Compile Data Set for Download or QSAR

Found 61 hits Enz. Inhib. hit(s) with all data for entry = 50039556   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379979 (CHEMBL2012227) Show SMILES COc1ccc(-c2nc(C(=O)NCc3c(F)cccc3Cl)c(o2)[C@H](C)N)c2ccc(nc12)C(F)(F)F |r| Show InChI InChI=1S/C24H19ClF4N4O3/c1-11(30)21-20(22(34)31-10-14-15(25)4-3-5-16(14)26)33-23(36-21)13-6-8-17(35-2)19-12(13)7-9-18(32-19)24(27,28)29/h3-9,11H,10,30H2,1-2H3,(H,31,34)/t11-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379984 (CHEMBL2012232) Show SMILES COc1ccc(-c2nc(C(=O)NCc3c(F)cc(F)cc3F)c(o2)[C@H](C)N)c2ccc(nc12)C(F)(F)F |r| Show InChI InChI=1S/C24H18F6N4O3/c1-10(31)21-20(22(35)32-9-14-15(26)7-11(25)8-16(14)27)34-23(37-21)13-3-5-17(36-2)19-12(13)4-6-18(33-19)24(28,29)30/h3-8,10H,9,31H2,1-2H3,(H,32,35)/t10-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0400	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379961 (CHEMBL2012226) Show SMILES COc1ccc(-c2nc(C(=O)NCc3c(F)cccc3F)c(o2)[C@H](C)N)c2ccc(nc12)C(F)(F)F |r| Show InChI InChI=1S/C24H19F5N4O3/c1-11(30)21-20(22(34)31-10-14-15(25)4-3-5-16(14)26)33-23(36-21)13-6-8-17(35-2)19-12(13)7-9-18(32-19)24(27,28)29/h3-9,11H,10,30H2,1-2H3,(H,31,34)/t11-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0500	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379980 (CHEMBL2012228) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccc(F)cc3F)c(o2)[C@H](C)N)c2ccc(nc12)C(F)(F)F |r| Show InChI InChI=1S/C24H19F5N4O3/c1-11(30)21-20(22(34)31-10-12-3-4-13(25)9-16(12)26)33-23(36-21)15-5-7-17(35-2)19-14(15)6-8-18(32-19)24(27,28)29/h3-9,11H,10,30H2,1-2H3,(H,31,34)/t11-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0600	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379971 (CHEMBL2012218) Show SMILES COc1ccc(-c2nc(C(=O)NCc3c(F)cccc3Cl)c(CN)o2)c2ccc(nc12)C(F)(F)F Show InChI InChI=1S/C23H17ClF4N4O3/c1-34-16-7-5-12(11-6-8-18(23(26,27)28)31-19(11)16)22-32-20(17(9-29)35-22)21(33)30-10-13-14(24)3-2-4-15(13)25/h2-8H,9-10,29H2,1H3,(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379986 (CHEMBL2012237) Show SMILES COc1ccc(-c2nc(C(=O)N[C@H](CO)c3ccccc3)c(o2)[C@H](C)N)c2ccc(nc12)C(F)(F)F |r| Show InChI InChI=1S/C25H23F3N4O4/c1-13(29)22-21(23(34)30-17(12-33)14-6-4-3-5-7-14)32-24(36-22)16-8-10-18(35-2)20-15(16)9-11-19(31-20)25(26,27)28/h3-11,13,17,33H,12,29H2,1-2H3,(H,30,34)/t13-,17+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379977 (CHEMBL2012224) Show SMILES COc1ccc(-c2nc(C(=O)NCc3cccc(F)c3)c(o2)[C@H](C)N)c2ccc(nc12)C(F)(F)F |r| Show InChI InChI=1S/C24H20F4N4O3/c1-12(29)21-20(22(33)30-11-13-4-3-5-14(25)10-13)32-23(35-21)16-6-8-17(34-2)19-15(16)7-9-18(31-19)24(26,27)28/h3-10,12H,11,29H2,1-2H3,(H,30,33)/t12-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379978 (CHEMBL2012225) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccccc3F)c(o2)[C@H](C)N)c2ccc(nc12)C(F)(F)F |r| Show InChI InChI=1S/C24H20F4N4O3/c1-12(29)21-20(22(33)30-11-13-5-3-4-6-16(13)25)32-23(35-21)15-7-9-17(34-2)19-14(15)8-10-18(31-19)24(26,27)28/h3-10,12H,11,29H2,1-2H3,(H,30,33)/t12-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379976 (CHEMBL2012223) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccc(Cl)cc3)c(o2)[C@H](C)N)c2ccc(nc12)C(F)(F)F |r| Show InChI InChI=1S/C24H20ClF3N4O3/c1-12(29)21-20(22(33)30-11-13-3-5-14(25)6-4-13)32-23(35-21)16-7-9-17(34-2)19-15(16)8-10-18(31-19)24(26,27)28/h3-10,12H,11,29H2,1-2H3,(H,30,33)/t12-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.350	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379992 (CHEMBL2012235) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccc(F)cc3F)c(o2)[C@@H](N)C(C)C)c2ccc(nc12)C(F)(F)F |r| Show InChI InChI=1S/C26H23F5N4O3/c1-12(2)20(32)23-22(24(36)33-11-13-4-5-14(27)10-17(13)28)35-25(38-23)16-6-8-18(37-3)21-15(16)7-9-19(34-21)26(29,30)31/h4-10,12,20H,11,32H2,1-3H3,(H,33,36)/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.360	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379970 (CHEMBL2012217) Show SMILES COc1ccc(-c2nc(C(=O)NCc3c(F)cccc3F)c(CN)o2)c2ccc(nc12)C(F)(F)F Show InChI InChI=1S/C23H17F5N4O3/c1-34-16-7-5-12(11-6-8-18(23(26,27)28)31-19(11)16)22-32-20(17(9-29)35-22)21(33)30-10-13-14(24)3-2-4-15(13)25/h2-8H,9-10,29H2,1H3,(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379969 (CHEMBL2012216) Show SMILES COc1ccccc1CNC(=O)c1nc(oc1CN)-c1ccc(OC)c2nc(ccc12)C(F)(F)F Show InChI InChI=1S/C24H21F3N4O4/c1-33-16-6-4-3-5-13(16)12-29-22(32)21-18(11-28)35-23(31-21)15-7-9-17(34-2)20-14(15)8-10-19(30-20)24(25,26)27/h3-10H,11-12,28H2,1-2H3,(H,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379972 (CHEMBL2012219) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccc(F)cc3F)c(CN)o2)c2ccc(nc12)C(F)(F)F Show InChI InChI=1S/C23H17F5N4O3/c1-34-16-6-4-14(13-5-7-18(23(26,27)28)31-19(13)16)22-32-20(17(9-29)35-22)21(33)30-10-11-2-3-12(24)8-15(11)25/h2-8H,9-10,29H2,1H3,(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379983 (CHEMBL2012231) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccc(F)c(F)c3)c(o2)[C@H](C)N)c2ccc(nc12)C(F)(F)F |r| Show InChI InChI=1S/C24H19F5N4O3/c1-11(30)21-20(22(34)31-10-12-3-6-15(25)16(26)9-12)33-23(36-21)14-4-7-17(35-2)19-13(14)5-8-18(32-19)24(27,28)29/h3-9,11H,10,30H2,1-2H3,(H,31,34)/t11-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50379972 (CHEMBL2012219) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccc(F)cc3F)c(CN)o2)c2ccc(nc12)C(F)(F)F Show InChI InChI=1S/C23H17F5N4O3/c1-34-16-6-4-14(13-5-7-18(23(26,27)28)31-19(13)16)22-32-20(17(9-29)35-22)21(33)30-10-11-2-3-12(24)8-15(11)25/h2-8H,9-10,29H2,1H3,(H,30,33)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4D				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379982 (CHEMBL2012230) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccc(Cl)cc3Cl)c(o2)[C@H](C)N)c2ccc(nc12)C(F)(F)F |r| Show InChI InChI=1S/C24H19Cl2F3N4O3/c1-11(30)21-20(22(34)31-10-12-3-4-13(25)9-16(12)26)33-23(36-21)15-5-7-17(35-2)19-14(15)6-8-18(32-19)24(27,28)29/h3-9,11H,10,30H2,1-2H3,(H,31,34)/t11-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379981 (CHEMBL2012229) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccc(Cl)cc3F)c(o2)[C@H](C)N)c2ccc(nc12)C(F)(F)F |r| Show InChI InChI=1S/C24H19ClF4N4O3/c1-11(30)21-20(22(34)31-10-12-3-4-13(25)9-16(12)26)33-23(36-21)15-5-7-17(35-2)19-14(15)6-8-18(32-19)24(27,28)29/h3-9,11H,10,30H2,1-2H3,(H,31,34)/t11-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379990 (CHEMBL2012233) Show SMILES CC[C@H](N)c1oc(nc1C(=O)NCc1ccc(Cl)cc1)-c1ccc(OC)c2nc(ccc12)C(F)(F)F |r| Show InChI InChI=1S/C25H22ClF3N4O3/c1-3-17(30)22-21(23(34)31-12-13-4-6-14(26)7-5-13)33-24(36-22)16-8-10-18(35-2)20-15(16)9-11-19(32-20)25(27,28)29/h4-11,17H,3,12,30H2,1-2H3,(H,31,34)/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.810	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379967 (CHEMBL2012214) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccccc3F)c(CN)o2)c2ccc(nc12)C(F)(F)F Show InChI InChI=1S/C23H18F4N4O3/c1-33-16-8-6-14(13-7-9-18(23(25,26)27)30-19(13)16)22-31-20(17(10-28)34-22)21(32)29-11-12-4-2-3-5-15(12)24/h2-9H,10-11,28H2,1H3,(H,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379968 (CHEMBL2012215) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccccc3Cl)c(CN)o2)c2ccc(nc12)C(F)(F)F Show InChI InChI=1S/C23H18ClF3N4O3/c1-33-16-8-6-14(13-7-9-18(23(25,26)27)30-19(13)16)22-31-20(17(10-28)34-22)21(32)29-11-12-4-2-3-5-15(12)24/h2-9H,10-11,28H2,1H3,(H,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379966 (CHEMBL2012213) Show SMILES COc1ccc(-c2nc(C(=O)NCc3cccc(Cl)c3)c(CN)o2)c2ccc(nc12)C(F)(F)F Show InChI InChI=1S/C23H18ClF3N4O3/c1-33-16-7-5-15(14-6-8-18(23(25,26)27)30-19(14)16)22-31-20(17(10-28)34-22)21(32)29-11-12-3-2-4-13(24)9-12/h2-9H,10-11,28H2,1H3,(H,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379985 (CHEMBL2012236) Show SMILES COc1ccc(-c2nc(C(=O)N[C@H](CO)c3ccccc3)c(CN)o2)c2ccc(nc12)C(F)(F)F |r| Show InChI InChI=1S/C24H21F3N4O4/c1-34-17-9-7-15(14-8-10-19(24(25,26)27)30-20(14)17)23-31-21(18(11-28)35-23)22(33)29-16(12-32)13-5-3-2-4-6-13/h2-10,16,32H,11-12,28H2,1H3,(H,29,33)/t16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379965 (CHEMBL2012212) Show SMILES COc1ccc(-c2nc(C(=O)NCc3cccc(F)c3)c(CN)o2)c2ccc(nc12)C(F)(F)F Show InChI InChI=1S/C23H18F4N4O3/c1-33-16-7-5-15(14-6-8-18(23(25,26)27)30-19(14)16)22-31-20(17(10-28)34-22)21(32)29-11-12-3-2-4-13(24)9-12/h2-9H,10-11,28H2,1H3,(H,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379975 (CHEMBL2012222) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccc(F)c(F)c3)c(CN)o2)c2ccc(nc12)C(F)(F)F Show InChI InChI=1S/C23H17F5N4O3/c1-34-16-6-3-13(12-4-7-18(23(26,27)28)31-19(12)16)22-32-20(17(9-29)35-22)21(33)30-10-11-2-5-14(24)15(25)8-11/h2-8H,9-10,29H2,1H3,(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379973 (CHEMBL2012220) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccc(Cl)cc3F)c(CN)o2)c2ccc(nc12)C(F)(F)F Show InChI InChI=1S/C23H17ClF4N4O3/c1-34-16-6-4-14(13-5-7-18(23(26,27)28)31-19(13)16)22-32-20(17(9-29)35-22)21(33)30-10-11-2-3-12(24)8-15(11)25/h2-8H,9-10,29H2,1H3,(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379964 (CHEMBL2012209) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccc(Cl)cc3)c(CN)o2)c2ccc(nc12)C(F)(F)F Show InChI InChI=1S/C23H18ClF3N4O3/c1-33-16-8-6-15(14-7-9-18(23(25,26)27)30-19(14)16)22-31-20(17(10-28)34-22)21(32)29-11-12-2-4-13(24)5-3-12/h2-9H,10-11,28H2,1H3,(H,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379962 (CHEMBL2012207) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccccc3)c(CN)o2)c2ccc(nc12)C(F)(F)F Show InChI InChI=1S/C23H19F3N4O3/c1-32-16-9-7-15(14-8-10-18(23(24,25)26)29-19(14)16)22-30-20(17(11-27)33-22)21(31)28-12-13-5-3-2-4-6-13/h2-10H,11-12,27H2,1H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379963 (CHEMBL2012208) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccc(F)cc3)c(CN)o2)c2ccc(nc12)C(F)(F)F Show InChI InChI=1S/C23H18F4N4O3/c1-33-16-8-6-15(14-7-9-18(23(25,26)27)30-19(14)16)22-31-20(17(10-28)34-22)21(32)29-11-12-2-4-13(24)5-3-12/h2-9H,10-11,28H2,1H3,(H,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379974 (CHEMBL2012221) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccc(Cl)cc3Cl)c(CN)o2)c2ccc(nc12)C(F)(F)F Show InChI InChI=1S/C23H17Cl2F3N4O3/c1-34-16-6-4-14(13-5-7-18(23(26,27)28)31-19(13)16)22-32-20(17(9-29)35-22)21(33)30-10-11-2-3-12(24)8-15(11)25/h2-8H,9-10,29H2,1H3,(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379987 (CHEMBL2012238) Show SMILES COc1ccc(-c2nc(C(=O)N[C@H](CO)c3ccccc3)c(o2)[C@@H](C)N)c2ccc(nc12)C(F)(F)F |r| Show InChI InChI=1S/C25H23F3N4O4/c1-13(29)22-21(23(34)30-17(12-33)14-6-4-3-5-7-14)32-24(36-22)16-8-10-18(35-2)20-15(16)9-11-19(31-20)25(26,27)28/h3-11,13,17,33H,12,29H2,1-2H3,(H,30,34)/t13-,17-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379991 (CHEMBL2012234) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccc(Cl)cc3)c(o2)[C@@H](N)CO)c2ccc(nc12)C(F)(F)F |r| Show InChI InChI=1S/C24H20ClF3N4O4/c1-35-17-8-6-15(14-7-9-18(24(26,27)28)31-19(14)17)23-32-20(21(36-23)16(29)11-33)22(34)30-10-12-2-4-13(25)5-3-12/h2-9,16,33H,10-11,29H2,1H3,(H,30,34)/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12.7	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379988 (CHEMBL2012210) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccc(cc3)C#N)c(CN)o2)c2ccc(nc12)C(F)(F)F Show InChI InChI=1S/C24H18F3N5O3/c1-34-17-8-6-16(15-7-9-19(24(25,26)27)31-20(15)17)23-32-21(18(11-29)35-23)22(33)30-12-14-4-2-13(10-28)3-5-14/h2-9H,11-12,29H2,1H3,(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379989 (CHEMBL2012211) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccc(cc3)S(C)(=O)=O)c(CN)o2)c2ccc(nc12)C(F)(F)F Show InChI InChI=1S/C24H21F3N4O5S/c1-35-17-9-7-16(15-8-10-19(24(25,26)27)30-20(15)17)23-31-21(18(11-28)36-23)22(32)29-12-13-3-5-14(6-4-13)37(2,33)34/h3-10H,11-12,28H2,1-2H3,(H,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Homo sapiens (Human))	BDBM50379969 (CHEMBL2012216) Show SMILES COc1ccccc1CNC(=O)c1nc(oc1CN)-c1ccc(OC)c2nc(ccc12)C(F)(F)F Show InChI InChI=1S/C24H21F3N4O4/c1-33-16-6-4-3-5-13(16)12-29-22(32)21-18(11-28)35-23(31-21)15-7-9-17(34-2)20-14(15)8-10-19(30-20)24(25,26)27/h3-10H,11-12,28H2,1-2H3,(H,29,32)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE11				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Homo sapiens (Human))	BDBM50379974 (CHEMBL2012221) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccc(Cl)cc3Cl)c(CN)o2)c2ccc(nc12)C(F)(F)F Show InChI InChI=1S/C23H17Cl2F3N4O3/c1-34-16-6-4-14(13-5-7-18(23(26,27)28)31-19(13)16)22-32-20(17(9-29)35-22)21(33)30-10-11-2-3-12(24)8-15(11)25/h2-8H,9-10,29H2,1H3,(H,30,33)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE11				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Homo sapiens (Human))	BDBM50379976 (CHEMBL2012223) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccc(Cl)cc3)c(o2)[C@H](C)N)c2ccc(nc12)C(F)(F)F |r| Show InChI InChI=1S/C24H20ClF3N4O3/c1-12(29)21-20(22(33)30-11-13-3-5-14(25)6-4-13)32-23(35-21)16-7-9-17(34-2)19-15(16)8-10-18(31-19)24(26,27)28/h3-10,12H,11,29H2,1-2H3,(H,30,33)/t12-/m0/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE11				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Homo sapiens (Human))	BDBM50379978 (CHEMBL2012225) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccccc3F)c(o2)[C@H](C)N)c2ccc(nc12)C(F)(F)F |r| Show InChI InChI=1S/C24H20F4N4O3/c1-12(29)21-20(22(33)30-11-13-5-3-4-6-16(13)25)32-23(35-21)15-7-9-17(34-2)19-14(15)8-10-18(31-19)24(26,27)28/h3-10,12H,11,29H2,1-2H3,(H,30,33)/t12-/m0/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE11				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Homo sapiens (Human))	BDBM50379981 (CHEMBL2012229) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccc(Cl)cc3F)c(o2)[C@H](C)N)c2ccc(nc12)C(F)(F)F |r| Show InChI InChI=1S/C24H19ClF4N4O3/c1-11(30)21-20(22(34)31-10-12-3-4-13(25)9-16(12)26)33-23(36-21)15-5-7-17(35-2)19-14(15)6-8-18(32-19)24(27,28)29/h3-9,11H,10,30H2,1-2H3,(H,31,34)/t11-/m0/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE11				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Homo sapiens (Human))	BDBM50379971 (CHEMBL2012218) Show SMILES COc1ccc(-c2nc(C(=O)NCc3c(F)cccc3Cl)c(CN)o2)c2ccc(nc12)C(F)(F)F Show InChI InChI=1S/C23H17ClF4N4O3/c1-34-16-7-5-12(11-6-8-18(23(26,27)28)31-19(11)16)22-32-20(17(9-29)35-22)21(33)30-10-13-14(24)3-2-4-15(13)25/h2-8H,9-10,29H2,1H3,(H,30,33)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE11				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Homo sapiens (Human))	BDBM50379977 (CHEMBL2012224) Show SMILES COc1ccc(-c2nc(C(=O)NCc3cccc(F)c3)c(o2)[C@H](C)N)c2ccc(nc12)C(F)(F)F |r| Show InChI InChI=1S/C24H20F4N4O3/c1-12(29)21-20(22(33)30-11-13-4-3-5-14(25)10-13)32-23(35-21)16-6-8-17(34-2)19-15(16)7-9-18(31-19)24(26,27)28/h3-10,12H,11,29H2,1-2H3,(H,30,33)/t12-/m0/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE11				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Homo sapiens (Human))	BDBM50379961 (CHEMBL2012226) Show SMILES COc1ccc(-c2nc(C(=O)NCc3c(F)cccc3F)c(o2)[C@H](C)N)c2ccc(nc12)C(F)(F)F |r| Show InChI InChI=1S/C24H19F5N4O3/c1-11(30)21-20(22(34)31-10-14-15(25)4-3-5-16(14)26)33-23(36-21)13-6-8-17(35-2)19-12(13)7-9-18(32-19)24(27,28)29/h3-9,11H,10,30H2,1-2H3,(H,31,34)/t11-/m0/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE11				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Homo sapiens (Human))	BDBM50379979 (CHEMBL2012227) Show SMILES COc1ccc(-c2nc(C(=O)NCc3c(F)cccc3Cl)c(o2)[C@H](C)N)c2ccc(nc12)C(F)(F)F |r| Show InChI InChI=1S/C24H19ClF4N4O3/c1-11(30)21-20(22(34)31-10-14-15(25)4-3-5-16(14)26)33-23(36-21)13-6-8-17(35-2)19-12(13)7-9-18(32-19)24(27,28)29/h3-9,11H,10,30H2,1-2H3,(H,31,34)/t11-/m0/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE11				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Homo sapiens (Human))	BDBM50379982 (CHEMBL2012230) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccc(Cl)cc3Cl)c(o2)[C@H](C)N)c2ccc(nc12)C(F)(F)F |r| Show InChI InChI=1S/C24H19Cl2F3N4O3/c1-11(30)21-20(22(34)31-10-12-3-4-13(25)9-16(12)26)33-23(36-21)15-5-7-17(35-2)19-14(15)6-8-18(32-19)24(27,28)29/h3-9,11H,10,30H2,1-2H3,(H,31,34)/t11-/m0/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE11				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Homo sapiens (Human))	BDBM50379983 (CHEMBL2012231) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccc(F)c(F)c3)c(o2)[C@H](C)N)c2ccc(nc12)C(F)(F)F |r| Show InChI InChI=1S/C24H19F5N4O3/c1-11(30)21-20(22(34)31-10-12-3-6-15(25)16(26)9-12)33-23(36-21)14-4-7-17(35-2)19-13(14)5-8-18(32-19)24(27,28)29/h3-9,11H,10,30H2,1-2H3,(H,31,34)/t11-/m0/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE11				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Homo sapiens (Human))	BDBM50379966 (CHEMBL2012213) Show SMILES COc1ccc(-c2nc(C(=O)NCc3cccc(Cl)c3)c(CN)o2)c2ccc(nc12)C(F)(F)F Show InChI InChI=1S/C23H18ClF3N4O3/c1-33-16-7-5-15(14-6-8-18(23(25,26)27)30-19(14)16)22-31-20(17(10-28)34-22)21(32)29-11-12-3-2-4-13(24)9-12/h2-9H,10-11,28H2,1H3,(H,29,32)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE11				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Homo sapiens (Human))	BDBM50379975 (CHEMBL2012222) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccc(F)c(F)c3)c(CN)o2)c2ccc(nc12)C(F)(F)F Show InChI InChI=1S/C23H17F5N4O3/c1-34-16-6-3-13(12-4-7-18(23(26,27)28)31-19(12)16)22-32-20(17(9-29)35-22)21(33)30-10-11-2-5-14(24)15(25)8-11/h2-8H,9-10,29H2,1H3,(H,30,33)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE11				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Homo sapiens (Human))	BDBM50379972 (CHEMBL2012219) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccc(F)cc3F)c(CN)o2)c2ccc(nc12)C(F)(F)F Show InChI InChI=1S/C23H17F5N4O3/c1-34-16-6-4-14(13-5-7-18(23(26,27)28)31-19(13)16)22-32-20(17(9-29)35-22)21(33)30-10-11-2-3-12(24)8-15(11)25/h2-8H,9-10,29H2,1H3,(H,30,33)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE11				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Homo sapiens (Human))	BDBM50379968 (CHEMBL2012215) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccccc3Cl)c(CN)o2)c2ccc(nc12)C(F)(F)F Show InChI InChI=1S/C23H18ClF3N4O3/c1-33-16-8-6-14(13-7-9-18(23(25,26)27)30-19(13)16)22-31-20(17(10-28)34-22)21(32)29-11-12-4-2-3-5-15(12)24/h2-9H,10-11,28H2,1H3,(H,29,32)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE11				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Homo sapiens (Human))	BDBM50379980 (CHEMBL2012228) Show SMILES COc1ccc(-c2nc(C(=O)NCc3ccc(F)cc3F)c(o2)[C@H](C)N)c2ccc(nc12)C(F)(F)F |r| Show InChI InChI=1S/C24H19F5N4O3/c1-11(30)21-20(22(34)31-10-12-3-4-13(25)9-16(12)26)33-23(36-21)15-5-7-17(35-2)19-14(15)6-8-18(32-19)24(27,28)29/h3-9,11H,10,30H2,1-2H3,(H,31,34)/t11-/m0/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE11				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Homo sapiens (Human))	BDBM50379970 (CHEMBL2012217) Show SMILES COc1ccc(-c2nc(C(=O)NCc3c(F)cccc3F)c(CN)o2)c2ccc(nc12)C(F)(F)F Show InChI InChI=1S/C23H17F5N4O3/c1-34-16-7-5-12(11-6-8-18(23(26,27)28)31-19(11)16)22-32-20(17(9-29)35-22)21(33)30-10-13-14(24)3-2-4-15(13)25/h2-8H,9-10,29H2,1H3,(H,30,33)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE11				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair

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