BindingDB PrimarySearch

Found 14 hits Enz. Inhib. hit(s) with all data for entry = 50021807
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM19264 ((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMPDH 2				J Med Chem 50: 6685-91 (2007) Article DOI: 10.1021/jm070864w BindingDB Entry DOI: 10.7270/Q2ZK5GCS
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50228085 (CHEMBL238461 \| N-hydroxy-6-(4-hydroxy-6-methoxy-7-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMPDH 2				J Med Chem 50: 6685-91 (2007) Article DOI: 10.1021/jm070864w BindingDB Entry DOI: 10.7270/Q2ZK5GCS
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human))	BDBM19264 ((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMPDH 1				J Med Chem 50: 6685-91 (2007) Article DOI: 10.1021/jm070864w BindingDB Entry DOI: 10.7270/Q2ZK5GCS
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human))	BDBM50228085 (CHEMBL238461 \| N-hydroxy-6-(4-hydroxy-6-methoxy-7-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMPDH 1				J Med Chem 50: 6685-91 (2007) Article DOI: 10.1021/jm070864w BindingDB Entry DOI: 10.7270/Q2ZK5GCS
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human))	BDBM19253 (CHEMBL394276 \| NSC 358285 \| Tiazofurin Adenine Din...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMPDH 1				J Med Chem 50: 6685-91 (2007) Article DOI: 10.1021/jm070864w BindingDB Entry DOI: 10.7270/Q2ZK5GCS
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM19253 (CHEMBL394276 \| NSC 358285 \| Tiazofurin Adenine Din...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMPDH 2				J Med Chem 50: 6685-91 (2007) Article DOI: 10.1021/jm070864w BindingDB Entry DOI: 10.7270/Q2ZK5GCS
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human))	BDBM50228088 (CHEMBL392178 \| N-hydroxy-7-(4-hydroxy-6-methoxy-7-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMPDH 1				J Med Chem 50: 6685-91 (2007) Article DOI: 10.1021/jm070864w BindingDB Entry DOI: 10.7270/Q2ZK5GCS
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50228083 (CHEMBL238905 \| N-hydroxy-6-(4-hydroxy-6-methoxy-7-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMPDH 2				J Med Chem 50: 6685-91 (2007) Article DOI: 10.1021/jm070864w BindingDB Entry DOI: 10.7270/Q2ZK5GCS
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50228082 (CHEMBL239105 \| N-(2-aminophenyl)-6-(4-hydroxy-6-me...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	650	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMPDH 2				J Med Chem 50: 6685-91 (2007) Article DOI: 10.1021/jm070864w BindingDB Entry DOI: 10.7270/Q2ZK5GCS
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50228088 (CHEMBL392178 \| N-hydroxy-7-(4-hydroxy-6-methoxy-7-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMPDH 2				J Med Chem 50: 6685-91 (2007) Article DOI: 10.1021/jm070864w BindingDB Entry DOI: 10.7270/Q2ZK5GCS
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50228086 (CHEMBL429090 \| N1-hydroxy-N8-(3-methoxy-4-(oxazol-...) Show SMILES COc1cc(NC(=O)CCCCCCC(=O)NO)ccc1-c1cnco1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMPDH 2				J Med Chem 50: 6685-91 (2007) Article DOI: 10.1021/jm070864w BindingDB Entry DOI: 10.7270/Q2ZK5GCS
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human))	BDBM50228083 (CHEMBL238905 \| N-hydroxy-6-(4-hydroxy-6-methoxy-7-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMPDH 1				J Med Chem 50: 6685-91 (2007) Article DOI: 10.1021/jm070864w BindingDB Entry DOI: 10.7270/Q2ZK5GCS
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human))	BDBM50228082 (CHEMBL239105 \| N-(2-aminophenyl)-6-(4-hydroxy-6-me...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.83E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMPDH 1				J Med Chem 50: 6685-91 (2007) Article DOI: 10.1021/jm070864w BindingDB Entry DOI: 10.7270/Q2ZK5GCS
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 1 (Homo sapiens (Human))	BDBM50228086 (CHEMBL429090 \| N1-hydroxy-N8-(3-methoxy-4-(oxazol-...) Show SMILES COc1cc(NC(=O)CCCCCCC(=O)NO)ccc1-c1cnco1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human IMPDH 1				J Med Chem 50: 6685-91 (2007) Article DOI: 10.1021/jm070864w BindingDB Entry DOI: 10.7270/Q2ZK5GCS
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair