Found 22 hits Enz. Inhib. hit(s) with all data for entry = 50001653 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human)) | BDBM50291408
(CHEMBL4165600)Show SMILES COc1ccc(N\N=C\c2c(C)nn(c2Oc2ccc(cc2)-c2nc3cc(ccc3[nH]2)C(O)=O)-c2ccccc2)cc1 Show InChI InChI=1S/C32H26N6O4/c1-20-27(19-33-36-23-11-15-25(41-2)16-12-23)31(38(37-20)24-6-4-3-5-7-24)42-26-13-8-21(9-14-26)30-34-28-17-10-22(32(39)40)18-29(28)35-30/h3-19,36H,1-2H3,(H,34,35)(H,39,40)/b33-19+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Centre
Curated by ChEMBL
| Assay Description
Inhibition of Chk2 (unknown origin) by spectrophotometric analysis |
Eur J Med Chem 144: 859-873 (2018)
Article DOI: 10.1016/j.ejmech.2017.12.023
BindingDB Entry DOI: 10.7270/Q2KD21F1 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human)) | BDBM50291372
(CHEMBL4177291)Show SMILES Cc1nn(c(Oc2ccc(cc2)-c2nc3cc(ccc3[nH]2)[N+]([O-])=O)c1\C=N\NC(N)=S)-c1ccccc1 Show InChI InChI=1S/C25H20N8O3S/c1-15-20(14-27-30-25(26)37)24(32(31-15)17-5-3-2-4-6-17)36-19-10-7-16(8-11-19)23-28-21-12-9-18(33(34)35)13-22(21)29-23/h2-14H,1H3,(H,28,29)(H3,26,30,37)/b27-14+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Centre
Curated by ChEMBL
| Assay Description
Inhibition of Chk2 (unknown origin) by spectrophotometric analysis |
Eur J Med Chem 144: 859-873 (2018)
Article DOI: 10.1016/j.ejmech.2017.12.023
BindingDB Entry DOI: 10.7270/Q2KD21F1 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human)) | BDBM50291380
(CHEMBL4170221)Show SMILES Cc1nn(c(Oc2ccc(cc2)-c2nc3cc(ccc3[nH]2)C(N)=O)c1\C=N\NC(N)=O)-c1ccccc1 Show InChI InChI=1S/C26H22N8O3/c1-15-20(14-29-32-26(28)36)25(34(33-15)18-5-3-2-4-6-18)37-19-10-7-16(8-11-19)24-30-21-12-9-17(23(27)35)13-22(21)31-24/h2-14H,1H3,(H2,27,35)(H,30,31)(H3,28,32,36)/b29-14+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Centre
Curated by ChEMBL
| Assay Description
Inhibition of Chk2 (unknown origin) by spectrophotometric analysis |
Eur J Med Chem 144: 859-873 (2018)
Article DOI: 10.1016/j.ejmech.2017.12.023
BindingDB Entry DOI: 10.7270/Q2KD21F1 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human)) | BDBM50291376
(CHEMBL4170505)Show SMILES Cc1nn(c(Oc2ccc(cc2)-c2nc3cc(ccc3[nH]2)[N+]([O-])=O)c1\C=N\Nc1ccccc1)-c1ccccc1 Show InChI InChI=1S/C30H23N7O3/c1-20-26(19-31-34-22-8-4-2-5-9-22)30(36(35-20)23-10-6-3-7-11-23)40-25-15-12-21(13-16-25)29-32-27-17-14-24(37(38)39)18-28(27)33-29/h2-19,34H,1H3,(H,32,33)/b31-19+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Centre
Curated by ChEMBL
| Assay Description
Inhibition of Chk2 (unknown origin) by spectrophotometric analysis |
Eur J Med Chem 144: 859-873 (2018)
Article DOI: 10.1016/j.ejmech.2017.12.023
BindingDB Entry DOI: 10.7270/Q2KD21F1 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human)) | BDBM50291405
(CHEMBL4173655)Show SMILES Cc1nn(c(Oc2ccc(cc2)-c2nc3cc(ccc3[nH]2)C(O)=O)c1\C=N\NC(N)=S)-c1ccccc1 Show InChI InChI=1S/C26H21N7O3S/c1-15-20(14-28-31-26(27)37)24(33(32-15)18-5-3-2-4-6-18)36-19-10-7-16(8-11-19)23-29-21-12-9-17(25(34)35)13-22(21)30-23/h2-14H,1H3,(H,29,30)(H,34,35)(H3,27,31,37)/b28-14+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Centre
Curated by ChEMBL
| Assay Description
Inhibition of Chk2 (unknown origin) by spectrophotometric analysis |
Eur J Med Chem 144: 859-873 (2018)
Article DOI: 10.1016/j.ejmech.2017.12.023
BindingDB Entry DOI: 10.7270/Q2KD21F1 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human)) | BDBM50291406
(CHEMBL4165737)Show SMILES Cc1nn(c(Oc2ccc(cc2)-c2nc3cc(ccc3[nH]2)C(O)=O)c1\C=N\NC(N)=O)-c1ccccc1 Show InChI InChI=1S/C26H21N7O4/c1-15-20(14-28-31-26(27)36)24(33(32-15)18-5-3-2-4-6-18)37-19-10-7-16(8-11-19)23-29-21-12-9-17(25(34)35)13-22(21)30-23/h2-14H,1H3,(H,29,30)(H,34,35)(H3,27,31,36)/b28-14+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Centre
Curated by ChEMBL
| Assay Description
Inhibition of Chk2 (unknown origin) by spectrophotometric analysis |
Eur J Med Chem 144: 859-873 (2018)
Article DOI: 10.1016/j.ejmech.2017.12.023
BindingDB Entry DOI: 10.7270/Q2KD21F1 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human)) | BDBM50291383
(CHEMBL4177437)Show SMILES Cc1nn(c(Oc2ccc(cc2)-c2nc3cc(ccc3[nH]2)C(N)=O)c1\C=N\Nc1ccccc1)-c1ccccc1 Show InChI InChI=1S/C31H25N7O2/c1-20-26(19-33-36-23-8-4-2-5-9-23)31(38(37-20)24-10-6-3-7-11-24)40-25-15-12-21(13-16-25)30-34-27-17-14-22(29(32)39)18-28(27)35-30/h2-19,36H,1H3,(H2,32,39)(H,34,35)/b33-19+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Centre
Curated by ChEMBL
| Assay Description
Inhibition of Chk2 (unknown origin) by spectrophotometric analysis |
Eur J Med Chem 144: 859-873 (2018)
Article DOI: 10.1016/j.ejmech.2017.12.023
BindingDB Entry DOI: 10.7270/Q2KD21F1 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human)) | BDBM50291384
(CHEMBL4177025)Show SMILES Cc1nn(c(Sc2ccc(cc2)-c2nc3cc(ccc3[nH]2)C(O)=O)c1\C=N\NC(N)=O)-c1ccccc1 Show InChI InChI=1S/C26H21N7O3S/c1-15-20(14-28-31-26(27)36)24(33(32-15)18-5-3-2-4-6-18)37-19-10-7-16(8-11-19)23-29-21-12-9-17(25(34)35)13-22(21)30-23/h2-14H,1H3,(H,29,30)(H,34,35)(H3,27,31,36)/b28-14+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Centre
Curated by ChEMBL
| Assay Description
Inhibition of Chk2 (unknown origin) by spectrophotometric analysis |
Eur J Med Chem 144: 859-873 (2018)
Article DOI: 10.1016/j.ejmech.2017.12.023
BindingDB Entry DOI: 10.7270/Q2KD21F1 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human)) | BDBM50291381
(CHEMBL4162300)Show SMILES Cc1nn(c(Oc2ccc(cc2)-c2nc3cc(ccc3[nH]2)C(N)=O)c1\C=N\Nc1ccc(cc1)[N+]([O-])=O)-c1ccccc1 Show InChI InChI=1S/C31H24N8O4/c1-19-26(18-33-36-22-10-12-24(13-11-22)39(41)42)31(38(37-19)23-5-3-2-4-6-23)43-25-14-7-20(8-15-25)30-34-27-16-9-21(29(32)40)17-28(27)35-30/h2-18,36H,1H3,(H2,32,40)(H,34,35)/b33-18+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Centre
Curated by ChEMBL
| Assay Description
Inhibition of Chk2 (unknown origin) by spectrophotometric analysis |
Eur J Med Chem 144: 859-873 (2018)
Article DOI: 10.1016/j.ejmech.2017.12.023
BindingDB Entry DOI: 10.7270/Q2KD21F1 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human)) | BDBM50291379
(CHEMBL4160826)Show SMILES Cc1nn(c(Oc2ccc(cc2)-c2nc3cc(ccc3[nH]2)C(N)=O)c1\C=N\NC(N)=S)-c1ccccc1 Show InChI InChI=1S/C26H22N8O2S/c1-15-20(14-29-32-26(28)37)25(34(33-15)18-5-3-2-4-6-18)36-19-10-7-16(8-11-19)24-30-21-12-9-17(23(27)35)13-22(21)31-24/h2-14H,1H3,(H2,27,35)(H,30,31)(H3,28,32,37)/b29-14+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Centre
Curated by ChEMBL
| Assay Description
Inhibition of Chk2 (unknown origin) by spectrophotometric analysis |
Eur J Med Chem 144: 859-873 (2018)
Article DOI: 10.1016/j.ejmech.2017.12.023
BindingDB Entry DOI: 10.7270/Q2KD21F1 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human)) | BDBM50163251
(2-(4-(4-hydroxyphenylthio)phenyl)-1H-benzo[d]imida...)Show SMILES NC(=O)c1ccc2nc([nH]c2c1)-c1ccc(Sc2ccc(O)cc2)cc1 Show InChI InChI=1S/C20H15N3O2S/c21-19(25)13-3-10-17-18(11-13)23-20(22-17)12-1-6-15(7-2-12)26-16-8-4-14(24)5-9-16/h1-11,24H,(H2,21,25)(H,22,23) | PDB
MMDB
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| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Centre
Curated by ChEMBL
| Assay Description
Inhibition of Chk2 (unknown origin) by spectrophotometric analysis |
Eur J Med Chem 144: 859-873 (2018)
Article DOI: 10.1016/j.ejmech.2017.12.023
BindingDB Entry DOI: 10.7270/Q2KD21F1 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human)) | BDBM50291374
(CHEMBL4167099)Show SMILES Cc1nn(c(Oc2ccc(cc2)-c2nc3cc(ccc3[nH]2)[N+]([O-])=O)c1\C=N\Nc1ccc(cc1)[N+]([O-])=O)-c1ccccc1 Show InChI InChI=1S/C30H22N8O5/c1-19-26(18-31-34-21-9-11-23(12-10-21)37(39)40)30(36(35-19)22-5-3-2-4-6-22)43-25-14-7-20(8-15-25)29-32-27-16-13-24(38(41)42)17-28(27)33-29/h2-18,34H,1H3,(H,32,33)/b31-18+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Centre
Curated by ChEMBL
| Assay Description
Inhibition of Chk2 (unknown origin) by spectrophotometric analysis |
Eur J Med Chem 144: 859-873 (2018)
Article DOI: 10.1016/j.ejmech.2017.12.023
BindingDB Entry DOI: 10.7270/Q2KD21F1 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human)) | BDBM50291419
(CHEMBL4173942)Show SMILES Cc1nn(c(Sc2ccc(cc2)-c2nc3cc(ccc3[nH]2)[N+]([O-])=O)c1\C=N\NC(N)=O)-c1ccccc1 Show InChI InChI=1S/C25H20N8O3S/c1-15-20(14-27-30-25(26)34)24(32(31-15)17-5-3-2-4-6-17)37-19-10-7-16(8-11-19)23-28-21-12-9-18(33(35)36)13-22(21)29-23/h2-14H,1H3,(H,28,29)(H3,26,30,34)/b27-14+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Centre
Curated by ChEMBL
| Assay Description
Inhibition of Chk2 (unknown origin) by spectrophotometric analysis |
Eur J Med Chem 144: 859-873 (2018)
Article DOI: 10.1016/j.ejmech.2017.12.023
BindingDB Entry DOI: 10.7270/Q2KD21F1 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human)) | BDBM50291375
(CHEMBL4162573)Show SMILES COc1ccc(N\N=C\c2c(C)nn(c2Oc2ccc(cc2)-c2nc3cc(ccc3[nH]2)[N+]([O-])=O)-c2ccccc2)cc1 Show InChI InChI=1S/C31H25N7O4/c1-20-27(19-32-35-22-10-15-25(41-2)16-11-22)31(37(36-20)23-6-4-3-5-7-23)42-26-13-8-21(9-14-26)30-33-28-17-12-24(38(39)40)18-29(28)34-30/h3-19,35H,1-2H3,(H,33,34)/b32-19+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Centre
Curated by ChEMBL
| Assay Description
Inhibition of Chk2 (unknown origin) by spectrophotometric analysis |
Eur J Med Chem 144: 859-873 (2018)
Article DOI: 10.1016/j.ejmech.2017.12.023
BindingDB Entry DOI: 10.7270/Q2KD21F1 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human)) | BDBM50291407
(CHEMBL4176212)Show SMILES Cc1nn(c(Oc2ccc(cc2)-c2nc3cc(ccc3[nH]2)C(O)=O)c1\C=N\Nc1ccc(cc1)[N+]([O-])=O)-c1ccccc1 Show InChI InChI=1S/C31H23N7O5/c1-19-26(18-32-35-22-10-12-24(13-11-22)38(41)42)30(37(36-19)23-5-3-2-4-6-23)43-25-14-7-20(8-15-25)29-33-27-16-9-21(31(39)40)17-28(27)34-29/h2-18,35H,1H3,(H,33,34)(H,39,40)/b32-18+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
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AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Centre
Curated by ChEMBL
| Assay Description
Inhibition of Chk2 (unknown origin) by spectrophotometric analysis |
Eur J Med Chem 144: 859-873 (2018)
Article DOI: 10.1016/j.ejmech.2017.12.023
BindingDB Entry DOI: 10.7270/Q2KD21F1 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human)) | BDBM50291377
(CHEMBL4175850)Show SMILES Cc1nn(c(Sc2ccc(cc2)-c2nc3cc(ccc3[nH]2)C(N)=O)c1\C=N\NC(N)=O)-c1ccccc1 Show InChI InChI=1S/C26H22N8O2S/c1-15-20(14-29-32-26(28)36)25(34(33-15)18-5-3-2-4-6-18)37-19-10-7-16(8-11-19)24-30-21-12-9-17(23(27)35)13-22(21)31-24/h2-14H,1H3,(H2,27,35)(H,30,31)(H3,28,32,36)/b29-14+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Centre
Curated by ChEMBL
| Assay Description
Inhibition of Chk2 (unknown origin) by spectrophotometric analysis |
Eur J Med Chem 144: 859-873 (2018)
Article DOI: 10.1016/j.ejmech.2017.12.023
BindingDB Entry DOI: 10.7270/Q2KD21F1 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human)) | BDBM50291373
(CHEMBL4159185)Show SMILES Cc1nn(c(Oc2ccc(cc2)-c2nc3cc(ccc3[nH]2)[N+]([O-])=O)c1\C=N\NC(N)=O)-c1ccccc1 Show InChI InChI=1S/C25H20N8O4/c1-15-20(14-27-30-25(26)34)24(32(31-15)17-5-3-2-4-6-17)37-19-10-7-16(8-11-19)23-28-21-12-9-18(33(35)36)13-22(21)29-23/h2-14H,1H3,(H,28,29)(H3,26,30,34)/b27-14+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Centre
Curated by ChEMBL
| Assay Description
Inhibition of Chk2 (unknown origin) by spectrophotometric analysis |
Eur J Med Chem 144: 859-873 (2018)
Article DOI: 10.1016/j.ejmech.2017.12.023
BindingDB Entry DOI: 10.7270/Q2KD21F1 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human)) | BDBM50291371
(CHEMBL4169439)Show SMILES CC(=O)N\N=C\c1c(C)nn(c1Oc1ccc(cc1)-c1nc2cc(ccc2[nH]1)[N+]([O-])=O)-c1ccccc1 Show InChI InChI=1S/C26H21N7O4/c1-16-22(15-27-30-17(2)34)26(32(31-16)19-6-4-3-5-7-19)37-21-11-8-18(9-12-21)25-28-23-13-10-20(33(35)36)14-24(23)29-25/h3-15H,1-2H3,(H,28,29)(H,30,34)/b27-15+ | PDB
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UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Centre
Curated by ChEMBL
| Assay Description
Inhibition of Chk2 (unknown origin) by spectrophotometric analysis |
Eur J Med Chem 144: 859-873 (2018)
Article DOI: 10.1016/j.ejmech.2017.12.023
BindingDB Entry DOI: 10.7270/Q2KD21F1 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human)) | BDBM50291385
(CHEMBL4169171)Show SMILES CC(=O)N\N=C\c1c(C)nn(c1Oc1ccc(cc1)-c1nc2cc(ccc2[nH]1)C(O)=O)-c1ccccc1 Show InChI InChI=1S/C27H22N6O4/c1-16-22(15-28-31-17(2)34)26(33(32-16)20-6-4-3-5-7-20)37-21-11-8-18(9-12-21)25-29-23-13-10-19(27(35)36)14-24(23)30-25/h3-15H,1-2H3,(H,29,30)(H,31,34)(H,35,36)/b28-15+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Centre
Curated by ChEMBL
| Assay Description
Inhibition of Chk2 (unknown origin) by spectrophotometric analysis |
Eur J Med Chem 144: 859-873 (2018)
Article DOI: 10.1016/j.ejmech.2017.12.023
BindingDB Entry DOI: 10.7270/Q2KD21F1 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human)) | BDBM50291378
(CHEMBL4168756)Show SMILES CC(=O)N\N=C\c1c(C)nn(c1Oc1ccc(cc1)-c1nc2cc(ccc2[nH]1)C(N)=O)-c1ccccc1 Show InChI InChI=1S/C27H23N7O3/c1-16-22(15-29-32-17(2)35)27(34(33-16)20-6-4-3-5-7-20)37-21-11-8-18(9-12-21)26-30-23-13-10-19(25(28)36)14-24(23)31-26/h3-15H,1-2H3,(H2,28,36)(H,30,31)(H,32,35)/b29-15+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Centre
Curated by ChEMBL
| Assay Description
Inhibition of Chk2 (unknown origin) by spectrophotometric analysis |
Eur J Med Chem 144: 859-873 (2018)
Article DOI: 10.1016/j.ejmech.2017.12.023
BindingDB Entry DOI: 10.7270/Q2KD21F1 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human)) | BDBM50291382
(CHEMBL4166813)Show SMILES COc1ccc(N\N=C\c2c(C)nn(c2Oc2ccc(cc2)-c2nc3cc(ccc3[nH]2)C(N)=O)-c2ccccc2)cc1 Show InChI InChI=1S/C32H27N7O3/c1-20-27(19-34-37-23-11-15-25(41-2)16-12-23)32(39(38-20)24-6-4-3-5-7-24)42-26-13-8-21(9-14-26)31-35-28-17-10-22(30(33)40)18-29(28)36-31/h3-19,37H,1-2H3,(H2,33,40)(H,35,36)/b34-19+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Centre
Curated by ChEMBL
| Assay Description
Inhibition of Chk2 (unknown origin) by spectrophotometric analysis |
Eur J Med Chem 144: 859-873 (2018)
Article DOI: 10.1016/j.ejmech.2017.12.023
BindingDB Entry DOI: 10.7270/Q2KD21F1 |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human)) | BDBM50291409
(CHEMBL4166017)Show SMILES Cc1nn(c(Oc2ccc(cc2)-c2nc3cc(ccc3[nH]2)C(O)=O)c1\C=N\Nc1ccccc1)-c1ccccc1 Show InChI InChI=1S/C31H24N6O3/c1-20-26(19-32-35-23-8-4-2-5-9-23)30(37(36-20)24-10-6-3-7-11-24)40-25-15-12-21(13-16-25)29-33-27-17-14-22(31(38)39)18-28(27)34-29/h2-19,35H,1H3,(H,33,34)(H,38,39)/b32-19+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Centre
Curated by ChEMBL
| Assay Description
Inhibition of Chk2 (unknown origin) by spectrophotometric analysis |
Eur J Med Chem 144: 859-873 (2018)
Article DOI: 10.1016/j.ejmech.2017.12.023
BindingDB Entry DOI: 10.7270/Q2KD21F1 |
More data for this
Ligand-Target Pair | |
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