Found 22 hits Enz. Inhib. hit(s) with all data for entry = 50020751 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50217120
(1,2-dihydro-7-methoxy-3-(2,3,4-trimethoxyphenyl)-n...)Show SMILES COc1ccc2C=C(CCc2c1)c1ccc(OC)c(OC)c1OC |c:6| Show InChI InChI=1S/C20H22O4/c1-21-16-8-7-13-11-15(6-5-14(13)12-16)17-9-10-18(22-2)20(24-4)19(17)23-3/h7-12H,5-6H2,1-4H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vienna
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 by measuring PGE2 |
Bioorg Med Chem 15: 6109-18 (2007)
Article DOI: 10.1016/j.bmc.2007.06.030 BindingDB Entry DOI: 10.7270/Q2G160JR |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50217117
(2-(2,3,4-trimethoxyphenyl)-1H-indene | CHEMBL22856...)Show InChI InChI=1S/C18H18O3/c1-19-16-9-8-15(17(20-2)18(16)21-3)14-10-12-6-4-5-7-13(12)11-14/h4-10H,11H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vienna
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 by measuring PGE2 |
Bioorg Med Chem 15: 6109-18 (2007)
Article DOI: 10.1016/j.bmc.2007.06.030 BindingDB Entry DOI: 10.7270/Q2G160JR |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50217121
(1,2-dihydro-3-(3,4-dimethoxyphenyl)-7-methoxynapht...)Show InChI InChI=1S/C19H20O3/c1-20-17-8-6-14-10-13(4-5-15(14)11-17)16-7-9-18(21-2)19(12-16)22-3/h6-12H,4-5H2,1-3H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vienna
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 by measuring PGE2 |
Bioorg Med Chem 15: 6109-18 (2007)
Article DOI: 10.1016/j.bmc.2007.06.030 BindingDB Entry DOI: 10.7270/Q2G160JR |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM11639
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PDB Article PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vienna
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 by measuring PGE2 |
Bioorg Med Chem 15: 6109-18 (2007)
Article DOI: 10.1016/j.bmc.2007.06.030 BindingDB Entry DOI: 10.7270/Q2G160JR |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50217121
(1,2-dihydro-3-(3,4-dimethoxyphenyl)-7-methoxynapht...)Show InChI InChI=1S/C19H20O3/c1-20-17-8-6-14-10-13(4-5-15(14)11-17)16-7-9-18(21-2)19(12-16)22-3/h6-12H,4-5H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vienna
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 by measuring PGE2 |
Bioorg Med Chem 15: 6109-18 (2007)
Article DOI: 10.1016/j.bmc.2007.06.030 BindingDB Entry DOI: 10.7270/Q2G160JR |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50217115
(2-(2-methoxyphenyl)-1H-indene | CHEMBL376583)Show InChI InChI=1S/C16H14O/c1-17-16-9-5-4-8-15(16)14-10-12-6-2-3-7-13(12)11-14/h2-10H,11H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vienna
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 by measuring PGE2 |
Bioorg Med Chem 15: 6109-18 (2007)
Article DOI: 10.1016/j.bmc.2007.06.030 BindingDB Entry DOI: 10.7270/Q2G160JR |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50217119
(1,2-dihydro-3-(2,3,4-trimethoxyphenyl)naphthalene ...)Show InChI InChI=1S/C19H20O3/c1-20-17-11-10-16(18(21-2)19(17)22-3)15-9-8-13-6-4-5-7-14(13)12-15/h4-7,10-12H,8-9H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vienna
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 by measuring PGE2 |
Bioorg Med Chem 15: 6109-18 (2007)
Article DOI: 10.1016/j.bmc.2007.06.030 BindingDB Entry DOI: 10.7270/Q2G160JR |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM23926
((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)Show InChI InChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+ | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 535 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vienna
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 by measuring PGE2 |
Bioorg Med Chem 15: 6109-18 (2007)
Article DOI: 10.1016/j.bmc.2007.06.030 BindingDB Entry DOI: 10.7270/Q2G160JR |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50217119
(1,2-dihydro-3-(2,3,4-trimethoxyphenyl)naphthalene ...)Show InChI InChI=1S/C19H20O3/c1-20-17-11-10-16(18(21-2)19(17)22-3)15-9-8-13-6-4-5-7-14(13)12-15/h4-7,10-12H,8-9H2,1-3H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 660 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vienna
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 by measuring PGE2 |
Bioorg Med Chem 15: 6109-18 (2007)
Article DOI: 10.1016/j.bmc.2007.06.030 BindingDB Entry DOI: 10.7270/Q2G160JR |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM23926
((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)Show InChI InChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 996 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vienna
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 by measuring PGE2 |
Bioorg Med Chem 15: 6109-18 (2007)
Article DOI: 10.1016/j.bmc.2007.06.030 BindingDB Entry DOI: 10.7270/Q2G160JR |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50217117
(2-(2,3,4-trimethoxyphenyl)-1H-indene | CHEMBL22856...)Show InChI InChI=1S/C18H18O3/c1-19-16-9-8-15(17(20-2)18(16)21-3)14-10-12-6-4-5-7-13(12)11-14/h4-10H,11H2,1-3H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vienna
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 by measuring PGE2 |
Bioorg Med Chem 15: 6109-18 (2007)
Article DOI: 10.1016/j.bmc.2007.06.030 BindingDB Entry DOI: 10.7270/Q2G160JR |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50217118
(5-(2-1H-indenyl)-1,3-benzodioxole | CHEMBL229139)Show InChI InChI=1S/C16H12O2/c1-2-4-12-8-14(7-11(12)3-1)13-5-6-15-16(9-13)18-10-17-15/h1-7,9H,8,10H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.28E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vienna
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 by measuring PGE2 |
Bioorg Med Chem 15: 6109-18 (2007)
Article DOI: 10.1016/j.bmc.2007.06.030 BindingDB Entry DOI: 10.7270/Q2G160JR |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM11639
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vienna
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 by measuring PGE2 |
Bioorg Med Chem 15: 6109-18 (2007)
Article DOI: 10.1016/j.bmc.2007.06.030 BindingDB Entry DOI: 10.7270/Q2G160JR |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50217116
(1,2-dihydro-3-(3,4-dimethoxyphenyl)naphthalene | C...)Show InChI InChI=1S/C18H18O2/c1-19-17-10-9-16(12-18(17)20-2)15-8-7-13-5-3-4-6-14(13)11-15/h3-6,9-12H,7-8H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.11E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vienna
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 by measuring PGE2 |
Bioorg Med Chem 15: 6109-18 (2007)
Article DOI: 10.1016/j.bmc.2007.06.030 BindingDB Entry DOI: 10.7270/Q2G160JR |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50217115
(2-(2-methoxyphenyl)-1H-indene | CHEMBL376583)Show InChI InChI=1S/C16H14O/c1-17-16-9-5-4-8-15(16)14-10-12-6-2-3-7-13(12)11-14/h2-10H,11H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 6.23E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vienna
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 by measuring PGE2 |
Bioorg Med Chem 15: 6109-18 (2007)
Article DOI: 10.1016/j.bmc.2007.06.030 BindingDB Entry DOI: 10.7270/Q2G160JR |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM22360
(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)Show InChI InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 9.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vienna
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 by measuring PGE2 |
Bioorg Med Chem 15: 6109-18 (2007)
Article DOI: 10.1016/j.bmc.2007.06.030 BindingDB Entry DOI: 10.7270/Q2G160JR |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50217122
(5-(1,2-dihydro-3-naphthalenyl)-1,3-benzodioxole | ...)Show InChI InChI=1S/C17H14O2/c1-2-4-13-9-14(6-5-12(13)3-1)15-7-8-16-17(10-15)19-11-18-16/h1-4,7-10H,5-6,11H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vienna
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 by measuring PGE2 |
Bioorg Med Chem 15: 6109-18 (2007)
Article DOI: 10.1016/j.bmc.2007.06.030 BindingDB Entry DOI: 10.7270/Q2G160JR |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50217116
(1,2-dihydro-3-(3,4-dimethoxyphenyl)naphthalene | C...)Show InChI InChI=1S/C18H18O2/c1-19-17-10-9-16(12-18(17)20-2)15-8-7-13-5-3-4-6-14(13)11-15/h3-6,9-12H,7-8H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vienna
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 by measuring PGE2 |
Bioorg Med Chem 15: 6109-18 (2007)
Article DOI: 10.1016/j.bmc.2007.06.030 BindingDB Entry DOI: 10.7270/Q2G160JR |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50217118
(5-(2-1H-indenyl)-1,3-benzodioxole | CHEMBL229139)Show InChI InChI=1S/C16H12O2/c1-2-4-12-8-14(7-11(12)3-1)13-5-6-15-16(9-13)18-10-17-15/h1-7,9H,8,10H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vienna
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 by measuring PGE2 |
Bioorg Med Chem 15: 6109-18 (2007)
Article DOI: 10.1016/j.bmc.2007.06.030 BindingDB Entry DOI: 10.7270/Q2G160JR |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50217122
(5-(1,2-dihydro-3-naphthalenyl)-1,3-benzodioxole | ...)Show InChI InChI=1S/C17H14O2/c1-2-4-13-9-14(6-5-12(13)3-1)15-7-8-16-17(10-15)19-11-18-16/h1-4,7-10H,5-6,11H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vienna
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 by measuring PGE2 |
Bioorg Med Chem 15: 6109-18 (2007)
Article DOI: 10.1016/j.bmc.2007.06.030 BindingDB Entry DOI: 10.7270/Q2G160JR |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM22360
(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)Show InChI InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank Article PubMed
| n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vienna
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 by measuring PGE2 |
Bioorg Med Chem 15: 6109-18 (2007)
Article DOI: 10.1016/j.bmc.2007.06.030 BindingDB Entry DOI: 10.7270/Q2G160JR |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50217120
(1,2-dihydro-7-methoxy-3-(2,3,4-trimethoxyphenyl)-n...)Show SMILES COc1ccc2C=C(CCc2c1)c1ccc(OC)c(OC)c1OC |c:6| Show InChI InChI=1S/C20H22O4/c1-21-16-8-7-13-11-15(6-5-14(13)12-16)17-9-10-18(22-2)20(24-4)19(17)23-3/h7-12H,5-6H2,1-4H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vienna
Curated by ChEMBL
| Assay Description Inhibition of human recombinant COX2 by measuring PGE2 |
Bioorg Med Chem 15: 6109-18 (2007)
Article DOI: 10.1016/j.bmc.2007.06.030 BindingDB Entry DOI: 10.7270/Q2G160JR |
More data for this Ligand-Target Pair | |