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Compile Data Set for Download or QSAR

Found 139 hits Enz. Inhib. hit(s) with all data for entry = 50035991   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholecystokinin receptor type A


(RAT)		BDBM21147
PNG
((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...)
Show SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccc(OS(O)(=O)=O)cc1)NC(=O)[C@@H](N)CC(O)=O)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C49H62N10O16S3/c1-76-18-16-34(55-47(69)37(58-44(66)32(50)23-41(61)62)21-28-12-14-30(15-13-28)75-78(72,73)74)45(67)53-26-40(60)54-38(22-29-25-52-33-11-7-6-10-31(29)33)48(70)56-35(17-19-77-2)46(68)59-39(24-42(63)64)49(71)57-36(43(51)65)20-27-8-4-3-5-9-27/h3-15,25,32,34-39,52H,16-24,26,50H2,1-2H3,(H2,51,65)(H,53,67)(H,54,60)(H,55,69)(H,56,70)(H,57,71)(H,58,66)(H,59,68)(H,61,62)(H,63,64)(H,72,73,74)/t32-,34-,35-,36-,37-,38-,39-/m0/s1
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n/an/a 0.5n/an/an/an/an/an/a



Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Concentration required to inhibit by 50% specific binding of [125I](BH)-CCK-8 to cholecystokinin type A receptor in rat pancreatic acini

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM21147
PNG
((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...)
Show SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccc(OS(O)(=O)=O)cc1)NC(=O)[C@@H](N)CC(O)=O)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C49H62N10O16S3/c1-76-18-16-34(55-47(69)37(58-44(66)32(50)23-41(61)62)21-28-12-14-30(15-13-28)75-78(72,73)74)45(67)53-26-40(60)54-38(22-29-25-52-33-11-7-6-10-31(29)33)48(70)56-35(17-19-77-2)46(68)59-39(24-42(63)64)49(71)57-36(43(51)65)20-27-8-4-3-5-9-27/h3-15,25,32,34-39,52H,16-24,26,50H2,1-2H3,(H2,51,65)(H,53,67)(H,54,60)(H,55,69)(H,56,70)(H,57,71)(H,58,66)(H,59,68)(H,61,62)(H,63,64)(H,72,73,74)/t32-,34-,35-,36-,37-,38-,39-/m0/s1
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Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50024321
PNG
(3-{2-[2-(3-tert-Butoxycarbonylamino-propionylamino...)
Show SMILES CSCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CCNC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C37H49N7O9S/c1-37(2,3)53-36(52)39-16-14-30(45)41-28(19-23-21-40-25-13-9-8-12-24(23)25)34(50)42-26(15-17-54-4)33(49)44-29(20-31(46)47)35(51)43-27(32(38)48)18-22-10-6-5-7-11-22/h5-13,21,26-29,40H,14-20H2,1-4H3,(H2,38,48)(H,39,52)(H,41,45)(H,42,50)(H,43,51)(H,44,49)(H,46,47)/t26-,27-,28-,29-/m0/s1
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Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Cholecystokinin receptor type A


(RAT)		BDBM50008185
PNG
(4-Dipentylcarbamoyl-4-[(naphthalene-2-carbonyl)-am...)
Show SMILES CCCCCN(CCCCC)C(=O)C(CCC(O)=O)NC(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C26H36N2O4/c1-3-5-9-17-28(18-10-6-4-2)26(32)23(15-16-24(29)30)27-25(31)22-14-13-20-11-7-8-12-21(20)19-22/h7-8,11-14,19,23H,3-6,9-10,15-18H2,1-2H3,(H,27,31)(H,29,30)
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Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Concentration required to inhibit by 50% specific binding of [125I](BH)-CCK-8 to cholecystokinin type A receptor in rat pancreatic acini

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Cholecystokinin receptor type A


(RAT)		BDBM50008170
PNG
(4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-...)
Show SMILES CCCCCN(CCCCC)C(=O)C(CCC(O)=O)NC(=O)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C22H32Cl2N2O4/c1-3-5-7-13-26(14-8-6-4-2)22(30)19(11-12-20(27)28)25-21(29)16-9-10-17(23)18(24)15-16/h9-10,15,19H,3-8,11-14H2,1-2H3,(H,25,29)(H,27,28)
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Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Concentration required to inhibit by 50% specific binding of [125I](BH)-CCK-8 to cholecystokinin type A receptor in rat pancreatic acini

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Cholecystokinin receptor type A


(RAT)		BDBM50008203
PNG
(4-(3,5-Dichloro-benzoylamino)-4-dipentylcarbamoyl-...)
Show SMILES CCCCCN(CCCCC)C(=O)C(CCC(O)=O)NC(=O)c1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C22H32Cl2N2O4/c1-3-5-7-11-26(12-8-6-4-2)22(30)19(9-10-20(27)28)25-21(29)16-13-17(23)15-18(24)14-16/h13-15,19H,3-12H2,1-2H3,(H,25,29)(H,27,28)
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Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Concentration required to inhibit by 50% specific binding of [125I](BH)-CCK-8 to cholecystokinin type A receptor in rat pancreatic acini

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(Homo sapiens (Human))		BDBM50008172
PNG
(4-(8-Aza-spiro[4.5]dec-8-ylcarbamoyl)-4-(3,5-dichl...)
Show SMILES OC(=O)CCC(NC(=O)c1cc(Cl)cc(Cl)c1)C(=O)NN1CCC2(CCCC2)CC1
Show InChI InChI=1S/C21H27Cl2N3O4/c22-15-11-14(12-16(23)13-15)19(29)24-17(3-4-18(27)28)20(30)25-26-9-7-21(8-10-26)5-1-2-6-21/h11-13,17H,1-10H2,(H,24,29)(H,25,30)(H,27,28)
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Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Concentration required to inhibit by 50% the specific binding of [3H]pentagastrin to CCK-B in rabbit gastric gland

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008180
PNG
(4-(3-Aza-spiro[5.5]undec-3-ylcarbamoyl)-4-[(naphth...)
Show SMILES OC(=O)CCC(NC(=O)c1ccc2ccccc2c1)C(=O)NN1CCC2(CCCCC2)CC1
Show InChI InChI=1S/C26H33N3O4/c30-23(31)11-10-22(27-24(32)21-9-8-19-6-2-3-7-20(19)18-21)25(33)28-29-16-14-26(15-17-29)12-4-1-5-13-26/h2-3,6-9,18,22H,1,4-5,10-17H2,(H,27,32)(H,28,33)(H,30,31)
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Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008163
PNG
(4-(2-Adamantan-1-yl-ethylcarbamoyl)-4-(3,5-dichlor...)
Show SMILES OC(=O)CCC(NC(=O)c1cc(Cl)cc(Cl)c1)C(=O)NCCC12CC3CC(CC(C3)C1)C2 |TLB:25:26:30:24.23.29,THB:25:24:30:26.31.27,27:28:23:26.31.25,27:26:23:28.30.29|
Show InChI InChI=1S/C24H30Cl2N2O4/c25-18-8-17(9-19(26)10-18)22(31)28-20(1-2-21(29)30)23(32)27-4-3-24-11-14-5-15(12-24)7-16(6-14)13-24/h8-10,14-16,20H,1-7,11-13H2,(H,27,32)(H,28,31)(H,29,30)
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Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Cholecystokinin receptor type A


(RAT)		BDBM50008178
PNG
(4-(4,4-Dimethyl-pentylcarbamoyl)-4-[(quinoline-3-c...)
Show SMILES CC(C)(C)CCCNC(=O)C(CCC(O)=O)NC(=O)c1cnc2ccccc2c1
Show InChI InChI=1S/C22H29N3O4/c1-22(2,3)11-6-12-23-21(29)18(9-10-19(26)27)25-20(28)16-13-15-7-4-5-8-17(15)24-14-16/h4-5,7-8,13-14,18H,6,9-12H2,1-3H3,(H,23,29)(H,25,28)(H,26,27)
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Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Concentration required to inhibit by 50% specific binding of [125I](BH)-CCK-8 to cholecystokinin type A receptor in rat pancreatic acini

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008211
PNG
(4-(8-Aza-spiro[4.5]dec-8-ylcarbamoyl)-4-[(naphthal...)
Show SMILES OC(=O)CCC(NC(=O)c1ccc2ccccc2c1)C(=O)NN1CCC2(CCCC2)CC1
Show InChI InChI=1S/C25H31N3O4/c29-22(30)10-9-21(24(32)27-28-15-13-25(14-16-28)11-3-4-12-25)26-23(31)20-8-7-18-5-1-2-6-19(18)17-20/h1-2,5-8,17,21H,3-4,9-16H2,(H,26,31)(H,27,32)(H,29,30)
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Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Cholecystokinin receptor type A


(RAT)		BDBM50008177
PNG
(4-(3-Aza-spiro[5.5]undec-3-ylcarbamoyl)-4-(3,4-dic...)
Show SMILES OC(=O)CCC(NC(=O)c1ccc(Cl)c(Cl)c1)C(=O)NN1CCC2(CCCCC2)CC1
Show InChI InChI=1S/C22H29Cl2N3O4/c23-16-5-4-15(14-17(16)24)20(30)25-18(6-7-19(28)29)21(31)26-27-12-10-22(11-13-27)8-2-1-3-9-22/h4-5,14,18H,1-3,6-13H2,(H,25,30)(H,26,31)(H,28,29)
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Curated by ChEMBL


Assay Description
Concentration required to inhibit by 50% specific binding of [125I](BH)-CCK-8 to cholecystokinin type A receptor in rat pancreatic acini

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Cholecystokinin receptor type A


(RAT)		BDBM50008207
PNG
(4-(3-Aza-spiro[5.5]undec-3-ylcarbamoyl)-4-[(quinol...)
Show SMILES OC(=O)CCC(NC(=O)c1cnc2ccccc2c1)C(=O)NN1CCC2(CCCCC2)CC1
Show InChI InChI=1S/C25H32N4O4/c30-22(31)9-8-21(27-23(32)19-16-18-6-2-3-7-20(18)26-17-19)24(33)28-29-14-12-25(13-15-29)10-4-1-5-11-25/h2-3,6-7,16-17,21H,1,4-5,8-15H2,(H,27,32)(H,28,33)(H,30,31)
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Curated by ChEMBL


Assay Description
Concentration required to inhibit by 50% specific binding of [125I](BH)-CCK-8 to cholecystokinin type A receptor in rat pancreatic acini

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008190
PNG
(4-(2-Adamantan-1-yl-ethylcarbamoyl)-4-(3-chloro-be...)
Show SMILES OC(=O)CCC(NC(=O)c1cccc(Cl)c1)C(=O)NCCC12CC3CC(CC(C3)C1)C2 |TLB:28:27:30:23.22.24,28:23:30:27.29.26,24:25:29:23.22.28,THB:24:23:29:25.30.26|
Show InChI InChI=1S/C24H31ClN2O4/c25-19-3-1-2-18(11-19)22(30)27-20(4-5-21(28)29)23(31)26-7-6-24-12-15-8-16(13-24)10-17(9-15)14-24/h1-3,11,15-17,20H,4-10,12-14H2,(H,26,31)(H,27,30)(H,28,29)
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Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008177
PNG
(4-(3-Aza-spiro[5.5]undec-3-ylcarbamoyl)-4-(3,4-dic...)
Show SMILES OC(=O)CCC(NC(=O)c1ccc(Cl)c(Cl)c1)C(=O)NN1CCC2(CCCCC2)CC1
Show InChI InChI=1S/C22H29Cl2N3O4/c23-16-5-4-15(14-17(16)24)20(30)25-18(6-7-19(28)29)21(31)26-27-12-10-22(11-13-27)8-2-1-3-9-22/h4-5,14,18H,1-3,6-13H2,(H,25,30)(H,26,31)(H,28,29)
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Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008218
PNG
(4-(8-Aza-spiro[4.5]dec-8-ylcarbamoyl)-4-[(1H-indol...)
Show SMILES OC(=O)CCC(NC(=O)c1cc2ccccc2[nH]1)C(=O)NN1CCC2(CCCC2)CC1
Show InChI InChI=1S/C23H30N4O4/c28-20(29)8-7-18(25-21(30)19-15-16-5-1-2-6-17(16)24-19)22(31)26-27-13-11-23(12-14-27)9-3-4-10-23/h1-2,5-6,15,18,24H,3-4,7-14H2,(H,25,30)(H,26,31)(H,28,29)
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Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008198
PNG
(4-(8-Aza-spiro[4.5]dec-8-ylcarbamoyl)-4-(3,4-dichl...)
Show SMILES OC(=O)CCC(NC(=O)c1ccc(Cl)c(Cl)c1)C(=O)NN1CCC2(CCCC2)CC1
Show InChI InChI=1S/C21H27Cl2N3O4/c22-15-4-3-14(13-16(15)23)19(29)24-17(5-6-18(27)28)20(30)25-26-11-9-21(10-12-26)7-1-2-8-21/h3-4,13,17H,1-2,5-12H2,(H,24,29)(H,25,30)(H,27,28)
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Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008185
PNG
(4-Dipentylcarbamoyl-4-[(naphthalene-2-carbonyl)-am...)
Show SMILES CCCCCN(CCCCC)C(=O)C(CCC(O)=O)NC(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C26H36N2O4/c1-3-5-9-17-28(18-10-6-4-2)26(32)23(15-16-24(29)30)27-25(31)22-14-13-20-11-7-8-12-21(20)19-22/h7-8,11-14,19,23H,3-6,9-10,15-18H2,1-2H3,(H,27,31)(H,29,30)
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Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Cholecystokinin receptor type A


(RAT)		BDBM50008180
PNG
(4-(3-Aza-spiro[5.5]undec-3-ylcarbamoyl)-4-[(naphth...)
Show SMILES OC(=O)CCC(NC(=O)c1ccc2ccccc2c1)C(=O)NN1CCC2(CCCCC2)CC1
Show InChI InChI=1S/C26H33N3O4/c30-23(31)11-10-22(27-24(32)21-9-8-19-6-2-3-7-20(19)18-21)25(33)28-29-16-14-26(15-17-29)12-4-1-5-13-26/h2-3,6-9,18,22H,1,4-5,10-17H2,(H,27,32)(H,28,33)(H,30,31)
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Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Concentration required to inhibit by 50% specific binding of [125I](BH)-CCK-8 to cholecystokinin type A receptor in rat pancreatic acini

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008172
PNG
(4-(8-Aza-spiro[4.5]dec-8-ylcarbamoyl)-4-(3,5-dichl...)
Show SMILES OC(=O)CCC(NC(=O)c1cc(Cl)cc(Cl)c1)C(=O)NN1CCC2(CCCC2)CC1
Show InChI InChI=1S/C21H27Cl2N3O4/c22-15-11-14(12-16(23)13-15)19(29)24-17(3-4-18(27)28)20(30)25-26-9-7-21(8-10-26)5-1-2-6-21/h11-13,17H,1-10H2,(H,24,29)(H,25,30)(H,27,28)
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Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008220
PNG
(4-(2-Aza-spiro[4.5]dec-2-ylcarbamoyl)-4-(3,5-dichl...)
Show SMILES OC(=O)CCC(NC(=O)c1cc(Cl)cc(Cl)c1)C(=O)NN1CCC2(C1)CCCCC2
Show InChI InChI=1S/C21H27Cl2N3O4/c22-15-10-14(11-16(23)12-15)19(29)24-17(4-5-18(27)28)20(30)25-26-9-8-21(13-26)6-2-1-3-7-21/h10-12,17H,1-9,13H2,(H,24,29)(H,25,30)(H,27,28)
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Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008219
PNG
(4-(3-Aza-spiro[5.5]undec-3-ylcarbamoyl)-4-(3-chlor...)
Show SMILES OC(=O)CCC(NC(=O)c1cccc(Cl)c1)C(=O)NN1CCC2(CCCCC2)CC1
Show InChI InChI=1S/C22H30ClN3O4/c23-17-6-4-5-16(15-17)20(29)24-18(7-8-19(27)28)21(30)25-26-13-11-22(12-14-26)9-2-1-3-10-22/h4-6,15,18H,1-3,7-14H2,(H,24,29)(H,25,30)(H,27,28)
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Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(Homo sapiens (Human))		BDBM50008175
PNG
(4-(8-Aza-spiro[4.5]dec-8-ylcarbamoyl)-4-(3-chloro-...)
Show SMILES OC(=O)CCC(NC(=O)c1cccc(Cl)c1)C(=O)NN1CCC2(CCCC2)CC1
Show InChI InChI=1S/C21H28ClN3O4/c22-16-5-3-4-15(14-16)19(28)23-17(6-7-18(26)27)20(29)24-25-12-10-21(11-13-25)8-1-2-9-21/h3-5,14,17H,1-2,6-13H2,(H,23,28)(H,24,29)(H,26,27)
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Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Concentration required to inhibit by 50% the specific binding of [3H]pentagastrin to Cholecystokinin type B receptor in rabbit gastric gland

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008207
PNG
(4-(3-Aza-spiro[5.5]undec-3-ylcarbamoyl)-4-[(quinol...)
Show SMILES OC(=O)CCC(NC(=O)c1cnc2ccccc2c1)C(=O)NN1CCC2(CCCCC2)CC1
Show InChI InChI=1S/C25H32N4O4/c30-22(31)9-8-21(27-23(32)19-16-18-6-2-3-7-20(18)26-17-19)24(33)28-29-14-12-25(13-15-29)10-4-1-5-11-25/h2-3,6-7,16-17,21H,1,4-5,8-15H2,(H,27,32)(H,28,33)(H,30,31)
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Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008192
PNG
(4-(8-Aza-spiro[4.5]dec-8-ylcarbamoyl)-4-(2,3-dichl...)
Show SMILES OC(=O)CCC(NC(=O)c1cccc(Cl)c1Cl)C(=O)NN1CCC2(CCCC2)CC1
Show InChI InChI=1S/C21H27Cl2N3O4/c22-15-5-3-4-14(18(15)23)19(29)24-16(6-7-17(27)28)20(30)25-26-12-10-21(11-13-26)8-1-2-9-21/h3-5,16H,1-2,6-13H2,(H,24,29)(H,25,30)(H,27,28)
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Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008166
PNG
(4-(3-Chloro-benzoylamino)-4-(3,3-diethyl-pentylcar...)
Show SMILES CCC(CC)(CC)CCNC(=O)C(CCC(O)=O)NC(=O)c1cccc(Cl)c1
Show InChI InChI=1S/C21H31ClN2O4/c1-4-21(5-2,6-3)12-13-23-20(28)17(10-11-18(25)26)24-19(27)15-8-7-9-16(22)14-15/h7-9,14,17H,4-6,10-13H2,1-3H3,(H,23,28)(H,24,27)(H,25,26)
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Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008201
PNG
(4-(3-Chloro-benzoylamino)-4-cyclodecylcarbamoyl-bu...)
Show SMILES OC(=O)CCC(NC(=O)c1cccc(Cl)c1)C(=O)NC1CCCCCCCCC1
Show InChI InChI=1S/C22H31ClN2O4/c23-17-10-8-9-16(15-17)21(28)25-19(13-14-20(26)27)22(29)24-18-11-6-4-2-1-3-5-7-12-18/h8-10,15,18-19H,1-7,11-14H2,(H,24,29)(H,25,28)(H,26,27)
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Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008175
PNG
(4-(8-Aza-spiro[4.5]dec-8-ylcarbamoyl)-4-(3-chloro-...)
Show SMILES OC(=O)CCC(NC(=O)c1cccc(Cl)c1)C(=O)NN1CCC2(CCCC2)CC1
Show InChI InChI=1S/C21H28ClN3O4/c22-16-5-3-4-15(14-16)19(28)23-17(6-7-18(26)27)20(29)24-25-12-10-21(11-13-25)8-1-2-9-21/h3-5,14,17H,1-2,6-13H2,(H,23,28)(H,24,29)(H,26,27)
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Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008205
PNG
(4-(3,3-Dimethyl-butylcarbamoyl)-4-[(1H-indole-2-ca...)
Show SMILES CC(C)(C)CCNC(=O)C(CCC(O)=O)NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C20H27N3O4/c1-20(2,3)10-11-21-18(26)15(8-9-17(24)25)23-19(27)16-12-13-6-4-5-7-14(13)22-16/h4-7,12,15,22H,8-11H2,1-3H3,(H,21,26)(H,23,27)(H,24,25)
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Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Cholecystokinin receptor type A


(RAT)		BDBM50008173
PNG
(4-(8-Aza-spiro[4.5]dec-8-ylcarbamoyl)-4-[(quinolin...)
Show SMILES OC(=O)CCC(NC(=O)c1cnc2ccccc2c1)C(=O)NN1CCC2(CCCC2)CC1
Show InChI InChI=1S/C24H30N4O4/c29-21(30)8-7-20(23(32)27-28-13-11-24(12-14-28)9-3-4-10-24)26-22(31)18-15-17-5-1-2-6-19(17)25-16-18/h1-2,5-6,15-16,20H,3-4,7-14H2,(H,26,31)(H,27,32)(H,29,30)
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Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Concentration required to inhibit by 50% specific binding of [125I](BH)-CCK-8 to cholecystokinin type A receptor in rat pancreatic acini

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Cholecystokinin receptor type A


(RAT)		BDBM50008198
PNG
(4-(8-Aza-spiro[4.5]dec-8-ylcarbamoyl)-4-(3,4-dichl...)
Show SMILES OC(=O)CCC(NC(=O)c1ccc(Cl)c(Cl)c1)C(=O)NN1CCC2(CCCC2)CC1
Show InChI InChI=1S/C21H27Cl2N3O4/c22-15-4-3-14(13-16(15)23)19(29)24-17(5-6-18(27)28)20(30)25-26-11-9-21(10-12-26)7-1-2-8-21/h3-4,13,17H,1-2,5-12H2,(H,24,29)(H,25,30)(H,27,28)
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Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Concentration required to inhibit by 50% specific binding of [125I](BH)-CCK-8 to cholecystokinin type A receptor in rat pancreatic acini

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008178
PNG
(4-(4,4-Dimethyl-pentylcarbamoyl)-4-[(quinoline-3-c...)
Show SMILES CC(C)(C)CCCNC(=O)C(CCC(O)=O)NC(=O)c1cnc2ccccc2c1
Show InChI InChI=1S/C22H29N3O4/c1-22(2,3)11-6-12-23-21(29)18(9-10-19(26)27)25-20(28)16-13-15-7-4-5-8-17(15)24-14-16/h4-5,7-8,13-14,18H,6,9-12H2,1-3H3,(H,23,29)(H,25,28)(H,26,27)
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Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Cholecystokinin receptor type A


(RAT)		BDBM50024321
PNG
(3-{2-[2-(3-tert-Butoxycarbonylamino-propionylamino...)
Show SMILES CSCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CCNC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C37H49N7O9S/c1-37(2,3)53-36(52)39-16-14-30(45)41-28(19-23-21-40-25-13-9-8-12-24(23)25)34(50)42-26(15-17-54-4)33(49)44-29(20-31(46)47)35(51)43-27(32(38)48)18-22-10-6-5-7-11-22/h5-13,21,26-29,40H,14-20H2,1-4H3,(H2,38,48)(H,39,52)(H,41,45)(H,42,50)(H,43,51)(H,44,49)(H,46,47)/t26-,27-,28-,29-/m0/s1
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Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Concentration required to inhibit by 50% specific binding of [125I](BH)-CCK-8 to cholecystokinin type A receptor in rat pancreatic acini

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008165
PNG
(4-(3-Chloro-benzoylamino)-4-(decahydro-naphthalen-...)
Show SMILES OC(=O)CCC(NC(=O)c1cccc(Cl)c1)C(=O)NC1CCC2CCCCC2C1
Show InChI InChI=1S/C22H29ClN2O4/c23-17-7-3-6-16(12-17)21(28)25-19(10-11-20(26)27)22(29)24-18-9-8-14-4-1-2-5-15(14)13-18/h3,6-7,12,14-15,18-19H,1-2,4-5,8-11,13H2,(H,24,29)(H,25,28)(H,26,27)
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Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008212
PNG
(4-(3-Chloro-benzoylamino)-4-(3-ethyl-3-methyl-pent...)
Show SMILES CCC(C)(CC)CCNC(=O)C(CCC(O)=O)NC(=O)c1cccc(Cl)c1
Show InChI InChI=1S/C20H29ClN2O4/c1-4-20(3,5-2)11-12-22-19(27)16(9-10-17(24)25)23-18(26)14-7-6-8-15(21)13-14/h6-8,13,16H,4-5,9-12H2,1-3H3,(H,22,27)(H,23,26)(H,24,25)
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Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(Homo sapiens (Human))		BDBM50008202
PNG
(4-(3,5-Dichloro-benzoylamino)-4-(3,3-dimethyl-buty...)
Show SMILES CC(C)(C)CCNC(=O)C(CCC(O)=O)NC(=O)c1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C18H24Cl2N2O4/c1-18(2,3)6-7-21-17(26)14(4-5-15(23)24)22-16(25)11-8-12(19)10-13(20)9-11/h8-10,14H,4-7H2,1-3H3,(H,21,26)(H,22,25)(H,23,24)
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n/an/a 2.00E+3n/an/an/an/an/an/a



Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Concentration required to inhibit by 50% the specific binding of [3H]pentagastrin to Cholecystokinin type B receptor in rabbit gastric gland

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Cholecystokinin receptor type A


(RAT)		BDBM50008211
PNG
(4-(8-Aza-spiro[4.5]dec-8-ylcarbamoyl)-4-[(naphthal...)
Show SMILES OC(=O)CCC(NC(=O)c1ccc2ccccc2c1)C(=O)NN1CCC2(CCCC2)CC1
Show InChI InChI=1S/C25H31N3O4/c29-22(30)10-9-21(24(32)27-28-15-13-25(14-16-28)11-3-4-12-25)26-23(31)20-8-7-18-5-1-2-6-19(18)17-20/h1-2,5-8,17,21H,3-4,9-16H2,(H,26,31)(H,27,32)(H,29,30)
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Curated by ChEMBL


Assay Description
Concentration required to inhibit by 50% specific binding of [125I](BH)-CCK-8 to cholecystokinin type A receptor in rat pancreatic acini

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(Homo sapiens (Human))		BDBM50008184
PNG
(4-(3-Chloro-benzoylamino)-4-(3,3-dimethyl-butylcar...)
Show SMILES CC(C)(C)CCNC(=O)C(CCC(O)=O)NC(=O)c1cccc(Cl)c1
Show InChI InChI=1S/C18H25ClN2O4/c1-18(2,3)9-10-20-17(25)14(7-8-15(22)23)21-16(24)12-5-4-6-13(19)11-12/h4-6,11,14H,7-10H2,1-3H3,(H,20,25)(H,21,24)(H,22,23)
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n/an/a 2.20E+3n/an/an/an/an/an/a



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Curated by ChEMBL


Assay Description
Concentration required to inhibit by 50% the specific binding of [3H]pentagastrin to Cholecystokinin type B receptor in rabbit gastric gland

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008197
PNG
(4-(3-Chloro-benzoylamino)-5-(decahydro-isoquinolin...)
Show SMILES OC(=O)CCC(NC(=O)c1cccc(Cl)c1)C(=O)C1CC2CCCCC2CN1
Show InChI InChI=1S/C21H27ClN2O4/c22-16-7-3-6-14(10-16)21(28)24-17(8-9-19(25)26)20(27)18-11-13-4-1-2-5-15(13)12-23-18/h3,6-7,10,13,15,17-18,23H,1-2,4-5,8-9,11-12H2,(H,24,28)(H,25,26)
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n/an/a 2.30E+3n/an/an/an/an/an/a



Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50453155
PNG
(CHEMBL2111826)
Show SMILES OC(=O)CC[C@H](NC(=O)c1ccc(Cl)c(Cl)c1)C(=O)NN1CCC2(CCCC2)CC1 |r|
Show InChI InChI=1S/C21H27Cl2N3O4/c22-15-4-3-14(13-16(15)23)19(29)24-17(5-6-18(27)28)20(30)25-26-11-9-21(10-12-26)7-1-2-8-21/h3-4,13,17H,1-2,5-12H2,(H,24,29)(H,25,30)(H,27,28)/t17-/m0/s1
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n/an/a 2.30E+3n/an/an/an/an/an/a



Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008206
PNG
(4-(3,3-Dimethyl-butylcarbamoyl)-4-[(naphthalene-2-...)
Show SMILES CC(C)(C)CCNC(=O)C(CCC(O)=O)NC(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C22H28N2O4/c1-22(2,3)12-13-23-21(28)18(10-11-19(25)26)24-20(27)17-9-8-15-6-4-5-7-16(15)14-17/h4-9,14,18H,10-13H2,1-3H3,(H,23,28)(H,24,27)(H,25,26)
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n/an/a 2.30E+3n/an/an/an/an/an/a



Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008173
PNG
(4-(8-Aza-spiro[4.5]dec-8-ylcarbamoyl)-4-[(quinolin...)
Show SMILES OC(=O)CCC(NC(=O)c1cnc2ccccc2c1)C(=O)NN1CCC2(CCCC2)CC1
Show InChI InChI=1S/C24H30N4O4/c29-21(30)8-7-20(23(32)27-28-13-11-24(12-14-28)9-3-4-10-24)26-22(31)18-15-17-5-1-2-6-19(17)25-16-18/h1-2,5-6,15-16,20H,3-4,7-14H2,(H,26,31)(H,27,32)(H,29,30)
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Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008179
PNG
(4-(8-Aza-spiro[4.5]dec-8-ylcarbamoyl)-4-(4-isoprop...)
Show SMILES CC(C)c1ccc(cc1)C(=O)NC(CCC(O)=O)C(=O)NN1CCC2(CCCC2)CC1
Show InChI InChI=1S/C24H35N3O4/c1-17(2)18-5-7-19(8-6-18)22(30)25-20(9-10-21(28)29)23(31)26-27-15-13-24(14-16-27)11-3-4-12-24/h5-8,17,20H,3-4,9-16H2,1-2H3,(H,25,30)(H,26,31)(H,28,29)
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n/an/a 2.70E+3n/an/an/an/an/an/a



Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50453156
PNG
(CHEMBL2111825)
Show SMILES OC(=O)CC[C@H](NC(=O)c1cccc(Cl)c1)C(=O)NCCC12CC3CC(CC(C3)C1)C2 |r,TLB:28:27:30:23.22.24,28:23:30:27.29.26,24:25:29:23.22.28,THB:24:23:29:25.30.26|
Show InChI InChI=1S/C24H31ClN2O4/c25-19-3-1-2-18(11-19)22(30)27-20(4-5-21(28)29)23(31)26-7-6-24-12-15-8-16(13-24)10-17(9-15)14-24/h1-3,11,15-17,20H,4-10,12-14H2,(H,26,31)(H,27,30)(H,28,29)/t15?,16?,17?,20-,24?/m0/s1
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n/an/a 2.80E+3n/an/an/an/an/an/a



Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008182
PNG
(4-(2,3-Dichloro-benzoylamino)-4-(3,3-dimethyl-buty...)
Show SMILES CC(C)(C)CCNC(=O)C(CCC(O)=O)NC(=O)c1cccc(Cl)c1Cl
Show InChI InChI=1S/C18H24Cl2N2O4/c1-18(2,3)9-10-21-17(26)13(7-8-14(23)24)22-16(25)11-5-4-6-12(19)15(11)20/h4-6,13H,7-10H2,1-3H3,(H,21,26)(H,22,25)(H,23,24)
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n/an/a 2.90E+3n/an/an/an/an/an/a



Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008203
PNG
(4-(3,5-Dichloro-benzoylamino)-4-dipentylcarbamoyl-...)
Show SMILES CCCCCN(CCCCC)C(=O)C(CCC(O)=O)NC(=O)c1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C22H32Cl2N2O4/c1-3-5-7-11-26(12-8-6-4-2)22(30)19(9-10-20(27)28)25-21(29)16-13-17(23)15-18(24)14-16/h13-15,19H,3-12H2,1-2H3,(H,25,29)(H,27,28)
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n/an/a 3.00E+3n/an/an/an/an/an/a



Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008170
PNG
(4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-...)
Show SMILES CCCCCN(CCCCC)C(=O)C(CCC(O)=O)NC(=O)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C22H32Cl2N2O4/c1-3-5-7-13-26(14-8-6-4-2)22(30)19(11-12-20(27)28)25-21(29)16-9-10-17(23)18(24)15-16/h9-10,15,19H,3-8,11-14H2,1-2H3,(H,25,29)(H,27,28)
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n/an/a 3.00E+3n/an/an/an/an/an/a



Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50453154
PNG
(CHEMBL2111827)
Show SMILES OC(=O)CC[C@H](NC(=O)c1cc(Cl)cc(Cl)c1)C(=O)NN1CCC2(CCCC2)CC1 |r|
Show InChI InChI=1S/C21H27Cl2N3O4/c22-15-11-14(12-16(23)13-15)19(29)24-17(3-4-18(27)28)20(30)25-26-9-7-21(8-10-26)5-1-2-6-21/h11-13,17H,1-10H2,(H,24,29)(H,25,30)(H,27,28)/t17-/m0/s1
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n/an/a 3.00E+3n/an/an/an/an/an/a



Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008191
PNG
(4-(3,4-Dichloro-benzoylamino)-4-(3,3-dimethyl-buty...)
Show SMILES CC(C)(C)CCNC(=O)C(CCC(O)=O)NC(=O)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C18H24Cl2N2O4/c1-18(2,3)8-9-21-17(26)14(6-7-15(23)24)22-16(25)11-4-5-12(19)13(20)10-11/h4-5,10,14H,6-9H2,1-3H3,(H,21,26)(H,22,25)(H,23,24)
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n/an/a 3.10E+3n/an/an/an/an/an/a



Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
Gastrin/cholecystokinin type B receptor


(RAT)		BDBM50008181
PNG
(4-(3-Chloro-benzoylamino)-4-(4,4-dimethyl-pentylca...)
Show SMILES CC(C)(C)CCCNC(=O)C(CCC(O)=O)NC(=O)c1cccc(Cl)c1
Show InChI InChI=1S/C19H27ClN2O4/c1-19(2,3)10-5-11-21-18(26)15(8-9-16(23)24)22-17(25)13-6-4-7-14(20)12-13/h4,6-7,12,15H,5,8-11H2,1-3H3,(H,21,26)(H,22,25)(H,23,24)
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n/an/a 3.20E+3n/an/an/an/an/an/a



Rotta Research Laboratorium

Curated by ChEMBL


Assay Description
Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex

J Med Chem 35: 28-38 (1992)


BindingDB Entry DOI: 10.7270/Q2XS5W11
More data for this
Ligand-Target Pair
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