Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein tyrosine phosphatase type IVA 3 (Homo sapiens (Human)) | BDBM11318 (1,3,8-trihydroxy-6-methyl-9,10-dihydroanthracene-9...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Bioscience and Biotechnology Curated by ChEMBL | Assay Description Inhibition of PRL3 after 1 hr by DiFMUP assay | Bioorg Med Chem Lett 22: 323-6 (2011) Article DOI: 10.1016/j.bmcl.2011.11.008 BindingDB Entry DOI: 10.7270/Q2K074QM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein tyrosine phosphatase type IVA 3 (Homo sapiens (Human)) | BDBM11318 (1,3,8-trihydroxy-6-methyl-9,10-dihydroanthracene-9...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Bioscience and Biotechnology Curated by ChEMBL | Assay Description Inhibition of PRL-3-mediated cell migration in human DLD1 cells after 15 hrs by crystal violet staining based microscopic assay | Bioorg Med Chem Lett 22: 323-6 (2011) Article DOI: 10.1016/j.bmcl.2011.11.008 BindingDB Entry DOI: 10.7270/Q2K074QM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein tyrosine phosphatase type IVA 3 (Homo sapiens (Human)) | BDBM11318 (1,3,8-trihydroxy-6-methyl-9,10-dihydroanthracene-9...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Bioscience and Biotechnology Curated by ChEMBL | Assay Description Inhibition of PRL-3-mediated cell invasion in human DLD1 cells after 20 hrs using crystal violet staining by Matrigel invasion assay | Bioorg Med Chem Lett 22: 323-6 (2011) Article DOI: 10.1016/j.bmcl.2011.11.008 BindingDB Entry DOI: 10.7270/Q2K074QM | |||||||||||
More data for this Ligand-Target Pair |