BindingDB PrimarySearch

Found 17 hits Enz. Inhib. hit(s) with all data for entry = 50037798
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50241111 (3-(2-Amino-4-fluoro-phenylamino)-6H-dibenzo[b,e]ox...) Show SMILES Nc1cc(F)ccc1Nc1ccc2c(OCc3ccccc3C2=O)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universit£t Curated by ChEMBL					Assay Description Inhibition of p38 alpha				J Med Chem 49: 7912-5 (2006) Article DOI: 10.1021/jm061072p BindingDB Entry DOI: 10.7270/Q26Q1Z2K
Eberhard-Karls-Universit£t Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM13336 (4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universit£t Curated by ChEMBL					Assay Description Inhibition of p38 alpha				J Med Chem 49: 7912-5 (2006) Article DOI: 10.1021/jm061072p BindingDB Entry DOI: 10.7270/Q26Q1Z2K
Eberhard-Karls-Universit£t Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM13533 (1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universit£t Curated by ChEMBL					Assay Description Inhibition of p38 alpha				J Med Chem 49: 7912-5 (2006) Article DOI: 10.1021/jm061072p BindingDB Entry DOI: 10.7270/Q26Q1Z2K
Eberhard-Karls-Universit£t Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50241112 (2-(2-Amino-phenylamino)-10,11-dihydro-dibenzo[a,d]...) Show SMILES Nc1ccccc1Nc1ccc2c(CCc3ccccc3C2=O)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	104	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universit£t Curated by ChEMBL					Assay Description Inhibition of p38 alpha				J Med Chem 49: 7912-5 (2006) Article DOI: 10.1021/jm061072p BindingDB Entry DOI: 10.7270/Q26Q1Z2K
Eberhard-Karls-Universit£t Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50136897 ((2-Chloro-4-phenylamino-phenyl)-o-tolyl-methanone ...) Show SMILES Cc1ccccc1C(=O)c1ccc(Nc2ccccc2)cc1Cl Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universit£t Curated by ChEMBL					Assay Description Inhibition of p38 alpha				J Med Chem 49: 7912-5 (2006) Article DOI: 10.1021/jm061072p BindingDB Entry DOI: 10.7270/Q26Q1Z2K
Eberhard-Karls-Universit£t Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50370778 (CHEMBL220074) Show SMILES Nc1ccccc1Nc1ccc2c(SCc3ccccc3C2=O)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	196	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universit£t Curated by ChEMBL					Assay Description Inhibition of p38 alpha				J Med Chem 49: 7912-5 (2006) Article DOI: 10.1021/jm061072p BindingDB Entry DOI: 10.7270/Q26Q1Z2K
Eberhard-Karls-Universit£t Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50241114 (3-(2,4-Difluoro-phenylamino)-6H-dibenzo[b,e]oxepin...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	239	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universit£t Curated by ChEMBL					Assay Description Inhibition of p38 alpha				J Med Chem 49: 7912-5 (2006) Article DOI: 10.1021/jm061072p BindingDB Entry DOI: 10.7270/Q26Q1Z2K
Eberhard-Karls-Universit£t Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50241115 (3-(2-Amino-phenylamino)-6H-dibenzo[b,e]oxepin-11-o...) Show SMILES Nc1ccccc1Nc1ccc2c(OCc3ccccc3C2=O)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	303	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universit£t Curated by ChEMBL					Assay Description Inhibition of p38 alpha				J Med Chem 49: 7912-5 (2006) Article DOI: 10.1021/jm061072p BindingDB Entry DOI: 10.7270/Q26Q1Z2K
Eberhard-Karls-Universit£t Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50241113 (2-(2-amino-phenylamino)-dibenzo[a,d]cyclohepten-5-...) Show SMILES Nc1ccccc1Nc1ccc2c(c1)ccc1ccccc1c2=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universit£t Curated by ChEMBL					Assay Description Inhibition of p38 alpha				J Med Chem 49: 7912-5 (2006) Article DOI: 10.1021/jm061072p BindingDB Entry DOI: 10.7270/Q26Q1Z2K
Eberhard-Karls-Universit£t Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50370774 (CHEMBL219692) Show SMILES Nc1ccc(Nc2ccc3c(CCc4ccccc4C3=O)c2)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universit£t Curated by ChEMBL					Assay Description Inhibition of p38 alpha				J Med Chem 49: 7912-5 (2006) Article DOI: 10.1021/jm061072p BindingDB Entry DOI: 10.7270/Q26Q1Z2K
Eberhard-Karls-Universit£t Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50370776 (CHEMBL373775) Show SMILES Nc1cccc(Nc2ccc3c(OCc4ccccc4C3=O)c2)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universit£t Curated by ChEMBL					Assay Description Inhibition of p38 alpha				J Med Chem 49: 7912-5 (2006) Article DOI: 10.1021/jm061072p BindingDB Entry DOI: 10.7270/Q26Q1Z2K
Eberhard-Karls-Universit£t Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50370770 (CHEMBL219424) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universit£t Curated by ChEMBL					Assay Description Inhibition of p38 alpha				J Med Chem 49: 7912-5 (2006) Article DOI: 10.1021/jm061072p BindingDB Entry DOI: 10.7270/Q26Q1Z2K
Eberhard-Karls-Universit£t Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50370777 (CHEMBL375350) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universit£t Curated by ChEMBL					Assay Description Inhibition of p38 alpha				J Med Chem 49: 7912-5 (2006) Article DOI: 10.1021/jm061072p BindingDB Entry DOI: 10.7270/Q26Q1Z2K
Eberhard-Karls-Universit£t Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50370775 (CHEMBL219259) Show SMILES Nc1ccccc1Nc1ccc2c(COc3ccccc3C2=O)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universit£t Curated by ChEMBL					Assay Description Inhibition of p38 alpha				J Med Chem 49: 7912-5 (2006) Article DOI: 10.1021/jm061072p BindingDB Entry DOI: 10.7270/Q26Q1Z2K
Eberhard-Karls-Universit£t Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50370772 (CHEMBL220349) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universit£t Curated by ChEMBL					Assay Description Inhibition of p38 alpha				J Med Chem 49: 7912-5 (2006) Article DOI: 10.1021/jm061072p BindingDB Entry DOI: 10.7270/Q26Q1Z2K
Eberhard-Karls-Universit£t Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50370771 (CHEMBL219965) Show SMILES Nc1ccc(Nc2ccc3c(OCc4ccccc4C3=O)c2)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universit£t Curated by ChEMBL					Assay Description Inhibition of p38 alpha				J Med Chem 49: 7912-5 (2006) Article DOI: 10.1021/jm061072p BindingDB Entry DOI: 10.7270/Q26Q1Z2K
Eberhard-Karls-Universit£t Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50370773 (CHEMBL219476) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universit£t Curated by ChEMBL					Assay Description Inhibition of p38 alpha				J Med Chem 49: 7912-5 (2006) Article DOI: 10.1021/jm061072p BindingDB Entry DOI: 10.7270/Q26Q1Z2K
Eberhard-Karls-Universit£t Curated by ChEMBL					More data for this Ligand-Target Pair