Compile Data Set for Download or QSAR

Found 123 hits Enz. Inhib. hit(s) with all data for entry = 50036198   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50046841 (CHEMBL357864 | Morpholine-4-carboxylic acid {2-cyc...) Show SMILES CCC(C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)N1CCOCC1)C(=O)N[C@@H](Cc1ccc2ccccc2c1)[C@@H](O)[C@@H](O)CC(C)C Show InChI InChI=1S/C38H58N4O6/c1-5-26(4)34(41-36(45)32(23-27-11-7-6-8-12-27)40-38(47)42-17-19-48-20-18-42)37(46)39-31(35(44)33(43)21-25(2)3)24-28-15-16-29-13-9-10-14-30(29)22-28/h9-10,13-16,22,25-27,31-35,43-44H,5-8,11-12,17-21,23-24H2,1-4H3,(H,39,46)(H,40,47)(H,41,45)/t26?,31-,32-,33-,34-,35+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50368802 (CHEMBL1791097) Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)CCC(O)=O)C(=O)N[C@@H](Cc1ccc2ccccc2c1)[C@@H](O)[C@@H](O)CC(C)C Show InChI InChI=1S/C37H55N3O7/c1-5-24(4)34(40-36(46)30(21-25-11-7-6-8-12-25)38-32(42)17-18-33(43)44)37(47)39-29(35(45)31(41)19-23(2)3)22-26-15-16-27-13-9-10-14-28(27)20-26/h9-10,13-16,20,23-25,29-31,34-35,41,45H,5-8,11-12,17-19,21-22H2,1-4H3,(H,38,42)(H,39,47)(H,40,46)(H,43,44)/t24-,29+,30+,31+,34+,35-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50407080 (CHEMBL2112254) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc1ccc2ccccc2c1)[C@@H](O)[C@@H](O)CC(C)C Show InChI InChI=1S/C38H59N3O6/c1-8-25(4)33(41-35(44)31(22-26-14-10-9-11-15-26)40-37(46)47-38(5,6)7)36(45)39-30(34(43)32(42)20-24(2)3)23-27-18-19-28-16-12-13-17-29(28)21-27/h12-13,16-19,21,24-26,30-34,42-43H,8-11,14-15,20,22-23H2,1-7H3,(H,39,45)(H,40,46)(H,41,44)/t25-,30-,31-,32-,33-,34+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50407074 (CHEMBL2112267) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NS(=O)(=O)N1CCN(C)CC1)C(=O)N[C@@H](Cc1ccc2ccccc2c1)[C@@H](O)[C@@H](O)CC(C)C Show InChI InChI=1S/C38H61N5O6S/c1-6-27(4)35(40-37(46)33(24-28-12-8-7-9-13-28)41-50(48,49)43-20-18-42(5)19-21-43)38(47)39-32(36(45)34(44)22-26(2)3)25-29-16-17-30-14-10-11-15-31(30)23-29/h10-11,14-17,23,26-28,32-36,41,44-45H,6-9,12-13,18-22,24-25H2,1-5H3,(H,39,47)(H,40,46)/t27-,32-,33-,34-,35-,36+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50407089 (CHEMBL2112253) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(C)=O)C(=O)N[C@@H](Cc1ccc2ccccc2c1)[C@@H](O)[C@@H](O)CC(C)C Show InChI InChI=1S/C35H53N3O5/c1-6-23(4)32(38-34(42)30(36-24(5)39)20-25-12-8-7-9-13-25)35(43)37-29(33(41)31(40)18-22(2)3)21-26-16-17-27-14-10-11-15-28(27)19-26/h10-11,14-17,19,22-23,25,29-33,40-41H,6-9,12-13,18,20-21H2,1-5H3,(H,36,39)(H,37,43)(H,38,42)/t23-,29-,30-,31-,32-,33+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50407087 (CHEMBL2112258) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(C)C)[C@@H](O)CC(=O)NCCc1ccccn1 Show InChI InChI=1S/C35H59N5O6/c1-8-24(4)31(40-32(43)28(21-25-14-10-9-11-15-25)39-34(45)46-35(5,6)7)33(44)38-27(20-23(2)3)29(41)22-30(42)37-19-17-26-16-12-13-18-36-26/h12-13,16,18,23-25,27-29,31,41H,8-11,14-15,17,19-22H2,1-7H3,(H,37,42)(H,38,44)(H,39,45)(H,40,43)/t24-,27-,28-,29-,31-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50407076 (CHEMBL2112270) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(C)C)[C@@H](O)CC(=O)NCC(C)C Show InChI InChI=1S/C32H60N4O6/c1-10-22(6)28(30(40)34-24(16-20(2)3)26(37)18-27(38)33-19-21(4)5)36-29(39)25(17-23-14-12-11-13-15-23)35-31(41)42-32(7,8)9/h20-26,28,37H,10-19H2,1-9H3,(H,33,38)(H,34,40)(H,35,41)(H,36,39)/t22-,24-,25-,26-,28-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50407075 (CHEMBL2112262) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)[C@@H](O)[C@@H](O)CC(C)C Show InChI InChI=1S/C36H58N4O6/c1-8-23(4)31(40-33(43)29(19-24-14-10-9-11-15-24)39-35(45)46-36(5,6)7)34(44)38-28(32(42)30(41)18-22(2)3)20-25-21-37-27-17-13-12-16-26(25)27/h12-13,16-17,21-24,28-32,37,41-42H,8-11,14-15,18-20H2,1-7H3,(H,38,44)(H,39,45)(H,40,43)/t23-,28-,29-,30-,31-,32+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50407070 (CHEMBL2112268) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)N(C)CCN(C)C)C(=O)N[C@@H](Cc1ccc2ccccc2c1)[C@@H](O)[C@@H](O)CC(C)C Show InChI InChI=1S/C39H63N5O5/c1-8-27(4)35(42-37(47)33(24-28-14-10-9-11-15-28)41-39(49)44(7)21-20-43(5)6)38(48)40-32(36(46)34(45)22-26(2)3)25-29-18-19-30-16-12-13-17-31(30)23-29/h12-13,16-19,23,26-28,32-36,45-46H,8-11,14-15,20-22,24-25H2,1-7H3,(H,40,48)(H,41,49)(H,42,47)/t27-,32-,33-,34-,35-,36+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50046820 (4-Methyl-piperazine-1-carboxylic acid {2-cyclohexy...) Show SMILES CCC(C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)N1CCN(C)CC1)C(=O)N[C@@H](Cc1ccc2ccccc2c1)[C@@H](O)[C@@H](O)CC(C)C Show InChI InChI=1S/C39H61N5O5/c1-6-27(4)35(42-37(47)33(24-28-12-8-7-9-13-28)41-39(49)44-20-18-43(5)19-21-44)38(48)40-32(36(46)34(45)22-26(2)3)25-29-16-17-30-14-10-11-15-31(30)23-29/h10-11,14-17,23,26-28,32-36,45-46H,6-9,12-13,18-22,24-25H2,1-5H3,(H,40,48)(H,41,49)(H,42,47)/t27?,32-,33-,34-,35-,36+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50407071 (CHEMBL2112257) Show SMILES CC[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H](O)CC(C)C Show InChI InChI=1S/C31H59N3O6/c1-10-20(5)25(33-29(38)26(21(6)11-2)34-30(39)40-31(7,8)9)28(37)32-23(18-22-15-13-12-14-16-22)27(36)24(35)17-19(3)4/h19-27,35-36H,10-18H2,1-9H3,(H,32,37)(H,33,38)(H,34,39)/t20-,21-,23-,24-,25-,26-,27+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50368795 (CHEMBL1791129) Show SMILES CC[C@@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H]([C@H](C)CC)C(=O)N[C@@H](CC(C)C)C(O)CC(=O)N(C)CC(C)C Show InChI InChI=1S/C30H58N4O6/c1-13-20(7)25(32-28(38)26(21(8)14-2)33-29(39)40-30(9,10)11)27(37)31-22(15-18(3)4)23(35)16-24(36)34(12)17-19(5)6/h18-23,25-26,35H,13-17H2,1-12H3,(H,31,37)(H,32,38)(H,33,39)/t20-,21-,22+,23?,25+,26+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50368810 (CHEMBL1791125) Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(C)C)[C@@H](O)CC(=O)NCCN1CCOCC1 Show InChI InChI=1S/C34H63N5O7/c1-8-24(4)30(38-31(42)27(21-25-12-10-9-11-13-25)37-33(44)46-34(5,6)7)32(43)36-26(20-23(2)3)28(40)22-29(41)35-14-15-39-16-18-45-19-17-39/h23-28,30,40H,8-22H2,1-7H3,(H,35,41)(H,36,43)(H,37,44)(H,38,42)/t24-,26+,27+,28+,30+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50407072 (CHEMBL2112269) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(C)C)[C@@H](O)CC(=O)NCCN(C)C Show InChI InChI=1S/C32H61N5O6/c1-10-22(4)28(30(41)34-24(18-21(2)3)26(38)20-27(39)33-16-17-37(8)9)36-29(40)25(19-23-14-12-11-13-15-23)35-31(42)43-32(5,6)7/h21-26,28,38H,10-20H2,1-9H3,(H,33,39)(H,34,41)(H,35,42)(H,36,40)/t22-,24-,25-,26-,28-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50407088 (CHEMBL2112255) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H](O)CC(C)C Show InChI InChI=1S/C34H63N3O6/c1-8-23(4)29(32(41)35-26(20-24-15-11-9-12-16-24)30(39)28(38)19-22(2)3)37-31(40)27(21-25-17-13-10-14-18-25)36-33(42)43-34(5,6)7/h22-30,38-39H,8-21H2,1-7H3,(H,35,41)(H,36,42)(H,37,40)/t23-,26-,27-,28-,29-,30+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50368814 (CHEMBL1791126) Show SMILES CC[C@@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H]([C@H](C)CC)C(=O)N[C@@H](CC(C)C)C(O)CC(=O)NCCCCCCO Show InChI InChI=1S/C31H60N4O7/c1-10-21(5)26(34-29(40)27(22(6)11-2)35-30(41)42-31(7,8)9)28(39)33-23(18-20(3)4)24(37)19-25(38)32-16-14-12-13-15-17-36/h20-24,26-27,36-37H,10-19H2,1-9H3,(H,32,38)(H,33,39)(H,34,40)(H,35,41)/t21-,22-,23+,24?,26+,27+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50368798 (CHEMBL1791120) Show SMILES CC[C@@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H]([C@H](C)CC)C(=O)N[C@@H](CC(C)C)C(O)CC(=O)NCCC(C)C Show InChI InChI=1S/C30H58N4O6/c1-12-20(7)25(33-28(38)26(21(8)13-2)34-29(39)40-30(9,10)11)27(37)32-22(16-19(5)6)23(35)17-24(36)31-15-14-18(3)4/h18-23,25-26,35H,12-17H2,1-11H3,(H,31,36)(H,32,37)(H,33,38)(H,34,39)/t20-,21-,22+,23?,25+,26+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50407086 (CHEMBL2112265) Show SMILES CCOC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)OC(C)(C)C)[C@H](C)CC)[C@@H](C)CC Show InChI InChI=1S/C27H51N3O7/c1-11-17(6)22(24(33)28-19(14-16(4)5)20(31)15-21(32)36-13-3)29-25(34)23(18(7)12-2)30-26(35)37-27(8,9)10/h16-20,22-23,31H,11-15H2,1-10H3,(H,28,33)(H,29,34)(H,30,35)/t17-,18+,19-,20-,22-,23-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50046857 (CHEMBL143596 | [1-(1-{1-[1-Hydroxy-2-(4-hydroxy-bu...) Show SMILES CCC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](C(C)CC)C(=O)N[C@@H](CC(C)C)C(O)CC(=O)NCCCCO Show InChI InChI=1S/C29H56N4O7/c1-10-19(5)24(32-27(38)25(20(6)11-2)33-28(39)40-29(7,8)9)26(37)31-21(16-18(3)4)22(35)17-23(36)30-14-12-13-15-34/h18-22,24-25,34-35H,10-17H2,1-9H3,(H,30,36)(H,31,37)(H,32,38)(H,33,39)/t19?,20?,21-,22?,24-,25-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50407078 (CHEMBL2112272) Show SMILES CC[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(O)CC(=O)NCC(C)C Show InChI InChI=1S/C29H56N4O6/c1-12-19(7)24(32-27(37)25(20(8)13-2)33-28(38)39-29(9,10)11)26(36)31-21(14-17(3)4)22(34)15-23(35)30-16-18(5)6/h17-22,24-25,34H,12-16H2,1-11H3,(H,30,35)(H,31,36)(H,32,37)(H,33,38)/t19-,20-,21-,22?,24-,25-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50046842 (3-{4-[2-(2-tert-Butoxycarbonylamino-3-methyl-penta...) Show SMILES CCOC(=O)CCNC(=O)CC(O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)CC)C(C)CC Show InChI InChI=1S/C30H56N4O8/c1-11-19(6)25(33-28(39)26(20(7)12-2)34-29(40)42-30(8,9)10)27(38)32-21(16-18(4)5)22(35)17-23(36)31-15-14-24(37)41-13-3/h18-22,25-26,35H,11-17H2,1-10H3,(H,31,36)(H,32,38)(H,33,39)(H,34,40)/t19?,20?,21-,22?,25-,26-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50368806 (CHEMBL1791099) Show SMILES CC[C@@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H]([C@H](C)CC)C(=O)N[C@@H](CC(C)C)C(O)CC(=O)NC[C@@H](C)O Show InChI InChI=1S/C28H54N4O7/c1-11-17(5)23(31-26(37)24(18(6)12-2)32-27(38)39-28(8,9)10)25(36)30-20(13-16(3)4)21(34)14-22(35)29-15-19(7)33/h16-21,23-24,33-34H,11-15H2,1-10H3,(H,29,35)(H,30,36)(H,31,37)(H,32,38)/t17-,18-,19-,20+,21?,23+,24+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50368788 (CHEMBL1791112) Show SMILES CCOC(=O)CC(O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C)[C@H](C)CC Show InChI InChI=1S/C30H55N3O7/c1-9-20(5)26(28(37)31-22(16-19(3)4)24(34)18-25(35)39-10-2)33-27(36)23(17-21-14-12-11-13-15-21)32-29(38)40-30(6,7)8/h19-24,26,34H,9-18H2,1-8H3,(H,31,37)(H,32,38)(H,33,36)/t20-,22+,23+,24?,26+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50407090 (CHEMBL2112837) Show SMILES CCOC(=O)CC(O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)(C)C)NC(=O)OC(C)(C)C)[C@@H](C)CC |r| Show InChI InChI=1S/C28H53N3O7/c1-12-18(5)23(25(35)29-19(14-17(3)4)21(32)15-22(33)37-13-2)31-24(34)20(16-27(6,7)8)30-26(36)38-28(9,10)11/h17-21,23,32H,12-16H2,1-11H3,(H,29,35)(H,30,36)(H,31,34)/t18-,19-,20-,21?,23-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Cathepsin D (Bos taurus)	BDBM50407076 (CHEMBL2112270) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(C)C)[C@@H](O)CC(=O)NCC(C)C Show InChI InChI=1S/C32H60N4O6/c1-10-22(6)28(30(40)34-24(16-20(2)3)26(37)18-27(38)33-19-21(4)5)36-29(39)25(17-23-14-12-11-13-15-23)35-31(41)42-32(7,8)9/h20-26,28,37H,10-19H2,1-9H3,(H,33,38)(H,34,40)(H,35,41)(H,36,39)/t22-,24-,25-,26-,28-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of hemoglobin by commercially purchased bovine spleen cathepsin D.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50407083 (CHEMBL2112251) Show SMILES CC[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(O)CC(=O)N[C@@H](C(C)C)C(=O)NC(CC(N)=O)C(=O)NC[C@@H](C)O Show InChI InChI=1S/C37H69N7O10/c1-13-21(7)30(43-35(52)31(22(8)14-2)44-36(53)54-37(10,11)12)34(51)40-24(15-19(3)4)26(46)17-28(48)42-29(20(5)6)33(50)41-25(16-27(38)47)32(49)39-18-23(9)45/h19-26,29-31,45-46H,13-18H2,1-12H3,(H2,38,47)(H,39,49)(H,40,51)(H,41,50)(H,42,48)(H,43,52)(H,44,53)/t21-,22-,23+,24-,25?,26?,29-,30-,31-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50046856 (CHEMBL143902 | [1-(1-{1-[1-Hydroxy-2-(5-hydroxy-pe...) Show SMILES CCC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](C(C)CC)C(=O)N[C@@H](CC(C)C)C(O)CC(=O)NCCCCCO Show InChI InChI=1S/C30H58N4O7/c1-10-20(5)25(33-28(39)26(21(6)11-2)34-29(40)41-30(7,8)9)27(38)32-22(17-19(3)4)23(36)18-24(37)31-15-13-12-14-16-35/h19-23,25-26,35-36H,10-18H2,1-9H3,(H,31,37)(H,32,38)(H,33,39)(H,34,40)/t20?,21?,22-,23?,25-,26-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Cathepsin D (Bos taurus)	BDBM50407086 (CHEMBL2112265) Show SMILES CCOC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)OC(C)(C)C)[C@H](C)CC)[C@@H](C)CC Show InChI InChI=1S/C27H51N3O7/c1-11-17(6)22(24(33)28-19(14-16(4)5)20(31)15-21(32)36-13-3)29-25(34)23(18(7)12-2)30-26(35)37-27(8,9)10/h16-20,22-23,31H,11-15H2,1-10H3,(H,28,33)(H,29,34)(H,30,35)/t17-,18+,19-,20-,22-,23-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of hemoglobin by commercially purchased bovine spleen cathepsin D.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50368799 (CHEMBL1791102) Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc1cccc2ccccc12)[C@@H](O)[C@@H](O)CC(C)C Show InChI InChI=1S/C38H59N3O6/c1-8-25(4)33(41-35(44)31(22-26-15-10-9-11-16-26)40-37(46)47-38(5,6)7)36(45)39-30(34(43)32(42)21-24(2)3)23-28-19-14-18-27-17-12-13-20-29(27)28/h12-14,17-20,24-26,30-34,42-43H,8-11,15-16,21-23H2,1-7H3,(H,39,45)(H,40,46)(H,41,44)/t25-,30+,31+,32+,33+,34-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50407085 (CHEMBL2112259) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)CC(=O)N[C@@H](C(C)C)C(O)=O Show InChI InChI=1S/C38H59N5O8/c1-8-23(4)33(43-34(46)29(18-24-14-10-9-11-15-24)41-37(50)51-38(5,6)7)35(47)40-28(19-25-21-39-27-17-13-12-16-26(25)27)30(44)20-31(45)42-32(22(2)3)36(48)49/h12-13,16-17,21-24,28-30,32-33,39,44H,8-11,14-15,18-20H2,1-7H3,(H,40,47)(H,41,50)(H,42,45)(H,43,46)(H,48,49)/t23-,28-,29-,30?,32-,33-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50407079 (CHEMBL2112261) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(C)C)C(O)CC(O)=O Show InChI InChI=1S/C28H51N3O7/c1-8-18(4)24(26(36)29-20(14-17(2)3)22(32)16-23(33)34)31-25(35)21(15-19-12-10-9-11-13-19)30-27(37)38-28(5,6)7/h17-22,24,32H,8-16H2,1-7H3,(H,29,36)(H,30,37)(H,31,35)(H,33,34)/t18-,20-,21-,22?,24-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50368786 (CHEMBL1791119) Show SMILES CC[C@@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H]([C@H](C)CC)C(=O)N[C@@H](CC(C)C)C(O)CC(=O)NC(C)C Show InChI InChI=1S/C28H54N4O6/c1-12-18(7)23(31-26(36)24(19(8)13-2)32-27(37)38-28(9,10)11)25(35)30-20(14-16(3)4)21(33)15-22(34)29-17(5)6/h16-21,23-24,33H,12-15H2,1-11H3,(H,29,34)(H,30,35)(H,31,36)(H,32,37)/t18-,19-,20+,21?,23+,24+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Renin (Homo sapiens (Human))	BDBM50407071 (CHEMBL2112257) Show SMILES CC[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H](O)CC(C)C Show InChI InChI=1S/C31H59N3O6/c1-10-20(5)25(33-29(38)26(21(6)11-2)34-30(39)40-31(7,8)9)28(37)32-23(18-22-15-13-12-14-16-22)27(36)24(35)17-19(3)4/h19-27,35-36H,10-18H2,1-9H3,(H,32,37)(H,33,38)(H,34,39)/t20-,21-,23-,24-,25-,26-,27+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	6.0	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of partially purified human renin at pH 6.0.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Cathepsin D (Bos taurus)	BDBM50407087 (CHEMBL2112258) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(C)C)[C@@H](O)CC(=O)NCCc1ccccn1 Show InChI InChI=1S/C35H59N5O6/c1-8-24(4)31(40-32(43)28(21-25-14-10-9-11-15-25)39-34(45)46-35(5,6)7)33(44)38-27(20-23(2)3)29(41)22-30(42)37-19-17-26-16-12-13-18-36-26/h12-13,16,18,23-25,27-29,31,41H,8-11,14-15,17,19-22H2,1-7H3,(H,37,42)(H,38,44)(H,39,45)(H,40,43)/t24-,27-,28-,29-,31-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of hemoglobin by commercially purchased bovine spleen cathepsin D.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50407081 (CHEMBL2112256) Show SMILES CCOC(=O)CC(O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)OC(C)(C)C)C1CCCCC1)[C@@H](C)CC Show InChI InChI=1S/C29H53N3O7/c1-9-19(5)24(26(35)30-21(16-18(3)4)22(33)17-23(34)38-10-2)31-27(36)25(20-14-12-11-13-15-20)32-28(37)39-29(6,7)8/h18-22,24-25,33H,9-17H2,1-8H3,(H,30,35)(H,31,36)(H,32,37)/t19-,21-,22?,24-,25-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Cathepsin D (Bos taurus)	BDBM50046856 (CHEMBL143902 | [1-(1-{1-[1-Hydroxy-2-(5-hydroxy-pe...) Show SMILES CCC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](C(C)CC)C(=O)N[C@@H](CC(C)C)C(O)CC(=O)NCCCCCO Show InChI InChI=1S/C30H58N4O7/c1-10-20(5)25(33-28(39)26(21(6)11-2)34-29(40)41-30(7,8)9)27(38)32-22(17-19(3)4)23(36)18-24(37)31-15-13-12-14-16-35/h19-23,25-26,35-36H,10-18H2,1-9H3,(H,31,37)(H,32,38)(H,33,39)(H,34,40)/t20?,21?,22-,23?,25-,26-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of hemoglobin by commercially purchased bovine spleen cathepsin D.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Cathepsin D (Bos taurus)	BDBM50407088 (CHEMBL2112255) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H](O)CC(C)C Show InChI InChI=1S/C34H63N3O6/c1-8-23(4)29(32(41)35-26(20-24-15-11-9-12-16-24)30(39)28(38)19-22(2)3)37-31(40)27(21-25-17-13-10-14-18-25)36-33(42)43-34(5,6)7/h22-30,38-39H,8-21H2,1-7H3,(H,35,41)(H,36,42)(H,37,40)/t23-,26-,27-,28-,29-,30+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of hemoglobin by commercially purchased bovine spleen cathepsin D.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50046833 (3-{4-[2-(2-tert-Butoxycarbonylamino-3-methyl-penta...) Show SMILES CCC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](C(C)CC)C(=O)N[C@@H](CC(C)C)C(O)CC(=O)NCCC(O)=O Show InChI InChI=1S/C28H52N4O8/c1-10-17(5)23(31-26(38)24(18(6)11-2)32-27(39)40-28(7,8)9)25(37)30-19(14-16(3)4)20(33)15-21(34)29-13-12-22(35)36/h16-20,23-24,33H,10-15H2,1-9H3,(H,29,34)(H,30,37)(H,31,38)(H,32,39)(H,35,36)/t17?,18?,19-,20?,23-,24-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Cathepsin D (Bos taurus)	BDBM50368795 (CHEMBL1791129) Show SMILES CC[C@@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H]([C@H](C)CC)C(=O)N[C@@H](CC(C)C)C(O)CC(=O)N(C)CC(C)C Show InChI InChI=1S/C30H58N4O6/c1-13-20(7)25(32-28(38)26(21(8)14-2)33-29(39)40-30(9,10)11)27(37)31-22(15-18(3)4)23(35)16-24(36)34(12)17-19(5)6/h18-23,25-26,35H,13-17H2,1-12H3,(H,31,37)(H,32,38)(H,33,39)/t20-,21-,22+,23?,25+,26+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of hemoglobin by commercially purchased bovine spleen cathepsin D.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50407082 (CHEMBL2112836) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)(C)C)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(C)C)C(O)CC(O)=O |r| Show InChI InChI=1S/C26H49N3O7/c1-11-16(4)21(23(34)27-17(12-15(2)3)19(30)13-20(31)32)29-22(33)18(14-25(5,6)7)28-24(35)36-26(8,9)10/h15-19,21,30H,11-14H2,1-10H3,(H,27,34)(H,28,35)(H,29,33)(H,31,32)/t16-,17-,18-,19?,21-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Cathepsin D (Bos taurus)	BDBM50368788 (CHEMBL1791112) Show SMILES CCOC(=O)CC(O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C)[C@H](C)CC Show InChI InChI=1S/C30H55N3O7/c1-9-20(5)26(28(37)31-22(16-19(3)4)24(34)18-25(35)39-10-2)33-27(36)23(17-21-14-12-11-13-15-21)32-29(38)40-30(6,7)8/h19-24,26,34H,9-18H2,1-8H3,(H,31,37)(H,32,38)(H,33,36)/t20-,22+,23+,24?,26+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of hemoglobin by commercially purchased bovine spleen cathepsin D.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Cathepsin D (Bos taurus)	BDBM50046842 (3-{4-[2-(2-tert-Butoxycarbonylamino-3-methyl-penta...) Show SMILES CCOC(=O)CCNC(=O)CC(O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)CC)C(C)CC Show InChI InChI=1S/C30H56N4O8/c1-11-19(6)25(33-28(39)26(20(7)12-2)34-29(40)42-30(8,9)10)27(38)32-21(16-18(4)5)22(35)17-23(36)31-15-14-24(37)41-13-3/h18-22,25-26,35H,11-17H2,1-10H3,(H,31,36)(H,32,38)(H,33,39)(H,34,40)/t19?,20?,21-,22?,25-,26-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of hemoglobin by commercially purchased bovine spleen cathepsin D.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Cathepsin D (Bos taurus)	BDBM50368802 (CHEMBL1791097) Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)CCC(O)=O)C(=O)N[C@@H](Cc1ccc2ccccc2c1)[C@@H](O)[C@@H](O)CC(C)C Show InChI InChI=1S/C37H55N3O7/c1-5-24(4)34(40-36(46)30(21-25-11-7-6-8-12-25)38-32(42)17-18-33(43)44)37(47)39-29(35(45)31(41)19-23(2)3)22-26-15-16-27-13-9-10-14-28(27)20-26/h9-10,13-16,20,23-25,29-31,34-35,41,45H,5-8,11-12,17-19,21-22H2,1-4H3,(H,38,42)(H,39,47)(H,40,46)(H,43,44)/t24-,29+,30+,31+,34+,35-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of hemoglobin by commercially purchased bovine spleen cathepsin D.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Cathepsin D (Bos taurus)	BDBM50407071 (CHEMBL2112257) Show SMILES CC[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H](O)CC(C)C Show InChI InChI=1S/C31H59N3O6/c1-10-20(5)25(33-29(38)26(21(6)11-2)34-30(39)40-31(7,8)9)28(37)32-23(18-22-15-13-12-14-16-22)27(36)24(35)17-19(3)4/h19-27,35-36H,10-18H2,1-9H3,(H,32,37)(H,33,38)(H,34,39)/t20-,21-,23-,24-,25-,26-,27+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of hemoglobin by commercially purchased bovine spleen cathepsin D.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Cathepsin D (Bos taurus)	BDBM50407080 (CHEMBL2112254) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc1ccc2ccccc2c1)[C@@H](O)[C@@H](O)CC(C)C Show InChI InChI=1S/C38H59N3O6/c1-8-25(4)33(41-35(44)31(22-26-14-10-9-11-15-26)40-37(46)47-38(5,6)7)36(45)39-30(34(43)32(42)20-24(2)3)23-27-18-19-28-16-12-13-17-29(28)21-27/h12-13,16-19,21,24-26,30-34,42-43H,8-11,14-15,20,22-23H2,1-7H3,(H,39,45)(H,40,46)(H,41,44)/t25-,30-,31-,32-,33-,34+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of hemoglobin by commercially purchased bovine spleen cathepsin D.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Cathepsin D (Bos taurus)	BDBM50407078 (CHEMBL2112272) Show SMILES CC[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(O)CC(=O)NCC(C)C Show InChI InChI=1S/C29H56N4O6/c1-12-19(7)24(32-27(37)25(20(8)13-2)33-28(38)39-29(9,10)11)26(36)31-21(14-17(3)4)22(34)15-23(35)30-16-18(5)6/h17-22,24-25,34H,12-16H2,1-11H3,(H,30,35)(H,31,36)(H,32,37)(H,33,38)/t19-,20-,21-,22?,24-,25-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of hemoglobin by commercially purchased bovine spleen cathepsin D.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50407077 (CHEMBL2112264) Show SMILES CCOC(=O)C[C@@H](O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)OC(C)(C)C)[C@@H](C)CC)[C@@H](C)CC Show InChI InChI=1S/C27H51N3O7/c1-11-17(6)22(24(33)28-19(14-16(4)5)20(31)15-21(32)36-13-3)29-25(34)23(18(7)12-2)30-26(35)37-27(8,9)10/h16-20,22-23,31H,11-15H2,1-10H3,(H,28,33)(H,29,34)(H,30,35)/t17-,18-,19-,20+,22-,23-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Rattus norvegicus (Rat))	BDBM50046861 (2-(2-Amino-3-cyclohexyl-propionylamino)-3-methyl-p...) Show SMILES CCC(C)[C@H](NC(=O)[C@@H](N)CC1CCCCC1)C(=O)N[C@@H](Cc1ccc2ccccc2c1)[C@@H](O)[C@@H](O)CC(C)C Show InChI InChI=1S/C33H51N3O4/c1-5-22(4)30(36-32(39)27(34)19-23-11-7-6-8-12-23)33(40)35-28(31(38)29(37)17-21(2)3)20-24-15-16-25-13-9-10-14-26(25)18-24/h9-10,13-16,18,21-23,27-31,37-38H,5-8,11-12,17,19-20,34H2,1-4H3,(H,35,40)(H,36,39)/t22?,27-,28-,29-,30-,31+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Cathepsin D (Bos taurus)	BDBM50046841 (CHEMBL357864 | Morpholine-4-carboxylic acid {2-cyc...) Show SMILES CCC(C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)N1CCOCC1)C(=O)N[C@@H](Cc1ccc2ccccc2c1)[C@@H](O)[C@@H](O)CC(C)C Show InChI InChI=1S/C38H58N4O6/c1-5-26(4)34(41-36(45)32(23-27-11-7-6-8-12-27)40-38(47)42-17-19-48-20-18-42)37(46)39-31(35(44)33(43)21-25(2)3)24-28-15-16-29-13-9-10-14-30(29)22-28/h9-10,13-16,22,25-27,31-35,43-44H,5-8,11-12,17-21,23-24H2,1-4H3,(H,39,46)(H,40,47)(H,41,45)/t26?,31-,32-,33-,34-,35+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of conversion of hemoglobin by commercially purchased bovine spleen cathepsin D.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair
Cathepsin D (Bos taurus)	BDBM50368814 (CHEMBL1791126) Show SMILES CC[C@@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H]([C@H](C)CC)C(=O)N[C@@H](CC(C)C)C(O)CC(=O)NCCCCCCO Show InChI InChI=1S/C31H60N4O7/c1-10-21(5)26(34-29(40)27(22(6)11-2)35-30(41)42-31(7,8)9)28(39)33-23(18-20(3)4)24(37)19-25(38)32-16-14-12-13-15-17-36/h20-24,26-27,36-37H,10-19H2,1-9H3,(H,32,38)(H,33,39)(H,34,40)(H,35,41)/t21-,22-,23+,24?,26+,27+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of onversion of hemoglobin by commercially purchased bovine spleen Cathepsin D.				J Med Chem 36: 468-78 (1993) BindingDB Entry DOI: 10.7270/Q2PC331F
					More data for this Ligand-Target Pair

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