)-4-methanesulfonyl-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description In vitro inhibition of ovine prostaglandin G/H synthase 1				J Med Chem 47: 6108-11 (2004) Article DOI: 10.1021/jm049523y BindingDB Entry DOI: 10.7270/Q2MG7P0Z
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50156243 (1-((Z)-1,2-Diphenyl-dec-1-enyl)-4-methanesulfonyl-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description In vitro inhibition of ovine prostaglandin G/H synthase 1				J Med Chem 47: 6108-11 (2004) Article DOI: 10.1021/jm049523y BindingDB Entry DOI: 10.7270/Q2MG7P0Z
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM22369 (4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description In vitro inhibition of ovine prostaglandin G/H synthase 1				J Med Chem 47: 6108-11 (2004) Article DOI: 10.1021/jm049523y BindingDB Entry DOI: 10.7270/Q2MG7P0Z
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair