Compile Data Set for Download or QSAR

Found 20 hits Enz. Inhib. hit(s) with all data for entry = 50031775   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50318887 ((5S,5aS)-5-isobutyl-3-(1H-tetrazol-5-yl)-4,4a,5,5a...) Show SMILES CC(C)C[C@H]1C2Cc3c(n[nH]c3[C@@H]12)-c1nnn[nH]1 |r| Show InChI InChI=1S/C12H16N6/c1-5(2)3-6-7-4-8-10(9(6)7)13-14-11(8)12-15-17-18-16-12/h5-7,9H,3-4H2,1-2H3,(H,13,14)(H,15,16,17,18)/t6-,7?,9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.31E+4	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by HTRF assay				Bioorg Med Chem Lett 20: 2797-800 (2010) Article DOI: 10.1016/j.bmcl.2010.03.062 BindingDB Entry DOI: 10.7270/Q2X0676V
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50318904 ((4aR,5R,5aS)-5-allyl-3-(1H-tetrazol-5-yl)-4,4a,5,5...) Show SMILES C=CC[C@@H]1[C@H]2Cc3c([nH]nc3-c3nnn[nH]3)[C@@H]12 |r| Show InChI InChI=1S/C11H12N6/c1-2-3-5-6-4-7-9(8(5)6)12-13-10(7)11-14-16-17-15-11/h2,5-6,8H,1,3-4H2,(H,12,13)(H,14,15,16,17)/t5-,6-,8+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.42E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by HTRF assay				Bioorg Med Chem Lett 20: 2797-800 (2010) Article DOI: 10.1016/j.bmcl.2010.03.062 BindingDB Entry DOI: 10.7270/Q2X0676V
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50318889 ((4aR,5R,5aS)-5-butyl-3-(1H-tetrazol-5-yl)-4,4a,5,5...) Show SMILES CCCC[C@@H]1[C@H]2Cc3c([nH]nc3-c3nnn[nH]3)[C@@H]12 |r| Show InChI InChI=1S/C12H16N6/c1-2-3-4-6-7-5-8-10(9(6)7)13-14-11(8)12-15-17-18-16-12/h6-7,9H,2-5H2,1H3,(H,13,14)(H,15,16,17,18)/t6-,7-,9+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.75E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by HTRF assay				Bioorg Med Chem Lett 20: 2797-800 (2010) Article DOI: 10.1016/j.bmcl.2010.03.062 BindingDB Entry DOI: 10.7270/Q2X0676V
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50318890 ((4aS,5R,5aR)-5-(methoxymethyl)-3-(1H-tetrazol-5-yl...) Show SMILES COC[C@@H]1[C@H]2Cc3c([nH]nc3-c3nnn[nH]3)[C@@H]12 |r| Show InChI InChI=1S/C10H12N6O/c1-17-3-6-4-2-5-8(7(4)6)11-12-9(5)10-13-15-16-14-10/h4,6-7H,2-3H2,1H3,(H,11,12)(H,13,14,15,16)/t4-,6-,7-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.83E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by HTRF assay				Bioorg Med Chem Lett 20: 2797-800 (2010) Article DOI: 10.1016/j.bmcl.2010.03.062 BindingDB Entry DOI: 10.7270/Q2X0676V
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50318891 ((4aS,5aR)-5,5-dimethyl-3-(1H-tetrazol-5-yl)-4,4a,5...) Show SMILES CC1(C)[C@H]2Cc3c(n[nH]c3[C@@H]12)-c1nnn[nH]1 |r| Show InChI InChI=1S/C10H12N6/c1-10(2)5-3-4-7(6(5)10)11-12-8(4)9-13-15-16-14-9/h5-6H,3H2,1-2H3,(H,11,12)(H,13,14,15,16)/t5-,6-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.86E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by HTRF assay				Bioorg Med Chem Lett 20: 2797-800 (2010) Article DOI: 10.1016/j.bmcl.2010.03.062 BindingDB Entry DOI: 10.7270/Q2X0676V
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50318892 ((2'R,4'S)-7'-(1H-1,2,3,4-tetrazol-5-yl)-8',9'-diaz...) Show SMILES C1CCC2(C1)[C@H]1Cc3c([nH]nc3-c3nnn[nH]3)[C@@H]21 |r| Show InChI InChI=1S/C12H14N6/c1-2-4-12(3-1)7-5-6-9(8(7)12)13-14-10(6)11-15-17-18-16-11/h7-8H,1-5H2,(H,13,14)(H,15,16,17,18)/t7-,8-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by HTRF assay				Bioorg Med Chem Lett 20: 2797-800 (2010) Article DOI: 10.1016/j.bmcl.2010.03.062 BindingDB Entry DOI: 10.7270/Q2X0676V
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM23515 (CHEMBL573 | Niacin | Nicotinic Acid | [5, 6-3H]-ni...) Show SMILES OC(=O)c1cccnc1 Show InChI InChI=1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by HTRF assay				Bioorg Med Chem Lett 20: 2797-800 (2010) Article DOI: 10.1016/j.bmcl.2010.03.062 BindingDB Entry DOI: 10.7270/Q2X0676V
					More data for this Ligand-Target Pair				3D Structure (crystal)
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50273099 (3-(1H-tetrazol-5-yl)-1,4,5,6-tetrahydrocyclopenta[...) Show SMILES C1Cc2[nH]nc(c2C1)-c1nnn[nH]1 Show InChI InChI=1S/C7H8N6/c1-2-4-5(3-1)8-9-6(4)7-10-12-13-11-7/h1-3H2,(H,8,9)(H,10,11,12,13)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	286	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by HTRF assay				Bioorg Med Chem Lett 20: 2797-800 (2010) Article DOI: 10.1016/j.bmcl.2010.03.062 BindingDB Entry DOI: 10.7270/Q2X0676V
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50318893 ((+/-)-3-(1H-tetrazol-5-yl)-4,4a,5,5a-tetrahydro-1H...) Show SMILES C1C2Cc3c(n[nH]c3C12)-c1nnn[nH]1 Show InChI InChI=1S/C8H8N6/c1-3-2-5-6(4(1)3)9-10-7(5)8-11-13-14-12-8/h3-4H,1-2H2,(H,9,10)(H,11,12,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	210	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by HTRF assay				Bioorg Med Chem Lett 20: 2797-800 (2010) Article DOI: 10.1016/j.bmcl.2010.03.062 BindingDB Entry DOI: 10.7270/Q2X0676V
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50318894 ((+)-3-(1H-tetrazol-5-yl)-4,4a,5,5a-tetrahydro-1H-c...) Show SMILES C1[C@H]2Cc3c(n[nH]c3[C@@H]12)-c1nnn[nH]1 |r| Show InChI InChI=1S/C8H8N6/c1-3-2-5-6(4(1)3)9-10-7(5)8-11-13-14-12-8/h3-4H,1-2H2,(H,9,10)(H,11,12,13,14)/t3-,4-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by HTRF assay				Bioorg Med Chem Lett 20: 2797-800 (2010) Article DOI: 10.1016/j.bmcl.2010.03.062 BindingDB Entry DOI: 10.7270/Q2X0676V
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50318895 ((1S,1aS,5aR)-1-Methyl-4-(1H-tetrazol-5-yl)-1a,2,5,...) Show SMILES C[C@H]1[C@H]2Cc3c(n[nH]c3[C@@H]12)-c1nnn[nH]1 |r| Show InChI InChI=1S/C9H10N6/c1-3-4-2-5-7(6(3)4)10-11-8(5)9-12-14-15-13-9/h3-4,6H,2H2,1H3,(H,10,11)(H,12,13,14,15)/t3-,4+,6-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.35E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by HTRF assay				Bioorg Med Chem Lett 20: 2797-800 (2010) Article DOI: 10.1016/j.bmcl.2010.03.062 BindingDB Entry DOI: 10.7270/Q2X0676V
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50318896 ((1R,1aS,5aR)-1-Methyl-4-(1H-tetrazol-5-yl)-1a,2,5,...) Show SMILES C[C@@H]1[C@H]2Cc3c(n[nH]c3[C@@H]12)-c1nnn[nH]1 |r| Show InChI InChI=1S/C9H10N6/c1-3-4-2-5-7(6(3)4)10-11-8(5)9-12-14-15-13-9/h3-4,6H,2H2,1H3,(H,10,11)(H,12,13,14,15)/t3-,4-,6+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	244	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by HTRF assay				Bioorg Med Chem Lett 20: 2797-800 (2010) Article DOI: 10.1016/j.bmcl.2010.03.062 BindingDB Entry DOI: 10.7270/Q2X0676V
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50318897 ((4aR,5R,5aS)-5-ethyl-3-(1H-tetrazol-5-yl)-4,4a,5,5...) Show SMILES CC[C@@H]1[C@H]2Cc3c([nH]nc3-c3nnn[nH]3)[C@@H]12 |r| Show InChI InChI=1S/C10H12N6/c1-2-4-5-3-6-8(7(4)5)11-12-9(6)10-13-15-16-14-10/h4-5,7H,2-3H2,1H3,(H,11,12)(H,13,14,15,16)/t4-,5-,7+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	504	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by HTRF assay				Bioorg Med Chem Lett 20: 2797-800 (2010) Article DOI: 10.1016/j.bmcl.2010.03.062 BindingDB Entry DOI: 10.7270/Q2X0676V
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50318898 ((4aR,5S,5aR)-3-(1H-tetrazol-5-yl)-5-vinyl-4,4a,5,5...) Show SMILES C=C[C@H]1[C@H]2Cc3c([nH]nc3-c3nnn[nH]3)[C@@H]12 |r| Show InChI InChI=1S/C10H10N6/c1-2-4-5-3-6-8(7(4)5)11-12-9(6)10-13-15-16-14-10/h2,4-5,7H,1,3H2,(H,11,12)(H,13,14,15,16)/t4-,5+,7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by HTRF assay				Bioorg Med Chem Lett 20: 2797-800 (2010) Article DOI: 10.1016/j.bmcl.2010.03.062 BindingDB Entry DOI: 10.7270/Q2X0676V
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50318899 ((4aR,5R,5aR)-3-(1H-tetrazol-5-yl)-5-vinyl-4,4a,5,5...) Show SMILES C=C[C@@H]1[C@H]2Cc3c([nH]nc3-c3nnn[nH]3)[C@@H]12 |r| Show InChI InChI=1S/C10H10N6/c1-2-4-5-3-6-8(7(4)5)11-12-9(6)10-13-15-16-14-10/h2,4-5,7H,1,3H2,(H,11,12)(H,13,14,15,16)/t4-,5-,7+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	156	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by HTRF assay				Bioorg Med Chem Lett 20: 2797-800 (2010) Article DOI: 10.1016/j.bmcl.2010.03.062 BindingDB Entry DOI: 10.7270/Q2X0676V
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50318900 ((4aR,5R,5aR)-5-cyclopropyl-3-(1H-tetrazol-5-yl)-4,...) Show SMILES C1CC1[C@@H]1[C@H]2Cc3c(n[nH]c3[C@@H]12)-c1nnn[nH]1 |r| Show InChI InChI=1S/C11H12N6/c1-2-4(1)7-5-3-6-9(8(5)7)12-13-10(6)11-14-16-17-15-11/h4-5,7-8H,1-3H2,(H,12,13)(H,14,15,16,17)/t5-,7-,8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	507	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by HTRF assay				Bioorg Med Chem Lett 20: 2797-800 (2010) Article DOI: 10.1016/j.bmcl.2010.03.062 BindingDB Entry DOI: 10.7270/Q2X0676V
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50318901 ((1R,1aS,5aR)-1-Propyl-4-(1H-tetrazol-5-yl)-1a,2,5,...) Show SMILES CCC[C@@H]1[C@H]2Cc3c([nH]nc3-c3nnn[nH]3)[C@@H]12 |r| Show InChI InChI=1S/C11H14N6/c1-2-3-5-6-4-7-9(8(5)6)12-13-10(7)11-14-16-17-15-11/h5-6,8H,2-4H2,1H3,(H,12,13)(H,14,15,16,17)/t5-,6-,8+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	541	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by HTRF assay				Bioorg Med Chem Lett 20: 2797-800 (2010) Article DOI: 10.1016/j.bmcl.2010.03.062 BindingDB Entry DOI: 10.7270/Q2X0676V
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50318902 ((4aR,5R,5aR)-5-[(1E)-prop-1-enyl]-3-(1H-tetrazol-5...) Show SMILES CC=C[C@@H]1[C@H]2Cc3c([nH]nc3-c3nnn[nH]3)[C@@H]12 |r,w:1.0| Show InChI InChI=1S/C11H12N6/c1-2-3-5-6-4-7-9(8(5)6)12-13-10(7)11-14-16-17-15-11/h2-3,5-6,8H,4H2,1H3,(H,12,13)(H,14,15,16,17)/t5-,6-,8+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	276	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by HTRF assay				Bioorg Med Chem Lett 20: 2797-800 (2010) Article DOI: 10.1016/j.bmcl.2010.03.062 BindingDB Entry DOI: 10.7270/Q2X0676V
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50318903 ((4aR,5S,5aS)-5-allyl-3-(1H-tetrazol-5-yl)-4,4a,5,5...) Show SMILES C=CC[C@H]1[C@H]2Cc3c([nH]nc3-c3nnn[nH]3)[C@@H]12 |r| Show InChI InChI=1S/C11H12N6/c1-2-3-5-6-4-7-9(8(5)6)12-13-10(7)11-14-16-17-15-11/h2,5-6,8H,1,3-4H2,(H,12,13)(H,14,15,16,17)/t5-,6+,8-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.29E+4	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by HTRF assay				Bioorg Med Chem Lett 20: 2797-800 (2010) Article DOI: 10.1016/j.bmcl.2010.03.062 BindingDB Entry DOI: 10.7270/Q2X0676V
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50318888 ((5R,5aS)-5-isobutyl-3-(1H-tetrazol-5-yl)-4,4a,5,5a...) Show SMILES CC(C)C[C@@H]1[C@H]2Cc3c(n[nH]c3[C@@H]12)-c1nnn[nH]1 |r| Show InChI InChI=1S/C12H16N6/c1-5(2)3-6-7-4-8-10(9(6)7)13-14-11(8)12-15-17-18-16-12/h5-7,9H,3-4H2,1-2H3,(H,13,14)(H,15,16,17,18)/t6-,7-,9+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.45E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by HTRF assay				Bioorg Med Chem Lett 20: 2797-800 (2010) Article DOI: 10.1016/j.bmcl.2010.03.062 BindingDB Entry DOI: 10.7270/Q2X0676V
					More data for this Ligand-Target Pair