Found 192 hits Enz. Inhib. hit(s) with all data for entry = 50035442 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50141777
(2,6-Dimethyl-4-phenyl-1-[2-(4-sulfamoyl-phenyl)-et...)Show SMILES Cc1cc(cc(C)[n+]1CCc1ccc(cc1)S(N)(=O)=O)-c1ccccc1 Show InChI InChI=1S/C21H23N2O2S/c1-16-14-20(19-6-4-3-5-7-19)15-17(2)23(16)13-12-18-8-10-21(11-9-18)26(22,24)25/h3-11,14-15H,12-13H2,1-2H3,(H2,22,24,25)/q+1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase IX |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50141792
(2,3,4,6-Tetramethyl-1-[2-(4-sulfamoyl-phenyl)-ethy...)Show SMILES Cc1cc(C)[n+](CCc2ccc(cc2)S(N)(=O)=O)c(C)c1C Show InChI InChI=1S/C17H23N2O2S/c1-12-11-13(2)19(15(4)14(12)3)10-9-16-5-7-17(8-6-16)22(18,20)21/h5-8,11H,9-10H2,1-4H3,(H2,18,20,21)/q+1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase IX |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50141775
(2,6-Diethyl-4-phenyl-1-[2-(4-sulfamoyl-phenyl)-eth...)Show SMILES CCc1cc(cc(CC)[n+]1CCc1ccc(cc1)S(N)(=O)=O)-c1ccccc1 Show InChI InChI=1S/C23H27N2O2S/c1-3-21-16-20(19-8-6-5-7-9-19)17-22(4-2)25(21)15-14-18-10-12-23(13-11-18)28(24,26)27/h5-13,16-17H,3-4,14-15H2,1-2H3,(H2,24,26,27)/q+1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase IX |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50141777
(2,6-Dimethyl-4-phenyl-1-[2-(4-sulfamoyl-phenyl)-et...)Show SMILES Cc1cc(cc(C)[n+]1CCc1ccc(cc1)S(N)(=O)=O)-c1ccccc1 Show InChI InChI=1S/C21H23N2O2S/c1-16-14-20(19-6-4-3-5-7-19)15-17(2)23(16)13-12-18-8-10-21(11-9-18)26(22,24)25/h3-11,14-15H,12-13H2,1-2H3,(H2,22,24,25)/q+1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50141775
(2,6-Diethyl-4-phenyl-1-[2-(4-sulfamoyl-phenyl)-eth...)Show SMILES CCc1cc(cc(CC)[n+]1CCc1ccc(cc1)S(N)(=O)=O)-c1ccccc1 Show InChI InChI=1S/C23H27N2O2S/c1-3-21-16-20(19-8-6-5-7-9-19)17-22(4-2)25(21)15-14-18-10-12-23(13-11-18)28(24,26)27/h5-13,16-17H,3-4,14-15H2,1-2H3,(H2,24,26,27)/q+1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50141792
(2,3,4,6-Tetramethyl-1-[2-(4-sulfamoyl-phenyl)-ethy...)Show SMILES Cc1cc(C)[n+](CCc2ccc(cc2)S(N)(=O)=O)c(C)c1C Show InChI InChI=1S/C17H23N2O2S/c1-12-11-13(2)19(15(4)14(12)3)10-9-16-5-7-17(8-6-16)22(18,20)21/h5-8,11H,9-10H2,1-4H3,(H2,18,20,21)/q+1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM10880
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
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| DrugBank MMDB PDB Article PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM11641
(1-N-(4-sulfamoylphenyl-ethyl)-2,4,6-trimethylpyrid...)Show InChI InChI=1S/C16H21N2O2S/c1-12-10-13(2)18(14(3)11-12)9-8-15-4-6-16(7-5-15)21(17,19)20/h4-7,10-11H,8-9H2,1-3H3,(H2,17,19,20)/q+1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase IX |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM10881
(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Show InChI InChI=1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM10890
(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)Show SMILES NS(=O)(=O)c1ccc(cc1)S(=O)(=O)Nc1cccc2c(Cl)c[nH]c12 Show InChI InChI=1S/C14H12ClN3O4S2/c15-12-8-17-14-11(12)2-1-3-13(14)18-24(21,22)10-6-4-9(5-7-10)23(16,19)20/h1-8,17-18H,(H2,16,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50141800
(2-Isopropyl-4,6-dimethyl-1-[2-(4-sulfamoyl-phenyl)...)Show SMILES CC(C)c1cc(C)cc(C)[n+]1CCc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H25N2O2S/c1-13(2)18-12-14(3)11-15(4)20(18)10-9-16-5-7-17(8-6-16)23(19,21)22/h5-8,11-13H,9-10H2,1-4H3,(H2,19,21,22)/q+1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50141807
(2,6-Diisopropyl-4-methyl-1-[2-(4-sulfamoyl-phenyl)...)Show SMILES CC(C)c1cc(C)cc(C(C)C)[n+]1CCc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C20H29N2O2S/c1-14(2)19-12-16(5)13-20(15(3)4)22(19)11-10-17-6-8-18(9-7-17)25(21,23)24/h6-9,12-15H,10-11H2,1-5H3,(H2,21,23,24)/q+1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50141783
(2,6-Dimethyl-4-phenyl-1-(4-sulfamoyl-benzyl)-pyrid...)Show SMILES Cc1cc(cc(C)[n+]1Cc1ccc(cc1)S(N)(=O)=O)-c1ccccc1 Show InChI InChI=1S/C20H21N2O2S/c1-15-12-19(18-6-4-3-5-7-18)13-16(2)22(15)14-17-8-10-20(11-9-17)25(21,23)24/h3-13H,14H2,1-2H3,(H2,21,23,24)/q+1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Bos taurus (bovine)) | BDBM50141777
(2,6-Dimethyl-4-phenyl-1-[2-(4-sulfamoyl-phenyl)-et...)Show SMILES Cc1cc(cc(C)[n+]1CCc1ccc(cc1)S(N)(=O)=O)-c1ccccc1 Show InChI InChI=1S/C21H23N2O2S/c1-16-14-20(19-6-4-3-5-7-19)15-17(2)23(16)13-12-18-8-10-21(11-9-18)26(22,24)25/h3-11,14-15H,12-13H2,1-2H3,(H2,22,24,25)/q+1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against carbonic anhydrase IV from bovine lung microsomes |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Bos taurus (bovine)) | BDBM50141775
(2,6-Diethyl-4-phenyl-1-[2-(4-sulfamoyl-phenyl)-eth...)Show SMILES CCc1cc(cc(CC)[n+]1CCc1ccc(cc1)S(N)(=O)=O)-c1ccccc1 Show InChI InChI=1S/C23H27N2O2S/c1-3-21-16-20(19-8-6-5-7-9-19)17-22(4-2)25(21)15-14-18-10-12-23(13-11-18)28(24,26)27/h5-13,16-17H,3-4,14-15H2,1-2H3,(H2,24,26,27)/q+1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against carbonic anhydrase IV from bovine lung microsomes |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50141798
(2,6-Diisopropyl-4-phenyl-1-[2-(4-sulfamoyl-phenyl)...)Show SMILES CC(C)c1cc(cc(C(C)C)[n+]1CCc1ccc(cc1)S(N)(=O)=O)-c1ccccc1 Show InChI InChI=1S/C25H31N2O2S/c1-18(2)24-16-22(21-8-6-5-7-9-21)17-25(19(3)4)27(24)15-14-20-10-12-23(13-11-20)30(26,28)29/h5-13,16-19H,14-15H2,1-4H3,(H2,26,28,29)/q+1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50141796
(2,6-Diethyl-4-phenyl-1-(4-sulfamoyl-benzyl)-pyridi...)Show SMILES CCc1cc(cc(CC)[n+]1Cc1ccc(cc1)S(N)(=O)=O)-c1ccccc1 Show InChI InChI=1S/C22H25N2O2S/c1-3-20-14-19(18-8-6-5-7-9-18)15-21(4-2)24(20)16-17-10-12-22(13-11-17)27(23,25)26/h5-15H,3-4,16H2,1-2H3,(H2,23,25,26)/q+1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM11641
(1-N-(4-sulfamoylphenyl-ethyl)-2,4,6-trimethylpyrid...)Show InChI InChI=1S/C16H21N2O2S/c1-12-10-13(2)18(14(3)11-12)9-8-15-4-6-16(7-5-15)21(17,19)20/h4-7,10-11H,8-9H2,1-3H3,(H2,17,19,20)/q+1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Carbonic anhydrase 4
(Bos taurus (bovine)) | BDBM50141792
(2,3,4,6-Tetramethyl-1-[2-(4-sulfamoyl-phenyl)-ethy...)Show SMILES Cc1cc(C)[n+](CCc2ccc(cc2)S(N)(=O)=O)c(C)c1C Show InChI InChI=1S/C17H23N2O2S/c1-12-11-13(2)19(15(4)14(12)3)10-9-16-5-7-17(8-6-16)22(18,20)21/h5-8,11H,9-10H2,1-4H3,(H2,18,20,21)/q+1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against carbonic anhydrase IV from bovine lung microsomes |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM10890
(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)Show SMILES NS(=O)(=O)c1ccc(cc1)S(=O)(=O)Nc1cccc2c(Cl)c[nH]c12 Show InChI InChI=1S/C14H12ClN3O4S2/c15-12-8-17-14-11(12)2-1-3-13(14)18-24(21,22)10-6-4-9(5-7-10)23(16,19)20/h1-8,17-18H,(H2,16,19,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase IX |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM10880
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
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Similars
| Article PubMed
| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase IX |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50141783
(2,6-Dimethyl-4-phenyl-1-(4-sulfamoyl-benzyl)-pyrid...)Show SMILES Cc1cc(cc(C)[n+]1Cc1ccc(cc1)S(N)(=O)=O)-c1ccccc1 Show InChI InChI=1S/C20H21N2O2S/c1-15-12-19(18-6-4-3-5-7-18)13-16(2)22(15)14-17-8-10-20(11-9-17)25(21,23)24/h3-13H,14H2,1-2H3,(H2,21,23,24)/q+1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase IX |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM10881
(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Show InChI InChI=1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid PDB UniChem
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Similars
| Article PubMed
| 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase IX |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50141796
(2,6-Diethyl-4-phenyl-1-(4-sulfamoyl-benzyl)-pyridi...)Show SMILES CCc1cc(cc(CC)[n+]1Cc1ccc(cc1)S(N)(=O)=O)-c1ccccc1 Show InChI InChI=1S/C22H25N2O2S/c1-3-20-14-19(18-8-6-5-7-9-18)15-21(4-2)24(20)16-17-10-12-22(13-11-17)27(23,25)26/h5-15H,3-4,16H2,1-2H3,(H2,23,25,26)/q+1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase IX |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM10890
(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)Show SMILES NS(=O)(=O)c1ccc(cc1)S(=O)(=O)Nc1cccc2c(Cl)c[nH]c12 Show InChI InChI=1S/C14H12ClN3O4S2/c15-12-8-17-14-11(12)2-1-3-13(14)18-24(21,22)10-6-4-9(5-7-10)23(16,19)20/h1-8,17-18H,(H2,16,19,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase I |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50141795
(2,3,4,6-Tetramethyl-1-(4-sulfamoyl-benzyl)-pyridin...)Show InChI InChI=1S/C16H21N2O2S/c1-11-9-12(2)18(14(4)13(11)3)10-15-5-7-16(8-6-15)21(17,19)20/h5-9H,10H2,1-4H3,(H2,17,19,20)/q+1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50141800
(2-Isopropyl-4,6-dimethyl-1-[2-(4-sulfamoyl-phenyl)...)Show SMILES CC(C)c1cc(C)cc(C)[n+]1CCc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H25N2O2S/c1-13(2)18-12-14(3)11-15(4)20(18)10-9-16-5-7-17(8-6-16)23(19,21)22/h5-8,11-13H,9-10H2,1-4H3,(H2,19,21,22)/q+1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase IX |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Bos taurus (bovine)) | BDBM50141800
(2-Isopropyl-4,6-dimethyl-1-[2-(4-sulfamoyl-phenyl)...)Show SMILES CC(C)c1cc(C)cc(C)[n+]1CCc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H25N2O2S/c1-13(2)18-12-14(3)11-15(4)20(18)10-9-16-5-7-17(8-6-16)23(19,21)22/h5-8,11-13H,9-10H2,1-4H3,(H2,19,21,22)/q+1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against carbonic anhydrase IV from bovine lung microsomes |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50141795
(2,3,4,6-Tetramethyl-1-(4-sulfamoyl-benzyl)-pyridin...)Show InChI InChI=1S/C16H21N2O2S/c1-11-9-12(2)18(14(4)13(11)3)10-15-5-7-16(8-6-15)21(17,19)20/h5-9H,10H2,1-4H3,(H2,17,19,20)/q+1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase IX |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Bos taurus (bovine)) | BDBM10881
(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Show InChI InChI=1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against carbonic anhydrase IV from bovine lung microsomes |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50141801
(2-Methyl-4,6-diphenyl-1-[2-(4-sulfamoyl-phenyl)-et...)Show SMILES Cc1cc(cc(-c2ccccc2)[n+]1CCc1ccc(cc1)S(N)(=O)=O)-c1ccccc1 Show InChI InChI=1S/C26H25N2O2S/c1-20-18-24(22-8-4-2-5-9-22)19-26(23-10-6-3-7-11-23)28(20)17-16-21-12-14-25(15-13-21)31(27,29)30/h2-15,18-19H,16-17H2,1H3,(H2,27,29,30)/q+1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase IX |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM10883
(4,5-dichlorobenzene-1,3-disulfonamide | CHEMBL17 |...)Show InChI InChI=1S/C6H6Cl2N2O4S2/c7-4-1-3(15(9,11)12)2-5(6(4)8)16(10,13)14/h1-2H,(H2,9,11,12)(H2,10,13,14) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
| DrugBank MMDB PDB Article PubMed
| 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50141773
(2,4,6-Trimethyl-1-(4-sulfamoyl-benzyl)-pyridinium;...)Show InChI InChI=1S/C15H19N2O2S/c1-11-8-12(2)17(13(3)9-11)10-14-4-6-15(7-5-14)20(16,18)19/h4-9H,10H2,1-3H3,(H2,16,18,19)/q+1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase IX |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50141799
(2,3,4,6-Tetramethyl-1-(4-sulfamoyl-phenyl)-pyridin...)Show InChI InChI=1S/C15H19N2O2S/c1-10-9-11(2)17(13(4)12(10)3)14-5-7-15(8-6-14)20(16,18)19/h5-9H,1-4H3,(H2,16,18,19)/q+1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50141765
(2-Isopropyl-4,6-dimethyl-1-(4-sulfamoyl-benzyl)-py...)Show SMILES CC(C)c1cc(C)cc(C)[n+]1Cc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C17H23N2O2S/c1-12(2)17-10-13(3)9-14(4)19(17)11-15-5-7-16(8-6-15)22(18,20)21/h5-10,12H,11H2,1-4H3,(H2,18,20,21)/q+1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 42 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase IX |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50141781
(4-Phenyl-2,6-dipropyl-1-[2-(4-sulfamoyl-phenyl)-et...)Show SMILES CCCc1cc(cc(CCC)[n+]1CCc1ccc(cc1)S(N)(=O)=O)-c1ccccc1 Show InChI InChI=1S/C25H31N2O2S/c1-3-8-23-18-22(21-10-6-5-7-11-21)19-24(9-4-2)27(23)17-16-20-12-14-25(15-13-20)30(26,28)29/h5-7,10-15,18-19H,3-4,8-9,16-17H2,1-2H3,(H2,26,28,29)/q+1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 42 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50141804
(2,6-Diethyl-4-phenyl-1-(4-sulfamoyl-phenyl)-pyridi...)Show SMILES CCc1cc(cc(CC)[n+]1-c1ccc(cc1)S(N)(=O)=O)-c1ccccc1 Show InChI InChI=1S/C21H23N2O2S/c1-3-18-14-17(16-8-6-5-7-9-16)15-19(4-2)23(18)20-10-12-21(13-11-20)26(22,24)25/h5-15H,3-4H2,1-2H3,(H2,22,24,25)/q+1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase IX |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50141779
(2,6-Dimethyl-4-phenyl-1-(4-sulfamoyl-phenyl)-pyrid...)Show SMILES Cc1cc(cc(C)[n+]1-c1ccc(cc1)S(N)(=O)=O)-c1ccccc1 Show InChI InChI=1S/C19H19N2O2S/c1-14-12-17(16-6-4-3-5-7-16)13-15(2)21(14)18-8-10-19(11-9-18)24(20,22)23/h3-13H,1-2H3,(H2,20,22,23)/q+1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase IX |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50141807
(2,6-Diisopropyl-4-methyl-1-[2-(4-sulfamoyl-phenyl)...)Show SMILES CC(C)c1cc(C)cc(C(C)C)[n+]1CCc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C20H29N2O2S/c1-14(2)19-12-16(5)13-20(15(3)4)22(19)11-10-17-6-8-18(9-7-17)25(21,23)24/h6-9,12-15H,10-11H2,1-5H3,(H2,21,23,24)/q+1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 49 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase IX |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50141793
(2,6-Diisopropyl-4-phenyl-1-(4-sulfamoyl-phenyl)-py...)Show SMILES CC(C)c1cc(cc(C(C)C)[n+]1-c1ccc(cc1)S(N)(=O)=O)-c1ccccc1 Show InChI InChI=1S/C23H27N2O2S/c1-16(2)22-14-19(18-8-6-5-7-9-18)15-23(17(3)4)25(22)20-10-12-21(13-11-20)28(24,26)27/h5-17H,1-4H3,(H2,24,26,27)/q+1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM10883
(4,5-dichlorobenzene-1,3-disulfonamide | CHEMBL17 |...)Show InChI InChI=1S/C6H6Cl2N2O4S2/c7-4-1-3(15(9,11)12)2-5(6(4)8)16(10,13)14/h1-2H,(H2,9,11,12)(H2,10,13,14) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
| Article PubMed
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase IX |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50141765
(2-Isopropyl-4,6-dimethyl-1-(4-sulfamoyl-benzyl)-py...)Show SMILES CC(C)c1cc(C)cc(C)[n+]1Cc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C17H23N2O2S/c1-12(2)17-10-13(3)9-14(4)19(17)11-15-5-7-16(8-6-15)22(18,20)21/h5-10,12H,11H2,1-4H3,(H2,18,20,21)/q+1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50141773
(2,4,6-Trimethyl-1-(4-sulfamoyl-benzyl)-pyridinium;...)Show InChI InChI=1S/C15H19N2O2S/c1-11-8-12(2)17(13(3)9-11)10-14-4-6-15(7-5-14)20(16,18)19/h4-9H,10H2,1-3H3,(H2,16,18,19)/q+1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM10881
(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Show InChI InChI=1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase I |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Carbonic anhydrase 4
(Bos taurus (bovine)) | BDBM50141795
(2,3,4,6-Tetramethyl-1-(4-sulfamoyl-benzyl)-pyridin...)Show InChI InChI=1S/C16H21N2O2S/c1-11-9-12(2)18(14(4)13(11)3)10-15-5-7-16(8-6-15)21(17,19)20/h5-9H,10H2,1-4H3,(H2,17,19,20)/q+1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against carbonic anhydrase IV from bovine lung microsomes |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Bos taurus (bovine)) | BDBM50141796
(2,6-Diethyl-4-phenyl-1-(4-sulfamoyl-benzyl)-pyridi...)Show SMILES CCc1cc(cc(CC)[n+]1Cc1ccc(cc1)S(N)(=O)=O)-c1ccccc1 Show InChI InChI=1S/C22H25N2O2S/c1-3-20-14-19(18-8-6-5-7-9-18)15-21(4-2)24(20)16-17-10-12-22(13-11-17)27(23,25)26/h5-15H,3-4,16H2,1-2H3,(H2,23,25,26)/q+1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 52 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against carbonic anhydrase IV from bovine lung microsomes |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50141766
(2,6-Diisopropyl-4-methyl-1-(4-sulfamoyl-benzyl)-py...)Show SMILES CC(C)c1cc(C)cc(C(C)C)[n+]1Cc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C19H27N2O2S/c1-13(2)18-10-15(5)11-19(14(3)4)21(18)12-16-6-8-17(9-7-16)24(20,22)23/h6-11,13-14H,12H2,1-5H3,(H2,20,22,23)/q+1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 54 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase IX |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50141804
(2,6-Diethyl-4-phenyl-1-(4-sulfamoyl-phenyl)-pyridi...)Show SMILES CCc1cc(cc(CC)[n+]1-c1ccc(cc1)S(N)(=O)=O)-c1ccccc1 Show InChI InChI=1S/C21H23N2O2S/c1-3-18-14-17(16-8-6-5-7-9-16)15-19(4-2)23(18)20-10-12-21(13-11-20)26(22,24)25/h5-15H,3-4H2,1-2H3,(H2,22,24,25)/q+1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50141779
(2,6-Dimethyl-4-phenyl-1-(4-sulfamoyl-phenyl)-pyrid...)Show SMILES Cc1cc(cc(C)[n+]1-c1ccc(cc1)S(N)(=O)=O)-c1ccccc1 Show InChI InChI=1S/C19H19N2O2S/c1-14-12-17(16-6-4-3-5-7-16)13-15(2)21(14)18-8-10-19(11-9-18)24(20,22)23/h3-13H,1-2H3,(H2,20,22,23)/q+1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Bos taurus (bovine)) | BDBM11641
(1-N-(4-sulfamoylphenyl-ethyl)-2,4,6-trimethylpyrid...)Show InChI InChI=1S/C16H21N2O2S/c1-12-10-13(2)18(14(3)11-12)9-8-15-4-6-16(7-5-15)21(17,19)20/h4-7,10-11H,8-9H2,1-3H3,(H2,17,19,20)/q+1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Slovak Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibitory activity against carbonic anhydrase IV from bovine lung microsomes |
Bioorg Med Chem Lett 14: 869-73 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.029 BindingDB Entry DOI: 10.7270/Q24M953W |
More data for this Ligand-Target Pair | |