Compile Data Set for Download or QSAR

Found 24 hits Enz. Inhib. hit(s) with all data for entry = 50029303   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Sigma opioid receptor type 1 in guinea pig brain homogenate with 0.5 nM [3H]-(+)-PENT				Bioorg Med Chem Lett 4: 2185-2188 (1994) Article DOI: 10.1016/S0960-894X(00)80068-2 BindingDB Entry DOI: 10.7270/Q22N5266
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50035131 ((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...) Show SMILES [#6]-[#6@@H]1-[#6@@H]-2-[#6]-c3ccc(-[#8])cc3[C@@]1([#6])[#6]-[#6]-[#7]-2-[#6]\[#6]=[#6](/[#6])-[#6] |r,TLB:16:15:10.4.3:1| Show InChI InChI=1S/C19H27NO/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19/h5-7,12,14,18,21H,8-11H2,1-4H3/t14-,18+,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Sigma opioid receptor type 1 in guinea pig brain homogenate with 0.5 nM [3H]-(+)-PENT				Bioorg Med Chem Lett 4: 2185-2188 (1994) Article DOI: 10.1016/S0960-894X(00)80068-2 BindingDB Entry DOI: 10.7270/Q22N5266
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50283109 (5,5-Diphenyl-3-[6-(4-phenyl-piperidin-1-yl)-hexyl]...) Show SMILES O=C1NC(C(=O)N1CCCCCCN1CCC(CC1)c1ccccc1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C32H37N3O2/c36-30-32(28-16-8-4-9-17-28,29-18-10-5-11-19-29)33-31(37)35(30)23-13-2-1-12-22-34-24-20-27(21-25-34)26-14-6-3-7-15-26/h3-11,14-19,27H,1-2,12-13,20-25H2,(H,33,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Sigma opioid receptor type 1 in guinea pig brain homogenate with 0.5 nM [3H]-(+)-PENT				Bioorg Med Chem Lett 4: 2185-2188 (1994) Article DOI: 10.1016/S0960-894X(00)80068-2 BindingDB Entry DOI: 10.7270/Q22N5266
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50283109 (5,5-Diphenyl-3-[6-(4-phenyl-piperidin-1-yl)-hexyl]...) Show SMILES O=C1NC(C(=O)N1CCCCCCN1CCC(CC1)c1ccccc1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C32H37N3O2/c36-30-32(28-16-8-4-9-17-28,29-18-10-5-11-19-29)33-31(37)35(30)23-13-2-1-12-22-34-24-20-27(21-25-34)26-14-6-3-7-15-26/h3-11,14-19,27H,1-2,12-13,20-25H2,(H,33,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTG				Bioorg Med Chem Lett 4: 2185-2188 (1994) Article DOI: 10.1016/S0960-894X(00)80068-2 BindingDB Entry DOI: 10.7270/Q22N5266
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTG				Bioorg Med Chem Lett 4: 2185-2188 (1994) Article DOI: 10.1016/S0960-894X(00)80068-2 BindingDB Entry DOI: 10.7270/Q22N5266
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50283108 (5,5-Diphenyl-3-[4-(4-phenyl-piperidin-1-yl)-butyl]...) Show SMILES O=C1NC(C(=O)N1CCCCN1CCC(CC1)c1ccccc1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C30H33N3O2/c34-28-30(26-14-6-2-7-15-26,27-16-8-3-9-17-27)31-29(35)33(28)21-11-10-20-32-22-18-25(19-23-32)24-12-4-1-5-13-24/h1-9,12-17,25H,10-11,18-23H2,(H,31,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	8.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTG				Bioorg Med Chem Lett 4: 2185-2188 (1994) Article DOI: 10.1016/S0960-894X(00)80068-2 BindingDB Entry DOI: 10.7270/Q22N5266
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50283108 (5,5-Diphenyl-3-[4-(4-phenyl-piperidin-1-yl)-butyl]...) Show SMILES O=C1NC(C(=O)N1CCCCN1CCC(CC1)c1ccccc1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C30H33N3O2/c34-28-30(26-14-6-2-7-15-26,27-16-8-3-9-17-27)31-29(35)33(28)21-11-10-20-32-22-18-25(19-23-32)24-12-4-1-5-13-24/h1-9,12-17,25H,10-11,18-23H2,(H,31,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Sigma opioid receptor type 1 in guinea pig brain homogenate with 0.5 nM [3H]-(+)-PENT				Bioorg Med Chem Lett 4: 2185-2188 (1994) Article DOI: 10.1016/S0960-894X(00)80068-2 BindingDB Entry DOI: 10.7270/Q22N5266
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50283107 (5,5-Diphenyl-3-[6-(4-phenyl-piperazin-1-yl)-hexyl]...) Show SMILES O=C1NC(C(=O)N1CCCCCCN1CCN(CC1)c1ccccc1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H36N4O2/c36-29-31(26-14-6-3-7-15-26,27-16-8-4-9-17-27)32-30(37)35(29)21-13-2-1-12-20-33-22-24-34(25-23-33)28-18-10-5-11-19-28/h3-11,14-19H,1-2,12-13,20-25H2,(H,32,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTG				Bioorg Med Chem Lett 4: 2185-2188 (1994) Article DOI: 10.1016/S0960-894X(00)80068-2 BindingDB Entry DOI: 10.7270/Q22N5266
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50283107 (5,5-Diphenyl-3-[6-(4-phenyl-piperazin-1-yl)-hexyl]...) Show SMILES O=C1NC(C(=O)N1CCCCCCN1CCN(CC1)c1ccccc1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H36N4O2/c36-29-31(26-14-6-3-7-15-26,27-16-8-4-9-17-27)32-30(37)35(29)21-13-2-1-12-20-33-22-24-34(25-23-33)28-18-10-5-11-19-28/h3-11,14-19H,1-2,12-13,20-25H2,(H,32,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Sigma opioid receptor type 1 in guinea pig brain homogenate with 0.5 nM [3H]-(+)-PENT				Bioorg Med Chem Lett 4: 2185-2188 (1994) Article DOI: 10.1016/S0960-894X(00)80068-2 BindingDB Entry DOI: 10.7270/Q22N5266
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50283112 (5,5-Diphenyl-3-[2-(4-phenyl-piperidin-1-yl)-ethyl]...) Show SMILES O=C1NC(C(=O)N1CCN1CCC(CC1)c1ccccc1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H29N3O2/c32-26-28(24-12-6-2-7-13-24,25-14-8-3-9-15-25)29-27(33)31(26)21-20-30-18-16-23(17-19-30)22-10-4-1-5-11-22/h1-15,23H,16-21H2,(H,29,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Sigma opioid receptor type 1 in guinea pig brain homogenate with 0.5 nM [3H]-(+)-PENT				Bioorg Med Chem Lett 4: 2185-2188 (1994) Article DOI: 10.1016/S0960-894X(00)80068-2 BindingDB Entry DOI: 10.7270/Q22N5266
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50283114 (5,5-Diphenyl-3-[5-(4-phenyl-piperazin-1-yl)-pentyl...) Show SMILES O=C1NC(C(=O)N1CCCCCN1CCN(CC1)c1ccccc1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C30H34N4O2/c35-28-30(25-13-5-1-6-14-25,26-15-7-2-8-16-26)31-29(36)34(28)20-12-4-11-19-32-21-23-33(24-22-32)27-17-9-3-10-18-27/h1-3,5-10,13-18H,4,11-12,19-24H2,(H,31,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTG				Bioorg Med Chem Lett 4: 2185-2188 (1994) Article DOI: 10.1016/S0960-894X(00)80068-2 BindingDB Entry DOI: 10.7270/Q22N5266
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50283114 (5,5-Diphenyl-3-[5-(4-phenyl-piperazin-1-yl)-pentyl...) Show SMILES O=C1NC(C(=O)N1CCCCCN1CCN(CC1)c1ccccc1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C30H34N4O2/c35-28-30(25-13-5-1-6-14-25,26-15-7-2-8-16-26)31-29(36)34(28)20-12-4-11-19-32-21-23-33(24-22-32)27-17-9-3-10-18-27/h1-3,5-10,13-18H,4,11-12,19-24H2,(H,31,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTG				Bioorg Med Chem Lett 4: 2185-2188 (1994) Article DOI: 10.1016/S0960-894X(00)80068-2 BindingDB Entry DOI: 10.7270/Q22N5266
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50283111 (5,5-Diphenyl-3-[3-(4-phenyl-piperidin-1-yl)-propyl...) Show SMILES O=C1NC(C(=O)N1CCCN1CCC(CC1)c1ccccc1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H31N3O2/c33-27-29(25-13-6-2-7-14-25,26-15-8-3-9-16-26)30-28(34)32(27)20-10-19-31-21-17-24(18-22-31)23-11-4-1-5-12-23/h1-9,11-16,24H,10,17-22H2,(H,30,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Sigma opioid receptor type 1 in guinea pig brain homogenate with 0.5 nM [3H]-(+)-PENT				Bioorg Med Chem Lett 4: 2185-2188 (1994) Article DOI: 10.1016/S0960-894X(00)80068-2 BindingDB Entry DOI: 10.7270/Q22N5266
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50283111 (5,5-Diphenyl-3-[3-(4-phenyl-piperidin-1-yl)-propyl...) Show SMILES O=C1NC(C(=O)N1CCCN1CCC(CC1)c1ccccc1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H31N3O2/c33-27-29(25-13-6-2-7-14-25,26-15-8-3-9-16-26)30-28(34)32(27)20-10-19-31-21-17-24(18-22-31)23-11-4-1-5-12-23/h1-9,11-16,24H,10,17-22H2,(H,30,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTG				Bioorg Med Chem Lett 4: 2185-2188 (1994) Article DOI: 10.1016/S0960-894X(00)80068-2 BindingDB Entry DOI: 10.7270/Q22N5266
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50283112 (5,5-Diphenyl-3-[2-(4-phenyl-piperidin-1-yl)-ethyl]...) Show SMILES O=C1NC(C(=O)N1CCN1CCC(CC1)c1ccccc1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H29N3O2/c32-26-28(24-12-6-2-7-13-24,25-14-8-3-9-15-25)29-27(33)31(26)21-20-30-18-16-23(17-19-30)22-10-4-1-5-11-22/h1-15,23H,16-21H2,(H,29,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTG				Bioorg Med Chem Lett 4: 2185-2188 (1994) Article DOI: 10.1016/S0960-894X(00)80068-2 BindingDB Entry DOI: 10.7270/Q22N5266
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50283113 (5,5-Diphenyl-3-[4-(4-phenyl-piperazin-1-yl)-butyl]...) Show SMILES O=C1NC(C(=O)N1CCCCN1CCN(CC1)c1ccccc1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H32N4O2/c34-27-29(24-12-4-1-5-13-24,25-14-6-2-7-15-25)30-28(35)33(27)19-11-10-18-31-20-22-32(23-21-31)26-16-8-3-9-17-26/h1-9,12-17H,10-11,18-23H2,(H,30,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTG				Bioorg Med Chem Lett 4: 2185-2188 (1994) Article DOI: 10.1016/S0960-894X(00)80068-2 BindingDB Entry DOI: 10.7270/Q22N5266
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM81982 (CAS_97-39-2 | DITOLYLGUANIDINE | DTG | Di-o-tolylg...) Show SMILES Cc1ccccc1NC(N)=Nc1ccccc1C |w:10.11| Show InChI InChI=1S/C15H17N3/c1-11-7-3-5-9-13(11)17-15(16)18-14-10-6-4-8-12(14)2/h3-10H,1-2H3,(H3,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTG				Bioorg Med Chem Lett 4: 2185-2188 (1994) Article DOI: 10.1016/S0960-894X(00)80068-2 BindingDB Entry DOI: 10.7270/Q22N5266
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM81982 (CAS_97-39-2 | DITOLYLGUANIDINE | DTG | Di-o-tolylg...) Show SMILES Cc1ccccc1NC(N)=Nc1ccccc1C |w:10.11| Show InChI InChI=1S/C15H17N3/c1-11-7-3-5-9-13(11)17-15(16)18-14-10-6-4-8-12(14)2/h3-10H,1-2H3,(H3,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article	107	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Sigma opioid receptor type 1 in guinea pig brain homogenate with 0.5 nM [3H]-(+)-PENT				Bioorg Med Chem Lett 4: 2185-2188 (1994) Article DOI: 10.1016/S0960-894X(00)80068-2 BindingDB Entry DOI: 10.7270/Q22N5266
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50002238 ((R)1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-...) Show SMILES OC(CCCN1CCN(CC1)c1ncc(F)cn1)c1ccc(F)cc1 Show InChI InChI=1S/C18H22F2N4O/c19-15-5-3-14(4-6-15)17(25)2-1-7-23-8-10-24(11-9-23)18-21-12-16(20)13-22-18/h3-6,12-13,17,25H,1-2,7-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	164	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTG				Bioorg Med Chem Lett 4: 2185-2188 (1994) Article DOI: 10.1016/S0960-894X(00)80068-2 BindingDB Entry DOI: 10.7270/Q22N5266
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50002238 ((R)1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-...) Show SMILES OC(CCCN1CCN(CC1)c1ncc(F)cn1)c1ccc(F)cc1 Show InChI InChI=1S/C18H22F2N4O/c19-15-5-3-14(4-6-15)17(25)2-1-7-23-8-10-24(11-9-23)18-21-12-16(20)13-22-18/h3-6,12-13,17,25H,1-2,7-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	265	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Sigma opioid receptor type 1 in guinea pig brain homogenate with 0.5 nM [3H]-(+)-PENT				Bioorg Med Chem Lett 4: 2185-2188 (1994) Article DOI: 10.1016/S0960-894X(00)80068-2 BindingDB Entry DOI: 10.7270/Q22N5266
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50283113 (5,5-Diphenyl-3-[4-(4-phenyl-piperazin-1-yl)-butyl]...) Show SMILES O=C1NC(C(=O)N1CCCCN1CCN(CC1)c1ccccc1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H32N4O2/c34-27-29(24-12-4-1-5-13-24,25-14-6-2-7-15-25)30-28(35)33(27)19-11-10-18-31-20-22-32(23-21-31)26-16-8-3-9-17-26/h1-9,12-17H,10-11,18-23H2,(H,30,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	328	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Sigma opioid receptor type 1 in guinea pig brain homogenate with 0.5 nM [3H]-(+)-PENT				Bioorg Med Chem Lett 4: 2185-2188 (1994) Article DOI: 10.1016/S0960-894X(00)80068-2 BindingDB Entry DOI: 10.7270/Q22N5266
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50035131 ((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...) Show SMILES [#6]-[#6@@H]1-[#6@@H]-2-[#6]-c3ccc(-[#8])cc3[C@@]1([#6])[#6]-[#6]-[#7]-2-[#6]\[#6]=[#6](/[#6])-[#6] |r,TLB:16:15:10.4.3:1| Show InChI InChI=1S/C19H27NO/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19/h5-7,12,14,18,21H,8-11H2,1-4H3/t14-,18+,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article	562	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Sigma opioid receptor type 1 in guinea pig brain homogenate with 0.5 nM [3H]-(+)-PENT				Bioorg Med Chem Lett 4: 2185-2188 (1994) Article DOI: 10.1016/S0960-894X(00)80068-2 BindingDB Entry DOI: 10.7270/Q22N5266
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50283110 (5,5-Diphenyl-3-[2-(4-phenyl-piperazin-1-yl)-ethyl]...) Show SMILES O=C1NC(C(=O)N1CCN1CCN(CC1)c1ccccc1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H28N4O2/c32-25-27(22-10-4-1-5-11-22,23-12-6-2-7-13-23)28-26(33)31(25)21-18-29-16-19-30(20-17-29)24-14-8-3-9-15-24/h1-15H,16-21H2,(H,28,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	664	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Sigma opioid receptor type 1 in guinea pig brain homogenate with 0.5 nM [3H]-(+)-PENT				Bioorg Med Chem Lett 4: 2185-2188 (1994) Article DOI: 10.1016/S0960-894X(00)80068-2 BindingDB Entry DOI: 10.7270/Q22N5266
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50283110 (5,5-Diphenyl-3-[2-(4-phenyl-piperazin-1-yl)-ethyl]...) Show SMILES O=C1NC(C(=O)N1CCN1CCN(CC1)c1ccccc1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H28N4O2/c32-25-27(22-10-4-1-5-11-22,23-12-6-2-7-13-23)28-26(33)31(25)21-18-29-16-19-30(20-17-29)24-14-8-3-9-15-24/h1-15H,16-21H2,(H,28,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	842	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Sigma opioid receptor type 2 in guinea pig brain homogenate with 4 nM [3H]-(+)-DTG				Bioorg Med Chem Lett 4: 2185-2188 (1994) Article DOI: 10.1016/S0960-894X(00)80068-2 BindingDB Entry DOI: 10.7270/Q22N5266
					More data for this Ligand-Target Pair