Compile Data Set for Download or QSAR

Found 58 hits Enz. Inhib. hit(s) with all data for entry = 50001766   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	0.0730	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at human PRB expressed in African green monkey CV1 cells				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at human GR assessed as reduction in dexamethasone-induced transactivation				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair				3D Structure (crystal)
Androgen receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at human AR assessed as reduction in DHT-induced transactivation				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Displacement of [1,2,6,7-3H]progesterone from recombinant human GST-tagged PGR LBD (678 to 933 residues) expressed in baculovirus-infected insect cel...				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM50118690 (3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...) Show SMILES CC1(C)OC(=O)Nc2ccc(cc12)-c1cc(F)cc(c1)C#N Show InChI InChI=1S/C17H13FN2O2/c1-17(2)14-8-11(3-4-15(14)20-16(21)22-17)12-5-10(9-19)6-13(18)7-12/h3-8H,1-2H3,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at human PRB expressed in African green monkey CV1 cells				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50367097 (CHEMBL4173799) Show SMILES Cc1cc(cc2c1n(C)c(=O)c1cc(F)ccc21)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C18H12F7NO2/c1-8-5-9(16(28,17(20,21)22)18(23,24)25)6-12-11-4-3-10(19)7-13(11)15(27)26(2)14(8)12/h3-7,28H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50367121 (CHEMBL4175249) Show SMILES Cc1cc(cc2c1[nH]c(=O)c1cc(F)ccc21)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H10F7NO2/c1-7-4-8(15(27,16(19,20)21)17(22,23)24)5-11-10-3-2-9(18)6-12(10)14(26)25-13(7)11/h2-6,27H,1H3,(H,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50203153 (CHEMBL3927163) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C19H14F3NO3S/c20-19(21,22)14-5-4-8-18(13-14)27(24,25)23-15-9-11-17(12-10-15)26-16-6-2-1-3-7-16/h1-13,23H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50355243 (CHEMBL1835836) Show SMILES Cn1c(ccc1-c1ccc2oc(=O)ccc2c1)C#N Show InChI InChI=1S/C15H10N2O2/c1-17-12(9-16)4-5-13(17)10-2-6-14-11(8-10)3-7-15(18)19-14/h2-8H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50367113 (CHEMBL4174942) Show SMILES OC(c1cc(F)c2[nH]c(=O)c3ccccc3c2c1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C16H8F7NO2/c17-11-6-7(14(26,15(18,19)20)16(21,22)23)5-10-8-3-1-2-4-9(8)13(25)24-12(10)11/h1-6,26H,(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50367097 (CHEMBL4173799) Show SMILES Cc1cc(cc2c1n(C)c(=O)c1cc(F)ccc21)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C18H12F7NO2/c1-8-5-9(16(28,17(20,21)22)18(23,24)25)6-12-11-4-3-10(19)7-13(11)15(27)26(2)14(8)12/h3-7,28H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Displacement of [1,2,6,7-3H]progesterone from recombinant human GST-tagged PGR LBD (678 to 933 residues) expressed in baculovirus-infected insect cel...				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50367063 (CHEMBL4174199) Show SMILES Cc1cc(cc2c1[nH]c(=O)c1ccccc21)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H11F6NO2/c1-8-6-9(15(26,16(18,19)20)17(21,22)23)7-12-10-4-2-3-5-11(10)14(25)24-13(8)12/h2-7,26H,1H3,(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50367116 (CHEMBL4167377) Show SMILES Cc1cc(cc2c1n(C)c(=O)c1ccccc21)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C18H13F6NO2/c1-9-7-10(16(27,17(19,20)21)18(22,23)24)8-13-11-5-3-4-6-12(11)15(26)25(2)14(9)13/h3-8,27H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50367115 (CHEMBL4171805) Show SMILES CCc1cc(cc2c3ccccc3c(=O)[nH]c12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C18H13F6NO2/c1-2-9-7-10(16(27,17(19,20)21)18(22,23)24)8-13-11-5-3-4-6-12(11)15(26)25-14(9)13/h3-8,27H,2H2,1H3,(H,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50367126 (CHEMBL4163497) Show SMILES COc1cc(cc2c3ccccc3c(=O)[nH]c12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H11F6NO3/c1-27-12-7-8(15(26,16(18,19)20)17(21,22)23)6-11-9-4-2-3-5-10(9)14(25)24-13(11)12/h2-7,26H,1H3,(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50367097 (CHEMBL4173799) Show SMILES Cc1cc(cc2c1n(C)c(=O)c1cc(F)ccc21)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C18H12F7NO2/c1-8-5-9(16(28,17(20,21)22)18(23,24)25)6-12-11-4-3-10(19)7-13(11)15(27)26(2)14(8)12/h3-7,28H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at human CMX-AR expressed in HEK293 cells assessed as reduction in dihydrotestosterone-induced transactivation activity after 24 ...				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50367118 (CHEMBL4160128) Show SMILES OC(c1ccc2[nH]c(=O)c3cc(F)ccc3c2c1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C16H8F7NO2/c17-8-2-3-9-10-5-7(14(26,15(18,19)20)16(21,22)23)1-4-12(10)24-13(25)11(9)6-8/h1-6,26H,(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50396595 (CHEMBL2171906) Show SMILES Cn1c2ccc(cc2c2ccccc2c1=O)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H11F6NO2/c1-24-13-7-6-9(15(26,16(18,19)20)17(21,22)23)8-12(13)10-4-2-3-5-11(10)14(24)25/h2-8,26H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50367121 (CHEMBL4175249) Show SMILES Cc1cc(cc2c1[nH]c(=O)c1cc(F)ccc21)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H10F7NO2/c1-7-4-8(15(27,16(19,20)21)17(22,23)24)5-11-10-3-2-9(18)6-12(10)14(26)25-13(7)11/h2-6,27H,1H3,(H,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Displacement of [1,2,6,7-3H]progesterone from recombinant human GST-tagged PGR LBD (678 to 933 residues) expressed in baculovirus-infected insect cel...				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50367120 (CHEMBL4163940) Show SMILES CCCc1cc(cc2c3ccccc3c(=O)[nH]c12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C19H15F6NO2/c1-2-5-10-8-11(17(28,18(20,21)22)19(23,24)25)9-14-12-6-3-4-7-13(12)16(27)26-15(10)14/h3-4,6-9,28H,2,5H2,1H3,(H,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50012248 (CHEMBL1765167) Show SMILES CCCCn1c2cc(OC)c(cc2c2ccccc2c1=O)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C21H19F6NO3/c1-3-4-9-28-16-11-17(31-2)15(19(30,20(22,23)24)21(25,26)27)10-14(16)12-7-5-6-8-13(12)18(28)29/h5-8,10-11,30H,3-4,9H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50012268 (CHEMBL1765172) Show SMILES CCCCn1c2c(OC)cc(cc2c2ccccc2c1=O)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C21H19F6NO3/c1-3-4-9-28-17-15(13-7-5-6-8-14(13)18(28)29)10-12(11-16(17)31-2)19(30,20(22,23)24)21(25,26)27/h5-8,10-11,30H,3-4,9H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50367122 (CHEMBL4164293) Show SMILES OC(c1ccc2[nH]c(=O)c3c(F)cccc3c2c1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C16H8F7NO2/c17-10-3-1-2-8-9-6-7(4-5-11(9)24-13(25)12(8)10)14(26,15(18,19)20)16(21,22)23/h1-6,26H,(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50012269 (CHEMBL3259994) Show SMILES OC(c1ccc2[nH]c(=O)c3ccccc3c2c1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C16H9F6NO2/c17-15(18,19)14(25,16(20,21)22)8-5-6-12-11(7-8)9-3-1-2-4-10(9)13(24)23-12/h1-7,25H,(H,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50367119 (CHEMBL4170774) Show SMILES OC(c1ccc2[nH]c(=O)c3ccc(F)cc3c2c1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C16H8F7NO2/c17-8-2-3-9-10(6-8)11-5-7(1-4-12(11)24-13(9)25)14(26,15(18,19)20)16(21,22)23/h1-6,26H,(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50367117 (CHEMBL1765173) Show SMILES CCCCn1c2ccc(cc2c2ccc(OC)cc2c1=O)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C21H19F6NO3/c1-3-4-9-28-17-8-5-12(19(30,20(22,23)24)21(25,26)27)10-15(17)14-7-6-13(31-2)11-16(14)18(28)29/h5-8,10-11,30H,3-4,9H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50012260 (CHEMBL1091939) Show SMILES CCCCn1c2ccc(cc2c2ccccc2c1=O)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H17F6NO2/c1-2-3-10-27-16-9-8-12(18(29,19(21,22)23)20(24,25)26)11-15(16)13-6-4-5-7-14(13)17(27)28/h4-9,11,29H,2-3,10H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50118690 (3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...) Show SMILES CC1(C)OC(=O)Nc2ccc(cc12)-c1cc(F)cc(c1)C#N Show InChI InChI=1S/C17H13FN2O2/c1-17(2)14-8-11(3-4-15(14)20-16(21)22-17)12-5-10(9-19)6-13(18)7-12/h3-8H,1-2H3,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at human AR assessed as reduction in DHT-induced transactivation				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50012270 (CHEMBL1093517) Show SMILES CCn1c2ccc(cc2c2ccccc2c1=O)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C18H13F6NO2/c1-2-25-14-8-7-10(16(27,17(19,20)21)18(22,23)24)9-13(14)11-5-3-4-6-12(11)15(25)26/h3-9,27H,2H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50367063 (CHEMBL4174199) Show SMILES Cc1cc(cc2c1[nH]c(=O)c1ccccc21)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H11F6NO2/c1-8-6-9(15(26,16(18,19)20)17(21,22)23)7-12-10-4-2-3-5-11(10)14(25)24-13(8)12/h2-7,26H,1H3,(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Displacement of [1,2,6,7-3H]progesterone from recombinant human GST-tagged PGR LBD (678 to 933 residues) expressed in baculovirus-infected insect cel...				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50118690 (3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...) Show SMILES CC1(C)OC(=O)Nc2ccc(cc12)-c1cc(F)cc(c1)C#N Show InChI InChI=1S/C17H13FN2O2/c1-17(2)14-8-11(3-4-15(14)20-16(21)22-17)12-5-10(9-19)6-13(18)7-12/h3-8H,1-2H3,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at human GR assessed as reduction in dexamethasone-induced transactivation				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50367121 (CHEMBL4175249) Show SMILES Cc1cc(cc2c1[nH]c(=O)c1cc(F)ccc21)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H10F7NO2/c1-7-4-8(15(27,16(19,20)21)17(22,23)24)5-11-10-3-2-9(18)6-12(10)14(26)25-13(7)11/h2-6,27H,1H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at human CMX-AR expressed in HEK293 cells assessed as reduction in dihydrotestosterone-induced transactivation activity after 24 ...				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50012279 (CHEMBL1091940) Show SMILES CCCCCCn1c2ccc(cc2c2ccccc2c1=O)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C22H21F6NO2/c1-2-3-4-7-12-29-18-11-10-14(20(31,21(23,24)25)22(26,27)28)13-17(18)15-8-5-6-9-16(15)19(29)30/h5-6,8-11,13,31H,2-4,7,12H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50012238 (CHEMBL1765175) Show SMILES CCCCn1c2ccc(cc2c2c(OC)cccc2c1=O)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C21H19F6NO3/c1-3-4-10-28-15-9-8-12(19(30,20(22,23)24)21(25,26)27)11-14(15)17-13(18(28)29)6-5-7-16(17)31-2/h5-9,11,30H,3-4,10H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50012265 (CHEMBL3259996) Show SMILES CCCn1c2ccc(cc2c2ccccc2c1=O)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C19H15F6NO2/c1-2-9-26-15-8-7-11(17(28,18(20,21)22)19(23,24)25)10-14(15)12-5-3-4-6-13(12)16(26)27/h3-8,10,28H,2,9H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50367114 (CHEMBL1765165) Show SMILES CCCCn1c2ccc(c(OC)c2c2ccccc2c1=O)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C21H19F6NO3/c1-3-4-11-28-15-10-9-14(19(30,20(22,23)24)21(25,26)27)17(31-2)16(15)12-7-5-6-8-13(12)18(28)29/h5-10,30H,3-4,11H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50012273 (CHEMBL1765174) Show SMILES CCCCn1c2ccc(cc2c2cc(OC)ccc2c1=O)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C21H19F6NO3/c1-3-4-9-28-17-8-5-12(19(30,20(22,23)24)21(25,26)27)10-16(17)15-11-13(31-2)6-7-14(15)18(28)29/h5-8,10-11,30H,3-4,9H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50012261 (CHEMBL1093016) Show SMILES CCCCn1c2ccccc2c2ccccc2c1=O Show InChI InChI=1S/C17H17NO/c1-2-3-12-18-16-11-7-6-9-14(16)13-8-4-5-10-15(13)17(18)19/h4-11H,2-3,12H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50012239 (CHEMBL1092222) Show SMILES CCCCn1c2ccc(CC)cc2c2ccccc2c1=O Show InChI InChI=1S/C19H21NO/c1-3-5-12-20-18-11-10-14(4-2)13-17(18)15-8-6-7-9-16(15)19(20)21/h6-11,13H,3-5,12H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50012267 (CHEMBL1093312) Show SMILES CCCCn1c2ccc(C)cc2c2ccccc2c1=O Show InChI InChI=1S/C18H19NO/c1-3-4-11-19-17-10-9-13(2)12-16(17)14-7-5-6-8-15(14)18(19)20/h5-10,12H,3-4,11H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50012264 (CHEMBL1089421) Show SMILES CCCCn1c2ccc(cc2c2ccccc2c1=O)C(C)(C)C Show InChI InChI=1S/C21H25NO/c1-5-6-13-22-19-12-11-15(21(2,3)4)14-18(19)16-9-7-8-10-17(16)20(22)23/h7-12,14H,5-6,13H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50012272 (CHEMBL1088840) Show SMILES CCCCn1c2ccc(CO)cc2c2ccccc2c1=O Show InChI InChI=1S/C18H19NO2/c1-2-3-10-19-17-9-8-13(12-20)11-16(17)14-6-4-5-7-15(14)18(19)21/h4-9,11,20H,2-3,10,12H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50012271 (CHEMBL1093421) Show SMILES CCCCCCCCCn1c2ccc(cc2c2ccccc2c1=O)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C25H27F6NO2/c1-2-3-4-5-6-7-10-15-32-21-14-13-17(23(34,24(26,27)28)25(29,30)31)16-20(21)18-11-8-9-12-19(18)22(32)33/h8-9,11-14,16,34H,2-7,10,15H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50367127 (CHEMBL1765166) Show SMILES CCCCn1c2ccc(cc2c2cccc(OC)c2c1=O)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C21H19F6NO3/c1-3-4-10-28-15-9-8-12(19(30,20(22,23)24)21(25,26)27)11-14(15)13-6-5-7-16(31-2)17(13)18(28)29/h5-9,11,30H,3-4,10H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Nuclear receptor ROR-beta (Homo sapiens (Human))	BDBM50367121 (CHEMBL4175249) Show SMILES Cc1cc(cc2c1[nH]c(=O)c1cc(F)ccc21)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H10F7NO2/c1-7-4-8(15(27,16(19,20)21)17(22,23)24)5-11-10-3-2-9(18)6-12(10)14(26)25-13(7)11/h2-6,27H,1H3,(H,25,26)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at human RORbeta1 expressed in HEK293 cells after 24 hrs by luciferase reporter gene assay				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50367121 (CHEMBL4175249) Show SMILES Cc1cc(cc2c1[nH]c(=O)c1cc(F)ccc21)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H10F7NO2/c1-7-4-8(15(27,16(19,20)21)17(22,23)24)5-11-10-3-2-9(18)6-12(10)14(26)25-13(7)11/h2-6,27H,1H3,(H,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at human CMX-GRalpha expressed in HEK293 cells assessed as reduction in dexamethasone-induced transactivation activity after 24 h...				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50367063 (CHEMBL4174199) Show SMILES Cc1cc(cc2c1[nH]c(=O)c1ccccc21)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H11F6NO2/c1-8-6-9(15(26,16(18,19)20)17(21,22)23)7-12-10-4-2-3-5-11(10)14(25)24-13(8)12/h2-7,26H,1H3,(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at human CMX-GRalpha expressed in HEK293 cells assessed as reduction in dexamethasone-induced transactivation activity after 24 h...				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50367063 (CHEMBL4174199) Show SMILES Cc1cc(cc2c1[nH]c(=O)c1ccccc21)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H11F6NO2/c1-8-6-9(15(26,16(18,19)20)17(21,22)23)7-12-10-4-2-3-5-11(10)14(25)24-13(8)12/h2-7,26H,1H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at human CMX-AR expressed in HEK293 cells assessed as reduction in dihydrotestosterone-induced transactivation activity after 24 ...				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50367063 (CHEMBL4174199) Show SMILES Cc1cc(cc2c1[nH]c(=O)c1ccccc21)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H11F6NO2/c1-8-6-9(15(26,16(18,19)20)17(21,22)23)7-12-10-4-2-3-5-11(10)14(25)24-13(8)12/h2-7,26H,1H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at human GAL4N-fused LXRbeta LBD expressed in HEK293 cells assessed as reduction in T0901317-induced transactivation activity aft...				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair

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