Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lethal factor (Bacillus anthracis) | BDBM2683 (2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Protection against Bacillus anthracis lethal toxin-mediated cytotoxicity in mouse RAW264.7 cells assessed as change in viability after 24 hrs by WST1... | Antimicrob Agents Chemother 51: 2403-11 (2007) Article DOI: 10.1128/AAC.01184-06 BindingDB Entry DOI: 10.7270/Q2765G7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lethal factor (Bacillus anthracis) | BDBM50240721 ((E)-(2S,3R)-2-Dimethylamino-octadec-4-ene-1,3-diol...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Protection against Bacillus anthracis lethal toxin-mediated cytotoxicity in mouse RAW264.7 cells assessed as change in viability after 24 hrs by WST1... | Antimicrob Agents Chemother 51: 2403-11 (2007) Article DOI: 10.1128/AAC.01184-06 BindingDB Entry DOI: 10.7270/Q2765G7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lethal factor (Bacillus anthracis) | BDBM18957 ((2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-di...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Protection against Bacillus anthracis lethal toxin-mediated cytotoxicity in mouse RAW264.7 cells assessed as change in viability after 24 hrs by WST1... | Antimicrob Agents Chemother 51: 2403-11 (2007) Article DOI: 10.1128/AAC.01184-06 BindingDB Entry DOI: 10.7270/Q2765G7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lethal factor (Bacillus anthracis) | BDBM78577 (BEPRIDIL HYDROCHLORIDE | Bepridil | MLS000028456 |...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Protection against Bacillus anthracis lethal toxin-mediated cytotoxicity in mouse RAW264.7 cells assessed as change in viability after 24 hrs by WST1... | Antimicrob Agents Chemother 51: 2403-11 (2007) Article DOI: 10.1128/AAC.01184-06 BindingDB Entry DOI: 10.7270/Q2765G7P | |||||||||||
More data for this Ligand-Target Pair |