Compile Data Set for Download or QSAR

Found 22 hits Enz. Inhib. hit(s) with all data for entry = 50030735   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50300681 (2-(4-methoxyphenyl)-5-methyl-2H-pyrazolo[4,3-d]pyr...) Show SMILES COc1ccc(cc1)-n1cc2nc(C)[nH]c(=O)c2n1 Show InChI InChI=1S/C13H12N4O2/c1-8-14-11-7-17(16-12(11)13(18)15-8)9-3-5-10(19-2)6-4-9/h3-7H,1-2H3,(H,14,15,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cells after 120 mins by scintillation counting				J Med Chem 52: 7640-52 (2009) Article DOI: 10.1021/jm900718w BindingDB Entry DOI: 10.7270/Q26T0MP5
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM21190 (4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...) Show SMILES Nc1nc(NCCc2ccc(O)cc2)nc2nc(nn12)-c1ccco1 Show InChI InChI=1S/C16H15N7O2/c17-14-20-15(18-8-7-10-3-5-11(24)6-4-10)21-16-19-13(22-23(14)16)12-2-1-9-25-12/h1-6,9,24H,7-8H2,(H3,17,18,19,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]Z241385 from human cloned adenosine A2A receptor expressed in CHO cells after 120 mins by scintillation counting				J Med Chem 52: 7640-52 (2009) Article DOI: 10.1021/jm900718w BindingDB Entry DOI: 10.7270/Q26T0MP5
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50300681 (2-(4-methoxyphenyl)-5-methyl-2H-pyrazolo[4,3-d]pyr...) Show SMILES COc1ccc(cc1)-n1cc2nc(C)[nH]c(=O)c2n1 Show InChI InChI=1S/C13H12N4O2/c1-8-14-11-7-17(16-12(11)13(18)15-8)9-3-5-10(19-2)6-4-9/h3-7H,1-2H3,(H,14,15,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Antagonist activity at human cloned adenosine A3 receptor expressed in CHO cells assessed as inhibition of Cl-IB-MECA-inhibited [3H]cAMP production b...				J Med Chem 52: 7640-52 (2009) Article DOI: 10.1021/jm900718w BindingDB Entry DOI: 10.7270/Q26T0MP5
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50300684 (5-methyl-2-p-tolyl-2H-pyrazolo[4,3-d]pyrimidin-7(6...) Show SMILES Cc1ccc(cc1)-n1cc2nc(C)[nH]c(=O)c2n1 Show InChI InChI=1S/C13H12N4O/c1-8-3-5-10(6-4-8)17-7-11-12(16-17)13(18)15-9(2)14-11/h3-7H,1-2H3,(H,14,15,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cells after 120 mins by scintillation counting				J Med Chem 52: 7640-52 (2009) Article DOI: 10.1021/jm900718w BindingDB Entry DOI: 10.7270/Q26T0MP5
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50300682 (5-ethyl-2-(4-methoxyphenyl)-2H-pyrazolo[4,3-d]pyri...) Show SMILES CCc1nc2cn(nc2c(=O)[nH]1)-c1ccc(OC)cc1 Show InChI InChI=1S/C14H14N4O2/c1-3-12-15-11-8-18(17-13(11)14(19)16-12)9-4-6-10(20-2)7-5-9/h4-8H,3H2,1-2H3,(H,15,16,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cells after 120 mins by scintillation counting				J Med Chem 52: 7640-52 (2009) Article DOI: 10.1021/jm900718w BindingDB Entry DOI: 10.7270/Q26T0MP5
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50300678 (5-methyl-2-phenyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H...) Show SMILES Cc1nc2cn(nc2c(=O)[nH]1)-c1ccccc1 Show InChI InChI=1S/C12H10N4O/c1-8-13-10-7-16(9-5-3-2-4-6-9)15-11(10)12(17)14-8/h2-7H,1H3,(H,13,14,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cells after 120 mins by scintillation counting				J Med Chem 52: 7640-52 (2009) Article DOI: 10.1021/jm900718w BindingDB Entry DOI: 10.7270/Q26T0MP5
					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM21190 (4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...) Show SMILES Nc1nc(NCCc2ccc(O)cc2)nc2nc(nn12)-c1ccco1 Show InChI InChI=1S/C16H15N7O2/c17-14-20-15(18-8-7-10-3-5-11(24)6-4-10)21-16-19-13(22-23(14)16)12-2-1-9-25-12/h1-6,9,24H,7-8H2,(H3,17,18,19,20,21,22)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Similars	Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-stimulated [3H]cAMP production by scintilla...				J Med Chem 52: 7640-52 (2009) Article DOI: 10.1021/jm900718w BindingDB Entry DOI: 10.7270/Q26T0MP5
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50300684 (5-methyl-2-p-tolyl-2H-pyrazolo[4,3-d]pyrimidin-7(6...) Show SMILES Cc1ccc(cc1)-n1cc2nc(C)[nH]c(=O)c2n1 Show InChI InChI=1S/C13H12N4O/c1-8-3-5-10(6-4-8)17-7-11-12(16-17)13(18)15-9(2)14-11/h3-7H,1-2H3,(H,14,15,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Antagonist activity at human cloned adenosine A3 receptor expressed in CHO cells assessed as inhibition of Cl-IB-MECA-inhibited [3H]cAMP production b...				J Med Chem 52: 7640-52 (2009) Article DOI: 10.1021/jm900718w BindingDB Entry DOI: 10.7270/Q26T0MP5
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50300679 (5-ethyl-2-phenyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)...) Show SMILES CCc1nc2cn(nc2c(=O)[nH]1)-c1ccccc1 Show InChI InChI=1S/C13H12N4O/c1-2-11-14-10-8-17(9-6-4-3-5-7-9)16-12(10)13(18)15-11/h3-8H,2H2,1H3,(H,14,15,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cells after 120 mins by scintillation counting				J Med Chem 52: 7640-52 (2009) Article DOI: 10.1021/jm900718w BindingDB Entry DOI: 10.7270/Q26T0MP5
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50300680 (2-(4-methoxyphenyl)-2H-pyrazolo[4,3-d]pyrimidin-7(...) Show SMILES COc1ccc(cc1)-n1cc2nc[nH]c(=O)c2n1 Show InChI InChI=1S/C12H10N4O2/c1-18-9-4-2-8(3-5-9)16-6-10-11(15-16)12(17)14-7-13-10/h2-7H,1H3,(H,13,14,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cells after 120 mins by scintillation counting				J Med Chem 52: 7640-52 (2009) Article DOI: 10.1021/jm900718w BindingDB Entry DOI: 10.7270/Q26T0MP5
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50300682 (5-ethyl-2-(4-methoxyphenyl)-2H-pyrazolo[4,3-d]pyri...) Show SMILES CCc1nc2cn(nc2c(=O)[nH]1)-c1ccc(OC)cc1 Show InChI InChI=1S/C14H14N4O2/c1-3-12-15-11-8-18(17-13(11)14(19)16-12)9-4-6-10(20-2)7-5-9/h4-8H,3H2,1-2H3,(H,15,16,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Antagonist activity at human cloned adenosine A3 receptor expressed in CHO cells assessed as inhibition of Cl-IB-MECA-inhibited [3H]cAMP production b...				J Med Chem 52: 7640-52 (2009) Article DOI: 10.1021/jm900718w BindingDB Entry DOI: 10.7270/Q26T0MP5
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50300685 (5-methyl-2-m-tolyl-2H-pyrazolo[4,3-d]pyrimidin-7(6...) Show SMILES Cc1cccc(c1)-n1cc2nc(C)[nH]c(=O)c2n1 Show InChI InChI=1S/C13H12N4O/c1-8-4-3-5-10(6-8)17-7-11-12(16-17)13(18)15-9(2)14-11/h3-7H,1-2H3,(H,14,15,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cells after 120 mins by scintillation counting				J Med Chem 52: 7640-52 (2009) Article DOI: 10.1021/jm900718w BindingDB Entry DOI: 10.7270/Q26T0MP5
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50300678 (5-methyl-2-phenyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H...) Show SMILES Cc1nc2cn(nc2c(=O)[nH]1)-c1ccccc1 Show InChI InChI=1S/C12H10N4O/c1-8-13-10-7-16(9-5-3-2-4-6-9)15-11(10)12(17)14-8/h2-7H,1H3,(H,13,14,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	87	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Antagonist activity at human cloned adenosine A3 receptor expressed in CHO cells assessed as inhibition of Cl-IB-MECA-inhibited [3H]cAMP production b...				J Med Chem 52: 7640-52 (2009) Article DOI: 10.1021/jm900718w BindingDB Entry DOI: 10.7270/Q26T0MP5
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM21190 (4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...) Show SMILES Nc1nc(NCCc2ccc(O)cc2)nc2nc(nn12)-c1ccco1 Show InChI InChI=1S/C16H15N7O2/c17-14-20-15(18-8-7-10-3-5-11(24)6-4-10)21-16-19-13(22-23(14)16)12-2-1-9-25-12/h1-6,9,24H,7-8H2,(H3,17,18,19,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Similars	Article PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]DPCPX from human cloned adenosine A1 receptor expressed in CHO cells after 120 mins by scintillation counting				J Med Chem 52: 7640-52 (2009) Article DOI: 10.1021/jm900718w BindingDB Entry DOI: 10.7270/Q26T0MP5
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50300677 (2-phenyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one | C...) Show SMILES O=c1[nH]cnc2cn(nc12)-c1ccccc1 Show InChI InChI=1S/C11H8N4O/c16-11-10-9(12-7-13-11)6-15(14-10)8-4-2-1-3-5-8/h1-7H,(H,12,13,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	185	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cells after 120 mins by scintillation counting				J Med Chem 52: 7640-52 (2009) Article DOI: 10.1021/jm900718w BindingDB Entry DOI: 10.7270/Q26T0MP5
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50300679 (5-ethyl-2-phenyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)...) Show SMILES CCc1nc2cn(nc2c(=O)[nH]1)-c1ccccc1 Show InChI InChI=1S/C13H12N4O/c1-2-11-14-10-8-17(9-6-4-3-5-7-9)16-12(10)13(18)15-11/h3-8H,2H2,1H3,(H,14,15,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	245	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Antagonist activity at human cloned adenosine A3 receptor expressed in CHO cells assessed as inhibition of Cl-IB-MECA-inhibited [3H]cAMP production b...				J Med Chem 52: 7640-52 (2009) Article DOI: 10.1021/jm900718w BindingDB Entry DOI: 10.7270/Q26T0MP5
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50300683 (5-benzyl-2-(4-methoxyphenyl)-2H-pyrazolo[4,3-d]pyr...) Show SMILES COc1ccc(cc1)-n1cc2nc(Cc3ccccc3)[nH]c(=O)c2n1 Show InChI InChI=1S/C19H16N4O2/c1-25-15-9-7-14(8-10-15)23-12-16-18(22-23)19(24)21-17(20-16)11-13-5-3-2-4-6-13/h2-10,12H,11H2,1H3,(H,20,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cells after 120 mins by scintillation counting				J Med Chem 52: 7640-52 (2009) Article DOI: 10.1021/jm900718w BindingDB Entry DOI: 10.7270/Q26T0MP5
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50300680 (2-(4-methoxyphenyl)-2H-pyrazolo[4,3-d]pyrimidin-7(...) Show SMILES COc1ccc(cc1)-n1cc2nc[nH]c(=O)c2n1 Show InChI InChI=1S/C12H10N4O2/c1-18-9-4-2-8(3-5-9)16-6-10-11(15-16)12(17)14-7-13-10/h2-7H,1H3,(H,13,14,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Antagonist activity at human cloned adenosine A3 receptor expressed in CHO cells assessed as inhibition of Cl-IB-MECA-inhibited [3H]cAMP production b...				J Med Chem 52: 7640-52 (2009) Article DOI: 10.1021/jm900718w BindingDB Entry DOI: 10.7270/Q26T0MP5
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50300685 (5-methyl-2-m-tolyl-2H-pyrazolo[4,3-d]pyrimidin-7(6...) Show SMILES Cc1cccc(c1)-n1cc2nc(C)[nH]c(=O)c2n1 Show InChI InChI=1S/C13H12N4O/c1-8-4-3-5-10(6-8)17-7-11-12(16-17)13(18)15-9(2)14-11/h3-7H,1-2H3,(H,14,15,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	354	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Antagonist activity at human cloned adenosine A3 receptor expressed in CHO cells assessed as inhibition of Cl-IB-MECA-inhibited [3H]cAMP production b...				J Med Chem 52: 7640-52 (2009) Article DOI: 10.1021/jm900718w BindingDB Entry DOI: 10.7270/Q26T0MP5
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50300677 (2-phenyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one | C...) Show SMILES O=c1[nH]cnc2cn(nc12)-c1ccccc1 Show InChI InChI=1S/C11H8N4O/c16-11-10-9(12-7-13-11)6-15(14-10)8-4-2-1-3-5-8/h1-7H,(H,12,13,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	725	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Antagonist activity at human cloned adenosine A3 receptor expressed in CHO cells assessed as inhibition of Cl-IB-MECA-inhibited [3H]cAMP production b...				J Med Chem 52: 7640-52 (2009) Article DOI: 10.1021/jm900718w BindingDB Entry DOI: 10.7270/Q26T0MP5
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50300683 (5-benzyl-2-(4-methoxyphenyl)-2H-pyrazolo[4,3-d]pyr...) Show SMILES COc1ccc(cc1)-n1cc2nc(Cc3ccccc3)[nH]c(=O)c2n1 Show InChI InChI=1S/C19H16N4O2/c1-25-15-9-7-14(8-10-15)23-12-16-18(22-23)19(24)21-17(20-16)11-13-5-3-2-4-6-13/h2-10,12H,11H2,1H3,(H,20,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	850	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Antagonist activity at human cloned adenosine A3 receptor expressed in CHO cells assessed as inhibition of Cl-IB-MECA-inhibited [3H]cAMP production b...				J Med Chem 52: 7640-52 (2009) Article DOI: 10.1021/jm900718w BindingDB Entry DOI: 10.7270/Q26T0MP5
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50300686 (5-benzyl-2-phenyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H...) Show SMILES O=c1[nH]c(Cc2ccccc2)nc2cn(nc12)-c1ccccc1 Show InChI InChI=1S/C18H14N4O/c23-18-17-15(12-22(21-17)14-9-5-2-6-10-14)19-16(20-18)11-13-7-3-1-4-8-13/h1-10,12H,11H2,(H,19,20,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cells after 120 mins by scintillation counting				J Med Chem 52: 7640-52 (2009) Article DOI: 10.1021/jm900718w BindingDB Entry DOI: 10.7270/Q26T0MP5
					More data for this Ligand-Target Pair