Compile Data Set for Download or QSAR

Found 62 hits Enz. Inhib. hit(s) with all data for entry = 50031317   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311061 (3-(3-fluoro-9H-benzo[f]imidazo[1,5-a][1,2,4]triazo...) Show SMILES Cc1nc(no1)-c1ncn-2c1Cn1ncnc1-c1cc(F)ccc-21 Show InChI InChI=1S/C15H10FN7O/c1-8-20-14(21-24-8)13-12-5-23-15(17-6-19-23)10-4-9(16)2-3-11(10)22(12)7-18-13/h2-4,6-7H,5H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311052 (CHEMBL1079870 | ethyl 3-fluoro-9H-benzo[f]imidazo[...) Show SMILES CCOC(=O)c1ncn-2c1Cn1ncnc1-c1cc(F)ccc-21 Show InChI InChI=1S/C15H12FN5O2/c1-2-23-15(22)13-12-6-21-14(17-7-19-21)10-5-9(16)3-4-11(10)20(12)8-18-13/h3-5,7-8H,2,6H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from human GABAalpha5beta3gamma2 receptor expressed in insect SF9 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311048 (10-chloro-3-fluoro-9H-benzo[f]imidazo[1,5-a][1,2,4...) Show SMILES Fc1ccc-2c(c1)-c1ncnn1Cc1c(Cl)ncn-21 Show InChI InChI=1S/C12H7ClFN5/c13-11-10-4-19-12(15-5-17-19)8-3-7(14)1-2-9(8)18(10)6-16-11/h1-3,5-6H,4H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from human GABAalpha5beta3gamma2 receptor expressed in insect SF9 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311049 (10-chloro-9H-benzo[f]imidazo[1,5-a][1,2,4]triazolo...) Show SMILES Clc1ncn-2c1Cn1ncnc1-c1ccccc-21 Show InChI InChI=1S/C12H8ClN5/c13-11-10-5-18-12(14-6-16-18)8-3-1-2-4-9(8)17(10)7-15-11/h1-4,6-7H,5H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311074 (4-fluoro-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4...) Show SMILES Cc1ncn-2c1Cn1ncnc1-c1c(F)cccc-21 Show InChI InChI=1S/C13H10FN5/c1-8-11-5-19-13(15-6-17-19)12-9(14)3-2-4-10(12)18(11)7-16-8/h2-4,6-7H,5H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311036 (10-chloro-3-(difluoromethyl)-9H-benzo[f]imidazo[1,...) Show SMILES FC(F)c1ccc-2c(c1)-c1ncnn1Cc1c(Cl)ncn-21 Show InChI InChI=1S/C13H8ClF2N5/c14-11-10-4-21-13(17-5-19-21)8-3-7(12(15)16)1-2-9(8)20(10)6-18-11/h1-3,5-6,12H,4H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311037 (10-chloro-3-cyclopropyl-9H-benzo[f]imidazo[1,5-a][...) Show SMILES Clc1ncn-2c1Cn1ncnc1-c1cc(ccc-21)C1CC1 Show InChI InChI=1S/C15H12ClN5/c16-14-13-6-21-15(17-7-19-21)11-5-10(9-1-2-9)3-4-12(11)20(13)8-18-14/h3-5,7-9H,1-2,6H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311075 (4-chloro-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4...) Show SMILES Cc1ncn-2c1Cn1ncnc1-c1c(Cl)cccc-21 Show InChI InChI=1S/C13H10ClN5/c1-8-11-5-19-13(15-6-17-19)12-9(14)3-2-4-10(12)18(11)7-16-8/h2-4,6-7H,5H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311033 (3-bromo-10-chloro-9H-benzo[f]imidazo[1,5-a][1,2,4]...) Show SMILES Clc1ncn-2c1Cn1ncnc1-c1cc(Br)ccc-21 Show InChI InChI=1S/C12H7BrClN5/c13-7-1-2-9-8(3-7)12-15-5-17-19(12)4-10-11(14)16-6-18(9)10/h1-3,5-6H,4H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311057 (3-chloro-10-propyl-9H-benzo[f]imidazo[1,5-a][1,2,4...) Show SMILES CCCc1ncn-2c1Cn1ncnc1-c1cc(Cl)ccc-21 Show InChI InChI=1S/C15H14ClN5/c1-2-3-12-14-7-21-15(17-8-19-21)11-6-10(16)4-5-13(11)20(14)9-18-12/h4-6,8-9H,2-3,7H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311035 (10-chloro-3-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4...) Show SMILES Cc1ccc-2c(c1)-c1ncnn1Cc1c(Cl)ncn-21 Show InChI InChI=1S/C13H10ClN5/c1-8-2-3-10-9(4-8)13-15-6-17-19(13)5-11-12(14)16-7-18(10)11/h2-4,6-7H,5H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311071 (3-(difluoromethoxy)-10-methyl-9H-benzo[f]imidazo[1...) Show SMILES Cc1ncn-2c1Cn1ncnc1-c1cc(OC(F)F)ccc-21 Show InChI InChI=1S/C14H11F2N5O/c1-8-12-5-21-13(17-6-19-21)10-4-9(22-14(15)16)2-3-11(10)20(12)7-18-8/h2-4,6-7,14H,5H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311047 (3,10-dichloro-9H-benzo[f]imidazo[1,5-a][1,2,4]tria...) Show SMILES Clc1ncn-2c1Cn1ncnc1-c1cc(Cl)ccc-21 Show InChI InChI=1S/C12H7Cl2N5/c13-7-1-2-9-8(3-7)12-15-5-17-19(12)4-10-11(14)16-6-18(9)10/h1-3,5-6H,4H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311068 (3-(difluoromethyl)-10-methyl-9H-benzo[f]imidazo[1,...) Show SMILES Cc1ncn-2c1Cn1ncnc1-c1cc(ccc-21)C(F)F Show InChI InChI=1S/C14H11F2N5/c1-8-12-5-21-14(17-6-19-21)10-4-9(13(15)16)2-3-11(10)20(12)7-18-8/h2-4,6-7,13H,5H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311039 (10-chloro-N-cyclopropyl-9H-benzo[f]imidazo[1,5-a][...) Show SMILES Clc1ncn-2c1Cn1ncnc1-c1cc(NC3CC3)ccc-21 Show InChI InChI=1S/C15H13ClN6/c16-14-13-6-22-15(17-7-19-22)11-5-10(20-9-1-2-9)3-4-12(11)21(13)8-18-14/h3-5,7-9,20H,1-2,6H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311034 (10-chloro-9H-benzo[f]imidazo[1,5-a][1,2,4]triazolo...) Show SMILES Clc1ncn-2c1Cn1ncnc1-c1cc(ccc-21)C#N Show InChI InChI=1S/C13H7ClN6/c14-12-11-5-20-13(16-6-18-20)9-3-8(4-15)1-2-10(9)19(11)7-17-12/h1-3,6-7H,5H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311054 (1-(3-chloro-9H-benzo[f]imidazo[1,5-a][1,2,4]triazo...) Show SMILES CCC(=O)c1ncn-2c1Cn1ncnc1-c1cc(Cl)ccc-21 Show InChI InChI=1S/C15H12ClN5O/c1-2-13(22)14-12-6-21-15(17-7-19-21)10-5-9(16)3-4-11(10)20(12)8-18-14/h3-5,7-8H,2,6H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from human GABAalpha5beta3gamma2 receptor expressed in insect SF9 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311064 (10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4]triazolo...) Show SMILES Cc1ncn-2c1Cn1ncnc1-c1ccccc-21 Show InChI InChI=1S/C13H11N5/c1-9-12-6-18-13(14-7-16-18)10-4-2-3-5-11(10)17(12)8-15-9/h2-5,7-8H,6H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311040 (CHEMBL1081493 | N-(10-chloro-9H-benzo[f]imidazo[1,...) Show SMILES CC(=O)Nc1ccc-2c(c1)-c1ncnn1Cc1c(Cl)ncn-21 Show InChI InChI=1S/C14H11ClN6O/c1-8(22)19-9-2-3-11-10(4-9)14-16-6-18-21(14)5-12-13(15)17-7-20(11)12/h2-4,6-7H,5H2,1H3,(H,19,22)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311065 (3-fluoro-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4...) Show SMILES Cc1ncn-2c1Cn1ncnc1-c1cc(F)ccc-21 Show InChI InChI=1S/C13H10FN5/c1-8-12-5-19-13(15-6-17-19)10-4-9(14)2-3-11(10)18(12)7-16-8/h2-4,6-7H,5H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311046 (3-chloro-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4...) Show SMILES Cc1ncn-2c1Cn1ncnc1-c1cc(Cl)ccc-21 Show InChI InChI=1S/C13H10ClN5/c1-8-12-5-19-13(15-6-17-19)10-4-9(14)2-3-11(10)18(12)7-16-8/h2-4,6-7H,5H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311056 (10-(1,1-difluoropropyl)-3-fluoro-9H-benzo[f]imidaz...) Show SMILES CCC(F)(F)c1ncn-2c1Cn1ncnc1-c1cc(F)ccc-21 Show InChI InChI=1S/C15H12F3N5/c1-2-15(17,18)13-12-6-23-14(19-7-21-23)10-5-9(16)3-4-11(10)22(12)8-20-13/h3-5,7-8H,2,6H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311062 (3-bromo-10-(thiophen-2-yl)-9H-benzo[f]imidazo[1,5-...) Show SMILES Brc1ccc-2c(c1)-c1ncnn1Cc1c(ncn-21)-c1cccs1 Show InChI InChI=1S/C16H10BrN5S/c17-10-3-4-12-11(6-10)16-18-8-20-22(16)7-13-15(19-9-21(12)13)14-2-1-5-23-14/h1-6,8-9H,7H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311066 (3-iodo-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4]t...) Show SMILES Cc1ncn-2c1Cn1ncnc1-c1cc(I)ccc-21 Show InChI InChI=1S/C13H10IN5/c1-8-12-5-19-13(15-6-17-19)10-4-9(14)2-3-11(10)18(12)7-16-8/h2-4,6-7H,5H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311045 (3-bromo-10-(difluoromethyl)-9H-benzo[f]imidazo[1,5...) Show SMILES FC(F)c1ncn-2c1Cn1ncnc1-c1cc(Br)ccc-21 Show InChI InChI=1S/C13H8BrF2N5/c14-7-1-2-9-8(3-7)13-17-5-19-21(13)4-10-11(12(15)16)18-6-20(9)10/h1-3,5-6,12H,4H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair				3D Structure (crystal)
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311044 (3-chloro-10-(difluoromethyl)-9H-benzo[f]imidazo[1,...) Show SMILES FC(F)c1ncn-2c1Cn1ncnc1-c1cc(Cl)ccc-21 Show InChI InChI=1S/C13H8ClF2N5/c14-7-1-2-9-8(3-7)13-17-5-19-21(13)4-10-11(12(15)16)18-6-20(9)10/h1-3,5-6,12H,4H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50310939 (3-bromo-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4]...) Show SMILES Cc1ncn-2c1Cn1ncnc1-c1cc(Br)ccc-21 Show InChI InChI=1S/C13H10BrN5/c1-8-12-5-19-13(15-6-17-19)10-4-9(14)2-3-11(10)18(12)7-16-8/h2-4,6-7H,5H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311038 (10-chloro-3-phenyl-9H-benzo[f]imidazo[1,5-a][1,2,4...) Show SMILES Clc1ncn-2c1Cn1ncnc1-c1cc(ccc-21)-c1ccccc1 Show InChI InChI=1S/C18H12ClN5/c19-17-16-9-24-18(20-10-22-24)14-8-13(12-4-2-1-3-5-12)6-7-15(14)23(16)11-21-17/h1-8,10-11H,9H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311059 (3-chloro-9H-benzo[f]imidazo[1,5-a][1,2,4]triazolo[...) Show SMILES Clc1ccc-2c(c1)-c1ncnn1Cc1c(ncn-21)C#N Show InChI InChI=1S/C13H7ClN6/c14-8-1-2-11-9(3-8)13-16-6-18-20(13)5-12-10(4-15)17-7-19(11)12/h1-3,6-7H,5H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from human GABAalpha5beta3gamma2 receptor expressed in insect SF9 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311050 (9H-benzo[f]imidazo[1,5-a][1,2,4]triazolo[1,5-d][1,...) Show SMILES C1c2cncn2-c2ccccc2-c2ncnn12 Show InChI InChI=1S/C12H9N5/c1-2-4-11-10(3-1)12-14-7-15-17(12)6-9-5-13-8-16(9)11/h1-5,7-8H,6H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from human GABAalpha5beta3gamma2 receptor expressed in insect SF9 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311070 (3-methoxy-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,...) Show SMILES COc1ccc-2c(c1)-c1ncnn1Cc1c(C)ncn-21 Show InChI InChI=1S/C14H13N5O/c1-9-13-6-19-14(15-7-17-19)11-5-10(20-2)3-4-12(11)18(13)8-16-9/h3-5,7-8H,6H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311033 (3-bromo-10-chloro-9H-benzo[f]imidazo[1,5-a][1,2,4]...) Show SMILES Clc1ncn-2c1Cn1ncnc1-c1cc(Br)ccc-21 Show InChI InChI=1S/C12H7BrClN5/c13-7-1-2-9-8(3-7)12-15-5-17-19(12)4-10-11(14)16-6-18(9)10/h1-3,5-6H,4H2	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha3beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311067 (3,10-dimethyl-9H-benzo[f]imidazo[1,5-a][1,2,4]tria...) Show SMILES Cc1ncn-2c1Cn1ncnc1-c1cc(C)ccc-21 Show InChI InChI=1S/C14H13N5/c1-9-3-4-12-11(5-9)14-15-7-17-19(14)6-13-10(2)16-8-18(12)13/h3-5,7-8H,6H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311058 (3-chloro-10-cyclopropyl-9H-benzo[f]imidazo[1,5-a][...) Show SMILES Clc1ccc-2c(c1)-c1ncnn1Cc1c(ncn-21)C1CC1 Show InChI InChI=1S/C15H12ClN5/c16-10-3-4-12-11(5-10)15-17-7-19-21(15)6-13-14(9-1-2-9)18-8-20(12)13/h3-5,7-9H,1-2,6H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311063 (3-bromo-10-(1-methyl-1H-pyrazol-5-yl)-9H-benzo[f]i...) Show SMILES Cn1nccc1-c1ncn-2c1Cn1ncnc1-c1cc(Br)ccc-21 Show InChI InChI=1S/C16H12BrN7/c1-22-13(4-5-20-22)15-14-7-24-16(18-8-21-24)11-6-10(17)2-3-12(11)23(14)9-19-15/h2-6,8-9H,7H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311051 (3-fluoro-9H-benzo[f]imidazo[1,5-a][1,2,4]triazolo[...) Show SMILES Fc1ccc-2c(c1)-c1ncnn1Cc1cncn-21 Show InChI InChI=1S/C12H8FN5/c13-8-1-2-11-10(3-8)12-15-6-16-18(12)5-9-4-14-7-17(9)11/h1-4,6-7H,5H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from human GABAalpha5beta3gamma2 receptor expressed in insect SF9 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311043 (10-chloro-3-(1H-imidazol-1-yl)-9H-benzo[f]imidazo[...) Show SMILES Clc1ncn-2c1Cn1ncnc1-c1cc(ccc-21)-n1ccnc1 Show InChI InChI=1S/C15H10ClN7/c16-14-13-6-23-15(18-7-20-23)11-5-10(21-4-3-17-8-21)1-2-12(11)22(13)9-19-14/h1-5,7-9H,6H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311047 (3,10-dichloro-9H-benzo[f]imidazo[1,5-a][1,2,4]tria...) Show SMILES Clc1ncn-2c1Cn1ncnc1-c1cc(Cl)ccc-21 Show InChI InChI=1S/C12H7Cl2N5/c13-7-1-2-9-8(3-7)12-15-5-17-19(12)4-10-11(14)16-6-18(9)10/h1-3,5-6H,4H2	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha3beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311047 (3,10-dichloro-9H-benzo[f]imidazo[1,5-a][1,2,4]tria...) Show SMILES Clc1ncn-2c1Cn1ncnc1-c1cc(Cl)ccc-21 Show InChI InChI=1S/C12H7Cl2N5/c13-7-1-2-9-8(3-7)12-15-5-17-19(12)4-10-11(14)16-6-18(9)10/h1-3,5-6H,4H2	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha1beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311041 (CHEMBL1081494 | N-(10-chloro-9H-benzo[f]imidazo[1,...) Show SMILES Clc1ncn-2c1Cn1ncnc1-c1cc(NC(=O)C3CC3)ccc-21 Show InChI InChI=1S/C16H13ClN6O/c17-14-13-6-23-15(18-7-20-23)11-5-10(21-16(24)9-1-2-9)3-4-12(11)22(13)8-19-14/h3-5,7-9H,1-2,6H2,(H,21,24)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311046 (3-chloro-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4...) Show SMILES Cc1ncn-2c1Cn1ncnc1-c1cc(Cl)ccc-21 Show InChI InChI=1S/C13H10ClN5/c1-8-12-5-19-13(15-6-17-19)10-4-9(14)2-3-11(10)18(12)7-16-8/h2-4,6-7H,5H2,1H3	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha1beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311069 (10-methyl-3-(trifluoromethyl)-9H-benzo[f]imidazo[1...) Show SMILES Cc1ncn-2c1Cn1ncnc1-c1cc(ccc-21)C(F)(F)F Show InChI InChI=1S/C14H10F3N5/c1-8-12-5-22-13(18-6-20-22)10-4-9(14(15,16)17)2-3-11(10)21(12)7-19-8/h2-4,6-7H,5H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-2/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311047 (3,10-dichloro-9H-benzo[f]imidazo[1,5-a][1,2,4]tria...) Show SMILES Clc1ncn-2c1Cn1ncnc1-c1cc(Cl)ccc-21 Show InChI InChI=1S/C12H7Cl2N5/c13-7-1-2-9-8(3-7)12-15-5-17-19(12)4-10-11(14)16-6-18(9)10/h1-3,5-6H,4H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha2beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-2/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311033 (3-bromo-10-chloro-9H-benzo[f]imidazo[1,5-a][1,2,4]...) Show SMILES Clc1ncn-2c1Cn1ncnc1-c1cc(Br)ccc-21 Show InChI InChI=1S/C12H7BrClN5/c13-7-1-2-9-8(3-7)12-15-5-17-19(12)4-10-11(14)16-6-18(9)10/h1-3,5-6H,4H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha2beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311060 (3-chloro-10-(6-methylpyridin-2-yl)-9H-benzo[f]imid...) Show SMILES Cc1cccc(n1)-c1ncn-2c1Cn1ncnc1-c1cc(Cl)ccc-21 Show InChI InChI=1S/C18H13ClN6/c1-11-3-2-4-14(23-11)17-16-8-25-18(20-9-22-25)13-7-12(19)5-6-15(13)24(16)10-21-17/h2-7,9-10H,8H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311033 (3-bromo-10-chloro-9H-benzo[f]imidazo[1,5-a][1,2,4]...) Show SMILES Clc1ncn-2c1Cn1ncnc1-c1cc(Br)ccc-21 Show InChI InChI=1S/C12H7BrClN5/c13-7-1-2-9-8(3-7)12-15-5-17-19(12)4-10-11(14)16-6-18(9)10/h1-3,5-6H,4H2	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha1beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311044 (3-chloro-10-(difluoromethyl)-9H-benzo[f]imidazo[1,...) Show SMILES FC(F)c1ncn-2c1Cn1ncnc1-c1cc(Cl)ccc-21 Show InChI InChI=1S/C13H8ClF2N5/c14-7-1-2-9-8(3-7)13-17-5-19-21(13)4-10-11(12(15)16)18-6-20(9)10/h1-3,5-6,12H,4H2	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha3beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311072 (10-methyl-3-(trifluoromethoxy)-9H-benzo[f]imidazo[...) Show SMILES Cc1ncn-2c1Cn1ncnc1-c1cc(OC(F)(F)F)ccc-21 Show InChI InChI=1S/C14H10F3N5O/c1-8-12-5-22-13(18-6-20-22)10-4-9(23-14(15,16)17)2-3-11(10)21(12)7-19-8/h2-4,6-7H,5H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311044 (3-chloro-10-(difluoromethyl)-9H-benzo[f]imidazo[1,...) Show SMILES FC(F)c1ncn-2c1Cn1ncnc1-c1cc(Cl)ccc-21 Show InChI InChI=1S/C13H8ClF2N5/c14-7-1-2-9-8(3-7)13-17-5-19-21(13)4-10-11(12(15)16)18-6-20(9)10/h1-3,5-6,12H,4H2	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha1beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50311042 (CHEMBL1081495 | N-(10-chloro-9H-benzo[f]imidazo[1,...) Show SMILES CS(=O)(=O)Nc1ccc-2c(c1)-c1ncnn1Cc1c(Cl)ncn-21 Show InChI InChI=1S/C13H11ClN6O2S/c1-23(21,22)18-8-2-3-10-9(4-8)13-15-6-17-20(13)5-11-12(14)16-7-19(10)11/h2-4,6-7,18H,5H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]Flumazenil from cloned human GABAalpha5beta3gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 5940-4 (2009) Article DOI: 10.1016/j.bmcl.2009.08.053 BindingDB Entry DOI: 10.7270/Q27944TT
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 62 total )  |  Next  |  Last  >>

Jump to: