Compile Data Set for Download or QSAR

Found 61 hits Enz. Inhib. hit(s) with all data for entry = 50037727   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189733 (CHEMBL379629 | ethyl 3-(N-benzyl-N-methylaminometh...) Show SMILES CCOC(=O)c1cn(Cc2c(F)cccc2F)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(NC(=O)NC)cc1 Show InChI InChI=1S/C34H32F2N4O4S/c1-4-44-33(42)26-20-40(19-24-27(35)11-8-12-28(24)36)32-29(30(26)41)25(18-39(3)17-21-9-6-5-7-10-21)31(45-32)22-13-15-23(16-14-22)38-34(43)37-2/h5-16,20H,4,17-19H2,1-3H3,(H2,37,38,43)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0600	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189704 (3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobe...) Show SMILES CNC(=O)Nc1ccc(cc1)-c1sc2n(Cc3c(F)cccc3F)cc(C(=O)C(C)C)c(=O)c2c1CN(C)Cc1ccccc1 Show InChI InChI=1S/C35H34F2N4O3S/c1-21(2)31(42)27-20-41(19-25-28(36)11-8-12-29(25)37)34-30(32(27)43)26(18-40(4)17-22-9-6-5-7-10-22)33(45-34)23-13-15-24(16-14-23)39-35(44)38-3/h5-16,20-21H,17-19H2,1-4H3,(H2,38,39,44)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0700	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of LHRH-stimulated arachidonic acid release in CHO cells expressing human LHRH receptor				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189716 (CHEMBL210294 | ethyl 3-(N-benzyl-N-methylaminometh...) Show SMILES CCOC(=O)c1cn(Cc2ccccc2F)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(NC(=O)NC)cc1 Show InChI InChI=1S/C34H33FN4O4S/c1-4-43-33(41)27-21-39(19-24-12-8-9-13-28(24)35)32-29(30(27)40)26(20-38(3)18-22-10-6-5-7-11-22)31(44-32)23-14-16-25(17-15-23)37-34(42)36-2/h5-17,21H,4,18-20H2,1-3H3,(H2,36,37,42)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0700	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189701 (3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobe...) Show SMILES CCC(O)C(=O)Nc1ccc(cc1)-c1sc2n(Cc3c(F)cccc3F)cc(C(=O)C(C)C)c(=O)c2c1CN(C)Cc1ccccc1 Show InChI InChI=1S/C37H37F2N3O4S/c1-5-31(43)36(46)40-25-16-14-24(15-17-25)35-27(19-41(4)18-23-10-7-6-8-11-23)32-34(45)28(33(44)22(2)3)21-42(37(32)47-35)20-26-29(38)12-9-13-30(26)39/h6-17,21-22,31,43H,5,18-20H2,1-4H3,(H,40,46)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of LHRH-stimulated arachidonic acid release in CHO cells expressing human LHRH receptor				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189703 (CHEMBL208812 | N-(4-(7-(2,6-difluorobenzyl)-5-benz...) Show SMILES CC(C)C(=O)Nc1ccc(cc1)-c1sc2n(Cc3c(F)cccc3F)cc(C(=O)c3ccccc3)c(=O)c2c1CN(C)Cc1ccccc1 Show InChI InChI=1S/C40H35F2N3O3S/c1-25(2)39(48)43-29-19-17-28(18-20-29)38-31(22-44(3)21-26-11-6-4-7-12-26)35-37(47)32(36(46)27-13-8-5-9-14-27)24-45(40(35)49-38)23-30-33(41)15-10-16-34(30)42/h4-20,24-25H,21-23H2,1-3H3,(H,43,48)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189701 (3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobe...) Show SMILES CCC(O)C(=O)Nc1ccc(cc1)-c1sc2n(Cc3c(F)cccc3F)cc(C(=O)C(C)C)c(=O)c2c1CN(C)Cc1ccccc1 Show InChI InChI=1S/C37H37F2N3O4S/c1-5-31(43)36(46)40-25-16-14-24(15-17-25)35-27(19-41(4)18-23-10-7-6-8-11-23)32-34(45)28(33(44)22(2)3)21-42(37(32)47-35)20-26-29(38)12-9-13-30(26)39/h6-17,21-22,31,43H,5,18-20H2,1-4H3,(H,40,46)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189730 (CHEMBL210709 | ethyl 3-(N-benzyl-N-methylaminometh...) Show SMILES CCOC(=O)c1cn(Cc2c(F)cccc2F)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(NC(=O)CC)cc1 Show InChI InChI=1S/C35H33F2N3O4S/c1-4-30(41)38-24-16-14-23(15-17-24)33-26(19-39(3)18-22-10-7-6-8-11-22)31-32(42)27(35(43)44-5-2)21-40(34(31)45-33)20-25-28(36)12-9-13-29(25)37/h6-17,21H,4-5,18-20H2,1-3H3,(H,38,41)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189704 (3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobe...) Show SMILES CNC(=O)Nc1ccc(cc1)-c1sc2n(Cc3c(F)cccc3F)cc(C(=O)C(C)C)c(=O)c2c1CN(C)Cc1ccccc1 Show InChI InChI=1S/C35H34F2N4O3S/c1-21(2)31(42)27-20-41(19-25-28(36)11-8-12-29(25)37)34-30(32(27)43)26(18-40(4)17-22-9-6-5-7-10-22)33(45-34)23-13-15-24(16-14-23)39-35(44)38-3/h5-16,20-21H,17-19H2,1-4H3,(H2,38,39,44)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189704 (3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobe...) Show SMILES CNC(=O)Nc1ccc(cc1)-c1sc2n(Cc3c(F)cccc3F)cc(C(=O)C(C)C)c(=O)c2c1CN(C)Cc1ccccc1 Show InChI InChI=1S/C35H34F2N4O3S/c1-21(2)31(42)27-20-41(19-25-28(36)11-8-12-29(25)37)34-30(32(27)43)26(18-40(4)17-22-9-6-5-7-10-22)33(45-34)23-13-15-24(16-14-23)39-35(44)38-3/h5-16,20-21H,17-19H2,1-4H3,(H2,38,39,44)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to monkey recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189727 (CHEMBL211503 | N-(4-(7-(2,6-difluorobenzyl)-3-((be...) Show SMILES CC(C)C(=O)Nc1ccc(cc1)-c1sc2n(Cc3c(F)cccc3F)cc(C(=O)C(C)C)c(=O)c2c1CN(C)Cc1ccccc1 Show InChI InChI=1S/C37H37F2N3O3S/c1-22(2)33(43)29-21-42(20-27-30(38)12-9-13-31(27)39)37-32(34(29)44)28(19-41(5)18-24-10-7-6-8-11-24)35(46-37)25-14-16-26(17-15-25)40-36(45)23(3)4/h6-17,21-23H,18-20H2,1-5H3,(H,40,45)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189720 (3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobe...) Show SMILES CC(C)C(=O)c1cn(Cc2c(F)cccc2F)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(NC(=O)C(C)(C)O)cc1 Show InChI InChI=1S/C37H37F2N3O4S/c1-22(2)32(43)28-21-42(20-26-29(38)12-9-13-30(26)39)35-31(33(28)44)27(19-41(5)18-23-10-7-6-8-11-23)34(47-35)24-14-16-25(17-15-24)40-36(45)37(3,4)46/h6-17,21-22,46H,18-20H2,1-5H3,(H,40,45)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189707 (3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobe...) Show SMILES CC(C)C(=O)c1cn(Cc2c(F)cccc2F)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(NC(=O)CO)cc1 Show InChI InChI=1S/C35H33F2N3O4S/c1-21(2)32(43)27-19-40(18-25-28(36)10-7-11-29(25)37)35-31(33(27)44)26(17-39(3)16-22-8-5-4-6-9-22)34(45-35)23-12-14-24(15-13-23)38-30(42)20-41/h4-15,19,21,41H,16-18,20H2,1-3H3,(H,38,42)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50067485 (3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...) Show SMILES CC(C)OC(=O)c1cn(Cc2c(F)cccc2F)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(NC(=O)C(C)C)cc1 Show InChI InChI=1S/C37H37F2N3O4S/c1-22(2)35(44)40-26-16-14-25(15-17-26)34-28(19-41(5)18-24-10-7-6-8-11-24)32-33(43)29(37(45)46-23(3)4)21-42(36(32)47-34)20-27-30(38)12-9-13-31(27)39/h6-17,21-23H,18-20H2,1-5H3,(H,40,44)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189723 (CHEMBL540109 | ethyl 3-(N-benzyl-N-methylaminometh...) Show SMILES CCOC(=O)c1cn(Cc2c(F)cccc2F)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(NC(=O)C(C)C)cc1 Show InChI InChI=1S/C36H35F2N3O4S/c1-5-45-36(44)28-21-41(20-26-29(37)12-9-13-30(26)38)35-31(32(28)42)27(19-40(4)18-23-10-7-6-8-11-23)33(46-35)24-14-16-25(17-15-24)39-34(43)22(2)3/h6-17,21-22H,5,18-20H2,1-4H3,(H,39,43)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50369395 (ELIGARD | LEUPROLIDE) Show SMILES CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCC(=O)N1 |r| Show InChI InChI=1S/C59H84N16O12/c1-6-63-57(86)48-14-10-22-75(48)58(87)41(13-9-21-64-59(60)61)68-51(80)42(23-32(2)3)69-52(81)43(24-33(4)5)70-53(82)44(25-34-15-17-37(77)18-16-34)71-56(85)47(30-76)74-54(83)45(26-35-28-65-39-12-8-7-11-38(35)39)72-55(84)46(27-36-29-62-31-66-36)73-50(79)40-19-20-49(78)67-40/h7-8,11-12,15-18,28-29,31-33,40-48,65,76-77H,6,9-10,13-14,19-27,30H2,1-5H3,(H,62,66)(H,63,86)(H,67,78)(H,68,80)(H,69,81)(H,70,82)(H,71,85)(H,72,84)(H,73,79)(H,74,83)(H4,60,61,64)/t40-,41-,42-,43+,44-,45-,46-,47-,48-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189713 (3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobe...) Show SMILES CCC(=O)c1cn(Cc2c(F)cccc2F)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(NC(=O)C(C)C)cc1 Show InChI InChI=1S/C36H35F2N3O3S/c1-5-31(42)27-21-41(20-26-29(37)12-9-13-30(26)38)36-32(33(27)43)28(19-40(4)18-23-10-7-6-8-11-23)34(45-36)24-14-16-25(17-15-24)39-35(44)22(2)3/h6-17,21-22H,5,18-20H2,1-4H3,(H,39,44)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189712 (CHEMBL379198 | ethyl 3-(N-benzyl-N-methylaminometh...) Show SMILES CCOC(=O)c1cn(Cc2ccccc2)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(NC(=O)CC)cc1 Show InChI InChI=1S/C35H35N3O4S/c1-4-30(39)36-27-18-16-26(17-19-27)33-28(22-37(3)20-24-12-8-6-9-13-24)31-32(40)29(35(41)42-5-2)23-38(34(31)43-33)21-25-14-10-7-11-15-25/h6-19,23H,4-5,20-22H2,1-3H3,(H,36,39)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189736 (3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobe...) Show SMILES CC(C)C(O)c1cn(Cc2c(F)cccc2F)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(NC(=O)C(C)C)cc1 Show InChI InChI=1S/C37H39F2N3O3S/c1-22(2)33(43)29-21-42(20-27-30(38)12-9-13-31(27)39)37-32(34(29)44)28(19-41(5)18-24-10-7-6-8-11-24)35(46-37)25-14-16-26(17-15-25)40-36(45)23(3)4/h6-17,21-23,33,43H,18-20H2,1-5H3,(H,40,45)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50369395 (ELIGARD | LEUPROLIDE) Show SMILES CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCC(=O)N1 |r| Show InChI InChI=1S/C59H84N16O12/c1-6-63-57(86)48-14-10-22-75(48)58(87)41(13-9-21-64-59(60)61)68-51(80)42(23-32(2)3)69-52(81)43(24-33(4)5)70-53(82)44(25-34-15-17-37(77)18-16-34)71-56(85)47(30-76)74-54(83)45(26-35-28-65-39-12-8-7-11-38(35)39)72-55(84)46(27-36-29-62-31-66-36)73-50(79)40-19-20-49(78)67-40/h7-8,11-12,15-18,28-29,31-33,40-48,65,76-77H,6,9-10,13-14,19-27,30H2,1-5H3,(H,62,66)(H,63,86)(H,67,78)(H,68,80)(H,69,81)(H,70,82)(H,71,85)(H,72,84)(H,73,79)(H,74,83)(H4,60,61,64)/t40-,41-,42-,43+,44-,45-,46-,47-,48-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to rat anterior pituitary LHRH receptor				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50067485 (3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...) Show SMILES CC(C)OC(=O)c1cn(Cc2c(F)cccc2F)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(NC(=O)C(C)C)cc1 Show InChI InChI=1S/C37H37F2N3O4S/c1-22(2)35(44)40-26-16-14-25(15-17-26)34-28(19-41(5)18-24-10-7-6-8-11-24)32-33(43)29(37(45)46-23(3)4)21-42(36(32)47-34)20-27-30(38)12-9-13-31(27)39/h6-17,21-23H,18-20H2,1-5H3,(H,40,44)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of LHRH-stimulated arachidonic acid release in CHO cells expressing human LHRH receptor				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189740 (CHEMBL210888 | ethyl 7-benzyl-3-((benzyl(methyl)am...) Show SMILES CCOC(=O)c1cn(Cc2ccccc2)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(NC(=O)C(C)C)cc1 Show InChI InChI=1S/C36H37N3O4S/c1-5-43-36(42)30-23-39(21-26-14-10-7-11-15-26)35-31(32(30)40)29(22-38(4)20-25-12-8-6-9-13-25)33(44-35)27-16-18-28(19-17-27)37-34(41)24(2)3/h6-19,23-24H,5,20-22H2,1-4H3,(H,37,41)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50369395 (ELIGARD | LEUPROLIDE) Show SMILES CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCC(=O)N1 |r| Show InChI InChI=1S/C59H84N16O12/c1-6-63-57(86)48-14-10-22-75(48)58(87)41(13-9-21-64-59(60)61)68-51(80)42(23-32(2)3)69-52(81)43(24-33(4)5)70-53(82)44(25-34-15-17-37(77)18-16-34)71-56(85)47(30-76)74-54(83)45(26-35-28-65-39-12-8-7-11-38(35)39)72-55(84)46(27-36-29-62-31-66-36)73-50(79)40-19-20-49(78)67-40/h7-8,11-12,15-18,28-29,31-33,40-48,65,76-77H,6,9-10,13-14,19-27,30H2,1-5H3,(H,62,66)(H,63,86)(H,67,78)(H,68,80)(H,69,81)(H,70,82)(H,71,85)(H,72,84)(H,73,79)(H,74,83)(H4,60,61,64)/t40-,41-,42-,43+,44-,45-,46-,47-,48-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to monkey anterior pituitary LHRH receptor				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189701 (3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobe...) Show SMILES CCC(O)C(=O)Nc1ccc(cc1)-c1sc2n(Cc3c(F)cccc3F)cc(C(=O)C(C)C)c(=O)c2c1CN(C)Cc1ccccc1 Show InChI InChI=1S/C37H37F2N3O4S/c1-5-31(43)36(46)40-25-16-14-24(15-17-25)35-27(19-41(4)18-23-10-7-6-8-11-23)32-34(45)28(33(44)22(2)3)21-42(37(32)47-35)20-26-29(38)12-9-13-30(26)39/h6-17,21-22,31,43H,5,18-20H2,1-4H3,(H,40,46)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to monkey recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189734 (CHEMBL264121 | ethyl 2-(4-benzamidophenyl)-7-benzy...) Show SMILES CCOC(=O)c1cn(Cc2ccccc2)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(NC(=O)c2ccccc2)cc1 Show InChI InChI=1S/C39H35N3O4S/c1-3-46-39(45)33-26-42(24-28-15-9-5-10-16-28)38-34(35(33)43)32(25-41(2)23-27-13-7-4-8-14-27)36(47-38)29-19-21-31(22-20-29)40-37(44)30-17-11-6-12-18-30/h4-22,26H,3,23-25H2,1-2H3,(H,40,44)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50067485 (3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...) Show SMILES CC(C)OC(=O)c1cn(Cc2c(F)cccc2F)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(NC(=O)C(C)C)cc1 Show InChI InChI=1S/C37H37F2N3O4S/c1-22(2)35(44)40-26-16-14-25(15-17-26)34-28(19-41(5)18-24-10-7-6-8-11-24)32-33(43)29(37(45)46-23(3)4)21-42(36(32)47-34)20-27-30(38)12-9-13-31(27)39/h6-17,21-23H,18-20H2,1-5H3,(H,40,44)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to monkey recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189726 (CHEMBL264574 | ethyl 3-(N-benzyl-N-methylaminometh...) Show SMILES CCOC(=O)c1cn(Cc2ccccc2)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(cc1)N(C)C(=O)NC Show InChI InChI=1S/C35H36N4O4S/c1-5-43-34(41)29-23-39(21-25-14-10-7-11-15-25)33-30(31(29)40)28(22-37(3)20-24-12-8-6-9-13-24)32(44-33)26-16-18-27(19-17-26)38(4)35(42)36-2/h6-19,23H,5,20-22H2,1-4H3,(H,36,42)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189728 (CHEMBL211098 | ethyl 2-(4-acetamidophenyl)-7-benzy...) Show SMILES CCOC(=O)c1cn(Cc2ccccc2)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(NC(C)=O)cc1 Show InChI InChI=1S/C34H33N3O4S/c1-4-41-34(40)29-22-37(20-25-13-9-6-10-14-25)33-30(31(29)39)28(21-36(3)19-24-11-7-5-8-12-24)32(42-33)26-15-17-27(18-16-26)35-23(2)38/h5-18,22H,4,19-21H2,1-3H3,(H,35,38)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50067485 (3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...) Show SMILES CC(C)OC(=O)c1cn(Cc2c(F)cccc2F)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(NC(=O)C(C)C)cc1 Show InChI InChI=1S/C37H37F2N3O4S/c1-22(2)35(44)40-26-16-14-25(15-17-26)34-28(19-41(5)18-24-10-7-6-8-11-24)32-33(43)29(37(45)46-23(3)4)21-42(36(32)47-34)20-27-30(38)12-9-13-31(27)39/h6-17,21-23H,18-20H2,1-5H3,(H,40,44)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to monkey anterior pituitary LHRH receptor				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189708 ((S)-1-((S)-2-((S)-2-(2-((S)-2-((S)-2-((S)-2-((S)-3...) Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1cc2ccccc2[nH]1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(N)=O |wU:12.21,44.54,wD:30.43,4.4,54.57,63.67,24.27,77.83,(.86,.61,;2.37,.33,;2.89,-1.12,;3.37,1.5,;4.88,1.23,;5.88,2.4,;5.36,3.85,;3.85,4.13,;6.36,5.02,;5.85,6.47,;6.84,7.66,;8.36,7.37,;6.33,9.1,;7.32,10.28,;8.84,10,;9.35,8.55,;10.86,8.27,;11.86,9.45,;13.38,9.16,;11.34,10.9,;9.83,11.17,;4.81,9.39,;4.3,10.83,;5.29,12,;2.78,11.11,;1.78,9.93,;.27,10.22,;2.26,12.57,;.75,12.83,;-.25,11.67,;.23,14.29,;-1.28,14.58,;-2.28,13.4,;-3.82,13.5,;-4.4,12.09,;-5.85,11.56,;-6.12,10.06,;-4.94,9.06,;-3.5,9.58,;-3.23,11.09,;-1.92,11.9,;1.23,15.47,;.71,16.91,;-.8,17.19,;1.71,18.09,;3.23,17.81,;4.22,18.98,;3.86,20.47,;5.17,21.28,;6.35,20.29,;5.76,18.87,;1.2,19.53,;-.32,19.81,;-1.32,18.64,;-.84,21.27,;-2.31,21.71,;-2.36,23.25,;-.91,23.76,;-.47,25.24,;.03,22.54,;5.4,-.22,;4.4,-1.4,;6.91,-.5,;7.43,-1.95,;6.43,-3.13,;6.95,-4.58,;5.95,-5.75,;6.47,-7.2,;5.47,-8.37,;5.99,-9.82,;3.96,-8.1,;8.95,-2.23,;9.94,-1.06,;9.46,-3.68,;8.6,-4.96,;9.54,-6.18,;10.99,-5.66,;10.95,-4.12,;12.17,-3.18,;13.59,-3.77,;11.96,-1.66,)| Show InChI InChI=1S/C53H72N16O12/c1-28(2)19-37(48(77)64-36(9-5-17-58-53(55)56)52(81)69-18-6-10-42(69)45(54)74)63-44(73)25-59-46(75)38(20-29-11-13-33(71)14-12-29)65-51(80)41(26-70)68-50(79)39(22-31-21-30-7-3-4-8-34(30)61-31)67-49(78)40(23-32-24-57-27-60-32)66-47(76)35-15-16-43(72)62-35/h3-4,7-8,11-14,21,24,27-28,35-42,61,70-71H,5-6,9-10,15-20,22-23,25-26H2,1-2H3,(H2,54,74)(H,57,60)(H,59,75)(H,62,72)(H,63,73)(H,64,77)(H,65,80)(H,66,76)(H,67,78)(H,68,79)(H4,55,56,58)/t35-,36-,37-,38-,39-,40-,41-,42-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to monkey anterior pituitary LHRH receptor				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50067484 (3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...) Show SMILES CCOC(=O)c1cn(Cc2c(F)cccc2F)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C33H30F2N2O4S/c1-4-41-33(39)26-20-37(19-24-27(34)11-8-12-28(24)35)32-29(30(26)38)25(18-36(2)17-21-9-6-5-7-10-21)31(42-32)22-13-15-23(40-3)16-14-22/h5-16,20H,4,17-19H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50189708 ((S)-1-((S)-2-((S)-2-(2-((S)-2-((S)-2-((S)-2-((S)-3...) Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1cc2ccccc2[nH]1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(N)=O |wU:12.21,44.54,wD:30.43,4.4,54.57,63.67,24.27,77.83,(.86,.61,;2.37,.33,;2.89,-1.12,;3.37,1.5,;4.88,1.23,;5.88,2.4,;5.36,3.85,;3.85,4.13,;6.36,5.02,;5.85,6.47,;6.84,7.66,;8.36,7.37,;6.33,9.1,;7.32,10.28,;8.84,10,;9.35,8.55,;10.86,8.27,;11.86,9.45,;13.38,9.16,;11.34,10.9,;9.83,11.17,;4.81,9.39,;4.3,10.83,;5.29,12,;2.78,11.11,;1.78,9.93,;.27,10.22,;2.26,12.57,;.75,12.83,;-.25,11.67,;.23,14.29,;-1.28,14.58,;-2.28,13.4,;-3.82,13.5,;-4.4,12.09,;-5.85,11.56,;-6.12,10.06,;-4.94,9.06,;-3.5,9.58,;-3.23,11.09,;-1.92,11.9,;1.23,15.47,;.71,16.91,;-.8,17.19,;1.71,18.09,;3.23,17.81,;4.22,18.98,;3.86,20.47,;5.17,21.28,;6.35,20.29,;5.76,18.87,;1.2,19.53,;-.32,19.81,;-1.32,18.64,;-.84,21.27,;-2.31,21.71,;-2.36,23.25,;-.91,23.76,;-.47,25.24,;.03,22.54,;5.4,-.22,;4.4,-1.4,;6.91,-.5,;7.43,-1.95,;6.43,-3.13,;6.95,-4.58,;5.95,-5.75,;6.47,-7.2,;5.47,-8.37,;5.99,-9.82,;3.96,-8.1,;8.95,-2.23,;9.94,-1.06,;9.46,-3.68,;8.6,-4.96,;9.54,-6.18,;10.99,-5.66,;10.95,-4.12,;12.17,-3.18,;13.59,-3.77,;11.96,-1.66,)| Show InChI InChI=1S/C53H72N16O12/c1-28(2)19-37(48(77)64-36(9-5-17-58-53(55)56)52(81)69-18-6-10-42(69)45(54)74)63-44(73)25-59-46(75)38(20-29-11-13-33(71)14-12-29)65-51(80)41(26-70)68-50(79)39(22-31-21-30-7-3-4-8-34(30)61-31)67-49(78)40(23-32-24-57-27-60-32)66-47(76)35-15-16-43(72)62-35/h3-4,7-8,11-14,21,24,27-28,35-42,61,70-71H,5-6,9-10,15-20,22-23,25-26H2,1-2H3,(H2,54,74)(H,57,60)(H,59,75)(H,62,72)(H,63,73)(H,64,77)(H,65,80)(H,66,76)(H,67,78)(H,68,79)(H4,55,56,58)/t35-,36-,37-,38-,39-,40-,41-,42-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to rat anterior pituitary LHRH receptor				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189738 (3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobe...) Show SMILES CCC(=O)Nc1ccc(cc1)-c1sc2n(Cc3c(F)cccc3F)cc(C(=O)NC(C)C)c(=O)c2c1CN(C)Cc1ccccc1 Show InChI InChI=1S/C36H36F2N4O3S/c1-5-31(43)40-25-16-14-24(15-17-25)34-27(19-41(4)18-23-10-7-6-8-11-23)32-33(44)28(35(45)39-22(2)3)21-42(36(32)46-34)20-26-29(37)12-9-13-30(26)38/h6-17,21-22H,5,18-20H2,1-4H3,(H,39,45)(H,40,43)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189714 (2-[4-(2-aminoacetamido)phenyl]-3-(N-benzyl-N-methy...) Show SMILES CC(C)C(=O)c1cn(Cc2c(F)cccc2F)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(NC(=O)CN)cc1 Show InChI InChI=1S/C35H34F2N4O3S/c1-21(2)32(43)27-20-41(19-25-28(36)10-7-11-29(25)37)35-31(33(27)44)26(18-40(3)17-22-8-5-4-6-9-22)34(45-35)23-12-14-24(15-13-23)39-30(42)16-38/h4-15,20-21H,16-19,38H2,1-3H3,(H,39,42)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189708 ((S)-1-((S)-2-((S)-2-(2-((S)-2-((S)-2-((S)-2-((S)-3...) Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1cc2ccccc2[nH]1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(N)=O |wU:12.21,44.54,wD:30.43,4.4,54.57,63.67,24.27,77.83,(.86,.61,;2.37,.33,;2.89,-1.12,;3.37,1.5,;4.88,1.23,;5.88,2.4,;5.36,3.85,;3.85,4.13,;6.36,5.02,;5.85,6.47,;6.84,7.66,;8.36,7.37,;6.33,9.1,;7.32,10.28,;8.84,10,;9.35,8.55,;10.86,8.27,;11.86,9.45,;13.38,9.16,;11.34,10.9,;9.83,11.17,;4.81,9.39,;4.3,10.83,;5.29,12,;2.78,11.11,;1.78,9.93,;.27,10.22,;2.26,12.57,;.75,12.83,;-.25,11.67,;.23,14.29,;-1.28,14.58,;-2.28,13.4,;-3.82,13.5,;-4.4,12.09,;-5.85,11.56,;-6.12,10.06,;-4.94,9.06,;-3.5,9.58,;-3.23,11.09,;-1.92,11.9,;1.23,15.47,;.71,16.91,;-.8,17.19,;1.71,18.09,;3.23,17.81,;4.22,18.98,;3.86,20.47,;5.17,21.28,;6.35,20.29,;5.76,18.87,;1.2,19.53,;-.32,19.81,;-1.32,18.64,;-.84,21.27,;-2.31,21.71,;-2.36,23.25,;-.91,23.76,;-.47,25.24,;.03,22.54,;5.4,-.22,;4.4,-1.4,;6.91,-.5,;7.43,-1.95,;6.43,-3.13,;6.95,-4.58,;5.95,-5.75,;6.47,-7.2,;5.47,-8.37,;5.99,-9.82,;3.96,-8.1,;8.95,-2.23,;9.94,-1.06,;9.46,-3.68,;8.6,-4.96,;9.54,-6.18,;10.99,-5.66,;10.95,-4.12,;12.17,-3.18,;13.59,-3.77,;11.96,-1.66,)| Show InChI InChI=1S/C53H72N16O12/c1-28(2)19-37(48(77)64-36(9-5-17-58-53(55)56)52(81)69-18-6-10-42(69)45(54)74)63-44(73)25-59-46(75)38(20-29-11-13-33(71)14-12-29)65-51(80)41(26-70)68-50(79)39(22-31-21-30-7-3-4-8-34(30)61-31)67-49(78)40(23-32-24-57-27-60-32)66-47(76)35-15-16-43(72)62-35/h3-4,7-8,11-14,21,24,27-28,35-42,61,70-71H,5-6,9-10,15-20,22-23,25-26H2,1-2H3,(H2,54,74)(H,57,60)(H,59,75)(H,62,72)(H,63,73)(H,64,77)(H,65,80)(H,66,76)(H,67,78)(H,68,79)(H4,55,56,58)/t35-,36-,37-,38-,39-,40-,41-,42-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189701 (3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobe...) Show SMILES CCC(O)C(=O)Nc1ccc(cc1)-c1sc2n(Cc3c(F)cccc3F)cc(C(=O)C(C)C)c(=O)c2c1CN(C)Cc1ccccc1 Show InChI InChI=1S/C37H37F2N3O4S/c1-5-31(43)36(46)40-25-16-14-24(15-17-25)35-27(19-41(4)18-23-10-7-6-8-11-23)32-34(45)28(33(44)22(2)3)21-42(37(32)47-35)20-26-29(38)12-9-13-30(26)39/h6-17,21-22,31,43H,5,18-20H2,1-4H3,(H,40,46)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of LHRH-stimulated arachidonic acid release in CHO cells expressing monkey LHRH receptor				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189706 (CHEMBL210277 | ethyl 7-(2-fluorobenzyl)-3-((benzyl...) Show SMILES CCOC(=O)c1cn(Cc2ccccc2F)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C33H31FN2O4S/c1-4-40-33(38)27-21-36(19-24-12-8-9-13-28(24)34)32-29(30(27)37)26(20-35(2)18-22-10-6-5-7-11-22)31(41-32)23-14-16-25(39-3)17-15-23/h5-17,21H,4,18-20H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189706 (CHEMBL210277 | ethyl 7-(2-fluorobenzyl)-3-((benzyl...) Show SMILES CCOC(=O)c1cn(Cc2ccccc2F)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C33H31FN2O4S/c1-4-40-33(38)27-21-36(19-24-12-8-9-13-28(24)34)32-29(30(27)37)26(20-35(2)18-22-10-6-5-7-11-22)31(41-32)23-14-16-25(39-3)17-15-23/h5-17,21H,4,18-20H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189700 (CHEMBL210295 | ethyl 7-benzyl-3-((benzyl(methyl)am...) Show SMILES CCOC(=O)c1cn(Cc2ccccc2)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(NC(=O)Nc2ccccc2)cc1 Show InChI InChI=1S/C39H36N4O4S/c1-3-47-38(45)33-26-43(24-28-15-9-5-10-16-28)37-34(35(33)44)32(25-42(2)23-27-13-7-4-8-14-27)36(48-37)29-19-21-31(22-20-29)41-39(46)40-30-17-11-6-12-18-30/h4-22,26H,3,23-25H2,1-2H3,(H2,40,41,46)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189724 (CHEMBL211808 | ethyl 2-(4-aminophenyl)-3-(N-benzyl...) Show SMILES CCOC(=O)c1cn(Cc2ccccc2)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(N)cc1 Show InChI InChI=1S/C32H31N3O3S/c1-3-38-32(37)27-21-35(19-23-12-8-5-9-13-23)31-28(29(27)36)26(20-34(2)18-22-10-6-4-7-11-22)30(39-31)24-14-16-25(33)17-15-24/h4-17,21H,3,18-20,33H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50067485 (3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...) Show SMILES CC(C)OC(=O)c1cn(Cc2c(F)cccc2F)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(NC(=O)C(C)C)cc1 Show InChI InChI=1S/C37H37F2N3O4S/c1-22(2)35(44)40-26-16-14-25(15-17-26)34-28(19-41(5)18-24-10-7-6-8-11-24)32-33(43)29(37(45)46-23(3)4)21-42(36(32)47-34)20-27-30(38)12-9-13-31(27)39/h6-17,21-23H,18-20H2,1-5H3,(H,40,44)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to rat anterior pituitary LHRH receptor				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50067487 (3-[(Benzyl-methyl-amino)-methyl]-7-(2-methoxy-benz...) Show SMILES CCOC(=O)c1cn(Cc2ccccc2OC)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C34H34N2O5S/c1-5-41-34(38)28-22-36(20-25-13-9-10-14-29(25)40-4)33-30(31(28)37)27(21-35(2)19-23-11-7-6-8-12-23)32(42-33)24-15-17-26(39-3)18-16-24/h6-18,22H,5,19-21H2,1-4H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189709 (CHEMBL211588 | ethyl 7-(2-cyanobenzyl)-3-((benzyl(...) Show SMILES CCOC(=O)c1cn(Cc2ccccc2C#N)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C34H31N3O4S/c1-4-41-34(39)29-22-37(20-26-13-9-8-12-25(26)18-35)33-30(31(29)38)28(21-36(2)19-23-10-6-5-7-11-23)32(42-33)24-14-16-27(40-3)17-15-24/h5-17,22H,4,19-21H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189718 (CHEMBL206964 | ethyl 7-(2-nitrobenzyl)-3-((benzyl(...) Show SMILES CCOC(=O)c1cn(Cc2ccccc2[N+]([O-])=O)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C33H31N3O6S/c1-4-42-33(38)27-21-35(19-24-12-8-9-13-28(24)36(39)40)32-29(30(27)37)26(20-34(2)18-22-10-6-5-7-11-22)31(43-32)23-14-16-25(41-3)17-15-23/h5-17,21H,4,18-20H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50189701 (3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobe...) Show SMILES CCC(O)C(=O)Nc1ccc(cc1)-c1sc2n(Cc3c(F)cccc3F)cc(C(=O)C(C)C)c(=O)c2c1CN(C)Cc1ccccc1 Show InChI InChI=1S/C37H37F2N3O4S/c1-5-31(43)36(46)40-25-16-14-24(15-17-25)35-27(19-41(4)18-23-10-7-6-8-11-23)32-34(45)28(33(44)22(2)3)21-42(37(32)47-35)20-26-29(38)12-9-13-30(26)39/h6-17,21-22,31,43H,5,18-20H2,1-4H3,(H,40,46)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to rat anterior pituitary LHRH receptor				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189737 (CHEMBL212207 | ethyl 7-(2-methoxybenzyl)-3-((benzy...) Show SMILES CCOC(=O)c1cn(Cc2ccccc2OC)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccccc1 Show InChI InChI=1S/C33H32N2O4S/c1-4-39-33(37)27-22-35(20-25-17-11-12-18-28(25)38-3)32-29(30(27)36)26(31(40-32)24-15-9-6-10-16-24)21-34(2)19-23-13-7-5-8-14-23/h5-18,22H,4,19-21H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50189704 (3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobe...) Show SMILES CNC(=O)Nc1ccc(cc1)-c1sc2n(Cc3c(F)cccc3F)cc(C(=O)C(C)C)c(=O)c2c1CN(C)Cc1ccccc1 Show InChI InChI=1S/C35H34F2N4O3S/c1-21(2)31(42)27-20-41(19-25-28(36)11-8-12-29(25)37)34-30(32(27)43)26(18-40(4)17-22-9-6-5-7-10-22)33(45-34)23-13-15-24(16-14-23)39-35(44)38-3/h5-16,20-21H,17-19H2,1-4H3,(H2,38,39,44)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to rat anterior pituitary LHRH receptor				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189702 (CHEMBL212051 | ethyl 7-benzyl-3-((benzyl(methyl)am...) Show SMILES CCOC(=O)c1cn(Cc2ccccc2)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C33H32N2O4S/c1-4-39-33(37)28-22-35(20-24-13-9-6-10-14-24)32-29(30(28)36)27(21-34(2)19-23-11-7-5-8-12-23)31(40-32)25-15-17-26(38-3)18-16-25/h5-18,22H,4,19-21H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189722 (CHEMBL378845 | ethyl 7-(3-fluorobenzyl)-3-((benzyl...) Show SMILES CCOC(=O)c1cn(Cc2cccc(F)c2)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C33H31FN2O4S/c1-4-40-33(38)28-21-36(19-23-11-8-12-25(34)17-23)32-29(30(28)37)27(20-35(2)18-22-9-6-5-7-10-22)31(41-32)24-13-15-26(39-3)16-14-24/h5-17,21H,4,18-20H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189710 (CHEMBL378654 | ethyl 7-(4-methoxybenzyl)-3-((benzy...) Show SMILES CCOC(=O)c1cn(Cc2ccc(OC)cc2)c2sc(c(CN(C)Cc3ccccc3)c2c1=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C34H34N2O5S/c1-5-41-34(38)29-22-36(20-24-11-15-26(39-3)16-12-24)33-30(31(29)37)28(21-35(2)19-23-9-7-6-8-10-23)32(42-33)25-13-17-27(40-4)18-14-25/h6-18,22H,5,19-21H2,1-4H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50189735 (CHEMBL212472 | ethyl 7-(2-methoxybenzyl)-3-((benzy...) Show SMILES CCOC(=O)c1cn(Cc2ccccc2OC)c2sc(c(CN(CC)Cc3ccccc3)c2c1=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C35H36N2O5S/c1-5-36(20-24-12-8-7-9-13-24)22-28-31-32(38)29(35(39)42-6-2)23-37(21-26-14-10-11-15-30(26)41-4)34(31)43-33(28)25-16-18-27(40-3)19-17-25/h7-19,23H,5-6,20-22H2,1-4H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cells				J Med Chem 49: 3809-25 (2006) Article DOI: 10.1021/jm0512894 BindingDB Entry DOI: 10.7270/Q2VQ33G8
					More data for this Ligand-Target Pair

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