Compile Data Set for Download or QSAR

Found 30 hits Enz. Inhib. hit(s) with all data for entry = 50039200   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321410 (CHEMBL1170780 | N-((4-phenyl-2-propyloxazol-5-yl)m...) Show SMILES CCCc1nc(c(CNCCCN2CCN(CC2)c2cccc(c2)C(F)(F)F)o1)-c1ccccc1 Show InChI InChI=1S/C27H33F3N4O/c1-2-8-25-32-26(21-9-4-3-5-10-21)24(35-25)20-31-13-7-14-33-15-17-34(18-16-33)23-12-6-11-22(19-23)27(28,29)30/h3-6,9-12,19,31H,2,7-8,13-18,20H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50117922 ((1S,2S)-2-(2-((3-(1H-benzo[d]imidazol-2-yl)propyl)...) Show SMILES COCC(=O)O[C@]1(CCN(C)CCCc2nc3ccccc3[nH]2)CCc2cc(F)ccc2[C@@H]1C(C)C |r| Show InChI InChI=1S/C29H38FN3O3/c1-20(2)28-23-12-11-22(30)18-21(23)13-14-29(28,36-27(34)19-35-4)15-17-33(3)16-7-10-26-31-24-8-5-6-9-25(24)32-26/h5-6,8-9,11-12,18,20,28H,7,10,13-17,19H2,1-4H3,(H,31,32)/t28-,29-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50117922 ((1S,2S)-2-(2-((3-(1H-benzo[d]imidazol-2-yl)propyl)...) Show SMILES COCC(=O)O[C@]1(CCN(C)CCCc2nc3ccccc3[nH]2)CCc2cc(F)ccc2[C@@H]1C(C)C |r| Show InChI InChI=1S/C29H38FN3O3/c1-20(2)28-23-12-11-22(30)18-21(23)13-14-29(28,36-27(34)19-35-4)15-17-33(3)16-7-10-26-31-24-8-5-6-9-25(24)32-26/h5-6,8-9,11-12,18,20,28H,7,10,13-17,19H2,1-4H3,(H,31,32)/t28-,29-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by manual patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321408 (CHEMBL1171952 | N-((4-phenyl-2-propyloxazol-5-yl)m...) Show SMILES CCCc1nc(c(CNCCCN2CCN(CC2)c2cccc(C)c2)o1)-c1ccccc1 Show InChI InChI=1S/C27H36N4O/c1-3-9-26-29-27(23-11-5-4-6-12-23)25(32-26)21-28-14-8-15-30-16-18-31(19-17-30)24-13-7-10-22(2)20-24/h4-7,10-13,20,28H,3,8-9,14-19,21H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321397 (CHEMBL1170810 | N-((4-phenyl-2-propyloxazol-5-yl)m...) Show SMILES CCCc1nc(c(CNCCN2CCN(CC2)c2ccc(cc2)C(F)(F)F)o1)-c1ccccc1 Show InChI InChI=1S/C26H31F3N4O/c1-2-6-24-31-25(20-7-4-3-5-8-20)23(34-24)19-30-13-14-32-15-17-33(18-16-32)22-11-9-21(10-12-22)26(27,28)29/h3-5,7-12,30H,2,6,13-19H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321406 (3-(4-(4-chlorophenyl)piperazin-1-yl)-N-((4-phenyl-...) Show SMILES CCCc1nc(c(CNCCCN2CCN(CC2)c2ccc(Cl)cc2)o1)-c1ccccc1 Show InChI InChI=1S/C26H33ClN4O/c1-2-7-25-29-26(21-8-4-3-5-9-21)24(32-25)20-28-14-6-15-30-16-18-31(19-17-30)23-12-10-22(27)11-13-23/h3-5,8-13,28H,2,6-7,14-20H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321391 (2-(4-(3-chlorophenyl)piperazin-1-yl)-N-((4-phenyl-...) Show SMILES CCCc1nc(c(CNCCN2CCN(CC2)c2cccc(Cl)c2)o1)-c1ccccc1 Show InChI InChI=1S/C25H31ClN4O/c1-2-7-24-28-25(20-8-4-3-5-9-20)23(31-24)19-27-12-13-29-14-16-30(17-15-29)22-11-6-10-21(26)18-22/h3-6,8-11,18,27H,2,7,12-17,19H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321398 (2-(4-(2,3-dimethylphenyl)piperazin-1-yl)-N-((4-phe...) Show SMILES CCCc1nc(c(CNCCN2CCN(CC2)c2cccc(C)c2C)o1)-c1ccccc1 Show InChI InChI=1S/C27H36N4O/c1-4-9-26-29-27(23-11-6-5-7-12-23)25(32-26)20-28-14-15-30-16-18-31(19-17-30)24-13-8-10-21(2)22(24)3/h5-8,10-13,28H,4,9,14-20H2,1-3H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321405 (3-(4-(3-chlorophenyl)piperazin-1-yl)-N-((4-phenyl-...) Show SMILES CCCc1nc(c(CNCCCN2CCN(CC2)c2cccc(Cl)c2)o1)-c1ccccc1 Show InChI InChI=1S/C26H33ClN4O/c1-2-8-25-29-26(21-9-4-3-5-10-21)24(32-25)20-28-13-7-14-30-15-17-31(18-16-30)23-12-6-11-22(27)19-23/h3-6,9-12,19,28H,2,7-8,13-18,20H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321412 (3-(4-(2,3-dimethylphenyl)piperazin-1-yl)-N-((4-phe...) Show SMILES CCCc1nc(c(CNCCCN2CCN(CC2)c2cccc(C)c2C)o1)-c1ccccc1 Show InChI InChI=1S/C28H38N4O/c1-4-10-27-30-28(24-12-6-5-7-13-24)26(33-27)21-29-15-9-16-31-17-19-32(20-18-31)25-14-8-11-22(2)23(25)3/h5-8,11-14,29H,4,9-10,15-21H2,1-3H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321396 (CHEMBL1171770 | N-((4-phenyl-2-propyloxazol-5-yl)m...) Show SMILES CCCc1nc(c(CNCCN2CCN(CC2)c2cccc(c2)C(F)(F)F)o1)-c1ccccc1 Show InChI InChI=1S/C26H31F3N4O/c1-2-7-24-31-25(20-8-4-3-5-9-20)23(34-24)19-30-12-13-32-14-16-33(17-15-32)22-11-6-10-21(18-22)26(27,28)29/h3-6,8-11,18,30H,2,7,12-17,19H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321395 (CHEMBL1171599 | N-((4-phenyl-2-propyloxazol-5-yl)m...) Show SMILES CCCc1nc(c(CNCCN2CCN(CC2)c2ccccc2C(F)(F)F)o1)-c1ccccc1 Show InChI InChI=1S/C26H31F3N4O/c1-2-8-24-31-25(20-9-4-3-5-10-20)23(34-24)19-30-13-14-32-15-17-33(18-16-32)22-12-7-6-11-21(22)26(27,28)29/h3-7,9-12,30H,2,8,13-19H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321399 (2-(4-(2,4-dimethylphenyl)piperazin-1-yl)-N-((4-phe...) Show SMILES CCCc1nc(c(CNCCN2CCN(CC2)c2ccc(C)cc2C)o1)-c1ccccc1 Show InChI InChI=1S/C27H36N4O/c1-4-8-26-29-27(23-9-6-5-7-10-23)25(32-26)20-28-13-14-30-15-17-31(18-16-30)24-12-11-21(2)19-22(24)3/h5-7,9-12,19,28H,4,8,13-18,20H2,1-3H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321400 (2-(4-(3,4-dimethylphenyl)piperazin-1-yl)-N-((4-phe...) Show SMILES CCCc1nc(c(CNCCN2CCN(CC2)c2ccc(C)c(C)c2)o1)-c1ccccc1 Show InChI InChI=1S/C27H36N4O/c1-4-8-26-29-27(23-9-6-5-7-10-23)25(32-26)20-28-13-14-30-15-17-31(18-16-30)24-12-11-21(2)22(3)19-24/h5-7,9-12,19,28H,4,8,13-18,20H2,1-3H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321404 (3-(4-(2-chlorophenyl)piperazin-1-yl)-N-((4-phenyl-...) Show SMILES CCCc1nc(c(CNCCCN2CCN(CC2)c2ccccc2Cl)o1)-c1ccccc1 Show InChI InChI=1S/C26H33ClN4O/c1-2-9-25-29-26(21-10-4-3-5-11-21)24(32-25)20-28-14-8-15-30-16-18-31(19-17-30)23-13-7-6-12-22(23)27/h3-7,10-13,28H,2,8-9,14-20H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321392 (2-(4-(4-chlorophenyl)piperazin-1-yl)-N-((4-phenyl-...) Show SMILES CCCc1nc(c(CNCCN2CCN(CC2)c2ccc(Cl)cc2)o1)-c1ccccc1 Show InChI InChI=1S/C25H31ClN4O/c1-2-6-24-28-25(20-7-4-3-5-8-20)23(31-24)19-27-13-14-29-15-17-30(18-16-29)22-11-9-21(26)10-12-22/h3-5,7-12,27H,2,6,13-19H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321413 (3-(4-(3,4-dimethylphenyl)piperazin-1-yl)-N-((4-phe...) Show SMILES CCCc1nc(c(CNCCCN2CCN(CC2)c2ccc(C)c(C)c2)o1)-c1ccccc1 Show InChI InChI=1S/C28H38N4O/c1-4-9-27-30-28(24-10-6-5-7-11-24)26(33-27)21-29-14-8-15-31-16-18-32(19-17-31)25-13-12-22(2)23(3)20-25/h5-7,10-13,20,29H,4,8-9,14-19,21H2,1-3H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321402 (3-(4-(3-fluorophenyl)piperazin-1-yl)-N-((4-phenyl-...) Show SMILES CCCc1nc(c(CNCCCN2CCN(CC2)c2cccc(F)c2)o1)-c1ccccc1 Show InChI InChI=1S/C26H33FN4O/c1-2-8-25-29-26(21-9-4-3-5-10-21)24(32-25)20-28-13-7-14-30-15-17-31(18-16-30)23-12-6-11-22(27)19-23/h3-6,9-12,19,28H,2,7-8,13-18,20H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321403 (3-(4-(4-fluorophenyl)piperazin-1-yl)-N-((4-phenyl-...) Show SMILES CCCc1nc(c(CNCCCN2CCN(CC2)c2ccc(F)cc2)o1)-c1ccccc1 Show InChI InChI=1S/C26H33FN4O/c1-2-7-25-29-26(21-8-4-3-5-9-21)24(32-25)20-28-14-6-15-30-16-18-31(19-17-30)23-12-10-22(27)11-13-23/h3-5,8-13,28H,2,6-7,14-20H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321388 (2-(4-(3-fluorophenyl)piperazin-1-yl)-N-((4-phenyl-...) Show SMILES CCCc1nc(c(CNCCN2CCN(CC2)c2cccc(F)c2)o1)-c1ccccc1 Show InChI InChI=1S/C25H31FN4O/c1-2-7-24-28-25(20-8-4-3-5-9-20)23(31-24)19-27-12-13-29-14-16-30(17-15-29)22-11-6-10-21(26)18-22/h3-6,8-11,18,27H,2,7,12-17,19H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321393 (CHEMBL1172362 | N-((4-phenyl-2-propyloxazol-5-yl)m...) Show SMILES CCCc1nc(c(CNCCN2CCN(CC2)c2ccccc2C)o1)-c1ccccc1 Show InChI InChI=1S/C26H34N4O/c1-3-9-25-28-26(22-11-5-4-6-12-22)24(31-25)20-27-14-15-29-16-18-30(19-17-29)23-13-8-7-10-21(23)2/h4-8,10-13,27H,3,9,14-20H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321390 (2-(4-(2-chlorophenyl)piperazin-1-yl)-N-((4-phenyl-...) Show SMILES CCCc1nc(c(CNCCN2CCN(CC2)c2ccccc2Cl)o1)-c1ccccc1 Show InChI InChI=1S/C25H31ClN4O/c1-2-8-24-28-25(20-9-4-3-5-10-20)23(31-24)19-27-13-14-29-15-17-30(18-16-29)22-12-7-6-11-21(22)26/h3-7,9-12,27H,2,8,13-19H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321389 (2-(4-(4-fluorophenyl)piperazin-1-yl)-N-((4-phenyl-...) Show SMILES CCCc1nc(c(CNCCN2CCN(CC2)c2ccc(F)cc2)o1)-c1ccccc1 Show InChI InChI=1S/C25H31FN4O/c1-2-6-24-28-25(20-7-4-3-5-8-20)23(31-24)19-27-13-14-29-15-17-30(18-16-29)22-11-9-21(26)10-12-22/h3-5,7-12,27H,2,6,13-19H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321411 (CHEMBL1170781 | N-((4-phenyl-2-propyloxazol-5-yl)m...) Show SMILES CCCc1nc(c(CNCCCN2CCN(CC2)c2ccc(cc2)C(F)(F)F)o1)-c1ccccc1 Show InChI InChI=1S/C27H33F3N4O/c1-2-7-25-32-26(21-8-4-3-5-9-21)24(35-25)20-31-14-6-15-33-16-18-34(19-17-33)23-12-10-22(11-13-23)27(28,29)30/h3-5,8-13,31H,2,6-7,14-20H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321414 (2-(4-benzhydrylpiperazin-1-yl)-N-((4-phenyl-2-prop...) Show SMILES CCCc1nc(c(CNCCN2CCN(CC2)C(c2ccccc2)c2ccccc2)o1)-c1ccccc1 Show InChI InChI=1S/C32H38N4O/c1-2-12-30-34-31(26-13-6-3-7-14-26)29(37-30)25-33-19-20-35-21-23-36(24-22-35)32(27-15-8-4-9-16-27)28-17-10-5-11-18-28/h3-11,13-18,32-33H,2,12,19-25H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321407 (CHEMBL1170572 | N-((4-phenyl-2-propyloxazol-5-yl)m...) Show SMILES CCCc1nc(c(CNCCCN2CCN(CC2)c2ccccc2C)o1)-c1ccccc1 Show InChI InChI=1S/C27H36N4O/c1-3-10-26-29-27(23-12-5-4-6-13-23)25(32-26)21-28-15-9-16-30-17-19-31(20-18-30)24-14-8-7-11-22(24)2/h4-8,11-14,28H,3,9-10,15-21H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321394 (2-(4-(4-methoxyphenyl)piperazin-1-yl)-N-((4-phenyl...) Show SMILES CCCc1nc(c(CNCCN2CCN(CC2)c2ccc(OC)cc2)o1)-c1ccccc1 Show InChI InChI=1S/C26H34N4O2/c1-3-7-25-28-26(21-8-5-4-6-9-21)24(32-25)20-27-14-15-29-16-18-30(19-17-29)22-10-12-23(31-2)13-11-22/h4-6,8-13,27H,3,7,14-20H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321387 (CHEMBL1172331 | N-((4-phenyl-2-propyloxazol-5-yl)m...) Show SMILES CCCc1nc(c(CNCCN2CCN(CC2)c2ccccc2)o1)-c1ccccc1 Show InChI InChI=1S/C25H32N4O/c1-2-9-24-27-25(21-10-5-3-6-11-21)23(30-24)20-26-14-15-28-16-18-29(19-17-28)22-12-7-4-8-13-22/h3-8,10-13,26H,2,9,14-20H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321401 (3-(4-(2-fluorophenyl)piperazin-1-yl)-N-((4-phenyl-...) Show SMILES CCCc1nc(c(CNCCCN2CCN(CC2)c2ccccc2F)o1)-c1ccccc1 Show InChI InChI=1S/C26H33FN4O/c1-2-9-25-29-26(21-10-4-3-5-11-21)24(32-25)20-28-14-8-15-30-16-18-31(19-17-30)23-13-7-6-12-22(23)27/h3-7,10-13,28H,2,8-9,14-20H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.61E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50321409 (CHEMBL1171953 | N-((4-phenyl-2-propyloxazol-5-yl)m...) Show SMILES CCCc1nc(c(CNCCCN2CCN(CC2)c2ccc(C)cc2)o1)-c1ccccc1 Show InChI InChI=1S/C27H36N4O/c1-3-8-26-29-27(23-9-5-4-6-10-23)25(32-26)21-28-15-7-16-30-17-19-31(20-18-30)24-13-11-22(2)12-14-24/h4-6,9-14,28H,3,7-8,15-21H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay				Bioorg Med Chem Lett 20: 4219-22 (2010) Article DOI: 10.1016/j.bmcl.2010.05.030 BindingDB Entry DOI: 10.7270/Q2PN96KW
					More data for this Ligand-Target Pair