Found 15 hits Enz. Inhib. hit(s) with all data for entry = 50042151 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421355
(CHEMBL289955)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@](C)(CC(C)O2)OC)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:48.53,12.12,wD:22.23,10.9,30.32,37.39,48.52,12.18,44.47,c:43,(-2.61,-6.72,;-2.99,-5.23,;-1.89,-4.14,;-2.12,-5.65,;-.83,-6.49,;-.86,-8.03,;.5,-5.68,;1.89,-6.35,;.31,-4.15,;1.64,-4.91,;2.97,-5.68,;2.97,-7.22,;4.3,-7.99,;2.96,-8.75,;5.63,-7.22,;5.63,-5.68,;6.96,-4.91,;4.3,-4.91,;4.7,-9.47,;3.6,-10.55,;1.75,-3.55,;3.03,-4.39,;1.75,-1.99,;3.03,-1.15,;4.37,-.38,;5.69,-1.15,;7.02,-.38,;8.36,-1.15,;7.02,1.16,;5.69,1.93,;4.37,1.16,;3.03,1.93,;5.69,3.47,;4.36,4.24,;7.03,4.24,;7.03,5.78,;8.36,3.47,;.33,-1.38,;1.42,-.28,;.54,.13,;-.75,.97,;-.74,2.51,;-2.07,.16,;-.97,-.93,;-1.86,-1.36,;-3.2,-.59,;-3.29,-1.97,;-4.57,-1.1,;-3.31,-3.51,;-4.08,-4.84,;-4.8,-3.1,;-5.9,-4.18,)| Show InChI InChI=1S/C40H69NO11/c1-16-29-40(12,46-15)34(43)25(7)32-22(4)18-39(11,52-32)35(51-37-31(42)28(17-23(5)48-37)41(13)21(2)3)26(8)33(27(9)36(44)49-29)50-30-20-38(10,45-14)19-24(6)47-30/h21,23-31,33,35,37,42H,16-20H2,1-15H3/t23?,24?,25-,26?,27?,28?,29?,30-,31+,33?,35+,37?,38-,39-,40+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis... |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421358
(CHEMBL45141)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@](C)(CC(C)O2)OC)C(C)[C@@H](OC2CC(CC(C)O2)N(C)C(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:47.52,12.12,wD:10.9,22.23,36.38,47.51,12.18,43.46,c:42,(-2.61,-6.72,;-2.99,-5.23,;-1.89,-4.14,;-2.12,-5.65,;-.83,-6.49,;-.86,-8.03,;.5,-5.68,;1.89,-6.35,;.31,-4.15,;1.64,-4.91,;2.97,-5.68,;2.97,-7.22,;4.3,-7.99,;2.96,-8.75,;5.63,-7.22,;5.63,-5.68,;6.96,-4.91,;4.3,-4.91,;4.7,-9.47,;3.6,-10.55,;1.75,-3.55,;3.03,-4.39,;1.75,-1.99,;3.03,-1.15,;4.37,-.38,;4.37,1.16,;5.69,1.93,;7.02,1.16,;7.02,-.38,;8.36,-1.15,;5.69,-1.15,;5.69,3.47,;4.36,4.24,;7.03,4.24,;7.03,5.78,;8.36,3.47,;.33,-1.38,;1.42,-.28,;.54,.13,;-.75,.97,;-.74,2.51,;-2.07,.16,;-.97,-.93,;-1.86,-1.36,;-3.2,-.59,;-3.29,-1.97,;-4.57,-1.1,;-3.31,-3.51,;-4.08,-4.84,;-4.8,-3.1,;-5.9,-4.18,)| Show InChI InChI=1S/C40H69NO10/c1-16-30-40(12,45-15)35(42)26(7)33-23(4)19-39(11,51-33)36(50-31-18-29(17-24(5)46-31)41(13)22(2)3)27(8)34(28(9)37(43)48-30)49-32-21-38(10,44-14)20-25(6)47-32/h22,24-32,34,36H,16-21H2,1-15H3/t24?,25?,26-,27?,28?,29?,30?,31?,32-,34?,36+,38-,39-,40+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenate |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421357
(CHEMBL297168)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@](C)(CC(C)O2)OC)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:46.51,12.12,wD:22.23,10.9,30.32,35.37,46.50,12.18,42.45,c:41,(-2.61,-6.72,;-2.99,-5.23,;-1.89,-4.14,;-2.12,-5.65,;-.83,-6.49,;-.86,-8.03,;.5,-5.68,;1.89,-6.35,;.31,-4.15,;1.64,-4.91,;2.97,-5.68,;2.97,-7.22,;4.3,-7.99,;2.96,-8.75,;5.63,-7.22,;5.63,-5.68,;6.96,-4.91,;4.3,-4.91,;4.7,-9.47,;3.6,-10.55,;1.75,-3.55,;3.03,-4.39,;1.75,-1.99,;3.03,-1.15,;4.37,-.38,;5.69,-1.15,;7.02,-.38,;8.36,-1.15,;7.02,1.16,;5.69,1.93,;4.37,1.16,;3.03,1.93,;5.69,3.47,;4.36,4.24,;7.03,4.24,;.33,-1.38,;1.42,-.28,;.54,.13,;-.75,.97,;-.74,2.51,;-2.07,.16,;-.97,-.93,;-1.86,-1.36,;-3.2,-.59,;-3.29,-1.97,;-4.57,-1.1,;-3.31,-3.51,;-4.08,-4.84,;-4.8,-3.1,;-5.9,-4.18,)| Show InChI InChI=1S/C38H65NO11/c1-15-27-38(10,44-14)32(41)23(5)30-20(2)17-37(9,50-30)33(49-35-29(40)26(39(11)12)16-21(3)46-35)24(6)31(25(7)34(42)47-27)48-28-19-36(8,43-13)18-22(4)45-28/h21-29,31,33,35,40H,15-19H2,1-14H3/t21?,22?,23-,24?,25?,26?,27?,28-,29+,31?,33+,35?,36-,37-,38+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenate |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421355
(CHEMBL289955)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@](C)(CC(C)O2)OC)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:48.53,12.12,wD:22.23,10.9,30.32,37.39,48.52,12.18,44.47,c:43,(-2.61,-6.72,;-2.99,-5.23,;-1.89,-4.14,;-2.12,-5.65,;-.83,-6.49,;-.86,-8.03,;.5,-5.68,;1.89,-6.35,;.31,-4.15,;1.64,-4.91,;2.97,-5.68,;2.97,-7.22,;4.3,-7.99,;2.96,-8.75,;5.63,-7.22,;5.63,-5.68,;6.96,-4.91,;4.3,-4.91,;4.7,-9.47,;3.6,-10.55,;1.75,-3.55,;3.03,-4.39,;1.75,-1.99,;3.03,-1.15,;4.37,-.38,;5.69,-1.15,;7.02,-.38,;8.36,-1.15,;7.02,1.16,;5.69,1.93,;4.37,1.16,;3.03,1.93,;5.69,3.47,;4.36,4.24,;7.03,4.24,;7.03,5.78,;8.36,3.47,;.33,-1.38,;1.42,-.28,;.54,.13,;-.75,.97,;-.74,2.51,;-2.07,.16,;-.97,-.93,;-1.86,-1.36,;-3.2,-.59,;-3.29,-1.97,;-4.57,-1.1,;-3.31,-3.51,;-4.08,-4.84,;-4.8,-3.1,;-5.9,-4.18,)| Show InChI InChI=1S/C40H69NO11/c1-16-29-40(12,46-15)34(43)25(7)32-22(4)18-39(11,52-32)35(51-37-31(42)28(17-23(5)48-37)41(13)21(2)3)26(8)33(27(9)36(44)49-29)50-30-20-38(10,45-14)19-24(6)47-30/h21,23-31,33,35,37,42H,16-20H2,1-15H3/t23?,24?,25-,26?,27?,28?,29?,30-,31+,33?,35+,37?,38-,39-,40+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenate |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421354
(CHEMBL26966)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)CC)[C@]2(C)CC(C)=C(O2)[C@H](C)[C@@H](O)[C@]1(C)O |wU:48.53,12.12,wD:23.24,10.9,31.33,46.49,12.13,16.16,37.39,48.52,44.47,c:43,(-2.8,-3.98,;-2.77,-2.44,;-1.44,-1.68,;-1.44,-3.21,;-.13,-3.98,;-.13,-5.53,;1.22,-3.21,;2.56,-3.98,;1.22,-1.68,;2.53,-2.46,;3.87,-3.23,;3.87,-4.75,;5.2,-5.53,;3.84,-6.29,;6.53,-6.3,;6.53,-7.84,;6.53,-4.78,;7.86,-5.54,;6.53,-3.23,;7.89,-2.46,;5.2,-2.46,;2.56,-.91,;3.89,-1.68,;2.56,.65,;3.89,1.43,;5.22,2.2,;6.58,1.44,;7.89,2.21,;9.24,1.44,;7.89,3.76,;6.55,4.53,;5.22,3.76,;3.87,4.5,;6.55,6.07,;5.22,6.83,;7.89,6.84,;9.22,6.07,;1.22,1.4,;2.56,2.17,;1.22,2.95,;-.11,3.72,;-.13,5.26,;-1.44,2.95,;-.67,1.61,;-1.44,1.4,;-2.94,1.8,;-2.77,.63,;-4.32,.63,;-2.77,-.91,;-3.87,-2.01,;-4.32,-.91,)| Show InChI InChI=1S/C38H67NO12/c1-14-26-38(11,44)31(41)21(5)29-19(3)17-37(10,51-29)33(50-35-28(40)25(39(12)15-2)16-20(4)46-35)22(6)30(23(7)34(43)48-26)49-27-18-36(9,45-13)32(42)24(8)47-27/h20-28,30-33,35,40-42,44H,14-18H2,1-13H3/t20?,21-,22?,23?,24?,25?,26?,27-,28+,30?,31+,32-,33+,35?,36+,37-,38+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenate |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421356
(CHEMBL43313)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@](C)(CC(C)O2)OC)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)CC)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:47.52,12.12,wD:22.23,10.9,30.32,36.38,47.51,12.18,43.46,c:42,(-2.61,-6.72,;-2.99,-5.23,;-1.89,-4.14,;-2.12,-5.65,;-.83,-6.49,;-.86,-8.03,;.5,-5.68,;1.89,-6.35,;.31,-4.15,;1.64,-4.91,;2.97,-5.68,;2.97,-7.22,;4.3,-7.99,;2.96,-8.75,;5.63,-7.22,;5.63,-5.68,;6.96,-4.91,;4.3,-4.91,;4.7,-9.47,;3.6,-10.55,;1.75,-3.55,;3.03,-4.39,;1.75,-1.99,;3.03,-1.15,;4.37,-.38,;5.69,-1.15,;7.02,-.38,;8.36,-1.15,;7.02,1.16,;5.69,1.93,;4.37,1.16,;3.03,1.93,;5.69,3.47,;4.36,4.24,;7.03,4.24,;7.03,5.78,;.33,-1.38,;1.42,-.28,;.54,.13,;-.75,.97,;-.74,2.51,;-2.07,.16,;-.97,-.93,;-1.86,-1.36,;-3.2,-.59,;-3.29,-1.97,;-4.57,-1.1,;-3.31,-3.51,;-4.08,-4.84,;-4.8,-3.1,;-5.9,-4.18,)| Show InChI InChI=1S/C39H67NO11/c1-15-28-39(11,45-14)33(42)24(6)31-21(3)18-38(10,51-31)34(50-36-30(41)27(40(12)16-2)17-22(4)47-36)25(7)32(26(8)35(43)48-28)49-29-20-37(9,44-13)19-23(5)46-29/h22-30,32,34,36,41H,15-20H2,1-14H3/t22?,23?,24-,25?,26?,27?,28?,29-,30+,32?,34+,36?,37-,38-,39+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenate |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421349
(CHEMBL265495)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)CC)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:48.53,12.12,wD:23.24,10.9,31.33,12.13,16.16,37.39,48.52,44.47,c:43,(-1.68,-4.26,;-1.66,-2.72,;-.32,-1.96,;-.32,-3.49,;.99,-4.26,;.99,-5.8,;2.32,-3.49,;3.67,-4.26,;2.34,-1.96,;3.66,-2.74,;4.99,-3.51,;4.99,-5.03,;6.31,-5.81,;4.96,-6.57,;7.65,-6.58,;7.65,-8.12,;7.65,-5.05,;8.99,-5.82,;7.65,-3.51,;8.99,-2.74,;6.32,-2.74,;3.67,-1.19,;5.01,-1.96,;3.68,.37,;5.01,1.15,;6.34,1.92,;7.68,1.16,;9.01,1.93,;10.34,1.16,;9.01,3.48,;7.67,4.25,;6.32,3.46,;4.99,4.25,;7.65,5.79,;6.32,6.55,;9,6.56,;8.99,8.1,;2.35,1.12,;3.68,1.89,;2.35,2.67,;1.01,3.44,;1.01,4.98,;-.32,2.67,;.45,1.33,;-.32,1.12,;-1.82,1.52,;-1.65,.35,;-3.2,.35,;-1.65,-1.19,;-2.75,-2.29,;-3.2,-1.19,;-3.97,-2.5,)| Show InChI InChI=1S/C39H67NO12/c1-15-27-39(11,46-14)32(42)22(5)30-20(3)18-38(10,52-30)34(51-36-29(41)26(40(12)16-2)17-21(4)47-36)23(6)31(24(7)35(44)49-27)50-28-19-37(9,45-13)33(43)25(8)48-28/h21-29,31,33-34,36,41,43H,15-19H2,1-14H3/t21?,22-,23?,24?,25?,26?,27?,28-,29+,31?,33-,34+,36?,37+,38-,39+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis... |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421356
(CHEMBL43313)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@](C)(CC(C)O2)OC)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)CC)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:47.52,12.12,wD:22.23,10.9,30.32,36.38,47.51,12.18,43.46,c:42,(-2.61,-6.72,;-2.99,-5.23,;-1.89,-4.14,;-2.12,-5.65,;-.83,-6.49,;-.86,-8.03,;.5,-5.68,;1.89,-6.35,;.31,-4.15,;1.64,-4.91,;2.97,-5.68,;2.97,-7.22,;4.3,-7.99,;2.96,-8.75,;5.63,-7.22,;5.63,-5.68,;6.96,-4.91,;4.3,-4.91,;4.7,-9.47,;3.6,-10.55,;1.75,-3.55,;3.03,-4.39,;1.75,-1.99,;3.03,-1.15,;4.37,-.38,;5.69,-1.15,;7.02,-.38,;8.36,-1.15,;7.02,1.16,;5.69,1.93,;4.37,1.16,;3.03,1.93,;5.69,3.47,;4.36,4.24,;7.03,4.24,;7.03,5.78,;.33,-1.38,;1.42,-.28,;.54,.13,;-.75,.97,;-.74,2.51,;-2.07,.16,;-.97,-.93,;-1.86,-1.36,;-3.2,-.59,;-3.29,-1.97,;-4.57,-1.1,;-3.31,-3.51,;-4.08,-4.84,;-4.8,-3.1,;-5.9,-4.18,)| Show InChI InChI=1S/C39H67NO11/c1-15-28-39(11,45-14)33(42)24(6)31-21(3)18-38(10,51-31)34(50-36-30(41)27(40(12)16-2)17-22(4)47-36)25(7)32(26(8)35(43)48-28)49-29-20-37(9,44-13)19-23(5)46-29/h22-30,32,34,36,41H,15-20H2,1-14H3/t22?,23?,24-,25?,26?,27?,28?,29-,30+,32?,34+,36?,37-,38-,39+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis... |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421357
(CHEMBL297168)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@](C)(CC(C)O2)OC)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:46.51,12.12,wD:22.23,10.9,30.32,35.37,46.50,12.18,42.45,c:41,(-2.61,-6.72,;-2.99,-5.23,;-1.89,-4.14,;-2.12,-5.65,;-.83,-6.49,;-.86,-8.03,;.5,-5.68,;1.89,-6.35,;.31,-4.15,;1.64,-4.91,;2.97,-5.68,;2.97,-7.22,;4.3,-7.99,;2.96,-8.75,;5.63,-7.22,;5.63,-5.68,;6.96,-4.91,;4.3,-4.91,;4.7,-9.47,;3.6,-10.55,;1.75,-3.55,;3.03,-4.39,;1.75,-1.99,;3.03,-1.15,;4.37,-.38,;5.69,-1.15,;7.02,-.38,;8.36,-1.15,;7.02,1.16,;5.69,1.93,;4.37,1.16,;3.03,1.93,;5.69,3.47,;4.36,4.24,;7.03,4.24,;.33,-1.38,;1.42,-.28,;.54,.13,;-.75,.97,;-.74,2.51,;-2.07,.16,;-.97,-.93,;-1.86,-1.36,;-3.2,-.59,;-3.29,-1.97,;-4.57,-1.1,;-3.31,-3.51,;-4.08,-4.84,;-4.8,-3.1,;-5.9,-4.18,)| Show InChI InChI=1S/C38H65NO11/c1-15-27-38(10,44-14)32(41)23(5)30-20(2)17-37(9,50-30)33(49-35-29(40)26(39(11)12)16-21(3)46-35)24(6)31(25(7)34(42)47-27)48-28-19-36(8,43-13)18-22(4)45-28/h21-29,31,33,35,40H,15-19H2,1-14H3/t21?,22?,23-,24?,25?,26?,27?,28-,29+,31?,33+,35?,36-,37-,38+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis... |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421351
(CHEMBL27424)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:49.54,12.12,wD:23.24,10.9,31.33,12.13,16.16,38.40,49.53,45.48,c:44,(-1.28,-6.37,;-1.26,-4.82,;.08,-4.07,;.08,-5.6,;1.39,-6.36,;1.39,-7.9,;2.72,-5.6,;4.07,-6.37,;2.74,-4.07,;4.05,-4.84,;5.39,-5.61,;5.39,-7.14,;6.71,-7.91,;5.36,-8.67,;8.04,-8.68,;8.04,-10.23,;8.05,-7.15,;9.38,-7.93,;8.05,-5.61,;9.38,-4.84,;6.72,-4.84,;4.07,-3.3,;5.41,-4.07,;4.08,-1.74,;5.41,-.96,;6.74,-.17,;8.07,-.94,;9.41,-.17,;10.74,-.94,;9.41,1.37,;8.07,2.14,;6.72,1.36,;5.39,2.13,;8.05,3.69,;6.72,4.44,;9.4,4.46,;9.38,6,;10.73,3.69,;2.74,-.98,;4.08,-.21,;2.74,.56,;1.41,1.33,;1.4,2.88,;.08,.56,;.85,-.77,;.08,-.98,;-1.42,-.58,;-1.25,-1.75,;-2.8,-1.75,;-1.25,-3.3,;-2.35,-4.4,;-2.8,-3.3,;-3.58,-4.61,)| Show InChI InChI=1S/C40H69NO12/c1-16-28-40(12,47-15)33(43)23(6)31-21(4)18-39(11,53-31)35(52-37-30(42)27(17-22(5)48-37)41(13)20(2)3)24(7)32(25(8)36(45)50-28)51-29-19-38(10,46-14)34(44)26(9)49-29/h20,22-30,32,34-35,37,42,44H,16-19H2,1-15H3/t22?,23-,24?,25?,26?,27?,28?,29-,30+,32?,34-,35+,37?,38+,39-,40+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenate |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421349
(CHEMBL265495)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)CC)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:48.53,12.12,wD:23.24,10.9,31.33,12.13,16.16,37.39,48.52,44.47,c:43,(-1.68,-4.26,;-1.66,-2.72,;-.32,-1.96,;-.32,-3.49,;.99,-4.26,;.99,-5.8,;2.32,-3.49,;3.67,-4.26,;2.34,-1.96,;3.66,-2.74,;4.99,-3.51,;4.99,-5.03,;6.31,-5.81,;4.96,-6.57,;7.65,-6.58,;7.65,-8.12,;7.65,-5.05,;8.99,-5.82,;7.65,-3.51,;8.99,-2.74,;6.32,-2.74,;3.67,-1.19,;5.01,-1.96,;3.68,.37,;5.01,1.15,;6.34,1.92,;7.68,1.16,;9.01,1.93,;10.34,1.16,;9.01,3.48,;7.67,4.25,;6.32,3.46,;4.99,4.25,;7.65,5.79,;6.32,6.55,;9,6.56,;8.99,8.1,;2.35,1.12,;3.68,1.89,;2.35,2.67,;1.01,3.44,;1.01,4.98,;-.32,2.67,;.45,1.33,;-.32,1.12,;-1.82,1.52,;-1.65,.35,;-3.2,.35,;-1.65,-1.19,;-2.75,-2.29,;-3.2,-1.19,;-3.97,-2.5,)| Show InChI InChI=1S/C39H67NO12/c1-15-27-39(11,46-14)32(42)22(5)30-20(3)18-38(10,52-30)34(51-36-29(41)26(40(12)16-2)17-21(4)47-36)23(6)31(24(7)35(44)49-27)50-28-19-37(9,45-13)33(43)25(8)48-28/h21-29,31,33-34,36,41,43H,15-19H2,1-14H3/t21?,22-,23?,24?,25?,26?,27?,28-,29+,31?,33-,34+,36?,37+,38-,39+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis... |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421351
(CHEMBL27424)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:49.54,12.12,wD:23.24,10.9,31.33,12.13,16.16,38.40,49.53,45.48,c:44,(-1.28,-6.37,;-1.26,-4.82,;.08,-4.07,;.08,-5.6,;1.39,-6.36,;1.39,-7.9,;2.72,-5.6,;4.07,-6.37,;2.74,-4.07,;4.05,-4.84,;5.39,-5.61,;5.39,-7.14,;6.71,-7.91,;5.36,-8.67,;8.04,-8.68,;8.04,-10.23,;8.05,-7.15,;9.38,-7.93,;8.05,-5.61,;9.38,-4.84,;6.72,-4.84,;4.07,-3.3,;5.41,-4.07,;4.08,-1.74,;5.41,-.96,;6.74,-.17,;8.07,-.94,;9.41,-.17,;10.74,-.94,;9.41,1.37,;8.07,2.14,;6.72,1.36,;5.39,2.13,;8.05,3.69,;6.72,4.44,;9.4,4.46,;9.38,6,;10.73,3.69,;2.74,-.98,;4.08,-.21,;2.74,.56,;1.41,1.33,;1.4,2.88,;.08,.56,;.85,-.77,;.08,-.98,;-1.42,-.58,;-1.25,-1.75,;-2.8,-1.75,;-1.25,-3.3,;-2.35,-4.4,;-2.8,-3.3,;-3.58,-4.61,)| Show InChI InChI=1S/C40H69NO12/c1-16-28-40(12,47-15)33(43)23(6)31-21(4)18-39(11,53-31)35(52-37-30(42)27(17-22(5)48-37)41(13)20(2)3)24(7)32(25(8)36(45)50-28)51-29-19-38(10,46-14)34(44)26(9)49-29/h20,22-30,32,34-35,37,42,44H,16-19H2,1-15H3/t22?,23-,24?,25?,26?,27?,28?,29-,30+,32?,34-,35+,37?,38+,39-,40+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis... |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421350
(CHEMBL27419)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:47.52,12.12,wD:23.24,10.9,31.33,12.13,16.16,36.38,47.51,43.46,c:42,(-1.7,-4.4,;-1.68,-2.85,;-.34,-2.09,;-.34,-3.62,;.97,-4.38,;.97,-5.92,;2.3,-3.62,;3.66,-4.4,;2.32,-2.09,;3.63,-2.86,;4.96,-3.63,;4.96,-5.17,;6.3,-5.94,;4.94,-6.69,;7.63,-6.71,;7.63,-8.25,;7.63,-5.18,;8.96,-5.95,;7.63,-3.63,;8.96,-2.86,;6.3,-2.86,;3.66,-1.32,;4.99,-2.09,;3.66,.23,;4.99,1.02,;6.32,1.79,;7.65,1.03,;8.99,1.8,;10.32,1.03,;8.99,3.34,;7.65,4.13,;6.3,3.34,;4.96,4.11,;7.63,5.66,;8.99,6.43,;6.3,6.42,;2.32,1,;3.66,1.77,;2.32,2.54,;.99,3.31,;.99,4.86,;-.34,2.54,;.43,1.21,;-.34,1,;-1.84,1.39,;-1.68,.23,;-3.22,.23,;-1.68,-1.32,;-2.77,-2.42,;-3.22,-1.32,;-3.99,-2.63,)| Show InChI InChI=1S/C38H65NO12/c1-15-26-38(10,45-14)31(41)21(4)29-19(2)17-37(9,51-29)33(50-35-28(40)25(39(11)12)16-20(3)46-35)22(5)30(23(6)34(43)48-26)49-27-18-36(8,44-13)32(42)24(7)47-27/h20-28,30,32-33,35,40,42H,15-18H2,1-14H3/t20?,21-,22?,23?,24?,25?,26?,27-,28+,30?,32-,33+,35?,36+,37-,38+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 8.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis... |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421350
(CHEMBL27419)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC |wU:47.52,12.12,wD:23.24,10.9,31.33,12.13,16.16,36.38,47.51,43.46,c:42,(-1.7,-4.4,;-1.68,-2.85,;-.34,-2.09,;-.34,-3.62,;.97,-4.38,;.97,-5.92,;2.3,-3.62,;3.66,-4.4,;2.32,-2.09,;3.63,-2.86,;4.96,-3.63,;4.96,-5.17,;6.3,-5.94,;4.94,-6.69,;7.63,-6.71,;7.63,-8.25,;7.63,-5.18,;8.96,-5.95,;7.63,-3.63,;8.96,-2.86,;6.3,-2.86,;3.66,-1.32,;4.99,-2.09,;3.66,.23,;4.99,1.02,;6.32,1.79,;7.65,1.03,;8.99,1.8,;10.32,1.03,;8.99,3.34,;7.65,4.13,;6.3,3.34,;4.96,4.11,;7.63,5.66,;8.99,6.43,;6.3,6.42,;2.32,1,;3.66,1.77,;2.32,2.54,;.99,3.31,;.99,4.86,;-.34,2.54,;.43,1.21,;-.34,1,;-1.84,1.39,;-1.68,.23,;-3.22,.23,;-1.68,-1.32,;-2.77,-2.42,;-3.22,-1.32,;-3.99,-2.63,)| Show InChI InChI=1S/C38H65NO12/c1-15-26-38(10,45-14)31(41)21(4)29-19(2)17-37(9,51-29)33(50-35-28(40)25(39(11)12)16-20(3)46-35)22(5)30(23(6)34(43)48-26)49-27-18-36(8,44-13)32(42)24(7)47-27/h20-28,30,32-33,35,40,42H,15-18H2,1-14H3/t20?,21-,22?,23?,24?,25?,26?,27-,28+,30?,32-,33+,35?,36+,37-,38+/m0/s1 | Reactome pathway
KEGG
UniProtKB/TrEMBL
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 9.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenate |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
Motilin receptor
(Oryctolagus cuniculus) | BDBM50421354
(CHEMBL26966)Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)CC)[C@]2(C)CC(C)=C(O2)[C@H](C)[C@@H](O)[C@]1(C)O |wU:48.53,12.12,wD:23.24,10.9,31.33,46.49,12.13,16.16,37.39,48.52,44.47,c:43,(-2.8,-3.98,;-2.77,-2.44,;-1.44,-1.68,;-1.44,-3.21,;-.13,-3.98,;-.13,-5.53,;1.22,-3.21,;2.56,-3.98,;1.22,-1.68,;2.53,-2.46,;3.87,-3.23,;3.87,-4.75,;5.2,-5.53,;3.84,-6.29,;6.53,-6.3,;6.53,-7.84,;6.53,-4.78,;7.86,-5.54,;6.53,-3.23,;7.89,-2.46,;5.2,-2.46,;2.56,-.91,;3.89,-1.68,;2.56,.65,;3.89,1.43,;5.22,2.2,;6.58,1.44,;7.89,2.21,;9.24,1.44,;7.89,3.76,;6.55,4.53,;5.22,3.76,;3.87,4.5,;6.55,6.07,;5.22,6.83,;7.89,6.84,;9.22,6.07,;1.22,1.4,;2.56,2.17,;1.22,2.95,;-.11,3.72,;-.13,5.26,;-1.44,2.95,;-.67,1.61,;-1.44,1.4,;-2.94,1.8,;-2.77,.63,;-4.32,.63,;-2.77,-.91,;-3.87,-2.01,;-4.32,-.91,)| Show InChI InChI=1S/C38H67NO12/c1-14-26-38(11,44)31(41)21(5)29-19(3)17-37(10,51-29)33(50-35-28(40)25(39(12)15-2)16-20(4)46-35)22(6)30(23(7)34(43)48-26)49-27-18-36(9,45-13)32(42)24(8)47-27/h20-28,30-33,35,40-42,44H,14-18H2,1-13H3/t20?,21-,22?,23?,24?,25?,26?,27-,28+,30?,31+,32-,33+,35?,36+,37-,38+/m0/s1 | Reactome pathway
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TBA
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis... |
Bioorg Med Chem Lett 4: 1649-1654 (1994)
Article DOI: 10.1016/S0960-894X(01)80583-7
BindingDB Entry DOI: 10.7270/Q2K075JS |
More data for this
Ligand-Target Pair | |
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