Found 60 hits Enz. Inhib. hit(s) with all data for entry = 50034596 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50364972
(CHEMBL1950738)Show InChI InChI=1S/C19H24N4O2/c1-22-19(24)8-6-17(21-22)14-5-7-18(20-13-14)25-16-9-11-23(12-10-16)15-3-2-4-15/h5-8,13,15-16H,2-4,9-12H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50364957
(CHEMBL1950643)Show SMILES O=c1ccc(n[nH]1)-c1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C19H23N3O2/c23-19-9-8-18(20-21-19)14-4-6-16(7-5-14)24-17-10-12-22(13-11-17)15-2-1-3-15/h4-9,15,17H,1-3,10-13H2,(H,21,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50364957
(CHEMBL1950643)Show SMILES O=c1ccc(n[nH]1)-c1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C19H23N3O2/c23-19-9-8-18(20-21-19)14-4-6-16(7-5-14)24-17-10-12-22(13-11-17)15-2-1-3-15/h4-9,15,17H,1-3,10-13H2,(H,21,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50352798
(CHEMBL1823402)Show InChI InChI=1S/C20H25N3O2/c1-22-20(24)10-9-19(21-22)15-5-7-17(8-6-15)25-18-11-13-23(14-12-18)16-3-2-4-16/h5-10,16,18H,2-4,11-14H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50364958
(CHEMBL1950743)Show SMILES CC1(C)CC(=NNC1=O)c1ccc(OC2CCN(CC2)C2CCC2)cc1 |c:4| Show InChI InChI=1S/C21H29N3O2/c1-21(2)14-19(22-23-20(21)25)15-6-8-17(9-7-15)26-18-10-12-24(13-11-18)16-4-3-5-16/h6-9,16,18H,3-5,10-14H2,1-2H3,(H,23,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50352799
(CHEMBL1823403)Show InChI InChI=1S/C21H27N3O2/c1-23-21(25)11-10-20(22-23)16-6-8-18(9-7-16)26-19-12-14-24(15-13-19)17-4-2-3-5-17/h6-11,17,19H,2-5,12-15H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50352798
(CHEMBL1823402)Show InChI InChI=1S/C20H25N3O2/c1-22-20(24)10-9-19(21-22)15-5-7-17(8-6-15)25-18-11-13-23(14-12-18)16-3-2-4-16/h5-10,16,18H,2-4,11-14H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50364968
(CHEMBL1950742)Show SMILES O=C1CCC(=NN1)c1ccc(OC2CCN(CC2)C2CCC2)cc1 |c:4| Show InChI InChI=1S/C19H25N3O2/c23-19-9-8-18(20-21-19)14-4-6-16(7-5-14)24-17-10-12-22(13-11-17)15-2-1-3-15/h4-7,15,17H,1-3,8-13H2,(H,21,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50364961
(CHEMBL1950734)Show SMILES Cc1cc(=O)[nH]nc1-c1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C20H25N3O2/c1-14-13-19(24)21-22-20(14)15-5-7-17(8-6-15)25-18-9-11-23(12-10-18)16-3-2-4-16/h5-8,13,16,18H,2-4,9-12H2,1H3,(H,21,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 4.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50364958
(CHEMBL1950743)Show SMILES CC1(C)CC(=NNC1=O)c1ccc(OC2CCN(CC2)C2CCC2)cc1 |c:4| Show InChI InChI=1S/C21H29N3O2/c1-21(2)14-19(22-23-20(21)25)15-6-8-17(9-7-15)26-18-10-12-24(13-11-18)16-4-3-5-16/h6-9,16,18H,3-5,10-14H2,1-2H3,(H,23,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 4.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50364965
(CHEMBL1950644)Show SMILES O=c1ccc(n[nH]1)-c1ccc(OC2CCN(CC2)C2CCCC2)cc1 Show InChI InChI=1S/C20H25N3O2/c24-20-10-9-19(21-22-20)15-5-7-17(8-6-15)25-18-11-13-23(14-12-18)16-3-1-2-4-16/h5-10,16,18H,1-4,11-14H2,(H,22,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50364960
(CHEMBL1950746)Show SMILES C[C@@H]1CC(=O)NN=C1c1ccc(OC2CCN(CC2)C2CCC2)cc1 |r,c:6| Show InChI InChI=1S/C20H27N3O2/c1-14-13-19(24)21-22-20(14)15-5-7-17(8-6-15)25-18-9-11-23(12-10-18)16-3-2-4-16/h5-8,14,16,18H,2-4,9-13H2,1H3,(H,21,24)/t14-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 5.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50364971
(CHEMBL1950739)Show InChI InChI=1S/C20H26N4O2/c1-23-20(25)9-7-18(22-23)15-6-8-19(21-14-15)26-17-10-12-24(13-11-17)16-4-2-3-5-16/h6-9,14,16-17H,2-5,10-13H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 5.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50352799
(CHEMBL1823403)Show InChI InChI=1S/C21H27N3O2/c1-23-21(25)11-10-20(22-23)16-6-8-18(9-7-16)26-19-12-14-24(15-13-19)17-4-2-3-5-17/h6-11,17,19H,2-5,12-15H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50364961
(CHEMBL1950734)Show SMILES Cc1cc(=O)[nH]nc1-c1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C20H25N3O2/c1-14-13-19(24)21-22-20(14)15-5-7-17(8-6-15)25-18-9-11-23(12-10-18)16-3-2-4-16/h5-8,13,16,18H,2-4,9-12H2,1H3,(H,21,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50364974
(CHEMBL1950736)Show SMILES O=c1ccc(n[nH]1)-c1ccc(OC2CCN(CC2)C2CCC2)nc1 Show InChI InChI=1S/C18H22N4O2/c23-17-6-5-16(20-21-17)13-4-7-18(19-12-13)24-15-8-10-22(11-9-15)14-2-1-3-14/h4-7,12,14-15H,1-3,8-11H2,(H,21,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50364970
(CHEMBL1950740)Show SMILES CC(C)n1nc(ccc1=O)-c1ccc(OC2CCN(CC2)C2CCC2)nc1 Show InChI InChI=1S/C21H28N4O2/c1-15(2)25-21(26)9-7-19(23-25)16-6-8-20(22-14-16)27-18-10-12-24(13-11-18)17-4-3-5-17/h6-9,14-15,17-18H,3-5,10-13H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 6.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50364968
(CHEMBL1950742)Show SMILES O=C1CCC(=NN1)c1ccc(OC2CCN(CC2)C2CCC2)cc1 |c:4| Show InChI InChI=1S/C19H25N3O2/c23-19-9-8-18(20-21-19)14-4-6-16(7-5-14)24-17-10-12-22(13-11-17)15-2-1-3-15/h4-7,15,17H,1-3,8-13H2,(H,21,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 6.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50364965
(CHEMBL1950644)Show SMILES O=c1ccc(n[nH]1)-c1ccc(OC2CCN(CC2)C2CCCC2)cc1 Show InChI InChI=1S/C20H25N3O2/c24-20-10-9-19(21-22-20)15-5-7-17(8-6-15)25-18-11-13-23(14-12-18)16-3-1-2-4-16/h5-10,16,18H,1-4,11-14H2,(H,22,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50364966
(CHEMBL1950745)Show SMILES CC1(C)CC(=NNC1=O)c1ccc(OC2CCN(CC2)C2CCC2)c(F)c1 |c:4| Show InChI InChI=1S/C21H28FN3O2/c1-21(2)13-18(23-24-20(21)26)14-6-7-19(17(22)12-14)27-16-8-10-25(11-9-16)15-4-3-5-15/h6-7,12,15-16H,3-5,8-11,13H2,1-2H3,(H,24,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 7.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50364966
(CHEMBL1950745)Show SMILES CC1(C)CC(=NNC1=O)c1ccc(OC2CCN(CC2)C2CCC2)c(F)c1 |c:4| Show InChI InChI=1S/C21H28FN3O2/c1-21(2)13-18(23-24-20(21)26)14-6-7-19(17(22)12-14)27-16-8-10-25(11-9-16)15-4-3-5-15/h6-7,12,15-16H,3-5,8-11,13H2,1-2H3,(H,24,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 7.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50364959
(CHEMBL1950747)Show SMILES C[C@H]1CC(=O)NN=C1c1ccc(OC2CCN(CC2)C2CCC2)cc1 |r,c:6| Show InChI InChI=1S/C20H27N3O2/c1-14-13-19(24)21-22-20(14)15-5-7-17(8-6-15)25-18-9-11-23(12-10-18)16-3-2-4-16/h5-8,14,16,18H,2-4,9-13H2,1H3,(H,21,24)/t14-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 7.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50364972
(CHEMBL1950738)Show InChI InChI=1S/C19H24N4O2/c1-22-19(24)8-6-17(21-22)14-5-7-18(20-13-14)25-16-9-11-23(12-10-16)15-3-2-4-15/h5-8,13,15-16H,2-4,9-12H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 8.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50364963
(CHEMBL1950646)Show InChI InChI=1S/C19H25N3O2/c1-14(2)22-12-10-17(11-13-22)24-16-6-4-15(5-7-16)18-8-9-19(23)21(3)20-18/h4-9,14,17H,10-13H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 9.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50364970
(CHEMBL1950740)Show SMILES CC(C)n1nc(ccc1=O)-c1ccc(OC2CCN(CC2)C2CCC2)nc1 Show InChI InChI=1S/C21H28N4O2/c1-15(2)25-21(26)9-7-19(23-25)16-6-8-20(22-14-16)27-18-10-12-24(13-11-18)17-4-3-5-17/h6-9,14-15,17-18H,3-5,10-13H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 9.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50364960
(CHEMBL1950746)Show SMILES C[C@@H]1CC(=O)NN=C1c1ccc(OC2CCN(CC2)C2CCC2)cc1 |r,c:6| Show InChI InChI=1S/C20H27N3O2/c1-14-13-19(24)21-22-20(14)15-5-7-17(8-6-15)25-18-9-11-23(12-10-18)16-3-2-4-16/h5-8,14,16,18H,2-4,9-13H2,1H3,(H,21,24)/t14-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 9.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50364962
(CHEMBL1950733)Show SMILES O=c1ccc(nn1-c1ccccn1)-c1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C24H26N4O2/c29-24-12-11-22(26-28(24)23-6-1-2-15-25-23)18-7-9-20(10-8-18)30-21-13-16-27(17-14-21)19-4-3-5-19/h1-2,6-12,15,19,21H,3-5,13-14,16-17H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 9.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50364967
(CHEMBL1950744)Show SMILES CC1(C)CC(=NNC1=O)c1ccc(OC2CCN(CC2)C2CCC2)nc1 |c:4| Show InChI InChI=1S/C20H28N4O2/c1-20(2)12-17(22-23-19(20)25)14-6-7-18(21-13-14)26-16-8-10-24(11-9-16)15-4-3-5-15/h6-7,13,15-16H,3-5,8-12H2,1-2H3,(H,23,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50364971
(CHEMBL1950739)Show InChI InChI=1S/C20H26N4O2/c1-23-20(25)9-7-18(22-23)15-6-8-19(21-14-15)26-17-10-12-24(13-11-17)16-4-2-3-5-16/h6-9,14,16-17H,2-5,10-13H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50364959
(CHEMBL1950747)Show SMILES C[C@H]1CC(=O)NN=C1c1ccc(OC2CCN(CC2)C2CCC2)cc1 |r,c:6| Show InChI InChI=1S/C20H27N3O2/c1-14-13-19(24)21-22-20(14)15-5-7-17(8-6-15)25-18-9-11-23(12-10-18)16-3-2-4-16/h5-8,14,16,18H,2-4,9-13H2,1H3,(H,21,24)/t14-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50364962
(CHEMBL1950733)Show SMILES O=c1ccc(nn1-c1ccccn1)-c1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C24H26N4O2/c29-24-12-11-22(26-28(24)23-6-1-2-15-25-23)18-7-9-20(10-8-18)30-21-13-16-27(17-14-21)19-4-3-5-19/h1-2,6-12,15,19,21H,3-5,13-14,16-17H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50364975
(CHEMBL1950735)Show InChI InChI=1S/C17H22N4O2/c1-12(2)21-9-7-14(8-10-21)23-17-6-3-13(11-18-17)15-4-5-16(22)20-19-15/h3-6,11-12,14H,7-10H2,1-2H3,(H,20,22) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50364974
(CHEMBL1950736)Show SMILES O=c1ccc(n[nH]1)-c1ccc(OC2CCN(CC2)C2CCC2)nc1 Show InChI InChI=1S/C18H22N4O2/c23-17-6-5-16(20-21-17)13-4-7-18(19-12-13)24-15-8-10-22(11-9-15)14-2-1-3-14/h4-7,12,14-15H,1-3,8-11H2,(H,21,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50364973
(CHEMBL1950737)Show SMILES O=c1ccc(n[nH]1)-c1ccc(OC2CCN(CC2)C2CCCC2)nc1 Show InChI InChI=1S/C19H24N4O2/c24-18-7-6-17(21-22-18)14-5-8-19(20-13-14)25-16-9-11-23(12-10-16)15-3-1-2-4-15/h5-8,13,15-16H,1-4,9-12H2,(H,22,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50364967
(CHEMBL1950744)Show SMILES CC1(C)CC(=NNC1=O)c1ccc(OC2CCN(CC2)C2CCC2)nc1 |c:4| Show InChI InChI=1S/C20H28N4O2/c1-20(2)12-17(22-23-19(20)25)14-6-7-18(21-13-14)26-16-8-10-24(11-9-16)15-4-3-5-15/h6-7,13,15-16H,3-5,8-12H2,1-2H3,(H,23,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50364969
(CHEMBL1950741)Show SMILES O=c1ccc(nn1-c1ccccn1)-c1ccc(OC2CCN(CC2)C2CCC2)nc1 Show InChI InChI=1S/C23H25N5O2/c29-23-10-8-20(26-28(23)21-6-1-2-13-24-21)17-7-9-22(25-16-17)30-19-11-14-27(15-12-19)18-4-3-5-18/h1-2,6-10,13,16,18-19H,3-5,11-12,14-15H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50364963
(CHEMBL1950646)Show InChI InChI=1S/C19H25N3O2/c1-14(2)22-12-10-17(11-13-22)24-16-6-4-15(5-7-16)18-8-9-19(23)21(3)20-18/h4-9,14,17H,10-13H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 46 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50364973
(CHEMBL1950737)Show SMILES O=c1ccc(n[nH]1)-c1ccc(OC2CCN(CC2)C2CCCC2)nc1 Show InChI InChI=1S/C19H24N4O2/c24-18-7-6-17(21-22-18)14-5-8-19(20-13-14)25-16-9-11-23(12-10-16)15-3-1-2-4-15/h5-8,13,15-16H,1-4,9-12H2,(H,22,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50364969
(CHEMBL1950741)Show SMILES O=c1ccc(nn1-c1ccccn1)-c1ccc(OC2CCN(CC2)C2CCC2)nc1 Show InChI InChI=1S/C23H25N5O2/c29-23-10-8-20(26-28(23)21-6-1-2-13-24-21)17-7-9-22(25-16-17)30-19-11-14-27(15-12-19)18-4-3-5-18/h1-2,6-10,13,16,18-19H,3-5,11-12,14-15H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 82 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50364975
(CHEMBL1950735)Show InChI InChI=1S/C17H22N4O2/c1-12(2)21-9-7-14(8-10-21)23-17-6-3-13(11-18-17)15-4-5-16(22)20-19-15/h3-6,11-12,14H,7-10H2,1-2H3,(H,20,22) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 101 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50364964
(CHEMBL1950645)Show InChI InChI=1S/C16H19N3O2/c1-19-16(20)7-6-15(18-19)12-2-4-13(5-3-12)21-14-8-10-17-11-9-14/h2-7,14,17H,8-11H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 695 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50364964
(CHEMBL1950645)Show InChI InChI=1S/C16H19N3O2/c1-19-16(20)7-6-15(18-19)12-2-4-13(5-3-12)21-14-8-10-17-11-9-14/h2-7,14,17H,8-11H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50364957
(CHEMBL1950643)Show SMILES O=c1ccc(n[nH]1)-c1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C19H23N3O2/c23-19-9-8-18(20-21-19)14-4-6-16(7-5-14)24-17-10-12-22(13-11-17)15-2-1-3-15/h4-9,15,17H,1-3,10-13H2,(H,21,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human Erg by patch clamp assay |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50364974
(CHEMBL1950736)Show SMILES O=c1ccc(n[nH]1)-c1ccc(OC2CCN(CC2)C2CCC2)nc1 Show InChI InChI=1S/C18H22N4O2/c23-17-6-5-16(20-21-17)13-4-7-18(19-12-13)24-15-8-10-22(11-9-15)14-2-1-3-14/h4-7,12,14-15H,1-3,8-11H2,(H,21,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human Erg by patch clamp assay |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50364958
(CHEMBL1950743)Show SMILES CC1(C)CC(=NNC1=O)c1ccc(OC2CCN(CC2)C2CCC2)cc1 |c:4| Show InChI InChI=1S/C21H29N3O2/c1-21(2)14-19(22-23-20(21)25)15-6-8-17(9-7-15)26-18-10-12-24(13-11-18)16-4-3-5-16/h6-9,16,18H,3-5,10-14H2,1-2H3,(H,23,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human Erg by patch clamp assay |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50364959
(CHEMBL1950747)Show SMILES C[C@H]1CC(=O)NN=C1c1ccc(OC2CCN(CC2)C2CCC2)cc1 |r,c:6| Show InChI InChI=1S/C20H27N3O2/c1-14-13-19(24)21-22-20(14)15-5-7-17(8-6-15)25-18-9-11-23(12-10-18)16-3-2-4-16/h5-8,14,16,18H,2-4,9-13H2,1H3,(H,21,24)/t14-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human Erg by patch clamp assay |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50364958
(CHEMBL1950743)Show SMILES CC1(C)CC(=NNC1=O)c1ccc(OC2CCN(CC2)C2CCC2)cc1 |c:4| Show InChI InChI=1S/C21H29N3O2/c1-21(2)14-19(22-23-20(21)25)15-6-8-17(9-7-15)26-18-10-12-24(13-11-18)16-4-3-5-16/h6-9,16,18H,3-5,10-14H2,1-2H3,(H,23,25) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Inhibition of CYP2D6 |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Cytochrome P450 2C19
(Homo sapiens (Human)) | BDBM50364957
(CHEMBL1950643)Show SMILES O=c1ccc(n[nH]1)-c1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C19H23N3O2/c23-19-9-8-18(20-21-19)14-4-6-16(7-5-14)24-17-10-12-22(13-11-17)15-2-1-3-15/h4-9,15,17H,1-3,10-13H2,(H,21,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Inhibition of CYP2C19 |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Cytochrome P450 2C19
(Homo sapiens (Human)) | BDBM50364958
(CHEMBL1950743)Show SMILES CC1(C)CC(=NNC1=O)c1ccc(OC2CCN(CC2)C2CCC2)cc1 |c:4| Show InChI InChI=1S/C21H29N3O2/c1-21(2)14-19(22-23-20(21)25)15-6-8-17(9-7-15)26-18-10-12-24(13-11-18)16-4-3-5-16/h6-9,16,18H,3-5,10-14H2,1-2H3,(H,23,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Inhibition of CYP2C19 |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |
Cytochrome P450 2C9
(Homo sapiens (Human)) | BDBM50364957
(CHEMBL1950643)Show SMILES O=c1ccc(n[nH]1)-c1ccc(OC2CCN(CC2)C2CCC2)cc1 Show InChI InChI=1S/C19H23N3O2/c23-19-9-8-18(20-21-19)14-4-6-16(7-5-14)24-17-10-12-22(13-11-17)15-2-1-3-15/h4-9,15,17H,1-3,10-13H2,(H,21,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Inhibition of CYP2C9 |
Bioorg Med Chem Lett 22: 1504-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.026 BindingDB Entry DOI: 10.7270/Q2W37WSF |
More data for this Ligand-Target Pair | |