Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Steryl-sulfatase (Homo sapiens (Human)) | BDBM50134329 (CHEMBL122708 | Sulfamic acid (11R,12S,15S,16S)-13-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PubMed | 470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Forschungsinstitut Curated by ChEMBL | Assay Description Inhibitory constant against human steroid sulfatase in CHO cells | Bioorg Med Chem Lett 13: 4313-6 (2003) BindingDB Entry DOI: 10.7270/Q28S4QGH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steryl-sulfatase (Homo sapiens (Human)) | BDBM50136297 (CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Forschungsinstitut Curated by ChEMBL | Assay Description Inhibitory constant against human steroid sulfatase in CHO cells | Bioorg Med Chem Lett 13: 4313-6 (2003) BindingDB Entry DOI: 10.7270/Q28S4QGH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steryl-sulfatase (Homo sapiens (Human)) | BDBM50136297 (CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Forschungsinstitut Curated by ChEMBL | Assay Description Inhibitory activity against human steroid sulfatase in sebocytes | Bioorg Med Chem Lett 13: 4313-6 (2003) BindingDB Entry DOI: 10.7270/Q28S4QGH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steryl-sulfatase (Homo sapiens (Human)) | BDBM50136297 (CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.75 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Forschungsinstitut Curated by ChEMBL | Assay Description Inhibitory activity against human steroid sulfatase expressing in CHO cells | Bioorg Med Chem Lett 13: 4313-6 (2003) BindingDB Entry DOI: 10.7270/Q28S4QGH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steryl-sulfatase (Homo sapiens (Human)) | BDBM50136297 (CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.770 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Forschungsinstitut Curated by ChEMBL | Assay Description Inhibition of human STS in keratinocytes | Bioorg Med Chem Lett 13: 4313-6 (2003) BindingDB Entry DOI: 10.7270/Q28S4QGH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steryl-sulfatase (Homo sapiens (Human)) | BDBM50136297 (CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Forschungsinstitut Curated by ChEMBL | Assay Description Inhibitory activity against STS in human MCF-7 breast cancer cells | Bioorg Med Chem Lett 13: 4313-6 (2003) BindingDB Entry DOI: 10.7270/Q28S4QGH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steryl-sulfatase (Homo sapiens (Human)) | BDBM50136297 (CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Forschungsinstitut Curated by ChEMBL | Assay Description Inhibitory constant against human steroid sulfatase in CHO cells | Bioorg Med Chem Lett 13: 4313-6 (2003) BindingDB Entry DOI: 10.7270/Q28S4QGH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor beta (Homo sapiens (Human)) | BDBM50136297 (CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Novartis Forschungsinstitut Curated by ChEMBL | Assay Description Affinity for human estrogen receptor beta | Bioorg Med Chem Lett 13: 4313-6 (2003) BindingDB Entry DOI: 10.7270/Q28S4QGH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor beta (Homo sapiens (Human)) | BDBM50134329 (CHEMBL122708 | Sulfamic acid (11R,12S,15S,16S)-13-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a |
Novartis Forschungsinstitut Curated by ChEMBL | Assay Description Affinity for human estrogen receptor beta | Bioorg Med Chem Lett 13: 4313-6 (2003) BindingDB Entry DOI: 10.7270/Q28S4QGH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50136297 (CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidene...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Novartis Forschungsinstitut Curated by ChEMBL | Assay Description Affinity for human estrogen receptor alpha | Bioorg Med Chem Lett 13: 4313-6 (2003) BindingDB Entry DOI: 10.7270/Q28S4QGH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50134329 (CHEMBL122708 | Sulfamic acid (11R,12S,15S,16S)-13-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a |
Novartis Forschungsinstitut Curated by ChEMBL | Assay Description Affinity for human estrogen receptor alpha | Bioorg Med Chem Lett 13: 4313-6 (2003) BindingDB Entry DOI: 10.7270/Q28S4QGH | |||||||||||
More data for this Ligand-Target Pair |