Compile Data Set for Download or QSAR

Found 136 hits Enz. Inhib. hit(s) with all data for entry = 50038322   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374829 (CHEMBL255629) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2c(Cl)cccc2Cl)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H23Cl3N2O3S/c21-16-7-5-15(6-8-16)20(26)9-13-25(14-10-20)12-2-11-24-29(27,28)19-17(22)3-1-4-18(19)23/h1,3-8,24,26H,2,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374816 (CHEMBL256404) Show SMILES Cc1ccccc1S(=O)(=O)NCCCN1CCC(O)(CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H27ClN2O3S/c1-17-5-2-3-6-20(17)28(26,27)23-13-4-14-24-15-11-21(25,12-16-24)18-7-9-19(22)10-8-18/h2-3,5-10,23,25H,4,11-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374831 (CHEMBL429419) Show SMILES Cc1cccc(Cl)c1S(=O)(=O)NCCCN1CCC(O)(CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H26Cl2N2O3S/c1-16-4-2-5-19(23)20(16)29(27,28)24-12-3-13-25-14-10-21(26,11-15-25)17-6-8-18(22)9-7-17/h2,4-9,24,26H,3,10-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374806 (CHEMBL269957) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2ccccc2Cl)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H24Cl2N2O3S/c21-17-8-6-16(7-9-17)20(25)10-14-24(15-11-20)13-3-12-23-28(26,27)19-5-2-1-4-18(19)22/h1-2,4-9,23,25H,3,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374818 (CHEMBL258065) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2ccccc2C(F)(F)F)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H24ClF3N2O3S/c22-17-8-6-16(7-9-17)20(28)10-14-27(15-11-20)13-3-12-26-31(29,30)19-5-2-1-4-18(19)21(23,24)25/h1-2,4-9,26,28H,3,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374807 (CHEMBL272097) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2cccs2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H23ClN2O3S2/c19-16-6-4-15(5-7-16)18(22)8-12-21(13-9-18)11-2-10-20-26(23,24)17-3-1-14-25-17/h1,3-7,14,20,22H,2,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374814 (CHEMBL256888) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2ccccc2F)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H24ClFN2O3S/c21-17-8-6-16(7-9-17)20(25)10-14-24(15-11-20)13-3-12-23-28(26,27)19-5-2-1-4-18(19)22/h1-2,4-9,23,25H,3,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374829 (CHEMBL255629) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2c(Cl)cccc2Cl)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H23Cl3N2O3S/c21-16-7-5-15(6-8-16)20(26)9-13-25(14-10-20)12-2-11-24-29(27,28)19-17(22)3-1-4-18(19)23/h1,3-8,24,26H,2,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]MIP1-alpha from human CCR1 receptor expressed in THP1 cells				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374808 (CHEMBL272523) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2ccccc2-c2ccccc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C26H29ClN2O3S/c27-23-13-11-22(12-14-23)26(30)15-19-29(20-16-26)18-6-17-28-33(31,32)25-10-5-4-9-24(25)21-7-2-1-3-8-21/h1-5,7-14,28,30H,6,15-20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374804 (CHEMBL270631) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2ccccc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H25ClN2O3S/c21-18-9-7-17(8-10-18)20(24)11-15-23(16-12-20)14-4-13-22-27(25,26)19-5-2-1-3-6-19/h1-3,5-10,22,24H,4,11-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374831 (CHEMBL429419) Show SMILES Cc1cccc(Cl)c1S(=O)(=O)NCCCN1CCC(O)(CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H26Cl2N2O3S/c1-16-4-2-5-19(23)20(16)29(27,28)24-12-3-13-25-14-10-21(26,11-15-25)17-6-8-18(22)9-7-17/h2,4-9,24,26H,3,10-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]MIP1-alpha from human CCR1 receptor expressed in THP1 cells				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374837 (CHEMBL403728) Show SMILES OC1(CCN(CC1)C1CCN(CC1)S(=O)(=O)c1ccccc1Br)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H26BrClN2O3S/c23-20-3-1-2-4-21(20)30(28,29)26-13-9-19(10-14-26)25-15-11-22(27,12-16-25)17-5-7-18(24)8-6-17/h1-8,19,27H,9-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]MIP1-alpha from human CCR1 receptor expressed in THP1 cells				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374837 (CHEMBL403728) Show SMILES OC1(CCN(CC1)C1CCN(CC1)S(=O)(=O)c1ccccc1Br)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H26BrClN2O3S/c23-20-3-1-2-4-21(20)30(28,29)26-13-9-19(10-14-26)25-15-11-22(27,12-16-25)17-5-7-18(24)8-6-17/h1-8,19,27H,9-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374830 (CHEMBL257509) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2ccc(F)cc2Cl)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H23Cl2FN2O3S/c21-16-4-2-15(3-5-16)20(26)8-12-25(13-9-20)11-1-10-24-29(27,28)19-7-6-17(23)14-18(19)22/h2-7,14,24,26H,1,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374812 (CHEMBL256821) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2cccc(Cl)c2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H24Cl2N2O3S/c21-17-7-5-16(6-8-17)20(25)9-13-24(14-10-20)12-2-11-23-28(26,27)19-4-1-3-18(22)15-19/h1,3-8,15,23,25H,2,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374823 (CHEMBL255338) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2ccccc2-c2ccsc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C24H27ClN2O3S2/c25-21-8-6-20(7-9-21)24(28)11-15-27(16-12-24)14-3-13-26-32(29,30)23-5-2-1-4-22(23)19-10-17-31-18-19/h1-2,4-10,17-18,26,28H,3,11-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374806 (CHEMBL269957) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2ccccc2Cl)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H24Cl2N2O3S/c21-17-8-6-16(7-9-17)20(25)10-14-24(15-11-20)13-3-12-23-28(26,27)19-5-2-1-4-18(19)22/h1-2,4-9,23,25H,3,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]MIP1-alpha from human CCR1 receptor expressed in THP1 cells				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374846 (CHEMBL256272) Show SMILES CC1CC(CCN1S(=O)(=O)c1ccccc1Br)N1CCC(O)(CC1)c1ccc(Cl)cc1 |w:3.18,1.0| Show InChI InChI=1S/C23H28BrClN2O3S/c1-17-16-20(10-13-27(17)31(29,30)22-5-3-2-4-21(22)24)26-14-11-23(28,12-15-26)18-6-8-19(25)9-7-18/h2-9,17,20,28H,10-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374817 (CHEMBL258064) Show SMILES Cc1ccc(cc1)S(=O)(=O)NCCCN1CCC(O)(CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H27ClN2O3S/c1-17-3-9-20(10-4-17)28(26,27)23-13-2-14-24-15-11-21(25,12-16-24)18-5-7-19(22)8-6-18/h3-10,23,25H,2,11-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374855 (CHEMBL404465) Show SMILES OC1(CCCN(CC1)C1CCN(CC1)S(=O)(=O)c1ccccc1Cl)c1ccc(Cl)cc1 |w:1.0| Show InChI InChI=1S/C23H28Cl2N2O3S/c24-19-8-6-18(7-9-19)23(28)12-3-14-26(17-13-23)20-10-15-27(16-11-20)31(29,30)22-5-2-1-4-21(22)25/h1-2,4-9,20,28H,3,10-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374833 (CHEMBL270253) Show SMILES OC1(CCN(CC1)C1CCN(CC1)S(=O)(=O)c1ccccc1Cl)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H26Cl2N2O3S/c23-18-7-5-17(6-8-18)22(27)11-15-25(16-12-22)19-9-13-26(14-10-19)30(28,29)21-4-2-1-3-20(21)24/h1-8,19,27H,9-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374805 (CHEMBL429591) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2ccccc2Br)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H24BrClN2O3S/c21-18-4-1-2-5-19(18)28(26,27)23-12-3-13-24-14-10-20(25,11-15-24)16-6-8-17(22)9-7-16/h1-2,4-9,23,25H,3,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]MIP1-alpha from human CCR1 receptor expressed in THP1 cells				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374816 (CHEMBL256404) Show SMILES Cc1ccccc1S(=O)(=O)NCCCN1CCC(O)(CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H27ClN2O3S/c1-17-5-2-3-6-20(17)28(26,27)23-13-4-14-24-15-11-21(25,12-16-24)18-7-9-19(22)10-8-18/h2-3,5-10,23,25H,4,11-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]MIP1-alpha from human CCR1 receptor expressed in THP1 cells				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374807 (CHEMBL272097) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2cccs2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H23ClN2O3S2/c19-16-6-4-15(5-7-16)18(22)8-12-21(13-9-18)11-2-10-20-26(23,24)17-3-1-14-25-17/h1,3-7,14,20,22H,2,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]MIP1-alpha from human CCR1 receptor expressed in THP1 cells				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374860 (CHEMBL258359) Show SMILES OC1(CCN(CC1)C1CCN(CC1)S(=O)(=O)c1ccccc1Cl)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C22H25Cl3N2O3S/c23-18-6-5-16(15-20(18)25)22(28)9-13-26(14-10-22)17-7-11-27(12-8-17)31(29,30)21-4-2-1-3-19(21)24/h1-6,15,17,28H,7-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374858 (CHEMBL271903) Show SMILES OC1(CCN(CC1)C1CCN(CC1)S(=O)(=O)c1ccccc1Cl)c1ccc(Br)cc1 Show InChI InChI=1S/C22H26BrClN2O3S/c23-18-7-5-17(6-8-18)22(27)11-15-25(16-12-22)19-9-13-26(14-10-19)30(28,29)21-4-2-1-3-20(21)24/h1-8,19,27H,9-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374835 (CHEMBL404033) Show SMILES Cc1ccccc1S(=O)(=O)N1CCC(CC1)N1CCC(O)(CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H29ClN2O3S/c1-18-4-2-3-5-22(18)30(28,29)26-14-10-21(11-15-26)25-16-12-23(27,13-17-25)19-6-8-20(24)9-7-19/h2-9,21,27H,10-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374866 (CHEMBL270433) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2cccc3ccccc23)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C24H27ClN2O3S/c25-21-11-9-20(10-12-21)24(28)13-17-27(18-14-24)16-4-15-26-31(29,30)23-8-3-6-19-5-1-2-7-22(19)23/h1-3,5-12,26,28H,4,13-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374819 (CHEMBL258361) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2ccccc2OC(F)(F)F)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H24ClF3N2O4S/c22-17-8-6-16(7-9-17)20(28)10-14-27(15-11-20)13-3-12-26-32(29,30)19-5-2-1-4-18(19)31-21(23,24)25/h1-2,4-9,26,28H,3,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374833 (CHEMBL270253) Show SMILES OC1(CCN(CC1)C1CCN(CC1)S(=O)(=O)c1ccccc1Cl)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H26Cl2N2O3S/c23-18-7-5-17(6-8-18)22(27)11-15-25(16-12-22)19-9-13-26(14-10-19)30(28,29)21-4-2-1-3-20(21)24/h1-8,19,27H,9-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]MIP1-alpha from human CCR1 receptor expressed in THP1 cells				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374815 (CHEMBL256889) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H24ClFN2O3S/c21-17-4-2-16(3-5-17)20(25)10-14-24(15-11-20)13-1-12-23-28(26,27)19-8-6-18(22)7-9-19/h2-9,23,25H,1,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374846 (CHEMBL256272) Show SMILES CC1CC(CCN1S(=O)(=O)c1ccccc1Br)N1CCC(O)(CC1)c1ccc(Cl)cc1 |w:3.18,1.0| Show InChI InChI=1S/C23H28BrClN2O3S/c1-17-16-20(10-13-27(17)31(29,30)22-5-3-2-4-21(22)24)26-14-11-23(28,12-15-26)18-6-8-19(25)9-7-18/h2-9,17,20,28H,10-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]MIP1-alpha from human CCR1 receptor expressed in THP1 cells				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374822 (CHEMBL257452) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2ccccc2-c2cccs2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C24H27ClN2O3S2/c25-20-10-8-19(9-11-20)24(28)12-16-27(17-13-24)15-4-14-26-32(29,30)23-7-2-1-5-21(23)22-6-3-18-31-22/h1-3,5-11,18,26,28H,4,12-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374822 (CHEMBL257452) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2ccccc2-c2cccs2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C24H27ClN2O3S2/c25-20-10-8-19(9-11-20)24(28)12-16-27(17-13-24)15-4-14-26-32(29,30)23-7-2-1-5-21(23)22-6-3-18-31-22/h1-3,5-11,18,26,28H,4,12-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]MIP1-alpha from human CCR1 receptor expressed in THP1 cells				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374818 (CHEMBL258065) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2ccccc2C(F)(F)F)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H24ClF3N2O3S/c22-17-8-6-16(7-9-17)20(28)10-14-27(15-11-20)13-3-12-26-31(29,30)19-5-2-1-4-18(19)21(23,24)25/h1-2,4-9,26,28H,3,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]MIP1-alpha from human CCR1 receptor expressed in THP1 cells				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374847 (CHEMBL402827) Show SMILES Cc1cccc(Cl)c1S(=O)(=O)N1CCC[C@H](C1)N1CCC(O)(CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H28Cl2N2O3S/c1-17-4-2-6-21(25)22(17)31(29,30)27-13-3-5-20(16-27)26-14-11-23(28,12-15-26)18-7-9-19(24)10-8-18/h2,4,6-10,20,28H,3,5,11-16H2,1H3/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374826 (CHEMBL270863) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2cc(Cl)ccc2Cl)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H23Cl3N2O3S/c21-16-4-2-15(3-5-16)20(26)8-12-25(13-9-20)11-1-10-24-29(27,28)19-14-17(22)6-7-18(19)23/h2-7,14,24,26H,1,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374845 (CHEMBL256271) Show SMILES CC1CC(CCN1S(=O)(=O)c1ccccc1Cl)N1CCC(O)(CC1)c1ccc(Cl)cc1 |w:3.18,1.0| Show InChI InChI=1S/C23H28Cl2N2O3S/c1-17-16-20(10-13-27(17)31(29,30)22-5-3-2-4-21(22)25)26-14-11-23(28,12-15-26)18-6-8-19(24)9-7-18/h2-9,17,20,28H,10-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374804 (CHEMBL270631) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2ccccc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H25ClN2O3S/c21-18-9-7-17(8-10-18)20(24)11-15-23(16-12-20)14-4-13-22-27(25,26)19-5-2-1-3-6-19/h1-3,5-10,22,24H,4,11-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]MIP1-alpha from human CCR1 receptor expressed in THP1 cells				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374845 (CHEMBL256271) Show SMILES CC1CC(CCN1S(=O)(=O)c1ccccc1Cl)N1CCC(O)(CC1)c1ccc(Cl)cc1 |w:3.18,1.0| Show InChI InChI=1S/C23H28Cl2N2O3S/c1-17-16-20(10-13-27(17)31(29,30)22-5-3-2-4-21(22)25)26-14-11-23(28,12-15-26)18-6-8-19(24)9-7-18/h2-9,17,20,28H,10-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]MIP1-alpha from human CCR1 receptor expressed in THP1 cells				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374838 (CHEMBL256887) Show SMILES OC1(CCN(CC1)C1CCN(CC1)S(=O)(=O)c1c(F)cc(F)cc1Br)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H24BrClF2N2O3S/c23-19-13-17(25)14-20(26)21(19)32(30,31)28-9-5-18(6-10-28)27-11-7-22(29,8-12-27)15-1-3-16(24)4-2-15/h1-4,13-14,18,29H,5-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374819 (CHEMBL258361) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2ccccc2OC(F)(F)F)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H24ClF3N2O4S/c22-17-8-6-16(7-9-17)20(28)10-14-27(15-11-20)13-3-12-26-32(29,30)19-5-2-1-4-18(19)31-21(23,24)25/h1-2,4-9,26,28H,3,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]MIP1-alpha from human CCR1 receptor expressed in THP1 cells				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374823 (CHEMBL255338) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2ccccc2-c2ccsc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C24H27ClN2O3S2/c25-21-8-6-20(7-9-21)24(28)11-15-27(16-12-24)14-3-13-26-32(29,30)23-5-2-1-4-22(23)19-10-17-31-18-19/h1-2,4-10,17-18,26,28H,3,11-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]MIP1-alpha from human CCR1 receptor expressed in THP1 cells				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374824 (CHEMBL258360) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2cccc(Cl)c2Cl)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H23Cl3N2O3S/c21-16-7-5-15(6-8-16)20(26)9-13-25(14-10-20)12-2-11-24-29(27,28)18-4-1-3-17(22)19(18)23/h1,3-8,24,26H,2,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374830 (CHEMBL257509) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2ccc(F)cc2Cl)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H23Cl2FN2O3S/c21-16-4-2-15(3-5-16)20(26)8-12-25(13-9-20)11-1-10-24-29(27,28)19-7-6-17(23)14-18(19)22/h2-7,14,24,26H,1,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]MIP1-alpha from human CCR1 receptor expressed in THP1 cells				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374825 (CHEMBL411477) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2ccc(Cl)cc2Cl)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H23Cl3N2O3S/c21-16-4-2-15(3-5-16)20(26)8-12-25(13-9-20)11-1-10-24-29(27,28)19-7-6-17(22)14-18(19)23/h2-7,14,24,26H,1,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374836 (CHEMBL269956) Show SMILES Cc1cccc(Cl)c1S(=O)(=O)N1CCC(CC1)N1CCC(O)(CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H28Cl2N2O3S/c1-17-3-2-4-21(25)22(17)31(29,30)27-13-9-20(10-14-27)26-15-11-23(28,12-16-26)18-5-7-19(24)8-6-18/h2-8,20,28H,9-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]MIP1-alpha from human CCR1 receptor expressed in THP1 cells				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374813 (CHEMBL404732) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2ccc(Cl)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H24Cl2N2O3S/c21-17-4-2-16(3-5-17)20(25)10-14-24(15-11-20)13-1-12-23-28(26,27)19-8-6-18(22)7-9-19/h2-9,23,25H,1,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374812 (CHEMBL256821) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2cccc(Cl)c2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H24Cl2N2O3S/c21-17-7-5-16(6-8-17)20(25)9-13-24(14-10-20)12-2-11-23-28(26,27)19-4-1-3-18(22)15-19/h1,3-8,15,23,25H,2,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]MIP1-alpha from human CCR1 receptor expressed in THP1 cells				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374821 (CHEMBL270564) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2ccsc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H23ClN2O3S2/c19-16-4-2-15(3-5-16)18(22)7-11-21(12-8-18)10-1-9-20-26(23,24)17-6-13-25-14-17/h2-6,13-14,20,22H,1,7-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	385	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair

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